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110 Results Found

  • Article
  • Open Access
2,937 Views
16 Pages

Semantic Variant of Primary Progressive Aphasia (svPPA) has often been considered as a loss of knowledge stored in semantic memory, but might also be due to a general disruption of mechanisms allowing the acquisition, storage, and retrieval of semant...

  • Article
  • Open Access
8 Citations
3,242 Views
12 Pages

Differential Diagnosis of Alzheimer Disease vs. Mild Cognitive Impairment Based on Left Temporal Lateral Lobe Hypomethabolism on 18F-FDG PET/CT and Automated Classifiers

  • Susanna Nuvoli,
  • Francesco Bianconi,
  • Maria Rondini,
  • Achille Lazzarato,
  • Andrea Marongiu,
  • Mario Luca Fravolini,
  • Silvia Cascianelli,
  • Serena Amici,
  • Luca Filippi and
  • Barbara Palumbo
  • + 1 author

7 October 2022

Purpose: We evaluate the ability of Artificial Intelligence with automatic classification methods applied to semi-quantitative data from brain 18F-FDG PET/CT to improve the differential diagnosis between Alzheimer Disease (AD) and Mild Cognitive Impa...

  • Case Report
  • Open Access
4 Citations
3,618 Views
7 Pages

27 August 2021

Background: Intracranial dermoid cyst is a rare, benign, nonneoplastic tumor-like lesion that could cause seizures, headache, and hydrocephalus. We hypothesized that the temporal lobe dermoid cyst in combination with other factors were causing the ep...

  • Case Report
  • Open Access
4 Citations
2,737 Views
8 Pages

Intraparenchymal and Subarachnoid Hemorrhage in Stereotactic Electroencephalography Caused by Indirect Adjacent Arterial Injury: Illustrative Case

  • Toshiyuki Kawashima,
  • Takehiro Uda,
  • Saya Koh,
  • Vich Yindeedej,
  • Noboru Ishino,
  • Tsutomu Ichinose,
  • Hironori Arima,
  • Satoru Sakuma and
  • Takeo Goto

The complication rate of stereotactic electroencephalography (SEEG) is generally low, but various types of postoperative hemorrhage have been reported. We presented an unusual hemorrhagic complication after SEEG placement. A 20-year-old man presented...

  • Article
  • Open Access
11 Citations
4,712 Views
11 Pages

This study investigated the relationship between the structural characteristics of the left arcuate fasciculus (AF) reconstructed using diffusion tensor image (DTI) and the type of fluent aphasia according to hemorrhage lesions in patients with fluen...

  • Feature Paper
  • Article
  • Open Access
15 Citations
4,869 Views
19 Pages

Anhedonia in Semantic Dementia—Exploring Right Hemispheric Contributions to the Loss of Pleasure

  • Siobhán R. Shaw,
  • Hashim El-Omar,
  • Siddharth Ramanan,
  • Olivier Piguet,
  • Rebekah M. Ahmed,
  • Alexis E. Whitton and
  • Muireann Irish

Semantic dementia (SD) is a younger-onset neurodegenerative disease characterised by progressive deterioration of the semantic knowledge base in the context of predominantly left-lateralised anterior temporal lobe (ATL) atrophy. Mounting evidence ind...

  • Article
  • Open Access
2 Citations
2,767 Views
11 Pages

Dynamic Amyloid and Metabolic Signatures of Delayed Recall Performance within the Clinical Spectrum of Alzheimer’s Disease

  • Marina Tedeschi Dauar,
  • Tharick Ali Pascoal,
  • Joseph Therriault,
  • Jared Rowley,
  • Sara Mohaddes,
  • Monica Shin,
  • Eduardo R. Zimmer,
  • Simon Fristed Eskildsen,
  • Vladimir S. Fonov and
  • Pedro Rosa-Neto
  • + 2 authors

30 January 2023

Associations between pathophysiological events and cognitive measures provide insights regarding brain networks affected during the clinical progression of Alzheimer’s disease (AD). In this study, we assessed patients’ scores in two delay...

  • Article
  • Open Access
5 Citations
4,076 Views
20 Pages

30 October 2020

Previously published models of frontal activity linked high relative left frontal activity to the behavioral approach system (BAS) and impulsivity. Additionally, these models did not account for BAS facets encompassing the anticipation of reward, i.e...

  • Article
  • Open Access
3 Citations
2,563 Views
33 Pages

10 December 2023

Light and noise are important factors affecting shooting performance, and shooters can exhibit physiological processes that differ from normal shooting when they are subjected to disturbed visual and auditory conditions. The purpose of this study was...

  • Article
  • Open Access
3 Citations
2,445 Views
15 Pages

3 September 2024

Background: Transcranial direct current stimulation (tDCS) is a non-invasive technique known to enhance athletic performance metrics such as vertical jump and lower limb strength. However, it remains unclear whether combining tDCS with the post-activ...

  • Systematic Review
  • Open Access
10 Citations
5,188 Views
61 Pages

Association between the Anatomical Location of Glioblastoma and Its Evaluation with Clinical Considerations: A Systematic Review and Meta-Analysis

  • Juan Jose Valenzuela-Fuenzalida,
  • Laura Moyano-Valarezo,
  • Vicente Silva-Bravo,
  • Daniel Milos-Brandenberg,
  • Mathias Orellana-Donoso,
  • Pablo Nova-Baeza,
  • Alejandra Suazo-Santibáñez,
  • Macarena Rodríguez-Luengo,
  • Gustavo Oyanedel-Amaro and
  • Héctor Gutiérrez Espinoza
  • + 1 author

13 June 2024

Background: Glioblastoma is a primary malignant brain tumor; it is aggressive with a high degree of malignancy and unfavorable prognosis and is the most common type of malignant brain tumor. Glioblastomas can be located in the brain, cerebellum, brai...

  • Article
  • Open Access
6 Citations
2,387 Views
18 Pages

Depression has become one of the most common mental illnesses, causing severe physical and mental harm. To clarify the impact of brain region segmentation on the detection accuracy of moderate-to-severe major depressive disorder (MDD) and identify th...

  • Article
  • Open Access
10 Citations
4,811 Views
12 Pages

This study aimed to answer the questions ‘What are the neural networks and mechanisms involved in visual and kinesthetic motor imagery?’, and ‘Is part of cognitive processing included during visual and kinesthetic motor imagery?&rsq...

  • Article
  • Open Access
1 Citations
2,041 Views
28 Pages

19 April 2024

Stroke recovery is multifaceted and complex. Machine learning approaches have potential to identify patterns of brain activity associated with clinical outcomes, providing new insights into recovery. We aim to use machine learning to characterise the...

  • Article
  • Open Access
13 Citations
8,018 Views
15 Pages

7 August 2013

Neuropsychological and activation studies on the neural correlates of abstract and concrete words have produced contrasting results. The present study explores the anatomical substrates of abstract/concrete words in 22 brain-damaged patients with a s...

  • Article
  • Open Access
14 Citations
5,878 Views
16 Pages

19 March 2020

Inhibitory control is a cognitive process that inhibits a response. It is used in everyday activities, such as driving a motorcycle, driving a car and playing a game. The effect of this process can be compared to the red traffic light in the real wor...

  • Article
  • Open Access
6 Citations
2,752 Views
16 Pages

Altered Cerebro-Cerebellar Effective Connectivity in New-Onset Juvenile Myoclonic Epilepsy

  • Laiyang Ma,
  • Guangyao Liu,
  • Pengfei Zhang,
  • Jun Wang,
  • Wenjing Huang,
  • Yanli Jiang,
  • Yu Zheng,
  • Na Han,
  • Zhe Zhang and
  • Jing Zhang

3 December 2022

(1) Objective: Resting-state fMRI studies have indicated that juvenile myoclonic epilepsy (JME) could cause widespread functional connectivity disruptions between the cerebrum and cerebellum. However, the directed influences or effective connectiviti...

  • Article
  • Open Access
14 Citations
3,914 Views
22 Pages

22 January 2024

Urban landscape parks play a crucial role in providing recreational opportunities for citizens. Different types of landscapes offer varying levels of comfort experiences. However, the assessment of landscape comfort primarily relies on subjective eva...

  • Case Report
  • Open Access
1 Citations
2,576 Views
10 Pages

Psychiatric Illness or Immune Dysfunction—Brain Perfusion Imaging Providing the Answer in a Case of Anti-NMDAR Encephalitis

  • Ines Šiško Markoš,
  • Ivan Blažeković,
  • Vjekoslav Peitl,
  • Tomislav Jukić,
  • Višnja Supanc,
  • Dalibor Karlović and
  • Ana Fröbe

30 September 2022

Background: We investigated the potential use of SPECT quantification in addition to qualitative brain perfusion analysis for the detection of anti-NMDAR encephalitis. The question is how to normalize brain activity to be able to quantitatively detec...

  • Article
  • Open Access
9 Citations
4,108 Views
20 Pages

Alteration of the Intra- and Inter-Lobe Connectivity of the Brain Structural Network in Normal Aging

  • Chi-Wen Jao,
  • Jiann-Horng Yeh,
  • Yu-Te Wu,
  • Li-Ming Lien,
  • Yuh-Feng Tsai,
  • Kuang-En Chu,
  • Chen-Yu Hsiao,
  • Po-Shan Wang and
  • Chi Ieong Lau

28 July 2020

The morphological changes in cortical parcellated regions during aging and whether these atrophies may cause brain structural network intra- and inter-lobe connectivity alterations are subjects that have been minimally explored. In this study, a nove...

  • Article
  • Open Access
2 Citations
2,231 Views
10 Pages

Neuropsychological Functioning in Bilateral versus Unilateral Temporal Lobe Epilepsy

  • Martina Baggio,
  • Alberto Danieli,
  • Cristiano Crescentini,
  • Gian Marco Duma,
  • Martina Da Rold,
  • Sara Baldini,
  • Eric Pascoli,
  • Lisa Antoniazzi,
  • Alec Vestri and
  • Paolo Bonanni
  • + 1 author

29 October 2023

Although relatively specific anatomo-electro-clinical features of temporal lobe epilepsy (TLE) with bilateral ictal involvement (bitemporal epilepsy—BTLE) have been described, differentiating between BTLE and unilateral TLE (UTLE) remains chall...

  • Article
  • Open Access
2 Citations
1,957 Views
28 Pages

28 January 2025

Background/Objectives: Recent theories of the neurocognitive architecture of semantic memory have included a distinction between semantic control in the left inferior frontal gyrus (LIFG) and semantic representation in the left anterior temporal lobe...

  • Case Report
  • Open Access
4 Citations
3,521 Views
8 Pages

8 February 2023

A 27-year-old Han Chinese woman presented with fever, headache, lethargy, and difficulty in expression. Magnetic resonance imaging (MRI) detected extensive hyperintensity of the left-sided frontoparietal, temporal, occipital, and insular cortices via...

  • Article
  • Open Access
22 Citations
8,211 Views
17 Pages

12 September 2013

Potential abnormalities in the structure and function of the temporal lobes have been studied much less in bipolar disorder than in schizophrenia. This may not be justified because language-related symptoms, such as pressured speech and flight of ide...

  • Article
  • Open Access
20 Citations
5,460 Views
15 Pages

Using Fractal Dimension Analysis with the Desikan–Killiany Atlas to Assess the Effects of Normal Aging on Subregional Cortex Alterations in Adulthood

  • Chi-Wen Jao,
  • Chi Ieong Lau,
  • Li-Ming Lien,
  • Yuh-Feng Tsai,
  • Kuang-En Chu,
  • Chen-Yu Hsiao,
  • Jiann-Horng Yeh and
  • Yu-Te Wu

14 January 2021

Normal aging is associated with functional and structural alterations in the human brain. The effects of normal aging and gender on morphological changes in specific regions of the brain are unknown. The fractal dimension (FD) can be a quantitative m...

  • Case Report
  • Open Access
7 Citations
5,921 Views
15 Pages

Apparent False Lateralization of Seizure Onset by Scalp EEG in Temporal Lobe Epilepsy Associated with Cerebral Cavernous Malformation: A Case Report and Overview

  • Mariana Gaviria Carrillo,
  • Jonathan López,
  • Jesús H. Rodríguez Q.,
  • Ivan Gaona,
  • Gloria Ortiz-Guerrero and
  • Mauricio O. Nava-Mesa

24 August 2020

False lateralization of ictal onset by scalp electroencephalogram (EEG) is an infrequent entity that has been reported in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (HS). In these cases, a tendency for rapid sei...

  • Article
  • Open Access
2 Citations
2,973 Views
12 Pages

17 July 2022

Brain asymmetry is associated with handedness and cognitive function, and is also reflected in the shape of endocasts. However, comprehensive quantification of the asymmetry in endocast shapes is limited. Here, we quantify and visualize the variation...

  • Article
  • Open Access
11 Citations
4,901 Views
23 Pages

Speech–Brain Frequency Entrainment of Dyslexia with and without Phonological Deficits

  • Juliana Dushanova,
  • Yordanka Lalova,
  • Antoaneta Kalonkina and
  • Stefan Tsokov

28 November 2020

Developmental dyslexia is a cognitive disorder characterized by difficulties in linguistic processing. Our purpose is to distinguish subtypes of developmental dyslexia by the level of speech–EEG frequency entrainment (δ: 1–4; β...

  • Article
  • Open Access
868 Views
13 Pages

Effects of Dioxin Exposure on Brain Regional Volumes of Fathers from Birth Cohorts in Herbicide-Sprayed and Unsprayed Areas in Vietnam

  • Hai Minh Nguyen,
  • Hoa Thi Vu,
  • Thao Ngoc Pham,
  • Tai Pham-The,
  • Takashi Yokawa,
  • Ryo Matsuda,
  • Masafumi Nakamura,
  • Muneko Nishijo,
  • Yutaro Takahashi and
  • Hisao Nishijo
  • + 2 authors

23 August 2025

We previously reported that the fathers of the Bien Hoa birth cohort in Vietnam showed altered brain regional gray matter volumes, as measured by magnetic resonance imaging, and social anxiety traits associated with perinatal dioxin exposure. In the...

  • Article
  • Open Access
9 Citations
5,300 Views
17 Pages

Recognition of Emotion by Brain Connectivity and Eye Movement

  • Jing Zhang,
  • Sung Park,
  • Ayoung Cho and
  • Mincheol Whang

6 September 2022

Simultaneous activation of brain regions (i.e., brain connection features) is an essential mechanism of brain activity in emotion recognition of visual content. The occipital cortex of the brain is involved in visual processing, but the frontal lobe...

  • Article
  • Open Access
3 Citations
3,641 Views
15 Pages

10 September 2021

Face processing relies on a network of occipito-temporal and frontal brain regions. Temporal regions are heavily involved in looking at and processing emotional faces; however, the contribution of each hemisphere to this process remains under debate....

  • Article
  • Open Access
4 Citations
3,995 Views
18 Pages

Audiovisual Lexical Retrieval Deficits Following Left Hemisphere Stroke

  • Brenda Hanna-Pladdy,
  • Hyun Choi,
  • Brian Herman and
  • Spenser Haffey

28 November 2018

Binding sensory features of multiple modalities of what we hear and see allows formation of a coherent percept to access semantics. Previous work on object naming has focused on visual confrontation naming with limited research in nonverbal auditory...

  • Article
  • Open Access
7 Citations
2,781 Views
11 Pages

Altered Fractional Amplitude of Low-Frequency Fluctuation in Anxious Parkinson’s Disease

  • Peiyao Zhang,
  • Yunpeng Gao,
  • Yingying Hu,
  • Yuan Luo,
  • Lu Wang,
  • Kang Wang,
  • Hong Tian and
  • Miao Jin

Objective: Anxiety symptoms are persistent in Parkinson’s disease (PD), but the underlying neural substrates are still unclear. In the current study, we aimed to explore the underlying neural mechanisms in PD patients with anxiety symptoms. Met...

  • Article
  • Open Access
3 Citations
3,735 Views
14 Pages

Diagnostic Ability of Structural Transcranial Sonography in Patients with Alzheimer’s Disease

  • Daiva Rastenyte,
  • Vaidas Matijosaitis,
  • Ovidijus Laucius,
  • Rymante Gleizniene,
  • Simonas Jesmanas and
  • Kristina Jureniene

The aim of this study was to assess the diagnostic ability of transcranial sonography (TCS) for the evaluation of the medial temporal lobe (MTL) in Alzheimer’s disease (AD). Standard neuropsychological evaluation, TCS and 1.5 T MRI were perform...

  • Article
  • Open Access
1 Citations
1,083 Views
16 Pages

23 September 2025

Major depressive disorder is a mental health condition characterized by ongoing feelings of sadness, trouble focusing or making decisions, and a frequent sense of fatigue or hopelessness that lasts for a prolonged period. If left undiagnosed, it can...

  • Case Report
  • Open Access
1 Citations
3,580 Views
11 Pages

A Forgotten Rare Cause of Unilateral Basal Ganglia Calcinosis Due to Venous Angioma and Complicating Acute Stroke Management: A Case Report

  • Arturs Balodis,
  • Sintija Strautmane,
  • Oskars Zariņš,
  • Kalvis Verzemnieks,
  • Jānis Vētra,
  • Sergejs Pavlovičs,
  • Edgars Naudiņš and
  • Kārlis Kupčs

Background: Unilateral basal ganglia calcinosis (BGC) is a rare radiological finding that can be diagnosed on computed tomography (CT) and magnetic resonance imaging (MRI) but often presents challenges for clinicians and radiologists in determining i...

  • Article
  • Open Access
10 Citations
2,984 Views
11 Pages

Cortical and Subcortical Alterations and Clinical Correlates after Traumatic Brain Injury

  • Qiang Xue,
  • Linbo Wang,
  • Yuanyu Zhao,
  • Wusong Tong,
  • Jiancun Wang,
  • Gaoyi Li,
  • Wei Cheng,
  • Liang Gao and
  • Yan Dong

29 July 2022

Background: Traumatic brain injury (TBI) often results in persistent cognitive impairment and psychiatric symptoms, while lesion location and severity are not consistent with its clinical complaints. Previous studies found cognitive deficits and psyc...

  • Article
  • Open Access
50 Citations
13,139 Views
16 Pages

Reading the Wrong Way with the Right Hemisphere

  • Karen E. Waldie,
  • Charlotte E. Haigh,
  • Gjurgjica Badzakova-Trajkov,
  • Jude Buckley and
  • Ian J. Kirk

17 July 2013

Reading is a complex process, drawing on a variety of brain functions in order to link symbols to words and concepts. The three major brain areas linked to reading and phonological analysis include the left temporoparietal region, the left occipitote...

  • Article
  • Open Access
3 Citations
1,444 Views
23 Pages

Commercial NIRS May Not Detect Hemispheric Regional Disparity in Continuously Measured COx/COx-a: An Exploratory Healthy and Cranial Trauma Time-Series Analysis

  • Amanjyot Singh Sainbhi,
  • Logan Froese,
  • Kevin Y. Stein,
  • Nuray Vakitbilir,
  • Alwyn Gomez,
  • Abrar Islam,
  • Tobias Bergmann,
  • Noah Silvaggio,
  • Mansoor Hayat and
  • Frederick A. Zeiler

Continuous metrics of cerebral autoregulation (CA) assessment have been developed using various multimodal cerebral physiological monitoring devices. However, CA regional disparity remains unclear in states of health and disease. Leveraging existing...

  • Article
  • Open Access
1 Citations
2,000 Views
17 Pages

Parcellation-Based Connectivity Model of the Judgement Core

  • Jorge Hormovas,
  • Nicholas B. Dadario,
  • Si Jie Tang,
  • Peter Nicholas,
  • Vukshitha Dhanaraj,
  • Isabella Young,
  • Stephane Doyen and
  • Michael E. Sughrue

16 September 2023

Judgement is a higher-order brain function utilized in the evaluation process of problem solving. However, heterogeneity in the task methodology based on the many definitions of judgement and its expansive and nuanced applications have prevented the...

  • Article
  • Open Access
18 Citations
8,514 Views
16 Pages

Brain Functional Connectivity Is Modified by a Hypocaloric Mediterranean Diet and Physical Activity in Obese Women

  • Natalia García-Casares,
  • María R. Bernal-López,
  • Nuria Roé-Vellvé,
  • Mario Gutiérrez-Bedmar,
  • Jose C. Fernández-García,
  • Juan A. García-Arnés,
  • José R. Ramos-Rodriguez,
  • Francisco Alfaro,
  • Sonia Santamaria-Fernández and
  • Ricardo Gómez-Huelgas
  • + 6 authors

1 July 2017

Functional magnetic resonance imaging (fMRI) in the resting state has shown altered brain connectivity networks in obese individuals. However, the impact of a Mediterranean diet on cerebral connectivity in obese patients when losing weight has not be...

  • Interesting Images
  • Open Access
1,872 Views
6 Pages

Complex Cerebral Artery Anomaly Rete-like Formation of the Terminal Carotid and Middle Cerebral Arteries with Bilateral A1 Segments Fenestrations

  • Dragoslav Nestorovic,
  • Igor Nikolic,
  • Andrija Savic,
  • Drazen Radanovic,
  • Marko Miletic and
  • Vladimir Cvetic

We present a rare case of a 16-year-old male who was admitted with bilateral tinnitus and subsequently underwent magnetic resonance imaging (MRI) and digital subtraction angiography (DSA) for further evaluation. The left internal carotid (ICA) artery...

  • Article
  • Open Access
5 Citations
2,651 Views
11 Pages

A Study of Differential Resting-State Brain Functional Activity in Males and Females with Recurrent Depressive Disorder

  • Jifei Sun,
  • Shanshan Gao,
  • Yue Ma,
  • Chunlei Guo,
  • Zhongming Du,
  • Yi Luo,
  • Limei Chen,
  • Zhi Wang,
  • Xiaojiao Li and
  • Jiliang Fang
  • + 4 authors

6 November 2022

In this study, we observed the sex differences in functional brain activity in patients with recurrent depressive disorder (RDE) and assessed the correlation between abnormal functional brain activity changes and clinical symptoms. A total of 40 pati...

  • Article
  • Open Access
19 Citations
3,674 Views
16 Pages

4 December 2021

Aging is accompanied by frontal lobe and non-dominant hemisphere recruitment that supports executive functioning, such as inhibitory control, which is crucial to all cognitive functions. However, the spatio-temporal sequence of processing underlying...

  • Article
  • Open Access
12 Citations
7,175 Views
8 Pages

Temporal Horn Enlargements Predict Secondary Hydrocephalus Diagnosis Earlier than Evans’ Index

  • Paolo Missori,
  • Sergio Paolini,
  • Simone Peschillo,
  • Cristina Mancarella,
  • Anthony Kevin Scafa,
  • Emanuela Rastelli,
  • Stefano Martini,
  • Francesco Fattapposta and
  • Antonio Currà

25 May 2022

The aim of this study was to identify early radiological signs of secondary hydrocephalus. We retrieved neuroradiological data from scans performed at various times in patients who underwent surgery for secondary hydrocephalus due to severe traumatic...

  • Article
  • Open Access
1,718 Views
14 Pages

Linking Memory Impairment to Structural Connectivity in Extrahippocampal Temporal Lobe Epilepsy Surgery

  • Niels Alexander Foit,
  • Karin Gau,
  • Alexander Rau,
  • Horst Urbach,
  • Jürgen Beck and
  • Andreas Schulze-Bonhage

Objective: Temporal lobe epilepsy (TLE) constitutes the most common drug-refractory epilepsy syndrome. Tailored approaches are required, as TLE originates from extrahippocampal lesions in about one-quarter of surgical candidates. Despite high success...

  • Systematic Review
  • Open Access
2 Citations
3,096 Views
10 Pages

Adult-Onset Pilocytic Astrocytoma Predilecting Temporal Lobe: A Brief Review

  • Nazmin Ahmed,
  • Gianluca Ferini,
  • Kanak Kanti Barua,
  • Rathin Halder,
  • Sudip Barua,
  • Stefano Priola,
  • Ottavio Tomasi,
  • Giuseppe Emmanuele Umana,
  • Nathan A. Shlobin and
  • Bipin Chaurasia
  • + 2 authors

21 June 2022

(1) Introduction: Adult-onset pilocytic astrocytoma (APA) accounts for only 1.5% of all brain tumors, and studies regarding APA are limited. This review is focused on the history, clinical course, cytogenetics, neuroimaging features, management, and...

  • Article
  • Open Access
9 Citations
3,925 Views
20 Pages

Engagement of Language and Domain General Networks during Word Monitoring in a Native and Unknown Language

  • Kelly R. Cotosck,
  • Jed A. Meltzer,
  • Mariana P. Nucci,
  • Katerina Lukasova,
  • Letícia L. Mansur and
  • Edson Amaro

13 August 2021

Functional neuroimaging studies have highlighted the roles of three networks in processing language, all of which are typically left-lateralized: a ventral stream involved in semantics, a dorsal stream involved in phonology and speech production, and...

  • Article
  • Open Access
450 Views
14 Pages

The Spatial Signature of Glioblastoma: A Statistical Re-Assessment of Anatomical Distribution Based on Methylation Subtypes

  • Tim Herrmann,
  • Claire Delbridge,
  • Michael Griessmair,
  • Julian Canisius,
  • Meike Mitsdoerffer,
  • Denise Bernhardt,
  • Isabel C. Hostettler,
  • Chiara Negwer,
  • Igor Yakushev and
  • Marie-Christin Metz
  • + 5 authors

19 January 2026

Precise molecular characterization of glioblastoma (GB) is fundamental for accurate risk stratification and therapeutic planning. DNA methylation profiling reliably identifies key molecular features, including O(6)-methylguanine-DNA methyltransferase...

  • Case Report
  • Open Access
85 Citations
15,285 Views
10 Pages

A Rare Case of Cerebral Venous Thrombosis and Disseminated Intravascular Coagulation Temporally Associated to the COVID-19 Vaccine Administration

  • Vincenzo D’Agostino,
  • Ferdinando Caranci,
  • Alberto Negro,
  • Valeria Piscitelli,
  • Bernardino Tuccillo,
  • Fabrizio Fasano,
  • Giovanni Sirabella,
  • Ines Marano,
  • Vincenza Granata and
  • Roberto Grassi
  • + 2 authors

8 April 2021

Globally, at the time of writing (20 March 2021), 121.759.109 confirmed COVID-19 cases have been reported to the WHO, including 2.690.731 deaths. Globally, on 18 March 2021, a total of 364.184.603 vaccine doses have been administered. In Italy, 3.306...

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