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Keywords = ellipsoidal particles

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14 pages, 5730 KB  
Article
Offline Magnetometer Calibration Using Enhanced Particle Swarm Optimization
by Lei Huang, Zhihui Chen, Jun Guan, Jian Huang and Wenjun Yi
Mathematics 2025, 13(15), 2349; https://doi.org/10.3390/math13152349 - 23 Jul 2025
Viewed by 236
Abstract
To address the decline in measurement accuracy of magnetometers due to process errors and environmental interference, as well as the insufficient robustness of traditional calibration algorithms under strong interference conditions, this paper proposes an ellipsoid fitting algorithm based on Dynamic Adaptive Elite Particle [...] Read more.
To address the decline in measurement accuracy of magnetometers due to process errors and environmental interference, as well as the insufficient robustness of traditional calibration algorithms under strong interference conditions, this paper proposes an ellipsoid fitting algorithm based on Dynamic Adaptive Elite Particle Swarm Optimization (DAEPSO). The proposed algorithm integrates three enhancement mechanisms: dynamic stratified elite guidance, adaptive inertia weight adjustment, and inferior particle relearning via Lévy flight, aiming to improve convergence speed, solution accuracy, and noise resistance. First, a magnetometer calibration model is established. Second, the DAEPSO algorithm is employed to fit the ellipsoid parameters. Finally, error calibration is performed based on the optimized ellipsoid parameters. Our simulation experiments demonstrate that compared with the traditional Least Squares Method (LSM) the proposed method reduces the standard deviation of the total magnetic field intensity by 54.73%, effectively improving calibration precision in the presence of outliers. Furthermore, when compared to PSO, TSLPSO, MPSO, and AWPSO, the sum of the absolute distances from the simulation data to the fitted ellipsoidal surface decreases by 53.60%, 41.96%, 53.01%, and 27.40%, respectively. The results from 60 independent experiments show that DAEPSO achieves lower median errors and smaller interquartile ranges than comparative algorithms. In summary, the DAEPSO-based ellipsoid fitting algorithm exhibits high fitting accuracy and strong robustness in environments with intense interference noise, providing reliable theoretical support for practical engineering applications. Full article
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24 pages, 11650 KB  
Article
Particle-Scale Insights into Extraction Zone Development During Block Caving: Experimental Validation and PFC3D Simulation of Gradation-Dependent Flow Characteristics
by Chaoyi Yang, Guangquan Li, Dengjun Gan, Rihong Cao, Hang Lin and Rugao Gao
Appl. Sci. 2025, 15(14), 7916; https://doi.org/10.3390/app15147916 - 16 Jul 2025
Viewed by 257
Abstract
To investigate the evolution trend of the extraction zone above the drawbell in block caving, an experimental apparatus incorporating the drawbell structure was designed. Ore drawing experiments were conducted using materials with varying particle size gradations. The results demonstrate that the extraction zones [...] Read more.
To investigate the evolution trend of the extraction zone above the drawbell in block caving, an experimental apparatus incorporating the drawbell structure was designed. Ore drawing experiments were conducted using materials with varying particle size gradations. The results demonstrate that the extraction zones for all three gradations exhibit an ellipsoidal shape in the vertical direction, with elliptical cross-sections. As the draw height increases, both the major and minor axes of the extraction zone’s maximum cross-section continuously enlarge, stabilizing beyond a draw height of 80 cm. The ore fragment size significantly influences the extraction zone dimensions. Gradation I, characterized by the smallest average particle size, yielded the largest extraction zone, whereas Gradation III, with the largest average particle size, resulted in the smallest. Numerical simulations of ore drawing for the different particle sizes were performed using PFC3D. The extent of the extraction zone in the numerical results was determined by reconstructing the initial positions of the drawn particles. The simulations show good agreement with the experimental findings, particularly regarding how the major and minor axes of the extraction zone cross-section vary with increasing draw height. Moreover, the simulations confirm that smaller average particle sizes enhance particle flowability, leading to larger extraction zones, as anticipated. Full article
(This article belongs to the Special Issue Mechanics, Damage Properties and Impacts of Coal Mining, 2nd Edition)
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16 pages, 4582 KB  
Article
Numerical Analysis of Electric Field in Oil-Immersed Current Transformer with Metallic Particles Inside Main Insulation
by Wei Lou, Bo Lu, Youxiang Pan, Zhou Han and Lujia Wang
Energies 2025, 18(14), 3628; https://doi.org/10.3390/en18143628 - 9 Jul 2025
Viewed by 378
Abstract
During the manufacturing process of oil-immersed current transformers, metallic particles may become embedded in the insulation wrapping, and the resulting electric field distortion is one of the primary causes of failure. Historically, the shape of metallic particles has often been simplified to a [...] Read more.
During the manufacturing process of oil-immersed current transformers, metallic particles may become embedded in the insulation wrapping, and the resulting electric field distortion is one of the primary causes of failure. Historically, the shape of metallic particles has often been simplified to a standard sphere, whereas in practice, these particles are predominantly irregular. In this study, ellipsoidal and flaky particles were selected to represent smooth and angular surfaces, respectively. Using COMSOL Multiphysics® (version 6.2) software, a three-dimensional simulation model of an oil-immersed inverted current transformer was developed, and the influence of defect position and size on electric field characteristics was analyzed. The results indicate that both types of defects cause electric field distortion, with longer particles exerting a greater influence on the electric field distribution. Under the voltage of a 220 kV system, elliptical particles (9 mm half shaft) lead to the maximum electric field intensity of main insulation of up to 45.1 × 106 V/m, while the maximum field strength of flaky particles (length 30 mm) is 28.9 × 106 V/m. Additionally, the closer the particles are to the inner side of the main insulation, the more significant their influence on the electric field distribution becomes. The findings provide a foundation for fault analysis and propagation studies related to the main insulation of current transformers. Full article
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13 pages, 1222 KB  
Article
Starch Digestion Characteristics of Different Starch Sources and Their Effects on Goslings’ Apparent Nutrient Utilization
by Zhi Yang, Jun Lin, Chen Xu, Xiyuan Xing, Haiming Yang and Zhiyue Wang
Vet. Sci. 2025, 12(7), 630; https://doi.org/10.3390/vetsci12070630 - 1 Jul 2025
Viewed by 747
Abstract
This study used integrated in vitro and in vivo approaches to investigate how the starch source (glutinous rice, indica rice, maize, or high-amylose rice) influences starch digestion kinetics and, consequently, the apparent nutrient utilization and amino acid metabolism in goslings. Four diets were [...] Read more.
This study used integrated in vitro and in vivo approaches to investigate how the starch source (glutinous rice, indica rice, maize, or high-amylose rice) influences starch digestion kinetics and, consequently, the apparent nutrient utilization and amino acid metabolism in goslings. Four diets were formulated using glutinous rice, indica rice, maize, and high-amylose rice, and in vitro digestion and animal experiments were carried out. The data showed the particle sizes of the four starches: glutinous rice ≈ indica rice < corn < amylose. The glutinous rice starch grain is a porous polyhedron with an angular surface, the corn starch grain is an ellipsoid with a smooth surface, the indica rice starch grain is a polyhedron with a smooth and compact surface, and the high-amylose starch grain is an irregular polyhedron with a smooth surface. Starch digestibility was relatively stable for the indica and corn-based diets, and starch digestibility was higher for the indica rice diet compared to the corn- and high-amylose starch-based diets. The utilization of Asp, Ser, Glu, Gly, and Phe was higher for the glutinous rice diet compared to the maize and high-amylose diets. Furthermore, with this diet, the availability of Thr and Ala was observed to be higher than with the indica rice and high-amylose diets. In conclusion, the particle size and structure of starch from different sources (glutinous rice, indica rice, corn, and high-amylose rice) were different, significantly affecting the starch digestion rate. The glutinous rice diet enables a fast digestion rate for starch, which is rapidly digested in the proximal intestine. The inadequate supply of glucose in the distal intestine enhances the oxidative energy supply from dietary amino acids in that region, thereby improving the apparent digestibility of both starch and crude protein. Full article
(This article belongs to the Section Veterinary Physiology, Pharmacology, and Toxicology)
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23 pages, 1053 KB  
Article
Inverse Gravimetric Problem Solving via Prolate Ellipsoidal Parameterization and Particle Swarm Optimization
by Ruben Escudero González, Zulima Fernández Muñiz, Antonio Bernardo Sánchez and Juan Luis Fernández Martínez
Mathematics 2025, 13(12), 2017; https://doi.org/10.3390/math13122017 - 18 Jun 2025
Viewed by 380
Abstract
We present a method for 3D gravity inversion using ellipsoidal parametrization and Particle Swarm Optimization (PSO), aimed at estimating the geometry, density contrast, and orientation of subsurface bodies from gravity anomaly data. The subsurface is modeled as a set of prolate ellipsoids whose [...] Read more.
We present a method for 3D gravity inversion using ellipsoidal parametrization and Particle Swarm Optimization (PSO), aimed at estimating the geometry, density contrast, and orientation of subsurface bodies from gravity anomaly data. The subsurface is modeled as a set of prolate ellipsoids whose parameters are optimized to minimize the misfit between observed and predicted anomalies. This approach enables efficient forward modeling with closed-form solutions and allows the incorporation of geometric and physical constraints. The algorithm is first validated on synthetic models with Gaussian noise, successfully recovering complex multi-body configurations with acceptable uncertainty. A statistical analysis based on multiple PSO runs provides interquartile ranges (IQRs) to quantify inversion stability. The method is then applied to a real microgravity dataset from the Nirano Salse mud volcanoes (northern Italy) using a field acquisition strategy previously described in the literature. Unlike earlier studies based on commercial software, our inversion uses the ellipsoidal–PSO framework. The best-fitting model includes four ellipsoids (two low- and two high-density), reproducing the main features of the observed Bouguer anomaly with a prediction error of 20–25%. The inferred geometry suggests that fluid migration is controlled by fault-related damage zones rather than shallow reservoirs. This method is robust, interpretable, and applicable to both synthetic and real cases, with potential uses in geotechnical, volcanic, and hydrogeological studies. Full article
(This article belongs to the Special Issue Inverse Problems in Science and Engineering)
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38 pages, 39712 KB  
Article
Experimental and Simulative Investigation of Deterministic Lateral Displacement and Dielectrophoresis Methods for Continuous Multi-Property Particle Sorting
by Jonathan Kottmeier, Maike Sophie Wullenweber, Zhen Liu, Ingo Kampen, Arno Kwade and Andreas Dietzel
Powders 2025, 4(2), 13; https://doi.org/10.3390/powders4020013 - 13 May 2025
Cited by 1 | Viewed by 659
Abstract
Simulative and experimental studies were carried out to address multi-dimensional particle fractionation of non-biological particles according to size, shape, and density inside a high-throughput DLD array. Density sensitive separation was achieved for melamine and polystyrene particles at a diameter of 5 µm at [...] Read more.
Simulative and experimental studies were carried out to address multi-dimensional particle fractionation of non-biological particles according to size, shape, and density inside a high-throughput DLD array. Density sensitive separation was achieved for melamine and polystyrene particles at a diameter of 5 µm at a Reynolds number (Re) of 82, corresponding to an overall flow rate of 11.3 mL/min. This process is very sensitive, as no fractionation occurred for Re = 85 (11.7 mL/min). For the first time, the fractionation of elliptical polystyrene particles (5 × 10 µm) at Re > 1 was investigated up to Re = 80 (11 mL/min). A separation of elliptical particles from spherical melamine particles (5 µm) was observed in single experiments at all investigated Reynolds numbers. However, the separation is not reliably repeatable due to partial clogging of ellipsoidal particles along the posts. In addition, higher concentrations of polydisperse silica suspensions were experimentally investigated by using polydisperse silica particles at concentrations up to 0.4% (m/V) up to Re = 80 (20 mL/min). The separation size generally decreased with increasing Reynolds number and increased with increasing concentration. Separation efficiency decreased with increasing concentration, independent of the Reynolds number. In order to investigate the material-dependent separation in a contactless dielectrophoresis system (cDEP), the resolved CFD-DEM software was extended to calculate dielectrophoretic forces on particles. With this, the second stage of a serial-combined DLD-DEP system was simulated, showing good separation at lower flow rates. For these systems, different fabrication methods to minimize the distance between the electrodes and the fluid as well as the requirement to withstand high-throughput applications, were investigated. Full article
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19 pages, 15975 KB  
Article
Utilization of Marine-Dredged Sediment and Calcium Sulfoaluminate Cement for Preparing Non-Sintered Ceramsites: Properties and Microstructure
by Jiuye Zhao, Zijian Wang, Mengying Xiao, Chunyi Cui and Hailong Liu
J. Mar. Sci. Eng. 2025, 13(5), 891; https://doi.org/10.3390/jmse13050891 - 30 Apr 2025
Viewed by 519
Abstract
The resource utilization of marine-dredged sediment is considered a sustainable approach to its disposal. This paper investigates the preparation of non-sintered ceramsites from marine-dredged sediments and CSA cement via cold-bonded pelletization. The study examines the effects of various preparation conditions on the engineering [...] Read more.
The resource utilization of marine-dredged sediment is considered a sustainable approach to its disposal. This paper investigates the preparation of non-sintered ceramsites from marine-dredged sediments and CSA cement via cold-bonded pelletization. The study examines the effects of various preparation conditions on the engineering properties, phase compositions and microstructures of non-sintered ceramsites. The results indicate that preparation conditions significantly influence the particle size distribution of non-sintered ceramsites. The early-strength development of non-sintered ceramsites prepared from CSA cement is remarkable, with the PCS achieving approximately 60% and 80% of the 28-day strength within 3 days and 7 days, respectively—a marked contrast to OPC. Response surface methodology analysis reveals significant interaction effects between the disc rotation angle, rotational speed, and duration of rotation on the PCS of non-sintered ceramsites. The open-ended porosity of non-sintered ceramsites exhibits greater sensitivity to changes in preparation parameters compared to closed-ended porosity and total porosity. The preparation conditions have negligible impact on the hydration process of CSA cement in non-sintered ceramsites. For both ellipsoidal and plate-like marine-dredged soil particles, ettringite and the AH3 phase provide effective pore-filling and binding effects in the microstructures of non-sintered ceramsites. These findings imply that low-carbon utilization of marine-dredged sediments through the preparation of non-sintered ceramsites offers a nature-based solution for sustainable management in coastal systems. Full article
(This article belongs to the Special Issue Nature-Based Solutions in Coastal Systems)
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22 pages, 5344 KB  
Article
Research on Calibration Method of Triaxial Magnetometer Based on Improved PSO-Ellipsoid Fitting Algorithm
by Jun Guan, Zhihui Chen and Guilin Jiang
Electronics 2025, 14(9), 1778; https://doi.org/10.3390/electronics14091778 - 27 Apr 2025
Cited by 1 | Viewed by 618
Abstract
To address the measurement accuracy degradation of triaxial magnetometers caused by manufacturing errors and environmental interference, and the limited robustness of traditional calibration methods, this study proposes a Dynamic Hierarchical Elite-guided Particle Swarm Optimization (DHEPSO)-based ellipsoid fitting algorithm. First, an error model for [...] Read more.
To address the measurement accuracy degradation of triaxial magnetometers caused by manufacturing errors and environmental interference, and the limited robustness of traditional calibration methods, this study proposes a Dynamic Hierarchical Elite-guided Particle Swarm Optimization (DHEPSO)-based ellipsoid fitting algorithm. First, an error model for the triaxial magnetometers is established. Next, the DHEPSO algorithm is utilized to fit the ellipsoid parameters by integrating a dynamic hierarchical mechanism, elite guidance strategy, and adaptive inertia weight adjustment, thereby balancing global exploration and local exploitation to efficiently optimize the parameters. Finally, error compensation and precise calibration are achieved using the optimized parameters. The simulation results show that, compared to the Least Squares Method (LSM), it reduces the absolute distance between the simulated data and the ellipsoid by 63.10% and the post-calibration total magnetic field intensity standard deviation by 60% under outlier interference. Against the traditional PSO, TSLPSO, MPSO, and AWPSO, DHEPSO achieves total distance reductions of 48.52%, 47.74%, 56.71%, and 33.09%, respectively, with faster convergence. The statistical analysis of 60 trials confirms DHEPSO’s stability, exhibiting lower median error and interquartile range. The results validate DHEPSO’s high precision and robustness in high-noise environments, offering theoretical support for engineering applications. Full article
(This article belongs to the Special Issue Advancements in Connected and Autonomous Vehicles)
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24 pages, 8639 KB  
Article
Investigation of the Impact of Particle Shape on Pore Structures and Clogging Properties of Filter Layers
by Wei-Kang Bai, Fa-Ning Dang, Wu-Wei Zhu, Yi Yao, Hai-Bin Xue and Jun Gao
Appl. Sci. 2025, 15(8), 4563; https://doi.org/10.3390/app15084563 - 21 Apr 2025
Viewed by 633
Abstract
This study posits that soil particles in the filter layer are ellipsoidal. The effective pore radius of the filter material was calculated for various particle-shape parameters and distributions. The relationship between the porosity of the filter material and the ratio of the long [...] Read more.
This study posits that soil particles in the filter layer are ellipsoidal. The effective pore radius of the filter material was calculated for various particle-shape parameters and distributions. The relationship between the porosity of the filter material and the ratio of the long axis to the short axis of ellipsoidal particles in a loose arrangement was also examined. The results indicate that the porosity of the filter material initially decreases and subsequently increases with increases in the ratio of the long axis to the short axis; however, the rate of increase progressively slows. A method for transforming irregularly shaped particles into ellipsoidal forms is proposed. The particle-shape parameter, S, is introduced to characterize the shape of irregular particles. The relationship between particle-shape parameters and the ratio of the long axis to the short axis was investigated specifically for ellipsoidal particles. It was found that the particle-shape parameters exhibit an approximately linear relationship with the ratio of the long axis to the short axis within a specific range. The discrete element method was employed to investigate the impact of particle shape on the filtration characteristics of the filter layer and was complemented by comparative experimental analysis. By analyzing the pore structures of spherical and ellipsoidal particles, this study predicts the relationship between pore structure and particle-shape parameters for any irregularly shaped natural-particle filter layer. Full article
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20 pages, 8522 KB  
Article
CFD-DEM Modeling and Experimental Verification of Heat Transfer Behaviors of Cylindrical Biomass Particles with Super-Ellipsoid Model
by Yuhao Hu, Likuan Chen, Zihan Liu, Huaqing Ma, Lianyong Zhou and Yongzhi Zhao
Energies 2025, 18(6), 1504; https://doi.org/10.3390/en18061504 - 18 Mar 2025
Viewed by 679
Abstract
The heat transfer (HT) characteristics of cylindrical biomass particles (CBPs) in fluidized beds (FBs) are important for their drying, direct combustion, and thermochemical transformation. To provide a deeper insight into the complex mechanisms behind the HT behaviors involving CBPs, this study developed a [...] Read more.
The heat transfer (HT) characteristics of cylindrical biomass particles (CBPs) in fluidized beds (FBs) are important for their drying, direct combustion, and thermochemical transformation. To provide a deeper insight into the complex mechanisms behind the HT behaviors involving CBPs, this study developed a cylindrical particle HT model within the framework of computational fluid dynamics coupled with the discrete element method (CFD-DEM) in which the CBPs were characterized by the super-ellipsoid model, which has the unique merit of striking a balance between computational accuracy and efficiency. The newly developed heat transfer model considers particle–particle (P-P), particle–wall (P-W), and fluid–particle (F-P). Its accuracy was verified by comparing the numerical results with the experimental infrared thermography measurements in terms of the temperature evolution of the cylindrical particles. The effects of the gas velocity, inlet temperature, and thermal conductivity of particles on the HT behaviors of the CBPs were investigated comprehensively. The results demonstrated the following: (1) Gas velocity can improve the uniformity of bed temperature distribution and shorten the fluctuation process of bed temperature uniformity. (2) A 26.8% increase in inlet temperature leads to a 13.4% increase in the proportion of particles with an orientation in the range of 60–90°. (3) The thermal conductivity of particles has no obvious influence on the bed temperature, convective HT rate, or orientation of particles. Full article
(This article belongs to the Section J1: Heat and Mass Transfer)
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20 pages, 7166 KB  
Article
Drag Force and Heat Transfer Characteristics of Ellipsoidal Particles near the Wall
by Yongkang Yang, Xinyu Dong and Ting Xiong
Water 2025, 17(5), 736; https://doi.org/10.3390/w17050736 - 3 Mar 2025
Cited by 3 | Viewed by 1018
Abstract
This study investigates the force and heat transfer characteristics of oblate spheroidal particles in gas–solid two-phase flows near walls, addressing the influence of particle orientation, shape, Reynolds number, and particle–wall distance. These factors are critical in industrial processes such as pneumatic transport and [...] Read more.
This study investigates the force and heat transfer characteristics of oblate spheroidal particles in gas–solid two-phase flows near walls, addressing the influence of particle orientation, shape, Reynolds number, and particle–wall distance. These factors are critical in industrial processes such as pneumatic transport and crop drying, as well as in natural phenomena. Utilizing the Euler–Lagrangian model and large eddy simulation (LES), we simulated flow fields and heat transfer under various conditions. The results indicate that at Re = 500, turbulence mitigates wall interference, leading to a 14.4% increase in the Nusselt number (Nu). Particle orientation plays a crucial role in heat transfer, with Nu decreasing by 20% at = 90° due to restricted interstitial flow. A higher aspect ratio (Ar = 0.8) enhances heat transfer by 25% compared to a lower aspect ratio (Ar = 0.1). Additionally, increasing the particle–wall distance from H = 0.25dv to H = 0.5dv reduces wall-induced drag by 30%. The findings enhance the understanding of particle–fluid interactions near walls, providing a foundation for optimizing computational fluid dynamics models and improving industrial applications. Future work should consider additional variables such as particle roughness to further refine predictive capabilities. This study contributes to advancing theoretical and practical insights into non-spherical particle behaviors in complex flow environments. Full article
(This article belongs to the Section Hydraulics and Hydrodynamics)
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25 pages, 7530 KB  
Article
Establishment of a Discrete Element Model for Wheat Particles Based on the Ellipsoidal Method and CFD–DEM Coupling
by Boxuan Gu, Can Hu, Jianfei Xing, Xiaowei He, Xufeng Wang, Kai Ren and Long Wang
Agriculture 2025, 15(4), 369; https://doi.org/10.3390/agriculture15040369 - 10 Feb 2025
Cited by 2 | Viewed by 1019
Abstract
The precision of simulation plays a pivotal role in determining the design parameters of the pressure pipe and distributor in a pneumatic centralized seeding system. This study adopted the discrete element method (DEM) to investigate wheat seed models and their motion characteristics within [...] Read more.
The precision of simulation plays a pivotal role in determining the design parameters of the pressure pipe and distributor in a pneumatic centralized seeding system. This study adopted the discrete element method (DEM) to investigate wheat seed models and their motion characteristics within a pneumatic precision seed-metering device. Using Xinchun No. 6 wheat as the experimental subject, multi-sphere combination models (5, 7, 9, and 11 balls) were employed to describe the seed particle morphology. Moreover, by utilizing the coupling method of the Discrete Element Method (DEM) and Computational Fluid Dynamics (CFD), along with bench tests, the air suspension velocity of seeds and the motion characteristics of the seed-supplying device were analyzed under different particle models. The physical properties of the wheat seeds were measured during the experiments. The simulation results indicated that, as the seed supply rate increased, the airflow velocity distribution within the model became more uniform, enhancing the stability of the suspension velocity. Comparisons between experiments and simulations validated the reliability of the particle models, with the minimum relative error in the suspension velocity determined as 0.21% for the 9-balls model. In addition, compared to the other models, the 9- and 5-balls models more accurately simulated the dynamic behavior of seeds within the seed-supplying device. For the 9-balls model, the relative error of particle velocity in the seed-supplying device is 1.39%, and, in the simulation of displacements in the X and Y directions of the seed-supplying device, the average error is 9.51%. The effectiveness of the multi-sphere combination models was verified, indicating their ability to accurately reflect the dynamic behavior of wheat seeds and improve the design and optimization efficiency of pneumatic precision seed-metering devices. Full article
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25 pages, 3504 KB  
Article
The Distributions and Dependences of 3D Particle Morphology Characteristics for Crushed and Natural Sands by X-Ray uCT Investigations
by Hao Yang, Xu Li, Junhui Zhang, Zhengbo Hu and Shengnan Li
Materials 2024, 17(23), 5805; https://doi.org/10.3390/ma17235805 - 27 Nov 2024
Cited by 1 | Viewed by 849
Abstract
The morphology of an individual particulate refers to its shape characteristics and size properties, which both play important roles for granular matter in physics, mechanics, chemistry, and biology. In this study, ellipsoidality is defined as a 3D shape index for evaluating particle roundness, [...] Read more.
The morphology of an individual particulate refers to its shape characteristics and size properties, which both play important roles for granular matter in physics, mechanics, chemistry, and biology. In this study, ellipsoidality is defined as a 3D shape index for evaluating particle roundness, and an explicit calculation method is applied. The dependences of 3D shape characteristics (aspect ratios, sphericity, and ellipsoidal degree) on particle size (ranges from 0.063 mm to 5.0 mm) are adequately investigated with the X-ray micro-computed microtomography (uCT) imaging for hundreds of thousands of particles of crushed and natural sands. This study focuses on comparing and evaluating the specific surface area and equivalent diameter, suggesting that particle segregation and changes in surface area may explain the strong dependence of particle shape on size. The correlation between different shape metrics was analyzed by comparing crushed sand with natural sand to provide theoretical support for material filling and mechanical behaviour. The significant differences in the microscale particle size indexes of different sands by single grading are used to provide data references for further analyses of the effect of material microscale on material properties in future discrete element particle simulations. Full article
(This article belongs to the Section Construction and Building Materials)
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15 pages, 5231 KB  
Article
Elongated Particles Show a Preferential Uptake in Invasive Cancer Cells
by Talya Cohen, Chalom Zemmour, Ora T. Cohen and Ofra Benny
Nanomaterials 2024, 14(23), 1891; https://doi.org/10.3390/nano14231891 - 25 Nov 2024
Cited by 1 | Viewed by 1599
Abstract
Mechanically driven cellular preference for drug carriers can enhance selectivity in cancer therapy, underscoring the importance of understanding the physical aspects of particle uptake. In this study, it was hypothesized that elongated particles might be preferentially taken up by deformable, aggressive cancer cells [...] Read more.
Mechanically driven cellular preference for drug carriers can enhance selectivity in cancer therapy, underscoring the importance of understanding the physical aspects of particle uptake. In this study, it was hypothesized that elongated particles might be preferentially taken up by deformable, aggressive cancer cells compared to normal cells. Two film-stretching methods were tested for 0.8–2.4 μm polystyrene (PS) particles: one based on solubility in organic solvents and the other on heat-induced softening. The heat-induced method produced more homogenous particle batches, with a standard deviation in the particle aspect ratio of 0.42 compared to 0.91 in the solvent-based method. The ability of cells to engulf elongated PS particles versus spherical particles was assessed in two subsets of human melanoma A375 cells. In the more aggressive cancer cell subset (A375+), uptake of elongated PS particles increased by 10% compared to spherical particles. In contrast, the less aggressive subset (A375−) showed a 25% decrease in uptake of elongated particles. This resulted in an uptake ratio between A375+ and A375− that was 1.5 times higher for elongated PS particles than for spherical ones. To further demonstrate relevance to drug delivery, elongated paclitaxel-loaded biodegradable, slow-releasing poly(lactic-co-glycolic) acid (PLGA) particles were synthesized. No significant difference in cytotoxic effect was observed between A375+ and A375− cells treated with spherical drug-loaded particles. However, treatment with ellipsoidal particles led to a significantly enhanced cytotoxic effect in aggressive cells compared to less aggressive cells. These findings present promising directions for tailored cancer drug delivery and demonstrate the importance of particle physical properties in cellular uptake and drug delivery mechanisms. Full article
(This article belongs to the Special Issue Synthesis and Applications of Anisotropic Nanoparticles)
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23 pages, 16573 KB  
Article
The Effect of Ellipsoidal Particle Surface Roughness on Drag and Heat Transfer Coefficients Using Particle-Resolved Direct Numerical Simulation
by Heng Luo, Fengbin Zhang, Haibo Huang, Yong Huang, Zhendong Liu, Jianxi Yan and Chicheng Yang
Processes 2024, 12(11), 2473; https://doi.org/10.3390/pr12112473 - 7 Nov 2024
Viewed by 1292
Abstract
The purpose of this study is to estimate the effect of roughness layer thickness on the heat transfer and drag coefficients of ellipsoidal particles. Using an OpenFOAM-based particle-resolved direct numerical simulation (PR-DNS) method, we calculated the drag coefficient and Nusselt number for an [...] Read more.
The purpose of this study is to estimate the effect of roughness layer thickness on the heat transfer and drag coefficients of ellipsoidal particles. Using an OpenFOAM-based particle-resolved direct numerical simulation (PR-DNS) method, we calculated the drag coefficient and Nusselt number for an isolated axisymmetric nonspherical particle with a rough surface in a uniform flow. The PR-DNS results indicate that the drag coefficient varies linearly with the effective roughness Sef at different angles, which can be expressed as CD=kSef1+CD0. The changes in k are consistent with the Happel and Brenner equation. Furthermore, the influence of roughness on the heat transfer efficiency factor can be represented by Ef=Sef65. The models for the drag coefficient and Nusselt number are valid within the ranges 1.25Ar2.5,1Sef2, and 10Rep200, thereby extending the applicability of the equations developed for smooth particles. These newly developed correlations for the drag coefficient and Nusselt number can be utilized for non-isothermal flows of particle mixtures containing materials with various rough-surfaced ellipsoids. Full article
(This article belongs to the Section Materials Processes)
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