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1,776 Results Found

  • Article
  • Open Access
11 Citations
4,438 Views
13 Pages

8 January 2020

Asynchronous brain–computer interfaces (BCIs) based on electroencephalography (EEG) generally suffer from poor performance in terms of classification accuracy and false-positive rate (FPR). Thus, BCI toggle switches based on electrooculogram (E...

  • Article
  • Open Access
11 Citations
2,699 Views
10 Pages

Development of a Deep-Learning Algorithm for Small Bowel-Lesion Detection and a Study of the Improvement in the False-Positive Rate

  • Naoki Hosoe,
  • Tomofumi Horie,
  • Anna Tojo,
  • Hinako Sakurai,
  • Yukie Hayashi,
  • Kenji Jose-Luis Limpias Kamiya,
  • Tomohisa Sujino,
  • Kaoru Takabayashi,
  • Haruhiko Ogata and
  • Takanori Kanai

26 June 2022

Deep learning has recently been gaining attention as a promising technology to improve the identification of lesions, and deep-learning algorithms for lesion detection have been actively developed in small-bowel capsule endoscopy (SBCE). We developed...

  • Article
  • Open Access
11 Citations
2,442 Views
16 Pages

A Zero False Positive Rate of IDS Based on Swin Transformer for Hybrid Automotive In-Vehicle Networks

  • Shanshan Wang,
  • Hainan Zhou,
  • Haihang Zhao,
  • Yi Wang,
  • Anyu Cheng and
  • Jin Wu

Software-defined vehicles (SDVs) make automotive systems more intelligent and adaptable, and this transformation relies on hybrid automotive in-vehicle networks that refer to multiple protocols using automotive Ethernet (AE) or a controller area netw...

  • Article
  • Open Access
256 Views
11 Pages

Optimal Timing for Neonatal Hearing Screening in Well-Babies

  • Lisanne Vonk,
  • Paula van Dommelen,
  • Iris Eekhout,
  • Noëlle N. Uilenburg,
  • Paul H. Verkerk and
  • Catharina (Kitty) P. B. van der Ploeg

In The Netherlands, preventive child healthcare (PCHC) has been carrying out neonatal hearing screening in well-babies since 2006. The aim of this study was to examine the relationship between the age of newborns and the false positive referral rate...

  • Brief Report
  • Open Access
8 Citations
3,693 Views
4 Pages

23 September 2020

The number of COVID-19 patients in Japan is considered low, compared with U.S. and European countries. However, recent serological survey reported that several percent of population showed IgG positive to SARS-CoV-2. Specificity in the assays might i...

  • Article
  • Open Access
3 Citations
3,211 Views
12 Pages

20 August 2023

In software development, early defect detection using static analysis can be performed without executing the source code. However, defects are detected on a non-execution basis, thus resulting in a higher ratio of false positives. Recently, studies h...

  • Article
  • Open Access
23 Citations
4,404 Views
12 Pages

The Combined Impact of CLIR Post-Analytical Tools and Second Tier Testing on the Performance of Newborn Screening for Disorders of Propionate, Methionine, and Cobalamin Metabolism

  • Dimitar K. Gavrilov,
  • Amy L. Piazza,
  • Gisele Pino,
  • Coleman Turgeon,
  • Dietrich Matern,
  • Devin Oglesbee,
  • Kimiyo Raymond,
  • Silvia Tortorelli and
  • Piero Rinaldo

The expansion of the recommend uniform screening panel to include more than 50 primary and secondary target conditions has resulted in a substantial increase of false positive results. As an alternative to subjective manipulation of cutoff values and...

  • Article
  • Open Access
15 Citations
6,191 Views
24 Pages

A Multiple Target Positioning and Tracking System Behind Brick-Concrete Walls Using Multiple Monostatic IR-UWB Radars

  • Sungwon Yoo,
  • Dingyang Wang,
  • Dong-Min Seol,
  • Chulsoo Lee,
  • Sungmoon Chung and
  • Sung Ho Cho

18 September 2019

Recognizing and tracking the targets located behind walls through impulse radio ultra-wideband (IR-UWB) radar provides a significant advantage, as the characteristics of the IR-UWB radar signal enable it to penetrate obstacles. In this study, we desi...

  • Article
  • Open Access
10 Citations
4,791 Views
9 Pages

Newborn Screening for Krabbe Disease: Status Quo and Recommendations for Improvements

  • Dietrich Matern,
  • Khaja Basheeruddin,
  • Tracy L. Klug,
  • Gwendolyn McKee,
  • Patricia U. Edge,
  • Patricia L. Hall,
  • Joanne Kurtzberg and
  • Joseph J. Orsini

Krabbe disease (KD) is part of newborn screening (NBS) in 11 states with at least one additional state preparing to screen. In July 2021, KD was re-nominated for addition to the federal Recommended Uniform Screening Panel (RUSP) in the USA with a two...

  • Article
  • Open Access
692 Views
28 Pages

14 December 2025

This article addresses anomaly detection in multichannel spatiotemporal data under strict low-false-alarm constraints (e.g., 1% False Positive Rate, FPR), a requirement essential for safety-critical applications such as signal interference monitoring...

  • Article
  • Open Access
2 Citations
3,638 Views
16 Pages

5 September 2021

The Amery Ice Shelf (AIS) dynamics and mass balance caused by iceberg calving and basal melting are significant in the ocean climate system. Using satellite imagery from Sentinel-1 SAR, we monitored the temporal and spatial variability of the frontal...

  • Article
  • Open Access
3 Citations
3,411 Views
16 Pages

The adolescent depressive prodrome has been conceptualized as an early integrated sign of depressive symptoms, which may develop to a first episode of depression or return to normal for the adolescents. In this study, depressive prodrome presented th...

  • Article
  • Open Access
3 Citations
4,184 Views
14 Pages

Pro- and Anti-Angiogenic Markers as Clinical Tools for Suspected Preeclampsia with and without FGR near Delivery—A Secondary Analysis

  • Kristina Kumer,
  • Adi Sharabi-Nov,
  • Vesna Fabjan Vodušek,
  • Tanja Premru Sršen,
  • Nataša Tul,
  • Teja Fabjan,
  • Hamutal Meiri,
  • Kypros Herodotos Nicolaides and
  • Joško Osredkar

8 February 2021

Objective—the objective of this study was to assess the accuracy of placental growth factor (PlGF), soluble Fms-like Tyrosine Kinase 1 (sFlt-1), and endoglin (sEng) in the diagnosis of suspected preeclampsia (PE) with and without fetal growth restric...

  • Article
  • Open Access
5 Citations
2,979 Views
14 Pages

Effectiveness of R1-nj Anthocyanin Marker in the Identification of In Vivo Induced Maize Haploid Embryos

  • Luis Antonio Lopez,
  • John Ochieng,
  • Mario Pacheco,
  • Leocadio Martinez,
  • Hamilton Amoshe Omar,
  • Manje Gowda,
  • Boddupalli M. Prasanna,
  • Kanwarpal S. Dhugga and
  • Vijay Chaikam

14 June 2023

Doubled haploid (DH) technology has become integral to maize breeding programs to expedite inbred line development and increase the efficiency of breeding operations. Unlike many other plant species that use in vitro methods, DH production in maize u...

  • Article
  • Open Access
5 Citations
8,226 Views
12 Pages

Improved Identification of Partial Biotinidase Deficiency by Newborn Screening Using Age-Related Enzyme Activity Cutoffs: Reduction of the False-Positive Rate

  • Nicole VanVleck,
  • Barry Wolf,
  • Mary Seeterlin,
  • Kristin G. Monaghan,
  • Eleanor Stanley,
  • Harry Hawkins and
  • Bonita Taffe

Background: Biotinidase deficiency is an inherited metabolic disorder that if untreated can result in neurological and cutaneous features. Profound biotinidase deficiency presents in early childhood with severe symptoms, whereas partial biotinidase d...

  • Article
  • Open Access
18 Citations
4,169 Views
16 Pages

Real-Time Integration of Segmentation Techniques for Reduction of False Positive Rates in Fire Plume Detection Systems during Forest Fires

  • Leonardo Martins,
  • Federico Guede-Fernández,
  • Rui Valente de Almeida,
  • Hugo Gamboa and
  • Pedro Vieira

4 June 2022

Governmental offices are still highly concerned with controlling the escalation of forest fires due to their social, environmental and economic consequences. This paper presents new developments to a previously implemented system for the classificati...

  • Article
  • Open Access
2,300 Views
21 Pages

20 May 2025

The current replication crisis relating to the non-replicability and the untrustworthiness of published empirical evidence is often viewed through the lens of the Positive Predictive Value (PPV) in the context of the Medical Diagnostic Screening (MDS...

  • Article
  • Open Access
6 Citations
2,835 Views
18 Pages

Statistical Assessment of Discrimination Capabilities of a Fractional Calculus Based Image Watermarking System for Gaussian Watermarks

  • Mario Gonzalez-Lee,
  • Hector Vazquez-Leal,
  • Luis J. Morales-Mendoza,
  • Mariko Nakano-Miyatake,
  • Hector Perez-Meana and
  • Juan R. Laguna-Camacho

23 February 2021

In this paper, we explore the advantages of a fractional calculus based watermarking system for detecting Gaussian watermarks. To reach this goal, we selected a typical watermarking scheme and replaced the detection equation set by another set of equ...

  • Article
  • Open Access
124 Citations
8,578 Views
37 Pages

The Use of Ensemble Models for Multiple Class and Binary Class Classification for Improving Intrusion Detection Systems

  • Celestine Iwendi,
  • Suleman Khan,
  • Joseph Henry Anajemba,
  • Mohit Mittal,
  • Mamdouh Alenezi and
  • Mamoun Alazab

30 April 2020

The pursuit to spot abnormal behaviors in and out of a network system is what led to a system known as intrusion detection systems for soft computing besides many researchers have applied machine learning around this area. Obviously, a single classif...

  • Article
  • Open Access
12 Citations
3,981 Views
11 Pages

Comparison of Tandem Mass Spectrometry and the Fluorometric Method—Parallel Phenylalanine Measurement on a Large Fresh Sample Series and Implications for Newborn Screening for Phenylketonuria

  • Dasa Perko,
  • Urh Groselj,
  • Vanja Cuk,
  • Ziga Iztok Remec,
  • Mojca Zerjav Tansek,
  • Ana Drole Torkar,
  • Blaz Krhin,
  • Ajda Bicek,
  • Adrijana Oblak and
  • Barbka Repic Lampret
  • + 1 author

27 January 2023

Phenylketonuria (PKU) was the first disease to be identified by the newborn screening (NBS) program. Currently, there are various methods for determining phenylalanine (Phe) values, with tandem mass spectrometry (MS/MS) being the most widely used met...

  • Article
  • Open Access
2,207 Views
14 Pages

Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines

  • Daniel I. S. Rosenbloom,
  • Julie Dudášová,
  • Casey Davis,
  • Radha A. Railkar,
  • Nitin Mehrotra and
  • Jeffrey R. Sachs

19 September 2023

In vaccine efficacy trials, inaccurate counting of infection cases leads to systematic under-estimation—or “dilution”—of vaccine efficacy. In particular, if a sufficient fraction of observed cases are false positives, apparent...

  • Review
  • Open Access
7 Citations
4,490 Views
23 Pages

A Review of Cuckoo Filters for Privacy Protection and Their Applications

  • Yekang Zhao,
  • Wangchen Dai,
  • Shiren Wang,
  • Liang Xi,
  • Shenqing Wang and
  • Feng Zhang

As the global digitalization process continues, information is transformed into data and widely used, while the data are also at risk of serious privacy breaches. The Cuckoo filter is a data structure based on the Cuckoo hash. It encrypts data when i...

  • Article
  • Open Access
8 Citations
2,610 Views
16 Pages

This research uses mathematically derived visual logistics to interpret COVID-19 molecular and rapid antigen test (RAgT) performance, determine prevalence boundaries where risk exceeds expectations, and evaluate benefits of recursive testing along ho...

  • Feature Paper
  • Article
  • Open Access
525 Views
35 Pages

23 December 2025

Forensic statisticians have long debated whether searching large DNA databases undermines the evidential value of matches. Modern surveillance faces an exponentially harder problem: screening populations across thousands of attributes using threshold...

  • Article
  • Open Access
2 Citations
2,379 Views
21 Pages

A Novel Forward-Propagation Workflow Assessment Method for Malicious Packet Detection

  • Nagaiah Mohanan Balamurugan,
  • Raju Kannadasan,
  • Mohammed H. Alsharif and
  • Peerapong Uthansakul

30 May 2022

In recent times, there has been a huge upsurge in malicious attacks despite sophisticated technologies in digital network data transmission. This research proposes an innovative method that utilizes the forward-propagation workflow of the convolution...

  • Article
  • Open Access
1 Citations
1,719 Views
15 Pages

Digital-Tier Strategy Improves Newborn Screening for Glutaric Aciduria Type 1

  • Elaine Zaunseder,
  • Julian Teinert,
  • Nikolas Boy,
  • Sven F. Garbade,
  • Saskia Haupt,
  • Patrik Feyh,
  • Georg F. Hoffmann,
  • Stefan Kölker,
  • Ulrike Mütze and
  • Vincent Heuveline

Glutaric aciduria type 1 (GA1) is a rare inherited metabolic disease increasingly included in newborn screening (NBS) programs worldwide. Because of the broad biochemical spectrum of individuals with GA1 and the lack of reliable second-tier strategie...

  • Article
  • Open Access
32 Citations
5,241 Views
14 Pages

Variables Associated with False-Positive PSA Results: A Cohort Study with Real-World Data

  • Blanca Lumbreras,
  • Lucy Anne Parker,
  • Juan Pablo Caballero-Romeu,
  • Luis Gómez-Pérez,
  • Marta Puig-García,
  • Maite López-Garrigós,
  • Nuria García and
  • Ildefonso Hernández-Aguado

30 December 2022

(1) Background: There are no real-world data evaluating the incidence of false-positive results. We analyzed the clinical and analytical factors associated with the presence of false-positive results in PSA determinations in practice. (2) Methods: A...

  • Article
  • Open Access
1 Citations
3,141 Views
10 Pages

Transfusion-transmitted infections (TTIs), such as hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and treponema pallidum (TP), must be detected before blood transfusion. However, few studies have been conducted...

  • Article
  • Open Access
2 Citations
2,835 Views
16 Pages

Background: Preeclampsia, affecting 2–4% of pregnancies worldwide, poses a substantial risk to maternal health. Late-onset preeclampsia, in particular, has a high incidence among preeclampsia cases. However, existing prediction models are limit...

  • Article
  • Open Access
6 Citations
3,951 Views
16 Pages

A Hardware Trojan-Detection Technique Based on Suspicious Circuit Block Partition

  • Jiajie Mao,
  • Xiaowen Jiang,
  • Dehong Liu,
  • Jianjun Chen and
  • Kai Huang

12 December 2022

To ensure that a hardware Trojan remains hidden in a circuit, it is usually necessary to ensure that the trigger signal has a low testability, which has been widely recognized and proven. The most advanced testability-based detection methods are rath...

  • Article
  • Open Access
2 Citations
1,526 Views
16 Pages

Aortic Remodeling After False Lumen Embolization in Aortic Dissection

  • Nancy Halloum,
  • Anna-Sophie Meyer,
  • Martin Wenkel,
  • Daniel-Sebastian Dohle,
  • Marwan Youssef,
  • Bernhard Dorweiler,
  • Hendrik Treede and
  • Hazem El Beyrouti

24 January 2025

Background/Objectives: Retrograde false lumen perfusion after thoracic endovascular aortic repair (TEVAR) can compromise positive remodeling and clinical outcomes. The aim of this study is to describe the feasibility and outcomes of a false lumen thr...

  • Article
  • Open Access
6 Citations
7,563 Views
21 Pages

Phishing remains a persistent cybersecurity threat, often bypassing traditional detection methods due to evolving attack techniques. This study presents a Reinforcement Learning (RL)-based phishing detection framework, leveraging a Deep Q-Network (DQ...

  • Article
  • Open Access
6 Citations
4,746 Views
18 Pages

28 November 2019

A fundamental problem in computer vision is face detection. In this paper, an experimentally derived ensemble made by a set of six face detectors is presented that maximizes the number of true positives while simultaneously reducing the number of fal...

  • Article
  • Open Access
1 Citations
2,080 Views
14 Pages

Diagnostic Utility of the “Air Sign” as a Radiological Indicator for Mandibular Body and Angle Fractures

  • Weronika Michalik,
  • Joanna Kuczera,
  • Jakub Bargiel,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik,
  • Paweł Szczurowski,
  • Grażyna Wyszyńska-Pawelec and
  • Michał Gontarz

21 October 2024

Background: To plan optimal treatment, obtain satisfactory outcomes, and avoid undesirable clinical errors, surgeons need to have efficient tools for providing a complete and prompt diagnosis. The aim of this study was to establish the sensitivity, s...

  • Article
  • Open Access
2 Citations
2,111 Views
15 Pages

Background: Diabetic retinopathy (DR) is the leading cause of blindness among working-age adults. Early detection is crucial to reducing DR-related vision loss risk but is fraught with challenges. Manual detection is labor-intensive and often misses...

  • Article
  • Open Access
11 Citations
2,983 Views
13 Pages

Fault Diagnosis Method for Wind Turbine Gearboxes Based on IWOA-RF

  • Mingzhu Tang,
  • Zixin Liang,
  • Huawei Wu and
  • Zimin Wang

2 October 2021

A fault diagnosis method for wind turbine gearboxes based on undersampling, XGBoost feature selection, and improved whale optimization-random forest (IWOA-RF) was proposed for the problem of high false negative and false positive rates in wind turbin...

  • Article
  • Open Access
1,310 Views
22 Pages

23 May 2025

In this work, we introduce a framework to combine arbitrary image segmentation algorithms from different agents under data privacy constraints to produce an aggregated prediction set satisfying finite-sample risk control guarantees. We leverage distr...

  • Article
  • Open Access
9 Citations
4,339 Views
12 Pages

For newborn screening (NBS) of lysosomal storage diseases, programs measure enzymatic activities in dried blood spots (DBS) and, in most cases, act on samples where the measurement is below a specific cutoff value. The rate of false positives and neg...

  • Article
  • Open Access
87 Citations
7,482 Views
14 Pages

23 April 2019

This work presents a methodology for the short-term forecast of intense rainfall based on a neural network and the integration of Global Navigation and Positioning System (GNSS) and meteorological data. Precipitable water vapor (PWV) derived from GNS...

  • Article
  • Open Access
9 Citations
2,759 Views
8 Pages

First-Trimester Screening for Gestational Diabetes Mellitus in Twin Pregnancies

  • Olga Buerger,
  • Tania Elger,
  • Antonia Varthaliti,
  • Argyro Syngelaki,
  • Alan Wright and
  • Kypros H. Nicolaides

25 August 2021

We previously reported a logistic regression model for prediction of GDM from maternal characteristics and medical history in 75,161 singleton pregnancies. In this study of 1376 twin and 13,760 singleton pregnancies recruited at 11–13 weeks’ gestatio...

  • Article
  • Open Access
45 Citations
6,429 Views
16 Pages

Hybrid Intrusion Detection System Based on Combination of Random Forest and Autoencoder

  • Chao Wang,
  • Yunxiao Sun,
  • Wenting Wang,
  • Hongri Liu and
  • Bailing Wang

21 February 2023

To cope with the rising threats posed by network attacks, machine learning-based intrusion detection systems (IDSs) have been intensively researched. However, there are several issues that need to be addressed. It is difficult to deal with unknown at...

  • Article
  • Open Access
7 Citations
3,418 Views
20 Pages

19 February 2023

Accelerometers are sensitive devices that capture vibrational fault signatures from industrial machines. However, noise often contaminates these fault signatures and must be eliminated before analysis. A data-driven (DD) denoising algorithm capable o...

  • Article
  • Open Access
2 Citations
2,520 Views
16 Pages

Genome-Wide Cell-Free DNA Test for Fetal Chromosomal Abnormalities and Variants: Unrestricted Versus Restricted Reporting

  • Angel H. W. Kwan,
  • Xiaofan Zhu,
  • Maria Mar Gil,
  • Yvonne K. Y. Kwok,
  • Isabella Y. M. Wah,
  • Annie S. Y. Hui,
  • Yuen-Ha Ting,
  • Kwok-Ming Law,
  • Doris Lau and
  • Liona C. Poon
  • + 4 authors

9 October 2022

This study aimed to compare the screening performance of genome-wide cfDNA testing for chromosomal abnormalities between two periods where additional findings were reported and not reported. Data were obtained from consecutive pregnant women with a s...

  • Article
  • Open Access
2 Citations
4,598 Views
14 Pages

13 March 2023

The appropriate management strategies for BI-RADS category 4a lesions among handheld ultrasound (HHUS) remain a matter of debate. We aimed to explore the role of automated breast ultrasound (ABUS) or the second-look mammography (MAM) adjunct to ultra...

  • Article
  • Open Access
1 Citations
2,512 Views
17 Pages

27 February 2024

Unmanned aerial vehicle (UAV) technology has witnessed widespread utilization in target surveillance activities. However, cooperative multiple UAVs for the identification of multiple targets poses a significant challenge due to the susceptibility of...

  • Perspective
  • Open Access
22 Citations
3,474 Views
10 Pages

Accuracy of p16 IHC in Classifying HPV-Driven OPSCC in Different Populations

  • Roberto Gallus,
  • Irene H Nauta,
  • Linda Marklund,
  • Davide Rizzo,
  • Claudia Crescio,
  • Luca Mureddu,
  • Paolo Tropiano,
  • Giovanni Delogu and
  • Francesco Bussu

20 January 2023

High-risk human papillomavirus (HPV) infection is a defined etiopathogenetic factor in oropharyngeal carcinogenesis with a clear prognostic value. The P16 IHC (immunohistochemistry) is a widely accepted marker for HPV-driven carcinogenesis in orophar...

  • Article
  • Open Access
359 Views
17 Pages

AI-Based Pulmonary Embolism Detection: The Added Value of a False-Positive Reduction Module over a Region Proposal Network

  • Jeong Sub Lee,
  • Euijin Hwang,
  • Changgyun Jin,
  • Kyong Joon Lee,
  • Ye Ra Choi and
  • Sang Il Choi

Background: High false-positive rates remain a significant challenge in the automated detection of pulmonary embolism (PE) using Computed Tomography Pulmonary Angiography (CTPA). This study evaluated the additional value of a False-Positive Reduction...

  • Article
  • Open Access
9 Citations
4,399 Views
23 Pages

24 July 2021

Accurate large-area mangrove classification is a challenging task due to the complexity of mangroves, such as abundant species within the mangrove category, and various appearances resulting from a large latitudinal span and varied habitats. Existing...

  • Article
  • Open Access
1 Citations
3,110 Views
11 Pages

Content-Based Approach for Improving Bloom Filter Efficiency

  • Mohammed Alsuhaibani,
  • Rehan Ullah Khan,
  • Ali Mustafa Qamar and
  • Suliman A. Alsuhibany

6 July 2023

Bloom filters are a type of data structure that is used to test whether or not an element is a member of a set. They are known for being space-efficient and are commonly employed in various applications, such as network routers, web browsers, and dat...

  • Article
  • Open Access
9 Citations
4,627 Views
21 Pages

13 December 2022

Based on the appearance of tomatoes, it is possible to determine whether they are diseased. Detecting diseases early can help the yield losses of tomatoes through timely treatment. However, human visual inspection is expensive in terms of the time an...

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