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Keywords = hypertrophic osteopathy

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13 pages, 4034 KB  
Article
Computed Tomographic Findings in Dogs with Presumed Metaphyseal Osteopathy
by Giulia Dalla Serra, Cliona Skelly and Olga Amorós Carafí
Vet. Sci. 2025, 12(9), 813; https://doi.org/10.3390/vetsci12090813 - 26 Aug 2025
Viewed by 1007
Abstract
Metaphyseal osteopathy (MO) is a rare systemic disease primarily affecting young large-breed dogs. Diagnosis of MO is usually based on a combination of signalment, presenting clinical signs, and imaging findings. While radiographic features of MO are well documented, reports describing Computed Tomography (CT) [...] Read more.
Metaphyseal osteopathy (MO) is a rare systemic disease primarily affecting young large-breed dogs. Diagnosis of MO is usually based on a combination of signalment, presenting clinical signs, and imaging findings. While radiographic features of MO are well documented, reports describing Computed Tomography (CT) findings are limited. Clinical records of a veterinary teaching hospital were searched for dogs with a presumed diagnosis of MO that underwent CT imaging. CT and available radiographic studies were retrospectively reviewed. Four dogs met the inclusion criteria. All presented with pyrexia, often associated with other clinical signs. CT lesions were bilateral and symmetric in all cases, characterised by an irregular metaphyseal band of lysis parallel to the physis with associated signs of bone sclerosis. Multiple long bones were affected, and mandibular involvement was suspected in two cases. Comparison with a radiographic study was available in two cases, and follow-up CT imaging was performed in one. Although radiographs remain the primary diagnostic tool for MO, understanding the CT features of the disease is valuable and may contribute to prompt diagnosis, particularly when evaluating young dogs with pyrexia and non-specific clinical signs. Full article
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8 pages, 2448 KB  
Case Report
Successful Treatment of Renal Cell Carcinoma Associated with Hypertrophic Osteopathy in a Cat
by Takashi Tanaka, Midori Tanaka, Tomoyuki Tezuka, Kazumi Shimada and Ryo Tanaka
Vet. Sci. 2024, 11(12), 669; https://doi.org/10.3390/vetsci11120669 - 20 Dec 2024
Cited by 1 | Viewed by 3790
Abstract
An eight-year-old spayed female Abyssinian cat presented with lameness. Palpation revealed swelling, heat, and a reduced range of motion in the stifle and tarsal joints in both hind limbs. A radiographic examination of both hind limbs revealed periosteal proliferation from the distal tibia [...] Read more.
An eight-year-old spayed female Abyssinian cat presented with lameness. Palpation revealed swelling, heat, and a reduced range of motion in the stifle and tarsal joints in both hind limbs. A radiographic examination of both hind limbs revealed periosteal proliferation from the distal tibia to the tarsal and metatarsal bones, which suggested hypertrophic osteopathy. Thorax and abdominal radiographic examinations were performed to identify the primary disease. Complete blood count and routine serum biochemistry tests revealed no abnormalities. No obvious anomalies were evident in the thoracic radiograph; however, a mass was observed near the left kidney on an abdominal radiograph. An abdominal ultrasound was performed, which revealed a hypoechoic renal mass located in the caudal pole of the left kidney. The left nephrectomy was performed after exploration of the abdominal cavity confirmed an abnormality in the left kidney. A histopathological examination revealed renal cell carcinoma. The cat was subsequently fed on a renal prescription diet but received no additional treatment. The periosteal lesion in the distal tibia regressed over time, but the lesions remained in the talus and metatarsal bones. At 1670 days following surgery, blood tests indicated that urea nitrogen and creatinine were above the normal range. In addition, urinalysis revealed an isosthenuria. However, the cat survived over 4500 days following surgery. Full article
(This article belongs to the Special Issue Focus on Tumours in Pet Animals)
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8 pages, 17760 KB  
Case Report
Hypertrophic Osteopathy Concurrent with an Aberrant Right Subclavian Artery in a Dog
by Young-Rok Kim and Jung-Hyun Kim
Vet. Sci. 2024, 11(6), 263; https://doi.org/10.3390/vetsci11060263 - 7 Jun 2024
Viewed by 3526
Abstract
A 13-year-old spayed female cocker spaniel was presented with a 2-month history of swelling in several digits and intermittent hindlimb lameness. Radiographs revealed marked soft-tissue swelling and periosteal new bone formation without cortical bone destruction, characteristic of hypertrophic osteopathy (HO), in the distal [...] Read more.
A 13-year-old spayed female cocker spaniel was presented with a 2-month history of swelling in several digits and intermittent hindlimb lameness. Radiographs revealed marked soft-tissue swelling and periosteal new bone formation without cortical bone destruction, characteristic of hypertrophic osteopathy (HO), in the distal parts of all extremities except for the right forelimb. However, no notable findings were detected in thoracic radiographs. An ultrasonography indicated cranial bladder wall thickening, which resolved following antibiotic therapy. Computed tomographic angiography identified a potential underlying cause as an aberrant right subclavian artery (ARSA) originating from the aortic arch, compressing the esophagus and causing mild esophageal cranial dilation to the aberrant vessel. No other intrathoracic or neoplastic lesions were observed. Gastrointestinal symptoms, such as regurgitation, were absent. Although an ARSA was likely the cause of HO, surgical correction was declined by the owner. To the best of our knowledge, this is the first reported case of HO concurrent with ARSA in dogs. Full article
(This article belongs to the Section Veterinary Internal Medicine)
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7 pages, 5852 KB  
Case Report
Hypertrophic Osteopathy Associated with a Prostatic Adenocarcinoma in a Castrated Dog
by Françoise A. Roux, Emilie Deseille, Marion Fusellier, Marine Rohel, Julien Branchereau and Jack-Yves Deschamps
Vet. Sci. 2022, 9(9), 466; https://doi.org/10.3390/vetsci9090466 - 30 Aug 2022
Cited by 3 | Viewed by 5701
Abstract
A 6-year-old mixed-breed male Papillon dog, castrated at the age of 7 months, presented for work-up of a difficulty walking associated with constipation and urinary incontinence. Ultrasonography and radiography were consistent with a tumor of the prostate and lymph node metastases. An irregular [...] Read more.
A 6-year-old mixed-breed male Papillon dog, castrated at the age of 7 months, presented for work-up of a difficulty walking associated with constipation and urinary incontinence. Ultrasonography and radiography were consistent with a tumor of the prostate and lymph node metastases. An irregular osteoproliferation of the ventral edges of L5–L6–L7 suggested tumor invasion. Periosteal proliferative lesions of the pelvis, the femur, the humerus, the tibia and the calcaneus were consistent with hypertrophic osteopathy. Necropsy and histological examination confirmed the diagnosis of prostatic adenocarcinoma with lymph node, pulmonary, liver and bone metastases, associated with hypertrophic osteopathy. Full article
(This article belongs to the Section Veterinary Reproduction and Obstetrics)
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