Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (1,414)

Search Parameters:
Keywords = cognitive stimulation

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
35 pages, 2747 KB  
Article
Response Facilitation in Dementia Care: Exploring Engagement Through Social Contexts: A Qualitative Study in Dutch Nursing Homes
by Coosje Hammink, Nienke Moor and Masi Mohammadi
Healthcare 2026, 14(4), 539; https://doi.org/10.3390/healthcare14040539 (registering DOI) - 22 Feb 2026
Abstract
Background/Objectives: Dementia-related cognitive impairments and staffing shortages in nursing homes challenge the possibilities for individually tailored recreational activities, raising the question of how the physical and social environment might be leveraged to stimulate engagement through response facilitation, a form of vicarious incentive motivation [...] Read more.
Background/Objectives: Dementia-related cognitive impairments and staffing shortages in nursing homes challenge the possibilities for individually tailored recreational activities, raising the question of how the physical and social environment might be leveraged to stimulate engagement through response facilitation, a form of vicarious incentive motivation grounded in Social Cognitive Theory. This study examines in which social contexts observing others’ recreational activities can effectively engage residents with moderate to advanced dementia. Methods: A qualitative, scenario-based multiple case study was conducted in four nursing homes (n = 21), using fly-on-the-wall observations, narratives, and three experimentally embedded social contexts (individual, dyadic, group) around familiar leisure activities. Behavioural engagement, mood, and agitation were assessed with validated observational scales (e.g., OERS and MEDLO), complemented by wearable sensor data (HR/PR, HRV/PRV, SCL, and temperature) and video for contextualised interpretation. Results: Across scenarios, non-participating residents showed limited behavioural responses in individual and dyadic settings, while group activities more frequently elicited both observable engagement and physiological markers consistent with attention or cognitive engagement. Observational and physiological data frequently diverged, which may indicate cognitive or emotional engagement even when overt participation or affect remained minimal or appeared negative. Conclusions: Response facilitation appears most likely in structured group activities if supported by explicit social scaffolding, rather than in individual or dyadic constellations alone. Reliance on behavioural observation or environmental design in isolation risks underestimating engagement; multimodal, context-sensitive approaches are recommended to better harness social mechanisms for meaningful participation in dementia care. Future research should integrate contextual factors with physiological measurements and observations as well as further explore patterns of inactivity to distinguish disengagement from subtle forms of cognitive engagement. Full article
(This article belongs to the Special Issue Health Promotion and Long-Term Care for Older Adults)
Show Figures

Figure 1

24 pages, 8821 KB  
Article
Can Soundscapes Carry 40 Hz for Gamma Entrainment?: Evidence from a Pilot EEG Study
by Kiechan Namkung, Kanghyun Lee, Kiseong Kim, Dongjune Yeo, Hyeeun Kim, Seohyun Yoo, Yebeen Lee, Jisen Yuan, Junghun Shin, Sumin Jeon and Mintaek Lim
Appl. Sci. 2026, 16(4), 2063; https://doi.org/10.3390/app16042063 - 19 Feb 2026
Viewed by 129
Abstract
This pilot EEG study examined the feasibility of a soundscape-based 40 Hz auditory stimulation format by using a soundscape-only condition as a contrast control. We tested whether a nature-based soundscape with an additively layered pure 40 Hz sine component (40 Hz ON; not [...] Read more.
This pilot EEG study examined the feasibility of a soundscape-based 40 Hz auditory stimulation format by using a soundscape-only condition as a contrast control. We tested whether a nature-based soundscape with an additively layered pure 40 Hz sine component (40 Hz ON; not amplitude-modulated) yields a more pronounced narrowband response centered at 40 Hz than the same soundscape without the 40 Hz layer (40 Hz OFF). Participants completed both conditions in a single-blind, randomized-order, within-participant crossover session with a washout interval. EEG outcomes included 40 Hz power, frequency-domain SNR around 40 Hz, scalp distribution of 40 Hz power, and phase-based connectivity in the gamma range. This study evaluates EEG-level detectability of 40 Hz–centered neural signatures and does not assess cognitive/clinical efficacy or therapeutic benefit. Across metrics, the 40 Hz ON soundscape showed a consistent ON > OFF directionality, including localized electrode-level signals and a temporal-region summary measure under nominal, uncorrected testing, accompanied by a clearer narrowband feature near 40 Hz in spectral profiles. Overall, the observed trends are consistent with the feasibility of embedding an additive 40 Hz layer into a naturalistic soundscape in a manner that yields EEG-quantifiable, 40 Hz centered signatures; however, because this is an exploratory pilot without multiplicity control, all effects should be interpreted as hypothesis-generating and warrant confirmation in larger, preregistered studies with multiplicity-aware inference. Full article
(This article belongs to the Section Applied Biosciences and Bioengineering)
Show Figures

Figure 1

24 pages, 1110 KB  
Article
Acceptability and Implementation Considerations for 40 Hz Auditory Stimulation Using Nature-Based Soundscapes for Cognitive Health Applications: A Qualitative Exploratory Study
by Kiechan Namkung and Kanghyun Lee
Healthcare 2026, 14(4), 512; https://doi.org/10.3390/healthcare14040512 - 17 Feb 2026
Viewed by 166
Abstract
Background/Objectives: 40 Hz sensory stimulation is being explored for cognitive health applications, but sustained use may be constrained by the listenability of simple 40 Hz auditory stimuli. We examined user-perceived acceptability and implementation considerations for 40 Hz auditory stimulation delivered by embedding a [...] Read more.
Background/Objectives: 40 Hz sensory stimulation is being explored for cognitive health applications, but sustained use may be constrained by the listenability of simple 40 Hz auditory stimuli. We examined user-perceived acceptability and implementation considerations for 40 Hz auditory stimulation delivered by embedding a pure 40 Hz sine wave within nature-based soundscapes. Methods: Eleven adults aged ≥ 40 years in Seoul, Republic of Korea were assigned to waves or forest soundscapes (between-participants) and completed a within-session exposure to two conditions within the assigned set: 40 Hz–OFF (soundscape-only) and 40 Hz–ON (soundscape plus an additively layered 40 Hz sine wave). Each condition comprised seven cycles of 50 s playback and 10 s silence (~7 min) with a 10 min washout. After completing both listening blocks, participants provided brief comparative session-end ratings to aid recall and then completed a semi-structured interview focused on detectability and comparative impressions while blinded to condition identity. Following debriefing about the 40 Hz manipulation, participants completed a session-end 7-point Likert appraisal of the intended intervention stimulus (40 Hz–ON). Interview transcripts were analyzed using thematic analysis and interpreted using the Theoretical Framework of Acceptability and Proctor et al.’s implementation outcomes as sensitizing frameworks. Results: Session-end appraisals suggested that the 40 Hz-integrated soundscape (40 Hz–ON) was generally listenable, with mid-to-high comfort and immersion (medians = 5) and low unpleasantness (median = 2), while perceived artificiality spanned the full scale (range 1–7) and overall preference was moderate (median = 4). Interviews indicated that acceptability was governed by perceptual integration: natural blending supported “backgroundable” listening, whereas salient low-frequency rumble or a mechanical/artificial timbre contributed to negative reactions. Implementation-relevant themes highlighted context fit (bedtime vs. morning routines), low-friction automation (timers/scheduling), and conservative acoustic safeguards (gentle onset and default levels). Conclusions: In a single-session evaluation among adults aged ≥ 40 years, embedding a 40 Hz sine wave within nature-based soundscapes was generally acceptable, with acceptability sensitive to perceptual integration and usage context. This qualitative study does not assess clinical or cognitive efficacy. These findings inform implementation considerations for cognitive health-oriented delivery, including space-oriented playback options, simplified automation, conservative acoustic safeguards, and coherence-supportive user guidance without overclaiming. Full article
(This article belongs to the Section Digital Health Technologies)
Show Figures

Figure 1

26 pages, 1815 KB  
Article
AI-Generated Dialogic Feedback: Designing a Pedagogical Chatbot Grounded in Literacy Resilience Principles
by Alisa Amir
Educ. Sci. 2026, 16(2), 318; https://doi.org/10.3390/educsci16020318 - 16 Feb 2026
Viewed by 127
Abstract
Artificial intelligence (AI) has reshaped contemporary approaches to teaching, assessment, and feedback. Most AI systems provide reactive feedback, offering instant answers that reduce learners’ cognitive engagement and sense of agency. In contrast, Mili was developed as a proactive pedagogical intelligence that asks guiding [...] Read more.
Artificial intelligence (AI) has reshaped contemporary approaches to teaching, assessment, and feedback. Most AI systems provide reactive feedback, offering instant answers that reduce learners’ cognitive engagement and sense of agency. In contrast, Mili was developed as a proactive pedagogical intelligence that asks guiding questions and encourages learners to construct their own responses. Through this design, feedback becomes a process of learning rather than an evaluative mechanism. Mili is a Hebrew-language educational chatbot grounded in principles of dialogic feedback, pedagogical mediation, and literacy resilience. Its goal is to create a metacognitive literacy dialogue in which questions replace answers and learning becomes an act of reflection and self-inquiry. The development followed a Design-Based Research approach involving iterative cycles of design, training, and testing. At each stage, pedagogical prompts were crafted to simulate authentic teacher–learner dialogue, including clarifying questions, pedagogical delay, and emotional reinforcement. This process enabled an exploration of how AI can mediate feedback that stimulates deeper cognitive engagement. The resulting model demonstrates proactive dialogic feedback in which AI does not simply respond but initiates reflective dialogue. Simulated interactions with Mili reveal how such feedback supports the three dimensions of literacy resilience: linguistic-cognitive, metacognitive, and emotional. Mili represents a conceptual shift in AI-based feedback, moving from response to process, from outcome to mediation, and from reactive AI to learning-generative AI. The study makes a theoretical contribution by articulating a model of pedagogically mediated AI and a practical contribution by developing a feedback tool that fosters inquiry, reflection, and literacy resilience in learners and teachers. Full article
Show Figures

Figure 1

34 pages, 7022 KB  
Article
Quantitative Perceptual Analysis of Feature-Space Scenarios in Network Media Evaluation Using Transformer-Based Deep Learning: A Case Study of Fuwen Township Primary School in China
by Yixin Liu, Zhimin Li, Lin Luo, Simin Wang, Ruqin Wang, Ruonan Wu, Dingchang Xia, Sirui Cheng, Zejing Zou, Xuanlin Li, Yujia Liu and Yingtao Qi
Buildings 2026, 16(4), 714; https://doi.org/10.3390/buildings16040714 - 9 Feb 2026
Viewed by 283
Abstract
Against the dual backdrop of the rural revitalization strategy and the pursuit of high-quality, balanced urban–rural education, optimizing rural campus spaces has emerged as an important lever for addressing educational resource disparities and improving pedagogical quality. However, conventional evaluation of campus space optimization [...] Read more.
Against the dual backdrop of the rural revitalization strategy and the pursuit of high-quality, balanced urban–rural education, optimizing rural campus spaces has emerged as an important lever for addressing educational resource disparities and improving pedagogical quality. However, conventional evaluation of campus space optimization faces two systemic dilemmas. First, top-down decision-making often neglects the authentic needs of diverse stakeholders and place-based knowledge, resulting in spatial interventions that lose regional distinctiveness. Second, routine public participation is constrained by geographical barriers, time costs, and sample-size limitations, which can amplify professional cognitive bias and impede comprehensive feedback formation. The compounded effect of these challenges contributes to a disconnect between spatial optimization outcomes and perceived needs, thereby constraining the distinctive development of rural educational spaces. To address these constraints, this study proposes a novel method that integrates regional spatial feature recognition with digital media-based public perception assessment. At the data collection and ethical governance level, the study strictly adheres to platform compliance and academic ethics. A total of 12,800 preliminary comments were scraped from major social media platforms (e.g., Douyin, Dianping, and Xiaohongshu) and processed through a three-stage screening workflow—keyword screening–rule-based filtering–manual verification—to yield 8616 valid records covering diverse public groups across China. All user-identifying information was fully anonymized to ensure lawful use and privacy protection. At the analytical modeling level, we develop a Transformer-based deep learning system that leverages multi-head attention mechanisms to capture implicit spatial-sentiment features and metaphorical expressions embedded in review texts. Evaluation on an independent test set indicates a classification accuracy of 89.2%, aligning with balanced and stable scoring performance. Robustness is further strengthened by introducing an equal-weight alternative strategy and conducting stability checks to indicate the consistency of model outputs across weighting assumptions. At the scenario interpretation level, we combine grounded-theory coding with semantic network analysis to establish a three-tier spatial analysis framework—macro (landscape pattern/hydro-topological patterns), meso (architectural interface), and micro (teaching scenes/pedagogical scenarios)—and incorporate an interpretive stakeholder typology (tourists, residents, parents, and professional groups) to systematically identify and quantify key features shaping public spatial perception. Findings show that, at the macro level, naturally integrated scenarios—such as “campus–farmland integration” and “mountain–water embeddedness”—exhibit high affective association, aligning with the “mountain-water-field-village” spatial sequence logic and suggesting broad public endorsement of ecological campus concepts, whereas vernacular settlement-pattern scenarios receive relatively low attention due to cognitive discontinuities. At the meso level, innovative corridor strategies (e.g., framed vistas and expanded corridor spaces) strengthen the building–nature interaction and suggest latent value in stimulating exploratory spatial experience. At the micro level, place-based practice-oriented teaching scenes (e.g., intangible cultural heritage handcraft and creative workshops) achieve higher scores, aligning with the compatibility of vernacular education’s “differential esthetics,” while urban convergence-oriented interdisciplinary curriculum scenes suggest an interpretive gap relative to public expectations. These results indicate an embedded relationship between public perception and regional spatial features, which is further shaped by a multi-actor governance process—characterized by “Government + Influencers + Field Study”—that mediates how rural educational spaces are produced, communicated, and interpreted in digital environments. The study’s innovative value lies in integrating sociological theories (e.g., embeddedness) with deep learning techniques to fill the regional and multi-actor perspective gap in rural campus POE and to promote a methodological shift from “experience-based induction” toward a “data-theory” dual-drive model. The findings provide inferential evidence for rural campus renewal and optimization; the methodological pipeline is transferable to small-scale rural primary schools with media exposure and salient regional ecological characteristics, and it offers a new pathway for incorporating digital media-driven public perception feedback into planning and design practice. The research methodology of this study consists of four sequential stages, which are implemented in a systematic and progressive manner: First, data collection was conducted: Python and the Octopus Collector were used to crawl online comment data related to Fuwen Township Central Primary School, strictly complying with the user agreements of the Douyin, Dianping, and Xiaohongshu platforms. Second, semantic preprocessing was performed: The evaluation content was segmented to generate word frequency statistics and semantic networks; qualitative analysis was conducted using Origin software, and quantitative translation was realized via Sankey diagrams. Third, spatial scene coding was carried out: Combined with a spatial characteristic identification system, a macro–meso–micro three-tier classification system for spatial scene characteristics was constructed to encode and quantitatively express the textual content. Finally, sentiment quantification and correlation analysis was implemented: A deep learning model based on the Transformer framework was employed to perform sentiment quantification scoring for each comment; Sankey diagrams were used to quantitatively correlate spatial scenes with sentiment tendencies, thereby exploring the public’s perceptual associations with the architectural spatial environment of rural campuses. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
Show Figures

Figure 1

12 pages, 275 KB  
Article
The Impact of Inclusive Leadership on Employee Innovative Behavior: The Chain Mediating Role of Employee Positive Emotions and Creative Self-Efficacy
by Jiahui He and Delong Li
Adm. Sci. 2026, 16(2), 84; https://doi.org/10.3390/admsci16020084 - 8 Feb 2026
Viewed by 288
Abstract
Employee innovative behavior is an important source of organizational competitiveness and sustainable development. Accordingly, increasing scholarly attention has been directed toward how leadership behaviors are associated with employees’ innovative actions. Drawing on Affective Events Theory and the ABC Theory of Emotion, this study [...] Read more.
Employee innovative behavior is an important source of organizational competitiveness and sustainable development. Accordingly, increasing scholarly attention has been directed toward how leadership behaviors are associated with employees’ innovative actions. Drawing on Affective Events Theory and the ABC Theory of Emotion, this study develops a cognition–emotion–attitude–behavior framework to examine the relationships among inclusive leadership, positive emotions, creative self-efficacy, and employee innovative behavior. Using a questionnaire survey, data were collected from 463 employees working in innovation-oriented enterprises. Hierarchical regression analyses and bootstrap procedures were employed to examine the proposed associations and indirect effects. Inclusive leadership plays a positive role in stimulating employee innovation. Moreover, positive emotions and creative self-efficacy each exhibit significant indirect associations linking inclusive leadership to employee innovative behavior. This study contributes to the literature by clarifying the affective and attitudinal processes associated with inclusive leadership and by enriching understanding of the psychological pathways linked to employee innovative behavior. Full article
(This article belongs to the Special Issue The Psychology of Employee Motivation)
Show Figures

Figure 1

14 pages, 3289 KB  
Brief Report
iTBS Stimulation of the Bilateral IFG/IPL Alters the Oscillatory Pattern in ASD
by Mitra Assadi, Reza Koiler, Ryan Ally, Richard Fischer and Rodney Scott
Brain Sci. 2026, 16(2), 192; https://doi.org/10.3390/brainsci16020192 - 6 Feb 2026
Viewed by 260
Abstract
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impairments in social communication, reciprocity, and adaptive behavior. Converging neurobiological evidence suggests that these clinical features arise from aberrant connectivity and dysregulated neuronal oscillations across distributed brain networks. In particular, dysfunction within [...] Read more.
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impairments in social communication, reciprocity, and adaptive behavior. Converging neurobiological evidence suggests that these clinical features arise from aberrant connectivity and dysregulated neuronal oscillations across distributed brain networks. In particular, dysfunction within the mirror neuron regions, concentrated in the inferior frontal gyrus (IFG) and inferior parietal lobule (IPL), has been implicated in deficits of imitation, empathy, and social cognition in ASD. Non-invasive neuromodulation using repetitive transcranial magnetic stimulation (rTMS) has shown modest behavioral benefits in ASD. However, most studies apply the conventional protocols targeting the dorsolateral prefrontal cortex. The effects of intermittent theta-burst stimulation (iTBS), a potent excitatory rTMS protocol targeting the mirror neuron regions, on the oscillatory dynamics in ASD remain largely unexplored. Objective: To investigate whether iTBS targeting the bilateral IFG and IPL modulates EEG-derived oscillatory activity in adolescents with ASD and to explore the relationship between oscillatory changes and social reciprocity. Methods: Six adolescents with Level I or II ASD (ages 13–18) underwent bilateral iTBS targeting the IFG and IPL using a figure-of-eight coil and standardized theta-burst parameters. Participants were randomized to receive either 18 active iTBS sessions or a waitlist-controlled crossover design (9 sham followed by 9 active sessions). Standard 21-channel EEG recordings were obtained during the first (EEG-1) and final (EEG-2) active stimulation sessions, including pre- and post-stimulation epochs. Power spectral analyses were conducted across frequency bands (delta through gamma). Behavioral outcomes were assessed using the Childhood Autism Rating Scale, Second Edition (CARS2), administered pre- and post-intervention. Results: All participants tolerated the intervention without adverse effects. Behavioral analysis demonstrated a significant reduction in CARS2 scores following iTBS and is reported in detail in our prior clinical outcomes manuscript, consistent with improved social reciprocity (p < 0.001). EEG analysis revealed an immediate post-stimulation increase in gamma-band power during EEG-1 in five of six participants, whereas lower-frequency bands exhibited variable responses. In contrast, EEG-2 showed no consistent post-stimulation gamma enhancement. Net comparisons between EEG-1 and EEG-2 demonstrated attenuation of the initial gamma response in the same five participants. At the group level, gamma percent change did not reach statistical significance at EEG-1 (p = 0.12) or EEG-2 (p = 0.66), and exploratory comparisons between the 9-active versus 18-active arms did not reach statistical significance. While ipsi-directional changes in gamma power and CARS2 scores were observed in four participants, correlation was not identified in this pilot sample. Conclusions: Bilateral iTBS targeting the IFG and IPL induces a transient enhancement of gamma oscillations in adolescents with ASD that attenuates with repeated stimulation. This pattern is consistent with adaptive homeostatic plasticity (metaplasticity) within excitatory–inhibitory circuits, potentially mediated by GABAergic interneurons. These findings support the feasibility of EEG as an objective biomarker of neuromodulatory engagement in ASD and highlight the importance of network-level and oscillatory mechanisms in interpreting therapeutic responses. Larger, sham-controlled studies incorporating multimodal biomarkers are warranted to clarify clinical relevance and optimize personalized neuromodulation strategies. Full article
(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
Show Figures

Figure 1

19 pages, 1329 KB  
Article
Effects of a Strength and Creative Dance Intervention on Brain Electrical Activity, Heart Rate Variability, and Dual-Task Performance in Women with Fibromyalgia: A Randomized Controlled Trial Protocol
by Maria Melo-Alonso, Carmen Padilla-Moledo, Almudena Martínez-Sánchez, Lucimere Bohn, Pablo Molero, Francisco Javier Dominguez-Muñoz, Santos Villafaina, Pedro R. Olivares, Inmaculada Tornero-Quiñones, Juan Luis Leon-Llamas and Narcis Gusi
Sports 2026, 14(2), 59; https://doi.org/10.3390/sports14020059 - 4 Feb 2026
Viewed by 245
Abstract
Fibromyalgia is a complex chronic disorder involving persistent widespread pain accompanied by functional limitations, cognitive impairments, and alterations in neural processing. Previous research indicates that exercise-based interventions can play a key role in alleviating symptom burden and enhancing physical performance; however, there is [...] Read more.
Fibromyalgia is a complex chronic disorder involving persistent widespread pain accompanied by functional limitations, cognitive impairments, and alterations in neural processing. Previous research indicates that exercise-based interventions can play a key role in alleviating symptom burden and enhancing physical performance; however, there is limited evidence regarding their impact on neurophysiological mechanisms. Creative dance, in combination with strength training, may stimulate both motor and cognitive systems, promoting brain plasticity and functional improvements. This study will analyze the effects of a six-week strength and creative dance program on physical fitness under single- and dual-task conditions in women with fibromyalgia and will explore the associated changes in brain electrical activity and autonomic modulation. Methods: This randomized controlled trial will be divided into an exercise group (n = 22) and a control group (n = 22). The 6-week supervised intervention consists of two 60-min sessions per week, combining strength exercises and creative dance. Primary outcomes include physical fitness tests (strength, mobility, balance, and agility gait test in single-task and dual-task), fibromyalgia symptoms, and quality of life. Secondary outcomes include changes in electroencephalography, heart rate variability, physical activity level, and fear of falling. Statistical analyses will compare within- and between-group differences using non-parametric tests and effect sizes. It is hypothesized that the intervention will improve physical fitness and dual-task performance, alongside increases in brain activity power. This study may provide insights into the neurophysiological mechanisms underlying the benefits of exercise benefits in fibromyalgia. Full article
Show Figures

Graphical abstract

18 pages, 330 KB  
Article
Moderating Role of Cigarette Smoking on the Efficacy of tDCS in the Treatment of Negative and Cognitive Symptoms of Schizophrenia: Results from a Randomized Clinical Trial
by Jacopo Lisoni, Gabriele Nibbio, Mattia Ardesi, Antonio Baglioni, Lorenzo Bertoni, Francesco Bezzi, Camilla Agnese Carolina Cicolari, Federica Frigerio, Michela Gregorelli, Paola Miotto, Giacomo Deste, Stefano Barlati and Antonio Vita
Brain Sci. 2026, 16(2), 186; https://doi.org/10.3390/brainsci16020186 - 3 Feb 2026
Viewed by 248
Abstract
Background: Transcranial Direct Current Stimulation (tDCS) has shown potential in improving negative symptoms (NS) and Cognitive Impairment Associated with Schizophrenia (CIAS). However, heterogeneity in stimulation protocols and sample characteristics limit definitive conclusions regarding tDCS effectiveness in schizophrenia. Given the detrimental effects of cigarette [...] Read more.
Background: Transcranial Direct Current Stimulation (tDCS) has shown potential in improving negative symptoms (NS) and Cognitive Impairment Associated with Schizophrenia (CIAS). However, heterogeneity in stimulation protocols and sample characteristics limit definitive conclusions regarding tDCS effectiveness in schizophrenia. Given the detrimental effects of cigarette smoking, particularly on cognition, this study explored the role of cigarette smoking as a modifiable individual factor potentially contributing to methodological heterogeneity by evaluating tDCS effects on NS and CIAS in Smoker (SM) and Non-Smoker (NoSM) patients. Methods: Post hoc analyses of a double-blind RCT were performed on 50 patients, randomized to 2 mA active or sham-tDCS (15 weekday sessions) with bilateral bipolar-nonbalanced prefrontal placement. The sample was divided according to the smoking status, consisting of 28 SM and 22 NoSM. Separate one-way analyses of covariance (ANCOVA) were performed within each subgroup to assess changes over time between treatment conditions. Clinical outcomes included Positive and Negative Symptoms Scale (PANSS), Brief Assessment of Cognition in Schizophrenia (BACS), Clinical Global Impression (CGI) and Calgary Depression Scale for Schizophrenia (CDSS) total scores. Results: SM exhibited baseline lower cognitive scores in verbal memory, motor speed and working memory domains. NS improved in both SM and NoSM with large effect size. Significant improvement in CIAS, specifically in working memory and verbal fluency, were found exclusively in NoSM. Conclusions: Cigarette smoking appeared to limit tDCS effectiveness in improving CIAS but not NS in schizophrenia. We suggested that the neurotoxic milieu linked to chronic exposure to neurotoxins of cigarette smoking could be responsible for these effects, counterbalancing the neuroprotective effects of tDCS. Further studies are warranted to replicate these findings. Full article
31 pages, 5677 KB  
Article
Semantic Network Simulation vs. Traditional Brainstorming: Enhancing Architectural Design Conflict Resolution and Innovation
by Jun Dong and Zijia Wang
Buildings 2026, 16(3), 609; https://doi.org/10.3390/buildings16030609 - 2 Feb 2026
Viewed by 192
Abstract
Comprehensive design thinking is vital for architects to resolve spatial conflicts in architectural design. To address the limitations of traditional brainstorming (TB) in complex constraint scenarios, this study proposes a cognitive science-based semantic network simulation (SN) method. A controlled experiment was conducted with [...] Read more.
Comprehensive design thinking is vital for architects to resolve spatial conflicts in architectural design. To address the limitations of traditional brainstorming (TB) in complex constraint scenarios, this study proposes a cognitive science-based semantic network simulation (SN) method. A controlled experiment was conducted with 60 architecture students randomly divided into SN and TB groups, tasked with solving the same rural cultural center entrance design conflict within 10 min, with eye-tracking monitoring subconscious thinking. Multi-dimensional evaluation shows TB generates more proposals, but SN outperforms TB in innovation, conflict resolution, and thought explicitness. For architects, SN provides a structured thinking tool: decompose design conflicts into nodes, establish logical connections, and generate innovative solutions through cross-domain association. The findings offer actionable methods for architectural design practice and education, helping break the “function–innovation–efficiency” trade-off. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
Show Figures

Figure 1

27 pages, 368 KB  
Review
Technology Interventions and Well-Being Enhancement in Residential Aged Care: A Scoping Review
by Michael Chew, Sonja Pedell, Diego Muñoz and Marija Basic
Technologies 2026, 14(2), 90; https://doi.org/10.3390/technologies14020090 - 1 Feb 2026
Viewed by 209
Abstract
Technology interventions have great potential to support the complex needs of older adults living in residential aged care, contributing to their general well-being. This scoping review aims to provide an overview of how different technological interventions contribute to the well-being of older adult [...] Read more.
Technology interventions have great potential to support the complex needs of older adults living in residential aged care, contributing to their general well-being. This scoping review aims to provide an overview of how different technological interventions contribute to the well-being of older adult residents in aged care settings. Specifically, the current objectives for digital interventions, the interaction mechanisms, and the evaluation of their impact on well-being are reviewed following the PRISMA guidelines. We included 26 studies since 2017 covering three databases discussing the impact of technological interventions on social connectedness and cognitive and emotional well-being, and the theoretical models of evaluation applied in these studies. Seven key interaction mechanisms with digital interventions with the objective to enhance social connections, stimulate cognitive functioning, and formulate new models and theories were identified. Our findings show the potential of enhancing the well-being of aged care residents. We discuss our findings under three lenses: User, relational, and contextual experiences, and suggest that these experience categories should inform the focus of future research. This review offers insights into the broader ethical, social, and contextual factors that influence their success, and that can guide future research, inform policy decisions, and improve care practices. Full article
(This article belongs to the Section Assistive Technologies)
Show Figures

Figure 1

16 pages, 3865 KB  
Article
Combined Bacopa, Phosphatidylserine, and Choline Protect Against Stress-Induced Neurotoxicity
by Chiara Sasia, Giacomina Videtta and Nicoletta Galeotti
Biomedicines 2026, 14(2), 340; https://doi.org/10.3390/biomedicines14020340 - 1 Feb 2026
Viewed by 299
Abstract
Background/Objectives: Chronic stress leads to sustained elevations in cortisol levels, which promote neuronal damage and impair memory. Prolonged stress also enhances proinflammatory signaling. Adaptogens are plant-derived compounds associated with the ability to increase the body’s resistance to stress, thereby improving mental and [...] Read more.
Background/Objectives: Chronic stress leads to sustained elevations in cortisol levels, which promote neuronal damage and impair memory. Prolonged stress also enhances proinflammatory signaling. Adaptogens are plant-derived compounds associated with the ability to increase the body’s resistance to stress, thereby improving mental and physical performance. To identify potential interventions capable of attenuating stress-related memory alterations, this study investigated a formulation combining the adaptogen Bacopa monnieri L. with phosphatidylserine and choline (BPC). Methods: An in vitro model of stress-related neuroinflammation was established by exposing BV2 microglial cells to corticotropin-releasing hormone (CRH, 100 nM). SH-SY5Y cells exposed to conditioned medium from CRH-stimulated BV2 cells or to iron(II) sulfate and L-ascorbic acid (Fe/Asc) were used as models of neurotoxicity. Results: BPC attenuated CRH-induced proinflammatory microglial morphology, as well as the reduction in cell viability and cell number. BPC treatment restored the levels of stress-related markers, including SIRT-1, Nrf-2, and phosphorylated JNK (p-JNK). Furthermore, BPC protected against neurotoxicity induced by CRH and Fe/Asc and promoted cholinergic activation by restoring basal acetylcholinesterase (AChE) levels. The combined BPC formulation showed superior efficacy compared with its individual components across all experimental assays. Conclusions: Collectively, these findings indicate that the BPC formulation developed in this study effectively attenuates stress-related neuroinflammation and neurotoxicity. BPC may represent a promising strategy to help limit the progression of early cognitive dysfunction under conditions of prolonged stress. Full article
(This article belongs to the Section Neurobiology and Clinical Neuroscience)
Show Figures

Figure 1

27 pages, 658 KB  
Review
Theoretical, Technical, and Analytical Foundations of Task-Based and Resting-State Functional Magnetic Resonance Imaging (fMRI)—A Narrative Review
by Natalia Anna Koc, Maurycy Rakowski, Anna Dębska, Bartosz Szmyd, Agata Zawadzka, Karol Zaczkowski, Małgorzata Podstawka, Dagmara Wilmańska, Adam Dobek, Ludomir Stefańczyk, Dariusz Jan Jaskólski and Karol Wiśniewski
Biomedicines 2026, 14(2), 333; https://doi.org/10.3390/biomedicines14020333 - 31 Jan 2026
Viewed by 394
Abstract
Functional magnetic resonance imaging (fMRI) is a valuable tool for presurgical brain mapping, traditionally implemented with task-based paradigms (tb-fMRI) that measure blood oxygenation level-dependent (BOLD) signal changes during controlled motor or cognitive tasks. Tb-fMRI is a well-established tool for non-invasive localization of cortical [...] Read more.
Functional magnetic resonance imaging (fMRI) is a valuable tool for presurgical brain mapping, traditionally implemented with task-based paradigms (tb-fMRI) that measure blood oxygenation level-dependent (BOLD) signal changes during controlled motor or cognitive tasks. Tb-fMRI is a well-established tool for non-invasive localization of cortical eloquent areas, yet its dependence on patient cooperation and intact cognition limits use in individuals with aphasia, cognitive impairment, or in pediatric and other vulnerable populations. Resting-state fMRI (rs-fMRI) provides a task-free alternative by leveraging spontaneous low-frequency BOLD fluctuations to delineate intrinsic functional networks, including motor and language systems that show good spatial concordance with tb-fMRI and with direct cortical stimulation. This narrative review outlines the methodological foundations of tb-fMRI and rs-fMRI, comparing acquisition protocols, preprocessing and denoising pipelines, analytic approaches, and validation strategies relevant to presurgical planning. Particular emphasis is given to the technical and physiological foundations of BOLD imaging, statistical modeling, and the influence of motion, noise, and standardization on data reliability. Emerging evidence indicates that rs-fMRI can reliably expand mapping to patients with limited task compliance and may serve as a robust complementary modality in complex clinical contexts, though its methodological heterogeneity and absence of unified practice guidelines currently constrain widespread adoption. Future advances in harmonized preprocessing, multicenter validation, and integration with connectomics and machine learning frameworks are likely to be critical for translating rs-fMRI into routine, reliable presurgical workflows. Full article
Show Figures

Figure 1

11 pages, 222 KB  
Article
Applying Cognitive Stimulation Therapy (CST) on People with Concurrent Visual Impairment and Dementia: A Preliminary Study
by Hiu Tung Tsang, Chun Lam Luk, Yee Lam Lo, Armstrong Tat San Chiu, Ben Chi Bun Yip and Winsy Wing Sze Wong
Brain Sci. 2026, 16(2), 168; https://doi.org/10.3390/brainsci16020168 - 30 Jan 2026
Viewed by 364
Abstract
Background/Objectives: This pilot study explored the applicability and preliminary clinical outcomes of cognitive stimulation therapy (CST), an evidence-based cognitive intervention for people with mild and moderate dementia, in elderly individuals with concurrent dementia and visual impairment. Methods: Seven participants received 14 group CST [...] Read more.
Background/Objectives: This pilot study explored the applicability and preliminary clinical outcomes of cognitive stimulation therapy (CST), an evidence-based cognitive intervention for people with mild and moderate dementia, in elderly individuals with concurrent dementia and visual impairment. Methods: Seven participants received 14 group CST sessions. Their cognitive and language functions were measured and compared pre-/post-therapy. Results: The treatment adherence was satisfactory. Significant improvements in various cognitive domains and language measures were observed after therapy. Conclusions: The findings suggest that CST can be applied to visually impaired individuals with dementia with seemingly positive outcomes in various cognitive domains. Further studies with a larger sample with an emphasis on multisensory stimulation to facilitate therapy delivery are warranted. Full article
24 pages, 449 KB  
Article
Digital Learning and Usage Practices of German Students in a Continuum of Formal and Informal Contexts—Results of a Diary Study
by Therese Rosemann
Educ. Sci. 2026, 16(2), 208; https://doi.org/10.3390/educsci16020208 - 29 Jan 2026
Viewed by 340
Abstract
In the “culture of digitality”, new (digital) spaces of opportunity in the contested field of formal and informal learning contexts are constantly emerging, forcing students to orient themselves and take responsibility for selecting information. To deal with the associated challenges (e.g., cognitive overload) [...] Read more.
In the “culture of digitality”, new (digital) spaces of opportunity in the contested field of formal and informal learning contexts are constantly emerging, forcing students to orient themselves and take responsibility for selecting information. To deal with the associated challenges (e.g., cognitive overload) this brings, digital skills are required, which can be acquired through various learning and usage practices. The aim of this study is to examine the interplay between students’ individual (digital) learning environments and their (digital) learning and usage practices, which are shaped by the culture of digitality, to derive actionable recommendations for the promotion of digital competencies. Thus, the multivariate results of a quantitative 10-day diary study with 70 students from a German University demonstrate that merely owning digital media is not sufficient to stimulate processes for developing digital competencies. Instead, students need to be encouraged to use these media in a way that actively promotes learning and reflection. Against the backdrop of these findings, there is a discussion about how learning environments can be designed to support and accompany students’ individual digital learning practices. Full article
(This article belongs to the Special Issue Investigating Informal Learning in the Age of Technology)
Show Figures

Figure 1

Back to TopTop