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49 pages, 670 KB  
Review
Bridging Domains: Advances in Explainable, Automated, and Privacy-Preserving AI for Computer Science and Cybersecurity
by Youssef Harrath, Oswald Adohinzin, Jihene Kaabi and Morgan Saathoff
Computers 2025, 14(9), 374; https://doi.org/10.3390/computers14090374 (registering DOI) - 8 Sep 2025
Abstract
Artificial intelligence (AI) is rapidly redefining both computer science and cybersecurity by enabling more intelligent, scalable, and privacy-conscious systems. While most prior surveys treat these fields in isolation, this paper provides a unified review of 256 peer-reviewed publications to bridge that gap. We [...] Read more.
Artificial intelligence (AI) is rapidly redefining both computer science and cybersecurity by enabling more intelligent, scalable, and privacy-conscious systems. While most prior surveys treat these fields in isolation, this paper provides a unified review of 256 peer-reviewed publications to bridge that gap. We examine how emerging AI paradigms, such as explainable AI (XAI), AI-augmented software development, and federated learning, are shaping technological progress across both domains. In computer science, AI is increasingly embedded throughout the software development lifecycle to boost productivity, improve testing reliability, and automate decision making. In cybersecurity, AI drives advances in real-time threat detection and adaptive defense. Our synthesis highlights powerful cross-cutting findings, including shared challenges such as algorithmic bias, interpretability gaps, and high computational costs, as well as empirical evidence that AI-enabled defenses can reduce successful breaches by up to 30%. Explainability is identified as a cornerstone for trust and bias mitigation, while privacy-preserving techniques, including federated learning and local differential privacy, emerge as essential safeguards in decentralized environments such as the Internet of Things (IoT) and healthcare. Despite transformative progress, we emphasize persistent limitations in fairness, adversarial robustness, and the sustainability of large-scale model training. By integrating perspectives from two traditionally siloed disciplines, this review delivers a unified framework that not only maps current advances and limitations but also provides a foundation for building more resilient, ethical, and trustworthy AI systems. Full article
(This article belongs to the Section AI-Driven Innovations)
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16 pages, 604 KB  
Review
Advancing Precision Neurology and Wearable Electrophysiology: A Review on the Pivotal Role of Medical Physicists in Signal Processing, AI, and Prognostic Modeling
by Constantinos Koutsojannis, Athanasios Fouras and Dionysia Chrysanthakopoulou
Biophysica 2025, 5(3), 40; https://doi.org/10.3390/biophysica5030040 - 5 Sep 2025
Viewed by 118
Abstract
Medical physicists are transforming physiological measurements and electrophysiological applications by addressing challenges like motion artifacts and regulatory compliance through advanced signal processing, artificial intelligence (AI), and statistical rigor. Their innovations in wearable electrophysiology achieve 8–12 dB signal-to-noise ratio (SNR) improvements in EEG, 60% [...] Read more.
Medical physicists are transforming physiological measurements and electrophysiological applications by addressing challenges like motion artifacts and regulatory compliance through advanced signal processing, artificial intelligence (AI), and statistical rigor. Their innovations in wearable electrophysiology achieve 8–12 dB signal-to-noise ratio (SNR) improvements in EEG, 60% motion artifact reduction, and 94.2% accurate AI-driven arrhythmia detection at 12 μW power. In precision neurology, machine learning (ML) with evoked potentials (EPs) predicts spinal cord injury (SCI) recovery and multiple sclerosis (MS) progression with 79.2% accuracy based on retrospective data from 560 SCI/MS patients. By integrating multimodal data (EPs, MRI), developing quantum sensors, and employing federated learning, these can enhance diagnostic precision and prognostic accuracy. Clinical applications span epilepsy, stroke, cardiac monitoring, and chronic pain management, reducing diagnostic errors by 28% and optimizing treatments like deep brain stimulation (DBS). In this paper, we review the current state of wearable devices and provide some insight into possible future directions. Embedding medical physicists into standardization efforts is critical to overcoming barriers like quantum sensor power consumption, advancing personalized, evidence-based healthcare. Full article
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29 pages, 1260 KB  
Article
Modelling Social Attachment and Mental States from Facebook Activity with Machine Learning
by Stavroula Kridera and Andreas Kanavos
Information 2025, 16(9), 772; https://doi.org/10.3390/info16090772 - 5 Sep 2025
Viewed by 198
Abstract
Social networks generate vast amounts of data that can reveal patterns of human behaviour, social attachment, and mental states. This paper explores advanced machine learning techniques to detect and model such patterns, focusing on community structures, influential users, and information diffusion pathways. To [...] Read more.
Social networks generate vast amounts of data that can reveal patterns of human behaviour, social attachment, and mental states. This paper explores advanced machine learning techniques to detect and model such patterns, focusing on community structures, influential users, and information diffusion pathways. To address the scale, noise, and heterogeneity of social data, we leverage recent advances in graph theory, natural language processing, and anomaly detection. Our framework combines clustering for community detection, sentiment analysis for emotional state inference, and centrality metrics for influence estimation, while integrating multimodal data—including textual and visual content—for richer behavioural insights. Experimental results demonstrate that the proposed approach effectively extracts actionable knowledge, supporting mental well-being and strengthening digital social ties. Furthermore, we emphasise the role of privacy-preserving methods, such as federated learning, to ensure ethical analysis. These findings lay the groundwork for responsible and effective applications of machine learning in social network analysis. Full article
(This article belongs to the Special Issue Information Extraction and Language Discourse Processing)
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14 pages, 962 KB  
Review
Artificial Intelligence and Advanced Digital Health for Hypertension: Evolving Tools for Precision Cardiovascular Care
by Ioannis Skalidis, Niccolo Maurizi, Adil Salihu, Stephane Fournier, Stephane Cook, Juan F. Iglesias, Pietro Laforgia, Livio D’Angelo, Philippe Garot, Thomas Hovasse, Antoinette Neylon, Thierry Unterseeh, Stephane Champagne, Nicolas Amabile, Neila Sayah, Francesca Sanguineti, Mariama Akodad, Henri Lu and Panagiotis Antiochos
Medicina 2025, 61(9), 1597; https://doi.org/10.3390/medicina61091597 - 4 Sep 2025
Viewed by 279
Abstract
Background: Hypertension remains the leading global risk factor for cardiovascular morbidity and mortality, with suboptimal control rates despite guideline-directed therapies. Digital health and artificial intelligence (AI) technologies offer novel approaches for improving diagnosis, monitoring, and individualized treatment of hypertension. Objectives: To [...] Read more.
Background: Hypertension remains the leading global risk factor for cardiovascular morbidity and mortality, with suboptimal control rates despite guideline-directed therapies. Digital health and artificial intelligence (AI) technologies offer novel approaches for improving diagnosis, monitoring, and individualized treatment of hypertension. Objectives: To critically review the current landscape of AI-enabled digital tools for hypertension management, including emerging applications, implementation challenges, and future directions. Methods: A narrative review of recent PubMed-indexed studies (2019–2024) was conducted, focusing on clinical applications of AI and digital health technologies in hypertension. Emphasis was placed on real-world deployment, algorithmic explainability, digital biomarkers, and ethical/regulatory frameworks. Priority was given to high-quality randomized trials, systematic reviews, and expert consensus statements. Results: AI-supported platforms—including remote blood pressure monitoring, machine learning titration algorithms, and digital twins—have demonstrated early promise in improving hypertension control. Explainable AI (XAI) is critical for clinician trust and integration into decision-making. Equity-focused design and regulatory oversight are essential to prevent exacerbation of health disparities. Emerging implementation strategies, such as federated learning and co-design frameworks, may enhance scalability and generalizability across diverse care settings. Conclusions: AI-guided titration and digital twin approaches appear most promising for reducing therapeutic inertia, whereas cuffless blood pressure monitoring remains the least mature. Future work should prioritize pragmatic trials with equity and cost-effectiveness endpoints, supported by safeguards against bias, accountability gaps, and privacy risks. Full article
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22 pages, 3493 KB  
Article
NeuroFed-LightTCN: Federated Lightweight Temporal Convolutional Networks for Privacy-Preserving Seizure Detection in EEG Data
by Zheng You Lim, Ying Han Pang, Shih Yin Ooi, Wee How Khoh and Yee Jian Chew
Appl. Sci. 2025, 15(17), 9660; https://doi.org/10.3390/app15179660 - 2 Sep 2025
Viewed by 268
Abstract
This study investigates on-edge seizure detection that aims to resolve two major constraints that hold the deployment of deep learning models in clinical settings at present. First, centralized training requires gathering and consolidating data across institutions, which poses a serious issue of privacy. [...] Read more.
This study investigates on-edge seizure detection that aims to resolve two major constraints that hold the deployment of deep learning models in clinical settings at present. First, centralized training requires gathering and consolidating data across institutions, which poses a serious issue of privacy. Second, a high computational overhead inherent in inference imposes a crushing burden on resource-limited edge devices. Hence, we propose NeuroFed-LightTCN, a federated learning (FL) framework, incorporating a lightweight temporal convolutional network (TCN), designed for resource-efficient and privacy-preserving seizure detection. The proposed framework integrates depthwise separable convolutions, grouped with structured pruning to enhance efficiency, scalability, and performance. Furthermore, asynchronous aggregation is employed to mitigate training overhead. Empirical tests demonstrate that the network can be reduced fully to 70% with a 44.9% decrease in parameters (65.4 M down to 34.9 M and an inferencing latency of 56 ms) and still maintain 97.11% accuracy, a metric that outperforms both the non-FL and FL TCN optimizations. Ablation shows that asynchronous aggregation reduces training times by 3.6 to 18%, and pruning sustains performance even at extreme sparsity: an F1-score of 97.17% at a 70% pruning rate. Overall, the proposed NeuroFed-LightTCN addresses the trade-off between computational efficiency and model performance, delivering a viable solution to federated edge-device learning. Through the interaction of federated-optimization-driven approaches and lightweight architectural innovation, scalable and privacy-aware machine learning can be a practical reality, without compromising accuracy, and so its potential utility can be expanded to the real world. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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21 pages, 7375 KB  
Article
Real-Time Face Mask Detection Using Federated Learning
by Tudor-Mihai David and Mihai Udrescu
Computers 2025, 14(9), 360; https://doi.org/10.3390/computers14090360 - 31 Aug 2025
Viewed by 288
Abstract
Epidemics caused by respiratory infections have become a global and systemic threat since humankind has become highly connected via modern transportation systems. Any new pathogen with human-to-human transmission capabilities has the potential to cause public health disasters and severe disruptions of social and [...] Read more.
Epidemics caused by respiratory infections have become a global and systemic threat since humankind has become highly connected via modern transportation systems. Any new pathogen with human-to-human transmission capabilities has the potential to cause public health disasters and severe disruptions of social and economic activities. During the COVID-19 pandemic, we learned that proper mask-wearing in closed, restricted areas was one of the measures that worked to mitigate the spread of respiratory infections while allowing for continuing economic activity. Previous research approached this issue by designing hardware–software systems that determine whether individuals in the surveilled restricted area are using a mask; however, most such solutions are centralized, thus requiring massive computational resources, which makes them hard to scale up. To address such issues, this paper proposes a novel decentralized, federated learning (FL) solution to mask-wearing detection that instantiates our lightweight version of the MobileNetV2 model. The FL solution also ensures individual privacy, given that images remain at the local, device level. Importantly, we obtained a mask-wearing training accuracy of 98% (i.e., similar to centralized machine learning solutions) after only eight rounds of communication with 25 clients. We rigorously proved the reliability and robustness of our approach after repeated K-fold cross-validation. Full article
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20 pages, 3787 KB  
Article
Federated Learning for XSS Detection: Analysing OOD, Non-IID Challenges, and Embedding Sensitivity
by Bo Wang, Imran Khan, Martin White and Natalia Beloff
Electronics 2025, 14(17), 3483; https://doi.org/10.3390/electronics14173483 - 31 Aug 2025
Viewed by 297
Abstract
This paper investigates federated learning (FL) for cross-site scripting (XSS) detection under out-of-distribution (OOD) drift. Real-world XSS traffic involves fragmented attacks, heterogeneous benign inputs, and client imbalance, which erode conventional detectors. To simulate this, we construct two structurally divergent datasets: one with obfuscated, [...] Read more.
This paper investigates federated learning (FL) for cross-site scripting (XSS) detection under out-of-distribution (OOD) drift. Real-world XSS traffic involves fragmented attacks, heterogeneous benign inputs, and client imbalance, which erode conventional detectors. To simulate this, we construct two structurally divergent datasets: one with obfuscated, mixed-structure samples and another with syntactically regular examples, inducing structural OOD in both classes. We evaluate GloVe, GraphCodeBERT, and CodeT5 in both centralised and federated settings, tracking embedding drift and client variance. FL consistently improves OOD robustness by averaging decision boundaries from cleaner clients. Under FL scenarios, CodeT5 achieves the best aggregated performance (97.6% accuracy, 3.5% FPR), followed by GraphCodeBERT (96.8%, 4.7%), but is more stable on convergence. GloVe reaches a competitive final accuracy (96.2%) but exhibits a high instability across rounds, with a higher false positive rate (5.5%) and pronounced variance under FedProx. These results highlight the value and limits of structure-aware embeddings and support FL as a practical, privacy-preserving defence within OOD XSS scenarios. Full article
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23 pages, 5273 KB  
Article
Federated Learning Detection of Cyberattacks on Virtual Synchronous Machines Under Grid-Forming Control Using Physics-Informed LSTM
by Ali Khaleghi, Soroush Oshnoei and Saeed Mirzajani
Fractal Fract. 2025, 9(9), 569; https://doi.org/10.3390/fractalfract9090569 - 29 Aug 2025
Viewed by 556
Abstract
The global shift toward clean production, like using renewable energy, has significantly decreased the use of synchronous machines (SMs), which help maintain stability and control, causing serious frequency stability issues in power systems with low inertia. Fractional order controller-based virtual synchronous machines (FOC-VSMs) [...] Read more.
The global shift toward clean production, like using renewable energy, has significantly decreased the use of synchronous machines (SMs), which help maintain stability and control, causing serious frequency stability issues in power systems with low inertia. Fractional order controller-based virtual synchronous machines (FOC-VSMs) have become a promising option, but they rely on communication networks to work together in real time, causing them to be at risk of cyberattacks, especially from false data injection attacks (FDIAs). This paper suggests a new way to detect FDI attacks using a federated physics-informed long short-term memory (PI-LSTM) network. Each FOC-VSM uses its data to train a PI-LSTM, which keeps the information private but still helps it learn from a common model that understands various operating conditions. The PI-LSTM incorporates physical constraints derived from the FOC-VSM swing equation, facilitating residual-based anomaly detection that is sensitive to minor deviations in control dynamics, such as altered inertia or falsified frequency signals. Unlike traditional LSTMs, the physics-informed architecture minimizes false positives arising from benign disturbances. We assessed the proposed method on an IEEE 9-bus test system featuring two FOC-VSMs. The results show that our method can successfully detect FDI attacks while handling regular changes, proving it could be a strong solution. Full article
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56 pages, 7375 KB  
Article
A Two-Stage Hybrid Federated Learning Framework for Privacy-Preserving IoT Anomaly Detection and Classification
by Mohammad Shahin, Ali Hosseinzadeh and F. Frank Chen
IoT 2025, 6(3), 48; https://doi.org/10.3390/iot6030048 - 29 Aug 2025
Viewed by 726
Abstract
The rapid surge of Artificial Internet-of-Things (AIoT) devices has outpaced the deployment of robust, privacy-preserving anomaly detection solutions suitable for resource-constrained edge environments. This paper presents a two-stage hybrid Federated Learning (FL) framework for IoT anomaly detection and classification, validated on the real-world [...] Read more.
The rapid surge of Artificial Internet-of-Things (AIoT) devices has outpaced the deployment of robust, privacy-preserving anomaly detection solutions suitable for resource-constrained edge environments. This paper presents a two-stage hybrid Federated Learning (FL) framework for IoT anomaly detection and classification, validated on the real-world N-BaIoT dataset. In the first stage, each device trains a generative Artificial Intelligence (AI) model on benign traffic only, and in the second stage a Histogram-based Gradient-Boosting (HGB) classifier labels flagged traffic. All models operate under a synchronous, collaborative FL architecture across nine commercial IoT devices, thus preserving data privacy and minimizing communication. Through both inter- and intra-benchmarking against state-of-the-art baselines, the Variational Autoencoder–HGB (VAE-HGB) pipeline emerges as the top performer, achieving an average end-to-end accuracy of 99.14% across all classes. These results demonstrate that reconstruction-driven generative AI models, when combined with federated averaging and efficient classification, deliver a highly scalable, accurate, and privacy-preserving solution for securing resource-constrained IoT environments. Full article
(This article belongs to the Special Issue AIoT-Enabled Sustainable Smart Manufacturing)
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21 pages, 2213 KB  
Review
AI in Dentistry: Innovations, Ethical Considerations, and Integration Barriers
by Tao-Yuan Liu, Kun-Hua Lee, Arvind Mukundan, Riya Karmakar, Hardik Dhiman and Hsiang-Chen Wang
Bioengineering 2025, 12(9), 928; https://doi.org/10.3390/bioengineering12090928 - 29 Aug 2025
Viewed by 655
Abstract
Background/Objectives: Artificial Intelligence (AI) is improving dentistry through increased accuracy in diagnostics, planning, and workflow automation. AI tools, including machine learning (ML) and deep learning (DL), are being adopted in oral medicine to improve patient care, efficiency, and lessen clinicians’ workloads. AI in [...] Read more.
Background/Objectives: Artificial Intelligence (AI) is improving dentistry through increased accuracy in diagnostics, planning, and workflow automation. AI tools, including machine learning (ML) and deep learning (DL), are being adopted in oral medicine to improve patient care, efficiency, and lessen clinicians’ workloads. AI in dentistry, despite its use, faces an issue of acceptance, with its obstacles including ethical, legal, and technological ones. In this article, a review of current AI use in oral medicine, new technology development, and integration barriers is discussed. Methods: A narrative review of peer-reviewed articles in databases such as PubMed, Scopus, Web of Science, and Google Scholar was conducted. Peer-reviewed articles over the last decade, such as AI application in diagnostic imaging, predictive analysis, real-time documentation, and workflows automation, were examined. Besides, improvements in AI models and critical impediments such as ethical concerns and integration barriers were addressed in the review. Results: AI has exhibited strong performance in radiographic diagnostics, with high accuracy in reading cone-beam computed tomography (CBCT) scan, intraoral photographs, and radiographs. AI-facilitated predictive analysis has enhanced personalized care planning and disease avoidance, and AI-facilitated automation of workflows has maximized administrative workflows and patient record management. U-Net-based segmentation models exhibit sensitivities and specificities of approximately 93.0% and 88.0%, respectively, in identifying periapical lesions on 2D CBCT slices. TensorFlow-based workflow modules, integrated into vendor platforms such as Planmeca Romexis, can reduce the processing time of patient records by a minimum of 30 percent in standard practice. The privacy-preserving federated learning architecture has attained cross-site model consistency exceeding 90% accuracy, enabling collaborative training among diverse dentistry clinics. Explainable AI (XAI) and federated learning have enhanced AI transparency and security with technological advancement, but barriers include concerns regarding data privacy, AI bias, gaps in AI regulating, and training clinicians. Conclusions: AI is revolutionizing dentistry with enhanced diagnostic accuracy, predictive planning, and efficient administration automation. With technology developing AI software even smarter, ethics and legislation have to follow in order to allow responsible AI integration. To make AI in dental care work at its best, future research will have to prioritize AI interpretability, developing uniform protocols, and collaboration between specialties in order to allow AI’s full potential in dentistry. Full article
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29 pages, 611 KB  
Article
Enhancing the Multikey GSW Scheme with CRT Decomposition and Ciphertext Compression for Efficient Distributed Decryption
by Kung-Wei Hu, Wun-Ting Lin, Huan-Chih Wang and Ja-Ling Wu
Cryptography 2025, 9(3), 55; https://doi.org/10.3390/cryptography9030055 - 27 Aug 2025
Viewed by 273
Abstract
This paper enhances the multikey scenario in the Gentry–Sahai–Waters (GSW) fully homomorphic encryption scheme to increase its real-world applicability. We integrate the advantages of two existing GSW multikey approaches: one enabling distributed decryption and the other reducing memory requirements. We also apply the [...] Read more.
This paper enhances the multikey scenario in the Gentry–Sahai–Waters (GSW) fully homomorphic encryption scheme to increase its real-world applicability. We integrate the advantages of two existing GSW multikey approaches: one enabling distributed decryption and the other reducing memory requirements. We also apply the CRT decomposition and ciphertext compression techniques to the multikey settings. While leveraging the effectiveness of decomposition, we adapt the compression technique for practical cryptographic applications, as demonstrated through simulations in federated learning and multiparty communication scenarios. Our work’s potential impact on the cryptography field is significant, as it offers a more efficient and secure solution for distributed data processing in real-world scenarios, thereby advancing the state of the art in secure communication systems. Full article
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22 pages, 1989 KB  
Review
Machine Learning Models for Predicting Gynecological Cancers: Advances, Challenges, and Future Directions
by Pankaj Garg, Madhu Krishna, Prakash Kulkarni, David Horne, Ravi Salgia and Sharad S. Singhal
Cancers 2025, 17(17), 2799; https://doi.org/10.3390/cancers17172799 - 27 Aug 2025
Viewed by 610
Abstract
Gynecological cancer, especially breast, cervical, and ovarian cancer, are significant health issues affecting women worldwide. When screened they are mostly detected at later stages because of non-specific signs and symptoms as well as the unavailability of reliable screening methods. The improvement of early [...] Read more.
Gynecological cancer, especially breast, cervical, and ovarian cancer, are significant health issues affecting women worldwide. When screened they are mostly detected at later stages because of non-specific signs and symptoms as well as the unavailability of reliable screening methods. The improvement of early oncologic prediction methods is therefore needed to work out the survival rates, guide individualized treatment, and relieve healthcare pressures. Outcome forecasting and clinical detection are rapidly changing with the use of machine learning (ML), one of the promising technologies used to analyze complex biomedical data. Artificial intelligence (AI)-based ML models are capable of determining low-level trends and making accurate predictions of disease risk and outcomes, because they can combine different datasets (clinical records, genomics, proteomics, medical imaging) and learn to identify subtle patterns. Standard algorithms, including support vector machines, random forests, and deep learning (DL) models, such as convolutional neural networks, have demonstrated high potential in identifying the type of cancer, monitoring disease progression, and designing treatment patterns. This manuscript reviews the recent developments in the use of ML models to advance oncologic prediction tasks in gynecologic oncology. It reports on critical domains, like screening, risk classification, and survival modeling, as well as comments on difficulties, like data inconsistency, inability of interpretation of models, and issues of clinical interpretation. New developments, such as explainable AI, federated learning (FL), and multi-omics fusion, are discussed to develop these models and to make them applicable in practice because of their reliability. Conclusively, this article emphasizes the transformative role of ML in precision oncology to deliver improved, patient-centered outcomes to women who are victims of gynecological cancers. Full article
(This article belongs to the Special Issue Advancements in Preclinical Models for Solid Cancers)
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23 pages, 6848 KB  
Review
The Expanding Frontier: The Role of Artificial Intelligence in Pediatric Neuroradiology
by Alessia Guarnera, Antonio Napolitano, Flavia Liporace, Fabio Marconi, Maria Camilla Rossi-Espagnet, Carlo Gandolfo, Andrea Romano, Alessandro Bozzao and Daniela Longo
Children 2025, 12(9), 1127; https://doi.org/10.3390/children12091127 - 27 Aug 2025
Viewed by 535
Abstract
Artificial intelligence (AI) is revolutionarily shaping the entire landscape of medicine and particularly the privileged field of radiology, since it produces a significant amount of data, namely, images. Currently, AI implementation in radiology is continuously increasing, from automating image analysis to enhancing workflow [...] Read more.
Artificial intelligence (AI) is revolutionarily shaping the entire landscape of medicine and particularly the privileged field of radiology, since it produces a significant amount of data, namely, images. Currently, AI implementation in radiology is continuously increasing, from automating image analysis to enhancing workflow management, and specifically, pediatric neuroradiology is emerging as an expanding frontier. Pediatric neuroradiology presents unique opportunities and challenges since neonates’ and small children’s brains are continuously developing, with age-specific changes in terms of anatomy, physiology, and disease presentation. By enhancing diagnostic accuracy, reducing reporting times, and enabling earlier intervention, AI has the potential to significantly impact clinical practice and patients’ quality of life and outcomes. For instance, AI reduces MRI and CT scanner time by employing advanced deep learning (DL) algorithms to accelerate image acquisition through compressed sensing and undersampling, and to enhance image reconstruction by denoising and super-resolving low-quality datasets, thereby producing diagnostic-quality images with significantly fewer data points and in a shorter timeframe. Furthermore, as healthcare systems become increasingly burdened by rising demands and limited radiology workforce capacity, AI offers a practical solution to support clinical decision-making, particularly in institutions where pediatric neuroradiology is limited. For example, the MELD (Multicenter Epilepsy Lesion Detection) algorithm is specifically designed to help radiologists find focal cortical dysplasias (FCDs), which are a common cause of drug-resistant epilepsy. It works by analyzing a patient’s MRI scan and comparing a wide range of features—such as cortical thickness and folding patterns—to a large database of scans from both healthy individuals and epilepsy patients. By identifying subtle deviations from normal brain anatomy, the MELD graph algorithm can highlight potential lesions that are often missed by the human eye, which is a critical step in identifying patients who could benefit from life-changing epilepsy surgery. On the other hand, the integration of AI into pediatric neuroradiology faces technical and ethical challenges, such as data scarcity and ethical and legal restrictions on pediatric data sharing, that complicate the development of robust and generalizable AI models. Moreover, many radiologists remain sceptical of AI’s interpretability and reliability, and there are also important medico-legal questions around responsibility and liability when AI systems are involved in clinical decision-making. Future promising perspectives to overcome these concerns are represented by federated learning and collaborative research and AI development, which require technological innovation and multidisciplinary collaboration between neuroradiologists, data scientists, ethicists, and pediatricians. The paper aims to address: (1) current applications of AI in pediatric neuroradiology; (2) current challenges and ethical considerations related to AI implementation in pediatric neuroradiology; and (3) future opportunities in the clinical and educational pediatric neuroradiology field. AI in pediatric neuroradiology is not meant to replace neuroradiologists, but to amplify human intellect and extend our capacity to diagnose, prognosticate, and treat with unprecedented precision and speed. Full article
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38 pages, 6294 KB  
Systematic Review
Machine Learning-Driven Advancements in Electric Motorcycles: A Systematic Review of Electric Motors, Energy Storage, Charging Technologies, and Electronic Components
by Lukasz Pawlik, Jacek Lukasz Wilk-Jakubowski, Krzysztof Podosek and Grzegorz Wilk-Jakubowski
Energies 2025, 18(17), 4529; https://doi.org/10.3390/en18174529 - 26 Aug 2025
Viewed by 695
Abstract
The integration of artificial intelligence (AI) and machine learning (ML) technologies is rapidly transforming the design, operation, and optimization of electric motorcycles. This review analyzes research published between 2015 and 2024, focusing on how ML algorithms enhance performance, energy efficiency, diagnostics, and charging [...] Read more.
The integration of artificial intelligence (AI) and machine learning (ML) technologies is rapidly transforming the design, operation, and optimization of electric motorcycles. This review analyzes research published between 2015 and 2024, focusing on how ML algorithms enhance performance, energy efficiency, diagnostics, and charging strategies across four key domains: electric motors, energy storage, charging systems, and electronic components. The review highlights state-of-the-art solutions such as torque and range prediction using LSTM/GRU models, predictive maintenance via CNNs and autoencoders, energy flow control in hybrid battery–supercapacitor systems using reinforcement learning, and federated learning for privacy-preserving embedded applications. Comparative insights reveal quantifiable performance gains over traditional methods, while integrated frameworks are proposed for linking ML diagnostics, Vehicle-to-Grid (V2G) functionalities, and renewable energy integration. The paper concludes with targeted recommendations for future research, including lightweight edge-deployable models, Explainable AI for safety-critical applications, and the fusion of intelligent charging with eco-design principles, aiming to enable intelligent, sustainable, and high-performance electric motorcycle systems. Full article
(This article belongs to the Special Issue Novel and Emerging Energy Systems)
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30 pages, 815 KB  
Review
Next-Generation Machine Learning in Healthcare Fraud Detection: Current Trends, Challenges, and Future Research Directions
by Kamran Razzaq and Mahmood Shah
Information 2025, 16(9), 730; https://doi.org/10.3390/info16090730 - 25 Aug 2025
Viewed by 1012
Abstract
The growing complexity and size of healthcare systems have rendered fraud detection increasingly challenging; however, the current literature lacks a holistic view of the latest machine learning (ML) techniques with practical implementation concerns. The present study addresses this gap by highlighting the importance [...] Read more.
The growing complexity and size of healthcare systems have rendered fraud detection increasingly challenging; however, the current literature lacks a holistic view of the latest machine learning (ML) techniques with practical implementation concerns. The present study addresses this gap by highlighting the importance of machine learning (ML) in preventing and mitigating healthcare fraud, evaluating recent advancements, investigating implementation barriers, and exploring future research dimensions. To further address the limited research on the evaluation of machine learning (ML) and hybrid approaches, this study considers a broad spectrum of ML techniques, including supervised ML, unsupervised ML, deep learning, and hybrid ML approaches such as SMOTE-ENN, explainable AI, federated learning, and ensemble learning. The study also explored their potential use in enhancing fraud detection in imbalanced and multidimensional datasets. A significant finding of the study was the identification of commonly employed datasets, such as Medicare, the List of Excluded Individuals and Entities (LEIE), and Kaggle datasets, which serve as a baseline for evaluating machine learning (ML) models. The study’s findings comprehensively identify the challenges of employing machine learning (ML) in healthcare systems, including data quality, system scalability, regulatory compliance, and resource constraints. The study provides actionable insights, such as model interpretability to enable regulatory compliance and federated learning for confidential data sharing, which is particularly relevant for policymakers, healthcare providers, and insurance companies that intend to deploy a robust, scalable, and secure fraud detection infrastructure. The study presents a comprehensive framework for enhancing real-time healthcare fraud detection through self-learning, interpretable, and safe machine learning (ML) infrastructures, integrating theoretical advancements with practical application needs. Full article
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