Search Results (184)

Mean flow velocities and the corresponding turbulence fluctuation velocities were measured within the suction port of a standard twin-screw compressor using LDV and PIV optical techniques. Time-resolved velocity measurements were carried out over a time window of 1° at a rotor speed of 1000 rpm, a pressure ratio of 1, and an air temperature of 55 °C. Detailed LDV measurements revealed a very stable and slow inflow, with almost no influence from rotor movements except near the rotors, where a more complex flow formed in the suction port. The axial velocity near the rotors exhibited wavy profiles, while the horizontal velocity showed a rotational flow motion around the centre of the port. The turbulence results showed uniform distributions and were independent of the rotors’ motion, even near the rotors. PIV measurements confirmed that there is no rotor movement influence on the inflow structure and revealed complex flow structures, with a crossflow dominated by a main flow stream and two counter-rotating vortices in the X-Y plane; in the Y-Z plane, the presence of a strong horizonal stream was observed away from the suction port, which turned downward vertically near the entrance of the port. The corresponding turbulence results in both planes showed uniform distributions independent of rotor motions that were similar in all directions. Full article

This paper presents a study aiming to provide insight into the complex flow and heat transfer processes in the exhaust manifold of a four-stroke, compression ignition engine. An experimental system has been constructed capable of capturing temperature and heat flux high-frequency signals as they develop in the exhaust pipe wall during the engine cycle, under its steady-state operation. The values of the Heat Transfer Coefficient obtained by applying the classic convection relations have been correlated in the form of a Nusselt–Reynolds number relationship for local and spatially averaged steady-state heat transfer and compared with available experimental data obtained at the same position of the exhaust manifold. It has been shown that the use of conventional steady-state heat transfer relationships for fully developed steady-state turbulent flow in pipes underpredicts heat transfer rates when compared with those experimentally observed. Periodic flow of high frequency and geometrical effects at the exhaust entrance are expected to affect the validity of the application of the classic steady-state correlations for the exhaust manifold. To overcome this problem it is developed and presented a new correlation for the time-averaged heat transfer rates. To verify the heat transfer mechanism, the thermal field of the whole engine cylinder head, including the intake and exhaust manifolds, was analyzed using FEA (Finite Element Analysis), and the results are compared and verified with available experimental data. Full article

Enzymatic CO₂ fixation offers great potential for the sustainable synthesis of value-added compounds. Malic enzyme (ME) catalyzes the reverse carboxylation of pyruvate to malate, enabling direct CO₂ conversion into C₄ compounds with broad biosynthetic applications. However, the reverse carboxylation activity of wild-type ME is insufficient, and conventional enzyme engineering strategies remain limited by the complexity of identifying distal functional sites. Here, we present a Structure–Sequence–SCANNER (3S) co-evolution strategy that integrates protein structural analysis, sequence conservation profiling, and co-evolutionary network analysis to enable systematic identification of functionally relevant hotspot residues. Using this approach, we engineered Escherichia coli ME (EcME) variants with enhanced CO₂ fixation activities. In total, 106 single-point variants were constructed and screened. Among these, variants A464S and D97E exhibited significantly improved reverse carboxylation activities, with 1.7-fold and 1.6-fold increases in catalytic activity and 1.5-fold and 1.8-fold improvements in catalytic efficiency (k_cat/K_m), respectively, compared to wild-type EcME. Their catalytic efficiencies (k_cat/K_m) improved by 1.5-fold and 1.8-fold, increasing from 80 mM⁻¹·min⁻¹ for the wild-type enzyme to 120 and 130 mM⁻¹·min⁻¹, respectively. Mechanistic analyses revealed that A464S introduces a stabilizing hydrogen bond with N462, enhancing NADPH binding, while D97E forms a new salt bridge network with K513, resulting in contraction of the substrate pocket entrance and increased pyruvate affinity. These findings demonstrate the effectiveness of the 3S strategy in reprogramming enzyme functions and highlight its potential for constructing efficient artificial CO₂ fixation systems. Full article

Millisecond lasers, with their high processing efficiency and large power, are widely used in manufacturing fields such as aerospace. This study aims to investigate the effects of different processing parameters on the micro-hole processing of 316 heat-resistant steel using millisecond lasers. Through the control variable method, the study examines the impact of pulse energy, pulse count, and pulse width on the quality of micro-holes, including the entrance diameter, exit diameter, and taper. Furthermore, combined with orthogonal experiments and COMSOL Multiphysics 6.2 simulations, the study explores the influence of pulse width on the formation of blind holes. The experimental results show that when the pulse energy is 2.2 J, the taper is minimal (2.2°), while the taper reaches its peak (2.4°) at 2.4 J pulse energy. As the pulse count increases to 55–60 pulses, the exit diameter stabilizes, and the taper decreases to 1.8°. Blind holes begin to form when the pulse width exceeds 1.2 ms. When the pulse width is 1.2 ms, pulse energy is 2.4 J, and pulse count is 50, the entrance diameter of the blind hole reaches its maximum, indicating that longer pulse widths result in more significant energy reflection and thermal accumulation effects. COMSOL simulations reveal that high-energy pulses cause intense melt ejection, while longer pulse widths exacerbate thermal accumulation at the micro-hole entrance, leading to blind hole formation. This study provides important process references for laser processing of through-holes and blind holes in heat-resistant steel. Full article

The model explicitly incorporates boundary conditions that account for the complex interplay between sections experiencing varying degrees of reduction. This interaction significantly influences the overall deformation behavior and force loading. The control effect is associated with boundary conditions determined by the unevenness of the compression, which have certain quantitative and qualitative characteristics. These include additional loading, which is less than the main load, which implements the process of plastic deformation, and the ratio of control loads from the entrance and exit of the deformation site. According to this criterion, it follows from experimental data that the controlling effect on the plastic deformation site occurs with a ratio of additional and main loading in the range of 0.2–0.8. The next criterion is the coefficient of support, which determines the area of asymmetry of the force load and is in the range of 2.00–4.155. Furthermore, the criterion of the regulating force ratio at the boundaries of the deformation center forming a longitudinal plastic shear is within the limits of 2.2–2.5 forces and 1.3–1.4 moments of these forces. In this state, stresses and deformations of the plastic medium are able to realize the effects of plastic shaping. The force effect reduces with an increase in the unevenness of the deformation. This is due to a change in height of the longitudinal interaction of the disparate sections of the strip. There is an appearance of a new quality of loading—longitudinal plastic shear along the deformation site. The unbalanced additional force action at the entrance of the deformation source is balanced by the force source of deformation, determined by the appearance of a functional shift in the model of the stress state of the metal. The developed theory, using the generalized method of an argument of functions of a complex variable, allows us to characterize the functional shift in the deformation site using invariant Cauchy–Riemann relations and Laplace differential equations. Furthermore, the model allows for the investigation of material properties such as the yield strength and strain hardening, influencing the size and characteristics of the identified limit state zone. Future research will focus on extending the model to incorporate more complex material behaviors, including viscoelastic effects, and to account for dynamic loading conditions, more accurately reflecting real-world milling processes. The detailed understanding gained from this model offers significant potential for optimizing mill roll designs and processes for enhanced efficiency and reduced energy consumption. Full article

In this study, we examined the microclimates at eight entrances to a karst system distributed between an elevation of 812 and 906 m in Southern Spain. The karst system, characterised by subvertical open tectonic joints that form narrow shafts, developed on the slope of a mountainous area with a Mediterranean climate and strong chimney effect, resulting in an intense airflow throughout the year. The airflows modify the entrance temperatures, creating a distinctive pattern in each opening that changes with the seasons. The objective of this work is to characterise the outflows and find simple temperature-based parameters that provide information about the karst interior. The entrances were monitored for five years (2017–2022) with temperature–humidity dataloggers at different depths. Other data collected include discrete wind measurements and outside weather data. The most significant parameters identified were the characteristic temperature (T_y), recorded at the end of the outflow season, and the rate of cooling/warming, which ranges between 0.1 and 0.9 °C/month. These parameters allowed the entrances to be grouped based on the efficiency of heat exchange between the outside air and the cave walls, which depends on the rock-boundary geometry. This research demonstrates that simple temperature studies with data recorded at selected positions will allow us to understand geometric aspects of inaccessible karst systems. Dynamic high-airflow cave systems could become a natural source of evidence for climate change and its effects on the underground world. Full article

As urbanization has accelerated, rail transit has evolved from being a mere means of transportation to a public area that houses the city’s cultural memory and serves as a crucial portal for the public to understand the culture of the city. As an urban public space with huge passenger flow, the metro (or subway) cultural space has also become a public cultural space, serving communal welfare and representing the image of the city. It is currently attracting more and more attention from the academic community. Wuhan, located in central China, has many subway lines and its engineering construction has set several national firsts, which is a typical sample of urban subway development in China. In this study, we use Python 3.13.0 crawler technology to capture the public’s comments on cultural space of Wuhan metro in social media and adopt SnowNLP sentiment score and LDA thematic clustering analysis to explore the overall quality, distinct characteristics, and deficiencies of Wuhan metro cultural space construction, and propose targeted design optimization strategies based on this study. The main findings are as follows: (1) The metro cultural space is an important window for the public to perceive the city culture, and the public in general shows positive perception of emotions: among the 16,316 data samples, 47.7% are positive comments, 17.8% are neutral comments, and 34.5% are negative comments. (2) Based on the frequency of content in the sample data for metro station exit and entrance space, metro train space, metro concourse and platform space, they are ranked as weak cultural spaces (18%), medium cultural spaces (33%), and strong cultural spaces (49%) in terms of the public’s perception of urban culture. (3) At present, there are certain deficiencies in Wuhan metro cultural space: the circulation paths in concourses and platforms are overly dominant, leaving little space for rest or interaction; the cultural symbols of metro train space are fragmented; the way of articulation between cultural and functional space in the metro station exit and entrance space is weak, and the space is single in form. (4) Wuhan metro cultural space needs to be based on locality landscape expression, functional zoning reorganization, innovative scene creation to optimize the visual symbol system and behavioral symbol system in the space, to establish a good image of the space, and to strengthen the public’s cultural identity and emotional resonance. Full article

Cytochromes P450 (CYPs) form one of the largest enzyme superfamilies, with similar structural folds yet biological functions varying from synthesis of physiologically essential compounds to metabolism of myriad xenobiotics. Sterol 14α-demethylases (CYP51s) represent a very special P450 family, regarded as a possible evolutionary progenitor for all currently existing P450s. In metazoans CYP51 is critical for the biosynthesis of sterols including cholesterol. Here we determined the crystal structures of ligand-free CYP51s from the abyssal fish Coryphaenoides armatus and human-. Comparative sequence–structure–function analysis revealed specific structural elements that imply elevated conformational flexibility, uncovering a molecular basis for faster catalytic rates, lower substrate selectivity, and intrinsic resistance to inhibition. In addition, the C. armatus structure displayed a large-scale repositioning of structural segments that, in vivo, are immersed in the endoplasmic reticulum membrane and border the substrate entrance (the FG arm, >20 Å, and the β4 hairpin, >15 Å). The structural distinction of C. armatus CYP51, which is the first structurally characterized deep sea P450, suggests stronger involvement of the membrane environment in regulation of the enzyme function. We interpret this as a co-adaptation of the membrane protein structure with membrane lipid composition during evolutionary incursion to life in the deep sea. Full article

Midlatitude westerly and East Asian summer monsoon (EASM) are crucial circulation systems in the upper and lower troposphere of East Asia that significantly influence mid-summer precipitation pattern. However, their synergistic effect on mid-summer precipitation in North China (NC) remains unclear. In this study, the concurrent variations of mid-summer westerly and EASM are categorized into two configurations: strong westerly–strong EASM (SS) and weak westerly–weak EASM (WW). At the synoptic timescale, the SS configuration significantly enhances precipitation in NC, whereas the WW configuration suppresses mid-summer rainfall. The underlying mechanism is that the SS pattern stimulates an anomalous quasi-barotropic cyclone–anticyclone pair over the Mongolian Plateau–Yellow Sea region. Two anomalous water vapor channels (westerly-driven and EASM-driven water vapor transport) are established in the southern and western peripheries of this cyclone–anticyclone pair, ensuring abundant moisture supply over NC. Meanwhile, frequently occurring westerly jet cores in northern NC form a jet entrance region, favoring strong upper-level divergent pumping and deep accents in its southern flank. This synergy between strong westerlies and EASM enhances both the moisture transports and ascending movements, thereby increasing precipitation over NC. Conversely, the atmospheric circulation associated with the WW pattern exhibits opposite characteristics, resulting in decreased NC rainfall. Our findings elucidate the synoptic-scale influences of westerly–monsoon synergy on mid-summer rainfall, through regulating moisture transports and westerly jet-induced dynamic uplift, potentially improving predictive capabilities for mid-summer precipitation forecasting. Full article

The traditional residential courtyards in Xiaoyi Ancient City, Shanxi, are a typical architectural form demonstrating significant energy efficiency and climate adaptability. This research examines the climate adaptability of the traditional residential courtyards in Xiaoyi by conducting field measurements and quantitative analysis, and it suggests appropriate optimization strategies. The study concludes that the thermal comfort of the building can be significantly improved by the following factors: a south-facing orientation, central positioning of the inverted house, an enclosure degree of 0.85, a distance of 2400 mm between the main house and side house, a T-shaped courtyard proportions of 3:1, a linear courtyard proportions of 5:1, a U-shaped courtyard proportions of 3:1, an entrance porch proportions of 1.5:1, a gray space scale of 1200 mm under the main house eaves, 500 mm under the side house eaves, and window-to-wall proportion of 0.33 for the main house and 0.32 for the side house. This optimization not only enhances the energy efficiency of the building but also improves internal comfort, as it is based on climate-responsive design. In terms of the inheritance of traditional architectural wisdom and its modern application, this study emphasizes the significance of considering the climatic environment in building design, providing a theoretical foundation for renovating traditional residential and modern architectural design. Full article

In the high-temperature cooking process of Chinese-style catering, the oil fume accumulates on the inner wall of the flue during the cooling process, forming grease stains, which can easily trigger flue fires and cause a kitchen fire. Statistics indicate flue fires are a primary cause of kitchen fires in China. The changes in the composition of grease stains are due to different freezing points, which will adhere to different parts of the flue and be repeatedly heated and cooled if not cleaned in time. This leads to changes in combustion performance, subsequently affecting the progression of flue fire propagation. This paper takes grease deposits with different deposition times and locations in the flue of commercial kitchens as the research object. The research selected a medium-sized commercial kitchen flue (kitchen chimney) in Langfang City, with deposition times of the parts of the inlet and outlet for 2 months and grease in the inlet for a deposition time of 7 days, 60 days, and more than 1 year. This paper analyzed the grease deposits at different deposition positions at the flue inlet and outlet using a thermogravimetric analyzer and a gas-mass spectrometer. It is found that the primary components of the grease at the outlet have low molecular weight, thermal decomposition starting temperature ignition temperature, and activation energy in the first stage and will catch fire first; the grease at the inlet has a high comprehensive combustion performance, and the combustion is violent with little effect from the oxygen supply. Then, the pyrolysis analysis of grease stains located at the entrance of the flue is performed at different deposition times under air and nitrogen atmosphere. The results showed that the pyrolysis process of grease stains with a more than 1 year deposition time consists of two stages. One stage is the first weightlessness stage, which has the lowest activation energy, the longest combustion process, and the greatest fire risk; the other is the pyrolysis combustion process of grease stains with a deposition time of 7 days. Its activation energy is the highest, and the fire risk is the smallest. The research results can be a reference for the setting of the fire dampers and the cleaning time for the flue. Full article

Xishu Gardens, an exemplary narrative of classical Chinese gardens, faces challenges in preserving its commemorative spatial structures while accommodating modern visitors’ needs. While trajectory analysis is critical, existing studies struggle to interpret multi-dimensional perception-preference data owing to spatiotemporal mismatches in multi-source datasets. This study adopted an improved Ward–K-medoids hybrid clustering algorithm to analyze 885 trajectory samples and 34,384 synchronized data points capturing emotional valence, cognitive evaluations, and dwell time behaviors via panoramic digital twins across three heritage sites (Du Fu Thatched Cottage, San Su Shrine, and Wangjiang Tower Park). Our key findings include the following: (1) Axial bimodal patterns: Type I high-frequency looping paths (27.6–68.9% recurrence) drive deep exploration, in contrast to Type II linear routes (≤0.5% recurrence), which enable intensive node coverage. (2) Layout-perception dynamics: single-axis layouts maximize behavioral engagement (DFTC), free-form designs achieve optimal emotional-cognitive integration (WTP), and multi-axis systems amplify emotional-cognitive fluctuations (SSS). (3) Spatial preference hierarchy: entrance and waterfront zones demonstrate dwell times 20% longer than site averages. Accordingly, the proposed model synchronizes Type II peak-hour throughput with Type I off-peak experiential depth using dynamic path allocation algorithms. This study underscores the strong spatial guidance mechanisms of Xishu Gardens, supporting tourism management and heritage conservation. Full article

Siltation around the harbour entrance poses significant challenges to the navigational safety and operational stability of coastal ports. Previous research has predominantly focused on sedimentation mechanisms in sandy coastal environments, while studies on silt-muddy coasts remain scarce. This paper investigates the causes of siltation around the entrance of Binhai Port in Jiangsu Province, China, utilising field observation data and a two-dimensional tidal current numerical model, with emphasis on hydrodynamic variations and sediment dynamics. Observations reveal that tidal currents induce sediment deposition in the outer harbour entrance area, whereas pronounced scouring occurs near breakwater heads. During extreme weather events, such as Typhoons Lekima (2019) and Muifa (2022), combined wind–wave interactions markedly intensified sediment transport and accumulation, particularly amplifying siltation at the entrance, with deposition thicknesses reaching 0.5 m and 1.0 m, respectively. The study elucidates erosion–deposition patterns under combined tidal, wave, and wind forces, identifying two critical mechanisms: (1) net sediment transport directionality driven by tidal asymmetry, and (2) a lagged dynamic sedimentary response during sediment migration. Notably, the entrance zone, functioning as a critical conduit for water– sediment exchange, exhibits the highest siltation levels, forming a key bottleneck for navigational capacity. The insights gleaned from this study are instrumental in understanding the morphodynamic processes triggered by artificial structures in silt-muddy coastal systems, thereby providing a valuable reference point for the sustainable planning and management of ports. Full article

The paper intends to contribute to readers’ comprehension of the Greek telecommunications market, focusing on the strategic decisions associated with network tower-sharing analysis in Greece. The Greek telecommunications industry is described for the first time following the Structure–Conduct–Performance (SCP) paradigm of Industrial Organisation (IO), as a methodological tool of analysis. In that respect, an SCP model in its extended form is constructed, aiming to examine how structure, conduct, and performance interrelate to each other. More precisely, the SCP model explains how strategic decisions regarding tower infrastructure sharing between 2013–2022 were developed, as a result of a series of interactions and feedback effects, amongst market structure, operators’ conducts, and performances, resulting in strengthening competition and reshaping market structure with the entrance of a new player in the Greek mobile market, an independent TowerCo (Athens, Greece) in Greece. International tendencies and competition issues influencing domestic growth potentialities and alternative operators’ concentration will be addressed, too. The paper concludes with presenting a basically qualitative, explanatory interpretive analysis of the perspectives of network tower-sharing analysis in the Greek telecommunication industry, including policy recommendations for the near future and thoughts on future research, as well. Full article

The benzimidazole core (BI) plays a central role in biologically active molecules. The BI nucleus is widely used as a building block to generate a variety of bioactive heterocyclic compounds to be used as antihelmintics, antiprotozoal, antimalarials, anti-inflammatories, antivirals, antimicrobials, antiparasitics, and antimycobacterials. A versatile BI derivative is the 2-guanidinobenzimidazole (2GBI), which, together with its derivatives, is a very interesting poly-functional planar molecule having a delocalised 10 π electrons system conjugated with the guanidine group. The 2GBI molecule has five nitrogen atoms containing five labile N–H bonds, which interact with the out-ward-facing channel entrance, forming a labile complex with the biological receptor sites. In this work, 2GBI and their derivatives were analyzed as ligands to form host–guest, coordination and organometallic complexes. Synthesis methodology, metal geometries, hydrogen bonding (HB) interactions, and the biological activities of the complexes were discussed. Full article