Search Results (914)

The bioeconomy has been discussed as a key strategy for addressing sustainability challenges, particularly regarding the transition from fossil-based to bio-based systems, in numerous national and supranational strategies and policy documents related to the bioeconomy. However, public understanding of and engagement with the bioeconomy remains limited. This is partly due to the bias of many bioeconomy strategies and policy documents towards technological solutions that tend to overlook the social, normative, and transformative dimensions of systemic change as well as the necessary knowledge. This opinion paper explores the potential of narratives as a means of communicating bioeconomy research in public policy, with the aim of addressing the communication gap between science, policy, and society. When applied in responsible and nuanced ways that acknowledge their embeddedness and context, bioeconomy (policy) narratives can support sensemaking for science communication, improve public understanding, facilitate stakeholder engagement and behavioural change. We argue that such narrative approaches can help to create narrative ‘boundary objects’ that can support more inclusive and participatory processes, enabling the co-creation of transformative knowledge for bioeconomy transitions with stakeholders as active participants. In summary, we highlight several opportunities, as well as limitations and implications, that could inform future work on bioeconomy narratives. Full article

Background/Objectives: Vaccination uptake in Ethiopia is deeply shaped by gender norms, with women serving as primary caregivers but often limited by low autonomy, while men typically control household decisions but remain less engaged in child health. This study examines gendered influences on vaccine hesitancy and acceptance to inform future strategies. Methods: A community-based cross-sectional mixed-methods study was conducted in four regions of Ethiopia (Amhara, Oromia, Afar, and Tigray). Quantitative data were collected from 992 caregivers through multistage stratified sampling procedure, whereas qualitative data were collected from 26 in-depth interviews, 24 exit interviews and 11 key informant interviews and were analyzed thematically guided by the WHO Behavioural and Social Drivers framework. Multivariable logistic regression was conducted to determine the associations. Results: The result highlighted that the proportion of caregivers who reported willingness to vaccinate their child with all recommended vaccines was high (93.5%) and more likely among those with higher education, family support, religious support, and frequency of health worker contact. However, 51.1% of caregivers displayed some degree of vaccine hesitancy, with higher prevalence among males. Hesitancy was linked to traditional beliefs and norms that assign vaccination responsibility to mothers, urban residence, and being employed, while secondary education, family support, and religious support were protective. While acceptance is high, hesitancy persists. Gender roles, education, social support, and health worker engagement influence immunization outcomes. Conclusions: The study highlighted that expanding immunization across all age groups and reducing persistent hesitancy requires a shift toward gender-responsive strategies including integrating a gender perspective into the immunization programs that address traditional norms and misinformation. Full article

This paper examines the current implementation of Artificial Intelligence (AI) in higher education and its implications for inclusivity, particularly for minority groups. Using a rapid review methodology, it synthesises academic literature, policy reports, and case studies to explore how AI is reshaping educational environments. The analysis reveals that although AI technologies—such as adaptive learning systems, intelligent tutoring, and predictive analytics—are increasingly adopted, their primary aim remains institutional efficiency rather than fostering equity. Initiatives explicitly designed to support underrepresented students are rare, exposing a gap between technological innovation and inclusive practice. The study identifies key barriers, including socioeconomic inequality, cultural and linguistic bias, and limited institutional capacity, which are often compounded by AI systems trained on non-representative data. While isolated case studies demonstrate that (e.g., culturally) responsive AI can enhance educational access for marginalised learners, these remain exceptions rather than norms. The findings suggest that without deliberate efforts to embed inclusivity in AI design and deployment, existing inequalities may be perpetuated or worsened. The paper concludes that realising AI’s inclusive potential requires ethical frameworks, diverse development teams, and equitable access strategies. It calls for future empirical research focused on practical interventions that reduce disparities, contributing to a more just and inclusive higher education landscape. Full article

(1) Introduction: Arab American (ArA) men have higher smoking rates than the general population, driven by cultural norms. Culturally tailored interventions that incorporate ArA cultural, linguistic, and social contexts are essential for addressing tobacco use and promoting health equity. This study aimed to evaluate a culturally tailored smoking cessation intervention for ArA men living in North Carolina. (2) Methods: This pilot study employed a one-group pre- and post-test design to evaluate program effectiveness within financial and time constraints. The participants completed questionnaires and Carbon monoxide measurements and were provided with Nicotine Replacement therapy. (3) Results: The study found that participants experienced anxiety and stress when delaying their first morning cigarette, which hindered cessation. Although smoking was reduced, relapse was common, highlighting the need for personalized support, especially for those with higher nicotine dependence. While telephone Motivational Interviewing helped reduce anxiety, it was insufficient for complete cessation, underscoring the need for tailored approaches addressing both psychological and physical factors. (4) Conclusions: The study suggests that culturally tailored telephone counseling did not show promise as a smoking cessation strategy for Arab Americans in North Carolina due to low participation. The sample size is really too small to test the efficacy of the intervention itself. It seems to have been more successful in another state. Future efforts should address cultural factors, emerging nicotine products, and expanded research. The project is significant for addressing health disparities among Arab Americans by integrating culturally relevant smoking cessation strategies with evidence-based methods like Nicotine Replacement Therapy. Full article

Violence against women and girls (VAWG) remains a critical problem within Brazilian higher education institutions, where deep-rooted cultural norms and institutional shortcomings continue to foster unsafe environments for female students. Although national and international bodies have raised concerns, few studies have thoroughly examined the layered causes of VAWG in academic settings using comprehensive analytical methods. This study aims to explore the causal factors of VAWG within Brazilian universities by applying a structured survey and analyzing the responses using the Fuzzy Synthetic Evaluation (FSE) approach. This method allows for a nuanced interpretation of the collected data by assigning weighted values to various contributing factors. The research assessed five major dimensions—individual, interpersonal, institutional, community and societal causal factors. The findings reveal that societal and institutional causes significantly contribute to VAWG, while individual factors play a comparatively minor role. These insights point to the structural and systemic nature of VAWG in academic settings, emphasizing the need for broad reforms. Based on the results, practical recommendations, including cultural reorientation, stricter institutional policies, and gender-sensitive training are recommended. By applying FSE in this context, the study offers a novel approach to evaluating and addressing gender-based violence (GBV) in higher education, contributing to a valuable model for future research and institutional policymaking. The results offer critical insights that can guide interventions to foster safer and more inclusive university environments in Brazil. Full article

This study proposes a methodology for conducting computational simulations of pathological gait. The literature shows a consensus that biomechanical models for gait analysis should be formulated as control problems. To achieve this, it is common practice to guide the solution using kinematic or kinetic data to prevent temporal instability. The aim of this study is to implement a biomechanical model of the Charcot–Marie–Tooth disease in OpenSim software that enables more comprehensive simulations, which may in future involve the musculoskeletal system of patient and predictive studies. In this way, it will be possible to design specific active assistive devices tailored to each patient. Experimental gait data from six Charcot–Marie–Tooth patients were used. The dataset comprises three-dimensional trajectories of reflective markers placed according to the Davis-Heel protocol. The acquired data allowed a patient-specific adjustment of the biomechanical model. The inverse kinematic was solved, and the results were validated by comparing them with those obtained using the commercial BTS Bioengineering^® software. The results show a strong alignment in ankle kinematics between the OpenSim model and the data generated by BTS Bioengineering^®. Additionally, the kinematic results have been compared with normative curves, allowing the identification of potential areas for intervention using active assistive devices aimed at improving movement patterns of patients. Full article

Media shape and reflect social imaginaries, influencing collective beliefs, norms, and aspirations. Video games and films frequently depict themes like urbanization, dystopian futures, and resource-driven expansion, often envisioning humanity colonizing new planets after depleting Earth’s resources. Such narratives risk reinforcing exploitative attitudes toward the environment, extending them to new frontiers. Research has shown that media, especially video games, influence societal perceptions and shape future possibilities. While largely reflecting anthropocentric worldviews, these media also have the potential to promote ecocentric perspectives. In the context of biodiversity loss and planetary imbalance, media’s role in fostering non-anthropocentric values is crucial. This study introduces the Non-Anthropocentric Media Evaluation Questionnaire (NAMEQ), a tool designed to help media producers assess whether their work aligns with ecocentric principles, and to support academic researchers and students in the study and analysis of media from a biocentric perspective. Applying this framework to 138 widely distributed video games and films reveals a strong dominance of anthropocentric narratives. While some works incorporate ecocentric themes, they remain inconsistent. The findings underscore the need for a more deliberate and coherent representation of bio-centric values in media, advocating for a shift in cultural narratives toward perspectives that recognize and respect the intrinsic value of the non-human world. Full article

Health systems function optimally when accountability principles, legal frameworks, and governance processes are clearly defined, understood, and implemented. Together these elements set norms, standards, and systems for the practice of health professionals, facilities, products, and the provision of quality and safe care. Ghana, like other countries, has these elements in place but could be more effective. When the system fails, the consequences of a lack of accountability are widespread, significant, and impact the poor and vulnerable the hardest. Achieving accountability for the legal and social expectation of high-quality, safe healthcare is an ongoing challenge, for every country, not just Ghana. Hence, a key dual question arises: within Ghana, how can health system accountability be enhanced through examining legal frameworks and their implementation? The following six key elements are identified to promote accountability in health systems: establish and implement effective healthcare governance arrangements; capacity development, understanding, and delineation of stakeholder roles and responsibilities; appropriate financing and resourcing; establishing and maintaining effective management of required infrastructure; undertaking measurement for accountability; and focusing on people-centered care. A clear focus on these six elements enables the delivery of equitable, high-quality, safe care for the population and a better future for all. Full article

Several European courts have vested mitigation obligations with a hierarchically higher legal rank than ordinary state action. They construe these obligations from human rights in combination with international commitments and climate science. This phenomenon is here called ‘climate constitutionalisation’. In addition, we see an increasing escalation of climate cases to the European Court of Human Rights (ECtHR) and we now have the advisory opinion of the International Court of Justice (ICJ). Climate constitutionalisation in Europe is an incremental process of replication and reiteration. It can only be understood by studying the developing body of national case law in the context European and international law. Studying general emission reduction cases against states in Europe, this paper traces how non-enforceable legal norms, political commitments, and climate science are used to interpret binding and enforceable human rights norms. It reflects on the present and future consequences of the ECtHR’s decision in KlimaSeniorinnen and ICJ’s Advisory Opinion on climate obligations. The paper argues that Europe’s multilayered legal and judicial landscape strengthens climate constitutionalisation and herewith deepens the fault line between the judiciary and the elected institutions. Europe’s openness towards international law facilitates this process. The paper then offers tentative normative justifications for this process. Full article

The proliferation of diverse multi-stakeholder partnering arrangements that seek to achieve the 2030 Agenda for Sustainable Development has prompted calls for overarching standards to enhance their governance, legitimacy and effectiveness. This conceptual article critically examines the limitations of applying universal partnership standards across complex and context-sensitive collaborative arrangements. Drawing on a purposive sampling of approximately 115 academic, policy-oriented and practitioner sources, identified through targeted database searches, we explore the historical development of sustainability-related partnership norms and identify some of the tensions in their alignment with socio-historic, institutional and relational dynamics. We examine the concept of partnership meta-governance as a way of both ensuring and enabling effective collaborative initiatives working to meet the targets of the 2030 Agenda’s 17 Sustainable Development Goals. Using a methodology that combines conceptual analysis with practitioner-tested support mechanisms, we propose a principles-based approach to enrich the enabling dimension of partnership meta-governance by privileging contextual responsiveness, co-creation and relational values over prescriptive compliance. This approach seeks to reinforce the transformational intent of the 2030 Agenda by offering a foundation for more inclusive and adaptive collaboration that supports the long-term aspirations of the United Nations’ Pact for the Future. Full article

The aim of this paper is to show that sustainable tourism, the widely accepted benchmark for the present and future responsible tourism industry is, and will continue to be, a myth. The paper takes the form of a review essay and relies on discussions of concepts, comparisons, and examples rather than field research and empirical data to define the problem and draw conclusions. We use the folkloric myth of Plutus, the god of wealth and abundance, to underscore two moral themes. The first is that wealth is blind, and second that seeking wealth and abundance is an entrenched aspect of human nature, with greed (avarice) consistently destabilizing societal improvements. Science shows us what the problems are (e.g., climate change), while ethics tell us how to address these problems. However, it seems that we still cannot find our way to a sustainable tourism future. What is playing out in the theatre of sustainable tourism, therefore, is far from a comedy and much more like a tragedy, as tourism in its current forms has become too much of a good thing, rendering “sustainable” a meaningless term. Overtourism, overdevelopment, disparities, and injustices are now the norm in the maelstrom of global tourism, with no palpable end in sight. Full article

(1) This study aims to quantify differences between platforms and countries by comparing Hilton’s ratings on Booking.com and Google.com in the V4 countries. (2) Data were collected directly from Booking.com and Google.com for selected Hilton hotels. Descriptive statistics were used to process and analyze the data, and a paired Student’s T-test was used to compare standard deviations between platforms. (3) The analysis showed that these differences can be applied not only to subjective preferences but also to sociotechnical devices, including cultural platforms and their associated norms and user expectations. Additionally, factors such as price, food quality, and atmosphere were shown to influence overall guest satisfaction, with ratings approximately indicating satisfaction or dissatisfaction. (4) From a practical perspective, these insights can help hotel managers optimize their online communication strategy, tailor content to different platforms, and manage their reputation more effectively. Overall, the findings highlight that effectively managing online reviews is key to establishing trust, increasing satisfaction, and ensuring the long-term success of the Hilton brand in diverse sociocultural contexts. Future research should focus on sociotechnical aspects and the impact of seasonal or marketing campaigns on reviews to gain a more comprehensive understanding of the dynamics of online reviews in the hospitality industry. Full article

The integration of nanotechnology into drug repurposing strategies is redefining the development landscape for diagnostic, therapeutic, and theranostic agents. In radiopharmacy, nanoplatforms are increasingly being explored to enhance or extend the use of existing radiopharmaceuticals, complementing earlier applications in other biomedical fields. Many of these nanoplatforms evolve into multifunctional systems by incorporating additional imaging modalities (e.g., MRI, fluorescence) or non-radioactive therapies (e.g., photodynamic therapy, chemotherapy). These hybrid constructs often emerge from the reformulation, repositioning, or revival of previously approved or abandoned compounds, generating entities with novel pharmacological, pharmacokinetic, and biodistribution profiles. However, their translational potential faces significant regulatory hurdles. Existing frameworks—typically designed for single-modality drugs or devices—struggle to accommodate the combined complexity of nanoengineering, radioactive components, and integrated functionalities. This review examines how these systems challenge current norms in classification, safety assessment, preclinical modeling, and regulatory coordination. It also addresses emerging concerns around digital adjuncts such as AI-assisted dosimetry and software-based therapy planning. Finally, the article outlines international initiatives aimed at closing regulatory gaps and provides future directions for building harmonized, risk-adapted frameworks that support innovation while ensuring safety and efficacy. Full article

Background: This study aims to establish standardized reference values for myocardial T1 and T2 relaxation times in a clinically and imaging-defined real-world patient cohort, evaluating their variability in relation to age, sex, and comorbidities. By identifying key physiological and pathological influences, this investigation seeks to enhance CMR-based myocardial mapping for improved differentiation between normal and pathological myocardial conditions. Methods: This retrospective observational study analyzed T1 and T2 relaxation times using CMR at 1.5 Tesla in a cohort of 491 subjects. T1 and T2 times were measured using MOLLI and GRASE sequences, and statistical analyses assessed intra- and interindividual variations, including the influence of age, sex, and comorbidities, to establish reference values and improve myocardial tissue characterization. Results: T1 and T2 relaxation times were analyzed in 291 and 200 participants, respectively. The mean global T1 time was 1004.7 ± 49.8 ms, with no significant differences between age groups (p = 0.81) or sexes (p = 0.58). However, atrial fibrillation (AF) and mitral regurgitation (MR) were associated with significantly prolonged T1 times (p < 0.05). The mean global T2 time was 67.4 ± 8.6 ms, with age-related prolongation (p < 0.05), but no sex differences (p = 0.46). Comorbidities did not significantly influence T2 times, except for NYHA Class III–IV patients, who exhibited prolonged T2 values (p < 0.05). Conclusions: Standardized T1 and T2 reference values are essential to improve diagnostic accuracy and risk stratification in CMR-based myocardial tissue characterization. Future research should focus on multicenter validation, AI-driven analysis, and the development of age- and comorbidity-adjusted normative databases to enhance individualized cardiovascular care. Full article

This study focuses on firefighters’ relationship with different types of change in their profession and what barriers and facilitators might contribute to how they respond. Informed by the Force Field analysis of change, interviews were conducted to better understand what specific barriers and facilitators contribute to their views on types of change and the level of influence they carried. Twenty-five interviews were conducted with firefighters from a variety of backgrounds, including different ages, genders, ranks, and experience levels for both career and volunteer firefighters. Thematic analysis identified different responses to four common rationales that helped to explain the acceptance or dismissal of changes. These were as follows: (1) openness or apprehension towards change; (2) the results of a cost–benefit analysis that considered financial and manpower limits, perceived legitimacy of the problem, and efficacy of the solution; (3) reference to past experiences with changes that had failed or succeeded; and (4) trusted messengers that respected the chain of command were preferred. These themes are applicable across multiple types of changes, including technological and cultural adaptation. However, they also reveal challenges that may emerge due to friction with firefighters’ professional identities and traditional masculine norms. The patterns identified here can help to inform future efforts to implement changes and to anticipate likely points of friction or motivation that can be leveraged. Full article