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Search Results (2,511)

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20 pages, 612 KB  
Article
Humor That Hurts: An Exploration of Jokes About Black Women with Disabilities on TikTok in South Africa
by Fabiana Battisti and Lorenzo Dalvit
Journal. Media 2025, 6(4), 174; https://doi.org/10.3390/journalmedia6040174 - 8 Oct 2025
Abstract
Since the end of Apartheid in 1994, South Africa has striven to address past discrimination against members of marginalized groups such as Africans, women and LGBTQ+ individuals. Sophisticated media legislation and a vibrant civil society forged in the struggle against Apartheid ensure limited [...] Read more.
Since the end of Apartheid in 1994, South Africa has striven to address past discrimination against members of marginalized groups such as Africans, women and LGBTQ+ individuals. Sophisticated media legislation and a vibrant civil society forged in the struggle against Apartheid ensure limited discrimination in traditional media and relatively fringe online forums. However, subtle forms of undermining signal the persistent legacy of a colonial and patriarchal past. While incidents of online racism and sexism are relatively well documented, ableism deserves more attention. Despite growing scholarship on digital discrimination, a significant research gap remains in understanding how ableist microaggressions manifest online, particularly when intersecting with race and gender. As a result of established media tropes, microaggressions against people with disabilities are somewhat naturalized and reproduced on social media, yet their intersectional dimensions—especially targeting Black women with disabilities—remain underexplored. This paper addresses this gap through a focused case study of jokes targeting Black women with disabilities in one TikTok video and the approximately 700 comments. Considering (dis)ability’s intersections with race, gender, and socio-economic status, these media texts are subjected to a critical thematic analysis. The study also problematizes the methodological challenges associated with finding, identifying, and purposively selecting such content. The analysis reveals a set of historically and contextually rooted microaggressions expressed through humor, which, as a cultural expression, is inherently covert and thus hard to detect and regulate. This research contributes to understanding how intersectional ableism operates digitally and highlights the need for nuanced approaches to identifying subtle forms of discrimination in online spaces. Full article
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17 pages, 2767 KB  
Article
A Novel Whole-Body Wearable Technology for Motor Assessment in Multiple Sclerosis: Feasibility and Usability Pilot Study
by Jessica Podda, Erica Grange, Claudia Latella, Andrea Tacchino, Enrico Valli, Ludovica Danovaro, Gianluca Milani, Marco Forleo, Antonella Tatarelli, Davide Gorbani, Alex Coppola, Ludovico Pedullà, Giampaolo Brichetto and Daniele Pucci
Sensors 2025, 25(19), 6214; https://doi.org/10.3390/s25196214 - 7 Oct 2025
Abstract
(1) Background: Technological advancements provide new opportunities to objectively assess motor deficits in people with Multiple Sclerosis (PwMS). This pilot study aimed to evaluate the performance and usability of iFeel, a novel wearable system which integrates inertial sensors, instrumented shoes, and an AI-based [...] Read more.
(1) Background: Technological advancements provide new opportunities to objectively assess motor deficits in people with Multiple Sclerosis (PwMS). This pilot study aimed to evaluate the performance and usability of iFeel, a novel wearable system which integrates inertial sensors, instrumented shoes, and an AI-based algorithm. (2) Methods: Sixteen adult PwMS (Expanded Disability Status Scale—EDSS ≤ 6) performed motor tests (Timed 25-Foot Walk—T25FW; Timed Up and Go—TUG) both with and without the iFeel suit. Patient-reported outcomes (PROs) were also collected to assess perceived fatigue, dual-task impact, and walking difficulties. System Usability Scale (SUS) and ad hoc questionnaires have been further administered to test usability. (3) Results: No significant differences were found between the clinician and system-based scores for both T25FW (p = 0.383) and TUG (p = 0.447). Reliability analyses showed good agreement for T25FW (Intraclass Correlation Coefficient—ICC = 0.83) and excellent agreement for TUG (ICC = 0.92). Sensor-derived measures correlated strongly with PROs on fatigue, dual-task interference, and mobility. Usability was rated high (SUS: 78.6 ± 16.1), with participants reporting minimal discomfort and positive perceptions of iFeel usefulness for rehabilitation, health monitoring, and daily activities. (4) Conclusions: This pilot study provides preliminary yet promising evidence on the feasibility, usability, and perceived usefulness of the iFeel technology for motor assessment in PwMS. The findings support its further development and potential integration into clinical practice, particularly for remote or continuous motor monitoring. Full article
(This article belongs to the Special Issue Sensor-Based Rehabilitation in Neurological Diseases)
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48 pages, 3488 KB  
Systematic Review
From Static to Adaptive: A Systematic Review of Smart Materials and 3D/4D Printing in the Evolution of Assistive Devices
by Muhammad Aziz Sarwar, Nicola Stampone and Muhammad Usman
Actuators 2025, 14(10), 483; https://doi.org/10.3390/act14100483 - 3 Oct 2025
Viewed by 120
Abstract
People with disabilities often face challenges like moving around independently and depending on personal caregivers for daily life activities. Traditional assistive devices are universally accepted by these communities, but they are designed with one-size-fits-all approaches that cannot adjust to individual human sizes, are [...] Read more.
People with disabilities often face challenges like moving around independently and depending on personal caregivers for daily life activities. Traditional assistive devices are universally accepted by these communities, but they are designed with one-size-fits-all approaches that cannot adjust to individual human sizes, are not easily customized, and are made from rigid materials that do not adapt as a person’s condition changes over time. This systematic review examines the integration of smart materials, sensors, actuators, and 3D/4D printing technologies in advancing assistive devices, with a particular emphasis on mobility aids. In this work, the authors conducted a comparative analysis of traditional devices with commercially available innovative prototypes and research stage assistive devices by focusing on smart adaptable materials and sustainable additive manufacturing techniques. The results demonstrate how artificial intelligence drives smart assistive devices in hospital decentralized additive manufacturing, and policy frameworks agree with the Sustainable Development Goals, representing the future direction for adaptive assistive technology. Also, by combining 3D/4D printing and AI, it is possible to produce adaptive, affordable, and patient centered rehabilitation with feedback and can also provide predictive and preventive healthcare strategies. The successful commercialization of adaptive assistive devices relies on cost effective manufacturing techniques clinically aligned development supported by cross disciplinary collaboration to ensure scalable, sustainable, and universally accessible smart solutions. Ultimately, it paves the way for smart, sustainable, and clinically viable assistive devices that outperform conventional solutions and promote equitable access for all users. Full article
(This article belongs to the Section Actuators for Robotics)
15 pages, 615 KB  
Article
Exploring Emotional Intelligence, Attitudes Towards Disability, and Sexism Among Future Teachers in Spain
by Alberto Nolasco Hernández, Jesús Paz-Albo, Aránzazu Hervás-Escobar and Laura Gracia Sanchez
Educ. Sci. 2025, 15(10), 1291; https://doi.org/10.3390/educsci15101291 - 1 Oct 2025
Viewed by 234
Abstract
This research aimed to evaluate the emotional intelligence of future teachers and its relationship with attitudes towards people with disabilities, sexism, and bullying behaviors. Using a non-experimental design under a quantitative approach, 1004 future teaching subjects were selected by convenience sampling from different [...] Read more.
This research aimed to evaluate the emotional intelligence of future teachers and its relationship with attitudes towards people with disabilities, sexism, and bullying behaviors. Using a non-experimental design under a quantitative approach, 1004 future teaching subjects were selected by convenience sampling from different Faculties of Education in Spanish universities. The following instruments were applied online: for emotional intelligence, the TMMS-24; for bullying assessment, the Bullying Questionnaire-CAME; the General Scale of Attitudes towards People with Disabilities (2016) and the Ambivalent Sexism Inventory (ASI). Results indicated that both male and female future teachers exhibited low levels of emotional intelligence. A correlation was observed between greater emotional intelligence and more positive attitudes towards people with disabilities, as well as a lower tendency towards sexism. Additionally, a relationship was found between greater emotional attention and a lower tendency to bully from the victim’s perspective. These findings highlight the importance of developing emotional intelligence in future teachers to improve their interactions with students and promote a more inclusive and respectful school environment. Full article
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18 pages, 1181 KB  
Article
Inclusion in Higher Education: An Analysis of Teaching Materials for Deaf Students
by Maria Aparecida Lima, Ana Garcia-Valcárcel and Manuel Meirinhos
Educ. Sci. 2025, 15(10), 1290; https://doi.org/10.3390/educsci15101290 - 30 Sep 2025
Viewed by 412
Abstract
This study investigates the challenges of promoting accessibility for deaf teachers and students in higher education, focusing on the development of inclusive teaching materials. A qualitative case study was conducted in ten teacher training programmes at the Federal University of Alagoas (Brazil), including [...] Read more.
This study investigates the challenges of promoting accessibility for deaf teachers and students in higher education, focusing on the development of inclusive teaching materials. A qualitative case study was conducted in ten teacher training programmes at the Federal University of Alagoas (Brazil), including nine distance learning courses and one face-to-face LIBRAS programme. Analysis of the Virtual Learning Environment revealed a predominance of text-based content, with limited use of Libras videos, visual resources, or assistive technologies. The integration of Brazilian Sign Language into teaching practices was minimal, and digital translation tools were rarely used or contextually appropriate. Educators reported limited training, technical support, and institutional guidance for the creation of accessible materials. Time constraints and resource scarcity further hampered inclusive practices. The results highlight the urgent need for institutional policies, continuous teacher training, multidisciplinary support teams, and the strategic use of digital technologies and Artificial Intelligence (AI). Compared with previous studies, significant progress has been made. The present study highlights the establishment of an Accessibility Centre (NAC) and an Accessibility Laboratory (LAB) at the university. These facilities are designed to support the development of policies for the inclusion of people with disabilities, including deaf students, and to assist teachers in designing educational resources, which is essential for enhancing accessibility and learning outcomes. Artificial intelligence tools—such as sign language translators including Hand Talk, VLibras, SignSpeak, Glove-Based Systems, the LIBRAS Online Dictionary, and the Spreadthesign Dictionary—can serve as valuable resources in the teaching and learning process. Full article
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3 pages, 157 KB  
Editorial
Special Issue: Molecular Research on Mental Disorders 2.0
by Magdalena Sowa-Kućma
Int. J. Mol. Sci. 2025, 26(19), 9555; https://doi.org/10.3390/ijms26199555 - 30 Sep 2025
Viewed by 194
Abstract
Mental disorders remain one of the leading causes of disability worldwide, affecting more than 970 million people and contributing substantially to the global burden of disease [...] Full article
(This article belongs to the Special Issue Molecular Research on Mental Disorders 2.0)
24 pages, 1542 KB  
Article
Investigating Learning Assistance by Demonstration for Robotic Wheelchairs: A Simulation Approach
by Vinícius Barbosa Schettino, Murillo Ferreira dos Santos and Paolo Mercorelli
Robotics 2025, 14(10), 136; https://doi.org/10.3390/robotics14100136 - 28 Sep 2025
Viewed by 146
Abstract
A major challenge for robots that provide physical assistance is adapting to the needs of different people. To overcome this, personalised assistive models can be created by observing the demonstrations of help provided by an assistant, a setting known as Learning Assistance by [...] Read more.
A major challenge for robots that provide physical assistance is adapting to the needs of different people. To overcome this, personalised assistive models can be created by observing the demonstrations of help provided by an assistant, a setting known as Learning Assistance by Demonstration (LAD). In this work, the case of robotic wheelchairs and drivers with hand control disabilities, which make navigation more challenging, was considered. To better understand LAD and its features, a simulator capable of generating repeatable examples of the triadic interactions between drivers, robots, and assistants was developed. The software is designed to be modular and parametrisable, enabling customisation and experimentation with various synthetic disabilities and scenarios. This approach was employed to design more effective data collection procedures and to enhance learning models. With these, it is shown that, at least in simulation, LAD can be used as follows: for different disabilities; to help consistently; to generalise to physically different environments; and to create customised assistive policies. In summary, the results provide further evidence that LAD is a viable approach for efficiently creating personalised assistive solutions for robotic wheelchairs. Full article
(This article belongs to the Section Intelligent Robots and Mechatronics)
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24 pages, 6346 KB  
Article
Accessibility Challenges in the 15-Minute City Concept for People with Disabilities in Timișoara, România
by Ioana Antonia Tănase and Cristina Maria Povian
Sustainability 2025, 17(19), 8727; https://doi.org/10.3390/su17198727 - 28 Sep 2025
Viewed by 368
Abstract
Proximity-oriented planning aims to deliver everyday services within a short walk, yet closeness does not guarantee usable access for all residents. This study quantifies the gap between spatial proximity and functional accessibility in Timișoara, România, focusing on people with mobility and visual impairments. [...] Read more.
Proximity-oriented planning aims to deliver everyday services within a short walk, yet closeness does not guarantee usable access for all residents. This study quantifies the gap between spatial proximity and functional accessibility in Timișoara, România, focusing on people with mobility and visual impairments. A three-stage analysis was conducted to evaluate accessibility to public amenities. First, (1) a survey was conducted with 605 respondents to identify distinct accessibility priorities based on 15-Minute City core dimensions defined by Carlos Moreno and adapted afterwards to the city context and needs. In the second stage (2), GIS mapping (radial buffers and isochrones) revealed major disparities among non-disabled residents and residents with mobility and visual impairments. Coverage decreased substantially across amenities under reduced-speed scenarios and after excluding wheelchair-inaccessible destinations. In the third stage (3), field-observed pedestrian routes in three areas of Timișoara were examined against the top-ranked criteria for each group, using the items sourced from the previous survey and grounded in the 15-Minute City concept. The route scoring is exploratory and specific to this context. The findings confirmed recurrent functional barriers, especially for vulnerable groups. These results expose a proximity-accessibility gap, where apparent nearness masks physical or sensory barriers. A shift toward experience-based accessibility planning is needed to ensure that proximity is not only spatial, but also usable by all and inclusive. Full article
(This article belongs to the Section Environmental Sustainability and Applications)
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14 pages, 1188 KB  
Systematic Review
The Effects of Physical Exercise on Depression and Anxiety in Cancer Patients: A Systematic Review
by Giacomo Farì, Annatonia Fai, Francesco Quarta, Morena Pitruzzella, Cristiano Sconza, Matteo Luigi Giuseppe Leoni, Giustino Varrassi, Marco Filipponi, Giuseppe Rollo, Alessio Baricich and Andrea Bernetti
Clin. Pract. 2025, 15(10), 180; https://doi.org/10.3390/clinpract15100180 - 28 Sep 2025
Viewed by 452
Abstract
Background: Depression affects around 280 million people globally and is one of the main causes of disability. Among people with cancer, depression and anxiety affect 20–25%, significantly reducing quality of life, adherence to treatments, and survival. Despite the availability of pharmacological and [...] Read more.
Background: Depression affects around 280 million people globally and is one of the main causes of disability. Among people with cancer, depression and anxiety affect 20–25%, significantly reducing quality of life, adherence to treatments, and survival. Despite the availability of pharmacological and psychological treatments, their application can be limited by side effects, accessibility, and costs—especially in low- and middle-income countries. Physical exercise is emerging as a valuable complementary strategy, improving both physical and mental well-being. Nevertheless, structured exercise programs are still rarely implemented in oncology. This review aims to provide evidence-based recommendations for integrating physical activity into mental health support for people with cancer. Methods: This review includes six randomized controlled trials (RCTs) evaluating physical exercise interventions for depression and anxiety in people with cancer aged over 18 years. Included studies compared exercise interventions to control or standard care and reported outcomes related to psychological well-being and adverse effects. Exclusion criteria included non-original studies, non-English articles, and works not focused on exercise. The search was conducted in PubMed, Scopus, Google Scholar, and the Cochrane Library using MeSH terms and Boolean operators. The review protocol was registered in PROSPERO (CRD42025637522). Results: Exercise interventions—such as aerobic, resistance, and mind–body practices—proved effective and feasible across cancer types. Benefits were seen in both psychological and physical outcomes. However, variations in protocols and outcome measures, as well as a lack of long-term data, limit generalizability. Conclusions: Personalized exercise programs can significantly reduce depression and anxiety in people with cancer. Standardized core methods, long-term research, and systemic support are needed to integrate exercise into routine oncology care. Full article
(This article belongs to the Special Issue Exercise and Sports for Chronic Diseases)
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23 pages, 454 KB  
Review
A Literature Survey on the Additional Costs of Living for People with Disabilities
by Eleftheria Zervou and Marina-Selini Katsaiti
Soc. Sci. 2025, 14(10), 574; https://doi.org/10.3390/socsci14100574 - 25 Sep 2025
Viewed by 320
Abstract
The existing literature estimating the additional costs of living faced by people with disabilities is still scarce, despite its relatively long existence. At the moment, existing studies have focused mainly on EU, Anglo-Saxon countries, Malaysia, the Philippines, Ghana, Vietnam, Cambodia, one state in [...] Read more.
The existing literature estimating the additional costs of living faced by people with disabilities is still scarce, despite its relatively long existence. At the moment, existing studies have focused mainly on EU, Anglo-Saxon countries, Malaysia, the Philippines, Ghana, Vietnam, Cambodia, one state in India, sub-Saharan Africa, and China. This limited geographical coverage provides certain estimates for a large fraction of the OECD countries, along with non-representative samples from most other countries, leaving behind more than 75% of the countries worldwide. The main disadvantage of the scarcity of studies relates to the difficulty in estimation and the unavailability of data on disability and related costs. This study surveys the literature on the additional costs of living for people with disabilities. It summarizes the models of disability, the categorization of different costs, the cost assessment methods, and the reasons for difficulty in measuring/estimating costs. We present all studies in the literature received estimating the additional costs of living for people with disabilities, along with the methods used and the geographical areas investigated. The main conclusions drawn from the present survey point to significant additional costs of living for people with disabilities, depending on the type and intensity of disability, which in all cases are not less than 20% of household income, and increase significantly depending on the specifics. Full article
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16 pages, 973 KB  
Article
ConnectUp: Co-Designing an Online Social Connection Platform with People with Disabilities and Carers
by Dominika Kwasnicka, Sophie Jokovich, Chelsea Atherton, Emily Joy, Genevieve Mullen, Joanne McVeigh, Stuart Jenkinson, Jessica Hatton, Paul Rogers, Ashul Shah, Enrique Mergelsberg and Craig Thompson
Behav. Sci. 2025, 15(10), 1299; https://doi.org/10.3390/bs15101299 - 23 Sep 2025
Viewed by 190
Abstract
People with disabilities (PwD) and carers report higher levels of isolation and lower physical activity (PA) participation than the general population. Yet, both PA and social connection are linked to improved health and quality of life. Innovative approaches are needed to address these [...] Read more.
People with disabilities (PwD) and carers report higher levels of isolation and lower physical activity (PA) participation than the general population. Yet, both PA and social connection are linked to improved health and quality of life. Innovative approaches are needed to address these disparities. This study aimed to (1) explore PwD and carers’ experiences with PA, social connection, and online platforms, and (2) examine their preferences and expectations for online tools supporting these needs. Six workshops (N = 17; 6 PwD, 6 carers, 5 both; aged 20–73 years, M = 52.94, SD = 15.21) involved the co-design of the ConnectUp platform prototype. Data were analyzed using reflective thematic analysis, identifying four key themes: (1) safety and vulnerability online; (2) disability inclusion and creating authentic social connections; (3) physical activity and disability; and (4) meaningful representation of PwD and carers on online platforms. Participants emphasized the need for platforms that foster genuine inclusion, real connections, and support for PA. The co-design process ensured these preferences shaped platform development. The ConnectUp prototype is currently being further co-developed and refined for national rollout, aiming to reduce isolation and promote wellbeing for PwD and carers through inclusive digital engagement. Full article
(This article belongs to the Special Issue Psychology of Health Behavior Change)
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17 pages, 387 KB  
Review
Creative Arts Therapies, Psychomotor Therapy, and Play Therapy for People with Severe Intellectual Disabilities and Challenging Behaviour: A Scoping Review of Interventions and Outcomes
by Nikki H. T. Verdellen-Krauwel, Noud Frielink, Anna-Eva J. C. Prick, Arno P. A. M. Willems and Petri J. C. M. Embregts
Disabilities 2025, 5(4), 84; https://doi.org/10.3390/disabilities5040084 - 23 Sep 2025
Viewed by 549
Abstract
Individuals with severe intellectual disabilities and challenging behaviour often face limited access to effective therapeutic interventions, as conventional approaches like cognitive behavioural therapy may not be suitable. Creative arts therapies (CATs), psychomotor therapy, and play therapy have emerged as promising non-verbal alternatives, yet [...] Read more.
Individuals with severe intellectual disabilities and challenging behaviour often face limited access to effective therapeutic interventions, as conventional approaches like cognitive behavioural therapy may not be suitable. Creative arts therapies (CATs), psychomotor therapy, and play therapy have emerged as promising non-verbal alternatives, yet their use in this population remains underexplored. This scoping review aimed to map and synthesize the existing evidence on the application and outcomes of these interventions for individuals with severe intellectual disabilities and challenging behaviour. A comprehensive search was conducted across eight databases in May 2023 (with an update of the search in June 2025). Thirteen studies met the inclusion criteria, namely eight quantitative and five qualitative designs. Interventions included music therapy (n = 7), art therapy (n = 4), a combination of both (n = 1), and play therapy (n = 1); no studies on psychomotor therapy were identified. Reported outcomes were grouped into five domains: cognitive, psychological and emotional, social and interactional, communicative, and creative domain. Improvements were observed in areas such as attention, emotional regulation, social responsiveness, and communicative expression, particularly in structured and attuned therapeutic environments. However, most studies had methodological limitations, including small sample sizes and limited standardisation. These findings suggest potential benefits of CATs and play therapy, while highlighting the need for further research into underrepresented modalities and the use of rigorous single-case experimental designs. Full article
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18 pages, 417 KB  
Review
Enhancing Accessibility in Education Through Brain–Computer Interfaces: A Scoping Review on Inclusive Learning Approaches
by Mohammed Abdulmawjood and Kiemute Oyibo
Appl. Sci. 2025, 15(18), 10215; https://doi.org/10.3390/app151810215 - 19 Sep 2025
Viewed by 468
Abstract
Brain–computer interfaces (BCIs) hold promise in enhancing accessibility in education by enabling students with physical disabilities to interact with digital learning environments without barriers. However, no comprehensive review has explored the landscape and role of BCIs in inclusive learning. Hence, this review sets [...] Read more.
Brain–computer interfaces (BCIs) hold promise in enhancing accessibility in education by enabling students with physical disabilities to interact with digital learning environments without barriers. However, no comprehensive review has explored the landscape and role of BCIs in inclusive learning. Hence, this review sets out to identify relevant literature on BCI-based educational technologies, highlight their key themes, characteristics, and research methodologies, and identify research gaps. The secondary aim is to evaluate how these educational technologies contribute to inclusive learning frameworks by fostering communication, collaboration, engagement, and accessibility among students with disabilities. Overall, the reviewed studies demonstrate that BCIs can facilitate assistive communication among non-verbal students and provide motor control support for physically impaired persons. While these interventions show strong potential, challenges remain, including high implementation costs, user adaptability, and ethical concerns related to neural data privacy. Specifically, there is a need to (1) shift from experimental applications towards real-world classroom integration by developing user-friendly, cost-effective, and ethically sound BCI-based educational technologies, and (2) extend ongoing research efforts to include underserved populations to assess the generalizability of current and future BCI-based interventions. More importantly, future work should focus on enhancing BCI usability, improving adaptability for diverse learners, and establishing ethical guidelines for the development of socially responsible and inclusive neuro-educational technologies for all people with disabilities everywhere. This will go a long way in fostering the fourth and tenth United Nations Sustainable Development Goals of Quality Education and Reduced Inequalities, respectively. Full article
(This article belongs to the Special Issue Emerging Technologies in Innovative Human–Computer Interactions)
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16 pages, 458 KB  
Review
Guillain–Barré Syndrome in Older People—A Case Report and Literature Review
by Xiaomei Chen, Win Ko, Fiza Waseem, Lidia Cilcic, Nahian Kazi and Ahmed Abdelhafiz
Diseases 2025, 13(9), 306; https://doi.org/10.3390/diseases13090306 - 18 Sep 2025
Viewed by 633
Abstract
Guillain–Barré syndrome (GBS) is the most common acute inflammatory motor polyneuropathy. It affects all age groups, but the incidence increases with increasing age. Before manifesting with neurological symptoms, it is usually preceded by a prodromal phase of infection, most commonly respiratory or gastrointestinal. [...] Read more.
Guillain–Barré syndrome (GBS) is the most common acute inflammatory motor polyneuropathy. It affects all age groups, but the incidence increases with increasing age. Before manifesting with neurological symptoms, it is usually preceded by a prodromal phase of infection, most commonly respiratory or gastrointestinal. Pathologically, it is a post-infection immune disorder. The immune response is due to mimicry between the infecting agent and axolemmal surface molecules, which triggers an acute immune injury that leads to blockade of nerve conduction. Age-related decline in immune function plays a role in the increased prevalence and severity of GBS in older people. Typical neurological manifestations are ascending paralysis, areflexia and cranial nerve involvement, but sensory loss is uncommon. In up to 25% of cases, autonomic dysfunction occurs, which includes cardiovascular, sudomotor, gastrointestinal or genitourinary symptoms. The development of autonomic dysfunction in GBS is associated with poor prognosis. We report a case of a 78-year-old man who presented with a predominant autonomic dysfunction that led to a delay in the diagnosis. Because of the multiple morbidities associated with old age, the diagnosis of GBS presentation with autonomic dysfunction, without the typical neurological clinical pattern, may be attributed to the existing comorbidities. Therefore, clinical suspicion and close monitoring with respect to the development of autonomic dysfunction, from the first day of hospital admission, are important. The main diagnostic tests are cerebrospinal fluid analysis looking for protein–cell dissociation and nerve conduction studies to confirm the neuropathy. Treatment involves general supportive care, specific immunological intervention by intravenous immunoglobulins or plasma exchange courses and neurorehabilitation. Severe cases may require intensive care admission and mechanical ventilation. More than 80% of cases will fully recover, but 10% may have residual disability, with mortality estimated at 3–7%. Older age, multiple morbidities, severe weakness, autonomic dysfunction and the need for mechanical ventilation are poor prognostic factors. Full article
(This article belongs to the Special Issue Research Progress in Neurodegenerative Diseases)
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14 pages, 480 KB  
Review
Sex and Relationship Education for Individuals with Disabilities: A Review of the Literature Through an Ecological Systems Lens
by Gustav Oppermann, Caroline Van Zant, Isabel Coughlan, Sophie Howarth, Nicole Sparapani and Kathryn Pedgrift
Sexes 2025, 6(3), 52; https://doi.org/10.3390/sexes6030052 - 17 Sep 2025
Viewed by 440
Abstract
Despite advances toward disability inclusion, high-quality sex and relationship education (SRE) is often inaccessible for disabled communities. Confounding this issue, each individual’s experience of SRE is shaped by aspects within their environment, such as societal contexts, cultural factors, policy frameworks at the national [...] Read more.
Despite advances toward disability inclusion, high-quality sex and relationship education (SRE) is often inaccessible for disabled communities. Confounding this issue, each individual’s experience of SRE is shaped by aspects within their environment, such as societal contexts, cultural factors, policy frameworks at the national and local levels, and the attitudes of parents and educators. This informal review of the literature synthesizes historical and contemporary literature—focusing primarily on individuals with intellectual disabilities and autism—to explore the multifaceted barriers and opportunities for effective SRE. We have situated the literature within Bronfenbrenner’s ecological systems theory to illuminate how interactions among and within the environment shape individual experiences with SRE. The literature outlines several barriers to successful SRE programs for the disabled community, including pervasive misconceptions about the sexual and relational needs of disabled individuals, inadequate training for educators, and limited empirical evidence underpinning best practices. Our paper underscores the need for comprehensive, evidence-based curricula that align with the desires of the disabled community, are accessible to people with disabilities and their communities, and employ a variety of instructional methods to support learning across the life course, beginning in adolescence. We conclude by outlining future directions for research and practical solutions for curriculum development, emphasizing the importance of addressing these multi-layered challenges to enhance SRE for disabled people and their communities. Approaching and conceptualizing the literature within a systems framework and through our shared perspectives and experiences is noteworthy, as our review provides a descriptive and unique lens to understanding SRE influences on people with disabilities nationally and internationally. Full article
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