Search Results (14)

This study proposes a couple of analytical solutions that characterize the anisotropic dense celestial bodies within the Rastall-Rainbow theoretical framework. The analysis assumes a static spherically symmetric matter distribution and derives the corresponding modified field equations. By utilizing well-established radial metric functions and merging them with the two principal pressures, we obtain differential equations related to the time component. Subsequently, we perform the integration of these equations to determine the remaining geometric quantity that encompasses various integration constants. The proposed interior solutions are then matched with the Schwarzschild exterior metric at the boundary of the compact object, facilitating the determination of the constants. Additionally, the incorporation of the non-minimal coupling parameter into these constants is accomplished by enforcing the null radial pressure at the boundary. Afterwards, we rigorously examine the physical characteristics and critical stability conditions of the formulated models under observational data from two pulsars, say 4U 1820-30 and LMC X-4. It is concluded that our models are well-aligned with essential criteria required to ensure the physical viability of stellar structures, subject to specific parametric values. Full article

The contrast between languages such as Italian that allow subjects of tensed sentences to be null (i.e., pro-drop languages) and those like French that do not (i.e., non-pro-drop languages) is a classic issue for comparative syntactic research. Nevertheless, while several studies have been dedicated to pro-drop languages, distinguishing across different types, subject omission in non-pro-drop languages is generally misjudged as a marginal or substandard phenomenon. However, a more careful examination reveals that the occurrence of Null Subjects (NSs) in non-pro-drop languages is associated with distinct semantic and discourse imports. Based on a systematic corpus analysis, this work will confirm that NSs do occur in Colloquial French, especially in the case of expletive subjects. Furthermore, evidence will be provided for a crucial connection between subject omission, expletive types, and the morpho-syntactic categories of person/number for argument pronouns. This pilot work can thus open new perspectives for future research. Full article

This article explores a learning model for acquiring a variety of null and non-null-subject languages (i.e., consistent, partial, semi and non-null-subject languages). This model builds upon a version of the Null Subject Parameter(s) based on the “Borer-Chomsky Conjecture” (BCC), which assumes that the presence or absence of a D(definiteness)-feature in different functional heads, together with EPP (Extended projection principle) related features, account for the distributions of null subjects in a complex typology of (non-)null-subject languages. This BCC-based learning model assumes the hypothesis that children, in order to learn the pattern of null subjects in their language, need to look at the morphology of functional elements. By reviewing acquisition studies, I examine whether the model is compatible with the data. I argue that there is no evidence of parameter missetting in any of the languages examined, and that children’s early sensitivity to functional elements suggests that the BCC-based learning model is a suitable theory for the acquisition of null subjects. Full article

Cognitive science has demonstrated that multilinguals (including children) show a cognitive advantage over monolinguals. Linguistics has provided evidence that multilinguals (including children) are able to successfully separate their lexicons and grammars and negotiate multilingual environments. Apart from these achievements, linguistics has generally failed to demonstrate a multilingual advantage related to the multilingual’s linguistic proficiency. The present article summarizes the current literature, which shows that there are first indications of an acceleration effect in multilingual children. This effect is discernable if the languages radically differ, if the child uses a ‘weak’ language (often a minority language), if the child acquires more than two languages from birth, and if contact with the language exhibiting the acceleration effect is delayed until kindergarten age. This kind of acceleration effect represents an explanation gap under current theorizing in cognitive science and linguistics, and calls for a new language acquisition theory, a best-of-breed solution for further research in language acquisition. A_AiMLL (Acquisition Advantages in MultiLingual Learners) combines cognitive and linguistic aspects with a threshold theory. It is claimed here that the multilingual child learns from two cognitive acquisition strategies. One is fed by grammatical features, and requires the child to (re-)use already acquired knowledge by generalizing to new domains. The other strategy enables the child to consider rejected alternatives of earlier decisions in one language, for use in the other language. An acceleration effect related to the multilingual’s linguistic proficiency is indicative of the success of both strategies. The success of the strategies is argued to be related to a threshold of language usage from a quantitative or a qualitative perspective. Full article

Polychlorinated biphenyls (PCBs) are persistent organic pollutants and endocrine disruptors that have been implicated in potential damage to human semen. However, the studies conducted so far provide contrasting results. Our study aimed to investigate the associations between PCB serum and semen levels and semen quality in high school and university students living in a highly PCB-polluted area of Italy. Subjects with a normal body mass index who did not make daily use of tobacco, alcohol, drugs, or medication were selected. All participants provided a fasting blood and a semen sample. Gas chromatography-mass spectrometry was used to determine the concentrations of 26 PCB congeners. The concentrations of PCB functional groups and total PCBs were also computed. A total of 143 subjects (median age 20, range 18–22 years) were enrolled. The median total PCB concentrations were 3.85 ng/mL (range 3.43–4.56 ng/mL) and 0.29 ng/mL (range 0.26–0.32 ng/mL) in serum and semen, respectively. The analysis of the associations between sperm PCB concentration and semen parameters showed (a) negative associations between some PCB congeners, functional groups and total PCBs and sperm total motility; (b) negative associations of total PCBs with sperm normal morphology; and (c) no association of PCBs with sperm concentration. Subjects at the highest quartile of semen total PCB concentration had 19% and 23% mean reductions in total motility and normal morphology, respectively, compared to those at the lowest quartile. The analysis of the associations of serum PCB levels with sperm parameters yielded null or mixed (some positive, other negative) results. In conclusion, the present study provides evidence of a negative effect of some PCB congeners and total PCBs in semen on sperm motility and normal morphology. However, the associations between the concentration of serum and semen PCB congeners and functional groups and sperm quality parameters were inconsistent. Full article

L-citrulline serves as a nitric oxide precursor with the potential to increase blood flow and improve resistance exercise performance, yet more research is needed to examine its ergogenic potential. To examine the effect of L-citrulline supplementation on resistance exercise performance, muscle oxygenation, and the subjective perception of effort, energy, focus, fatigue, and muscle pump, eighteen resistance-trained men (n = 11) and women (n = 7) (21.4 ± 1.8 years; 172.3 ± 7.5 cm; 76.9 ± 10.8 kg) were randomly assigned for supplementation with 8 g of L-citrulline (CIT) or a placebo (PL) in a cross-over fashion one hour prior to testing. Participants completed an isometric mid-thigh pull test (IMTP), a ballistic bench press protocol [two sets of two repetitions at 75% 1-repetition maximum (1 RM) with maximum ballistic intent], and a strength-endurance bench press protocol [five repetition-maximum sets at 75% 1RM]. Barbell velocity and power were measured via a linear position transducer during the ballistic protocol, while the repetitions completed, volume load and muscle oxygenation were quantified during the strength-endurance protocol. Subjective measures were assessed at the baseline and immediately pre- and post-exercise. Repeated measures of the analysis of variance and Bayesian equivalents revealed no significant interactions, providing evidence favoring the null hypothesis (BF10 < 1) for IMTP (PL 497.5 ± 133.6 vs. CIT 492.5 ± 129.4 N), barbell velocity, and power, and repetitions completed (PL 36.7 ± 7.2 vs. CIT 36.9 ± 8.1 repetitions). There were also no significant interactions for muscle oxygenation parameters or subjective measures except perceived fatigue. Women reported greater fatigue across all time points compared to men (~1.88 au, p = 0.045, BF10 = 0.2). The results indicate that a single 8 g dose of L-citrulline did not enhance isometric force production, muscle endurance, or muscle oxygenation parameters during the protocol implemented in this study. Full article

Lexical expletives can be divided into two main classes: (i) CP expletives required by the V2 constraint and, hence, by the necessity to lexicalize the position on the left of the inflected verb and (ii) TP expletives connected with the negative value of the pro-drop parameter and, therefore, with the necessity to lexicalize the ’structural‘ subject position, specifically, [Spec, TP]. The latter can, in turn, be divided into two subclasses: impersonal subjects and positional expletives, which occur with postverbal/low subjects and extraposed subject clauses. While CP expletives only appear in Germanic varieties that maintain V2, the subclassification of TP expletives yields interesting results when comparing Cimbrian and the Venetan varieties in Nord-East Italy, where the gradual disappearance of the positional expletive in free inversion structures and the residual maintenance of impersonal subjects from North to South along the Adige River confirms the distinction between two classes of subject expletives; furthermore, the resilience of impersonal subjects and their distribution in the northwestern part of the area under consideration sheds light on the role of language contact which is confirmed along the same axis—but crucially in the opposite direction—by the increasing employment of cleft constructions in WH-clauses replacing enclisis (i.e.,: pronominal subject inversion with the finite verb). Full article

Bland–Altman agreement analysis has gained widespread application across disciplines, last but not least in health sciences, since its inception in the 1980s. Bayesian analysis has been on the rise due to increased computational power over time, and Alari, Kim, and Wand have put Bland–Altman Limits of Agreement in a Bayesian framework (Meas. Phys. Educ. Exerc. Sci. 2021, 25, 137–148). We contrasted the prediction of a single future observation and the estimation of the Limits of Agreement from the frequentist and a Bayesian perspective by analyzing interrater data of two sequentially conducted, preclinical studies. The estimation of the Limits of Agreement θ₁ and θ₂ has wider applicability than the prediction of single future differences. While a frequentist confidence interval represents a range of nonrejectable values for null hypothesis significance testing of H₀: θ₁ ≤ −δ or θ₂ ≥ δ against H₁: θ₁ > −δ and θ₂ < δ, with a predefined benchmark value δ, Bayesian analysis allows for direct interpretation of both the posterior probability of the alternative hypothesis and the likelihood of parameter values. We discuss group-sequential testing and nonparametric alternatives briefly. Frequentist simplicity does not beat Bayesian interpretability due to improved computational resources, but the elicitation and implementation of prior information demand caution. Accounting for clustered data (e.g., repeated measurements per subject) is well-established in frequentist, but not yet in Bayesian Bland–Altman analysis. Full article

This study aimed to evaluate the impact of Helicobacter pylori (H. pylori) infection on metabolic parameters in a longitudinal follow-up manner. From August 2013 to August 2019, a community-based prospective study of H. pylori and metabolic syndrome (MetS) was performed in the northeastern region of Taiwan. A total of 1865 subjects were divided into four groups according to the serial results of urea breath test (UBT): new H. pylori infection (group 1, n = 41), null H. pylori infection (group 2, n = 897), loss of H. pylori infection (group 3, n = 369), and persistent H. pylori infection (group 4, n = 558). When comparing the subjects between groups 1 and 2, HBA1c was associated with a new H. pylori infection. Body mass index (BMI) was associated with a loss of H. pylori when comparing subjects between groups 3 and 4. Elevated HBA1c and high-density lipoprotein (HDL) levels but lower values of cholesterol and white blood cells (WBCs) were found during serial analyses within group 3. Conclusively, HBA1c was associated with a new H. pylori infection. BMI was associated with H. pylori loss. Increased HBA1c and HDL values but decreased values of cholesterol and WBC were associated with a loss of H. pylori infection. Full article

In our paper, we deal with the Germanic–Romance language contact, focusing on Cimbrian, a Germanic minority language spoken in Northern Italy. Specifically, we focus on the violation of the well-known that-trace filter, as it appears to be an interesting case of the superficial convergence that we ascribe to the status of T, which is either too rich (model language) or too weak (replica language) to represent a viable landing site for subject extraction. Full article

The study investigated the influence of genetic polymorphisms of the enzymes for DNA repair and detoxification of reactive intermediates on spontaneous and bleomycin-induced (BLM) genotoxic damage in 43 workers exposed to very low doses of ionizing radiation (IR) (mean cumulative dose 5.31 mSv) and 43 subjects with no occupational exposure to IR (controls). In all the subjects examined, the frequency of chromosome aberrations (CAs) and micronuclei (MN), both spontaneous and BLM-induced, the Comet assay parameters (tail intensity), the genotypic variants of the DNA repair enzymes XRCC1 (Arg194Trp, Arg280His, Arg399Gln), XRCC3 (Thr241Met), XPD (Lys751Gln), and of the detoxification enzymes GSTM1 and GSTT1 (null genotype) and BLMH (A1450G) were determined. Among the biomarkers considered, only the frequency of total CAs (p < 0.05), and in particular of chromosome breaks (p < 0.01), was found to be significantly higher in the exposed workers than the controls. The frequency of spontaneous MN was higher in subjects with at least one allelic variant in XRCC1 than in carriers of the wild-type, but again only in exposed workers (p = 0.046). Linear regression analysis showed a positive dependency of the frequency of spontaneous chromosome breaks on occupational exposure, and a dependency of the frequency of BLM-induced MN negative on occupational exposure and positive on alcohol consumption and the null GSTM1 genotype. In conclusion, the frequency of chromosome breaks seems to be a useful cytogenetic biomarker for exposure to very low doses of IR, while only the combined effect of different gene variants or genetic, occupational, and lifestyle habits factors seems to be able to modulate the genotoxic effect of very low doses of IR. Full article

The purpose of this study is to investigate the value-relevance of corporate sustainability disclosure through integrated reporting. Sustainability disclosure is subject to managers’ discretion. Besides, it is often hardly verifiable. In this respect, integrated reporting could provide the means for a verifiable disclosure, otherwise, in the jargon of game theory, it could be considered as a cheap talk. This paper investigates which of these hypotheses is most likely to occur in reality. In order to do this, a simple theoretical framework is introduced, where sustainability of corporate performances is modelled as a tail-risk for shareholders. Costless signaling games (cheap talk) and persuasion games are reviewed within this context, in order to derive competing theories of sustainability disclosure’s value relevance through integrated reporting. These alternative theories are tested empirically consistent with the theoretical framework presented, in order to identify key-parameters. In this respect, a systematic textual analysis (artificial intelligence) of integrated reports was employed as to build a synthetic measure of sustainability disclosure. The application of this methodology on a sample of European listed companies showed that sustainability disclosure through integrated reporting has no effect on market-valuations, confirming the null hypothesis of integrated reporting resulting in a cheap talk’s babbling equilibrium. Full article

Gene-environment (GE) interaction has important implications in the etiology of complex diseases that are caused by a combination of genetic factors and environment variables. Several authors have developed GE analysis in the context of independent subjects or longitudinal data using a gene-set. In this paper, we propose to analyze GE interaction for discrete and continuous phenotypes in family studies by incorporating the relatedness among the relatives for each family into a generalized linear mixed model (GLMM) and by using a gene-based variance component test. In addition, we deal with collinearity problems arising from linkage disequilibrium among single nucleotide polymorphisms (SNPs) by considering their coefficients as random effects under the null model estimation. We show that the best linear unbiased predictor (BLUP) of such random effects in the GLMM is equivalent to the ridge regression estimator. This equivalence provides a simple method to estimate the ridge penalty parameter in comparison to other computationally-demanding estimation approaches based on cross-validation schemes. We evaluated the proposed test using simulation studies and applied it to real data from the Baependi Heart Study consisting of 76 families. Using our approach, we identified an interaction between BMI and the Peroxisome Proliferator Activated Receptor Gamma (PPARG) gene associated with diabetes. Full article

Remote-sensing-derived elevation data sets often suffer from noise and outliers due to various reasons, such as the physical limitations of sensors, multiple reflectance, occlusions and low contrast of texture. Outliers generally have a seriously negative effect on DEM construction. Some interpolation methods like ordinary kriging (OK) are capable of smoothing noise inherent in sample points, but are sensitive to outliers. In this paper, a robust algorithm of multiquadric method (MQ) based on an Improved Huber loss function (MQ-IH) has been developed to decrease the impact of outliers on DEM construction. Theoretically, the improved Huber loss function is null for outliers, quadratic for small errors, and linear for others. Simulated data sets drawn from a mathematical surface with different error distributions were employed to analyze the robustness of MQ-IH. Results indicate that MQ-IH obtains a good balance between efficiency and robustness. Namely, the performance of MQ-IH is comparative to those of the classical MQ and MQ based on the Classical Huber loss function (MQ-CH) when sample points follow a normal distribution, and the former outperforms the latter two when sample points are subject to outliers. For example, for the Cauchy error distribution with the location parameter of 0 and scale parameter of 1, the root mean square errors (RMSEs) of MQ-CH and the classical MQ are 0.3916 and 1.4591, respectively, whereas that of MQ-IH is 0.3698. The performance of MQ-IH is further evaluated by qualitative and quantitative analysis through a real-world example of DEM construction with the stereo-images-derived elevation points. Results demonstrate that compared with the classical interpolation methods, including natural neighbor (NN), OK and ANUDEM (a program that calculates regular grid digital elevation models (DEMs) with sensible shape and drainage structure from arbitrarily large topographic data sets), and two versions of MQ, including the classical MQ and MQ-CH, MQ-IH has a better ability of maximally reducing the impact of outliers, while faithfully preserving terrain features. Theoretically, MQ-IH is not a promising interpolation method, and some side effects can be found from its simulation results. For example, the contours of MQ-IH are coarser than ANUDEM in some locations of the real-world study site, and its hill shade may not strictly agree with the real-world surface at rough terrain. Furthermore, the computing cost of MQ-IH is much bigger than that of the classical interpolation methods. However, compared with the classical interpolation methods, MQ-IH has significant potential for interpolating remote-sensing-derived elevation data sets. Full article