Search Results (195)

Background/Objectives: Education on antibiotic use has the potential to positively shape the practices and perspectives of future professionals. Assessing awareness levels of antibiotic resistance among university students is, therefore, critical, as they represent a vital demographic capable of influencing public health outcomes, especially in low- and middle-income countries. Methods: This cross-sectional study employed the World Health Organization’s Antibiotic Resistance: Multi-Country Public Awareness Survey, which examines demographics, antibiotic use, knowledge, perspectives, and sources of information. A total of 922 surveys were collected from students across various disciplines at two universities in Greater Guayaquil. Results: Most participants reported obtaining antibiotics through healthcare professionals, adhering to proper usage instructions, and purchasing them primarily from pharmacies. However, only 56% of the responses were correct, with many students incorrectly associating antibiotic use with conditions where they are typically ineffective. Despite these gaps, the students expressed positive attitudes toward proposed measures to address antibiotic resistance. While the participants demonstrated familiarity with terms related to antibiotic resistance and identified doctors and educators as their main sources of information, educational campaigns were not widely recognized as important. Conclusions: These findings evidence knowledge gaps among an essential group, suggesting the need for targeted health programs, preventive strategies, and educational initiatives to combat misinformation regarding antimicrobial resistance. Full article

TikTok is a popular social media platform offering educational opportunities for health issues such as rheumatic fever, which primarily affects 4–19-year-olds globally. This content analysis aimed to explore the type of rheumatic fever content available and popular on TikTok and the role that rheumatic fever representation may play in shaping public understanding and attitudes. The top 100 TikTok video posts under the hashtag #rheumaticfever were examined. Descriptive statistics were used to summarize video metrics and deductive thematic analysis enabled the coding of video content. The majority of TikTok users creating rheumatic fever content were patients or family members of people suffering from rheumatic fever (42%), followed by health professionals (30%). Forty-three percent of videos had negative connotations and personal stories were the most commonly coded type of video (42%). In terms of rheumatic fever content, symptoms (n = 59), medications/treatment (n = 37) and disease pathogenesis (n = 36) were the most common themes. Misinformation was identified in 3% of videos. This study provides a unique insight into who is making rheumatic fever-related content on TikTok and the primarily negative framing of narratives people are exposed to. There are opportunities for future health promotion strategies to focus on the gaps identified in this study, including information on where to seek health services, primordial prevention and stories of recovery. Full article

Background: Resistance to vaccinations continues to pose a considerable challenge to attaining widespread vaccination, especially among the college student demographic, who are pivotal in championing public health initiatives. This systematic review investigates the elements that influence reluctance to receive the COVID-19 vaccine among university students globally. Utilizing the WHO’s 3C model, which encompasses confidence, complacency, and convenience, this review seeks to pinpoint the main factors and suggest focused strategies to address them. Methods: Following the PRISMA guidelines, we conducted a systematic search in PubMed, Medline, Web of Science, Scopus, Embase, and Global Health. Eligible studies were cross-sectional, peer-reviewed, and examined COVID-19 vaccine hesitancy among college students. Covidence was used for screening, and data were synthesized narratively using the 3C model. Results: Sixty-seven studies (n = 88,345 participants) from 25 countries were included in this study. Confidence factors were the most influential, with fear of side effects (87.18%) and doubts about efficacy (72.4%) as primary concerns. Complacency factors included a low perceived risk of infection (34.9%) and a preference for alternative preventive measures (52.3%). Convenience barriers involved financial costs (58.1%) and difficulty accessing vaccination centers (40.3%). Subgroup analyses revealed variations by academic discipline and geographic region, with medical students showing hesitancy despite their health knowledge. Conclusions: COVID-19 vaccine hesitancy among college students is primarily driven by safety concerns, misinformation, and accessibility barriers. Addressing hesitancy requires transparent risk communication, policy-driven accessibility improvements, and tailored educational interventions. These findings can inform strategies to enhance vaccine uptake among young adults and contribute to broader efforts in pandemic preparedness. Full article

The COVID-19 pandemic intensified concerns about misinformation, sparking interest in the field of infodemiology, which examines the spread and impact of information on public health perceptions. This research examines how geographic location influenced COVID-19 discourse across 10 Italian cities by analyzing geographically tagged Twitter data. Our network analysis of 4792 high-degree nodes identifies key information spreaders and community structures, while spatiotemporal mapping reveals regional variations in information patterns and influential narratives. Results demonstrate significant geographic and cultural influences on public discourse. In Milan and Rome, economic and political narratives dominated, suggesting targeted messaging about economic recovery and government transparency. Southern regions like Naples require trust-building through community-led initiatives addressing cultural health beliefs. The study identified a clear dichotomy among influencers: established public figures provided evidence-based information, while another group cultivated followings through conspiracy theories, creating echo chambers for skeptical views. This research informs strategies for location-specific information campaigns, helping public health agencies combat misinformation more effectively. Findings emphasize the need for context-specific interventions that consider geographic, cultural, and socioeconomic factors to enhance community resilience during health emergencies. Full article

Maternal immunization is a key strategy for protecting pregnant individuals and newborns from infectious diseases. This review examines the mechanisms and benefits of maternal immunization, with a focus on transplacental IgG transfer and immune system interactions. We provide an overview of current recommendations and the safety and efficacy profiles of maternal vaccines, including influenza, tetanus–diphtheria–acellular pertussis (Tdap), respiratory syncytial virus (RSV), COVID-19, and hepatitis B. Additionally, we analyze the barriers to maternal immunization, such as misinformation, vaccine hesitancy, and disparities in healthcare access, while exploring potential strategies to overcome these challenges through targeted educational initiatives, improved provider communication, and policy-driven interventions aimed at increasing vaccine confidence and accessibility. Finally, this review highlights recent innovations and future directions in maternal immunization, including emerging vaccines for Group B Streptococcus and cytomegalovirus. Expanding immunization programs and advancing research on maternal–fetal immunity are essential to optimizing vaccination strategies, improving public health outcomes, and reducing the global burden of infectious diseases. Full article

Cervical cancer (CC) is the only cancer that has the possibility of primary and secondary prevention. Despite this, it is one of the leading causes of cancer death among women, especially in developing countries. The World Health Organization has set the ambitious goal of eliminating CC by 2030 by suggesting specific types of intervention. Unfortunately, to date, we are very far from this goal at a global level, including developed countries. Implementing vaccination coverage among the target population is one of the strategies to be pursued in this area. Achieving this goal should include combating misinformation about the HPV vaccine, which is one of the main reasons for vaccination hesitancy. Such conspiracy theories are prevalent on social media, one of the primary sources of information for adults and adolescents today. In this regard, the Internet plays a significant role in disseminating information about the HPV vaccine, both positively and negatively. The Internet provides easy access to information about the HPV vaccine, including its safety, efficacy, recommended dosing schedule, and potential side effects. It may promote vaccine advocacy and debunking vaccine myths. On the other hand, the Internet may be the place for disseminating misinformation and influencing vaccine decision making. It is a double-edged sword in shaping public discourse and perceptions about the HPV vaccine. This overview aims to assess the literature on this topic in depth to promote evidence-based information, analyze the social channels through which misinformation spreads, and leverage digital health interventions essential for promoting HPV vaccination and reducing the burden of HPV-related diseases. Full article

During the COVID-19 pandemic, vaccination hesitancy (VH) posed an equally unexpected and significant obstacle to the effectiveness of public health interventions. VH has not only the potential to stir up public unrest, but it may also impede the success of entire immunization programs and thus prevent the attainment of herd immunity. This cross-sectional, quantitative, and descriptive study examined VH and vaccination behavior (VB) among 3486 university students in Ghana, using a standardized self-administered questionnaire based on the 5Cs model among other relevant variables. The findings confirm a significant VH and a VB influenced by both sociodemographic factors, such as gender (OR: 1.45; [CI: 1.26–1.67]), study program (OR: 0.55; [CI: 0.47–0.64]), and ethnicity (OR: 1.31; [CI: 1.12–1.52]) and also four of the 5Cs, i.e., Confidence (OR:1.56; [CI: 1.45–1.68]), Constraints (OR: 0.83; [CI: 0.78–0.87]), Calculation (OR:0.85; [CI: 0.78–0.92]), and Collective Responsibility (OR:1.27; [CI: 1.16–1.38]), yet not Complacency, nor religion. Notably, VH was further shaped by previous vaccine experience, information sources, vaccine attributes, stance on vaccine passport, and conspiracy beliefs, with misinformation from unofficial sources playing a key role. The multiple regression models explained 11% to 34% of the variance in the 5Cs, indicating varying degrees of explanatory power for each factor influencing VB and eventually also VH. This study highlights the urgent need for targeted public health interventions, such as integrating vaccine education into university orientation programs, streamlining vaccination processes, and leveraging influencers for trust-building campaigns. Full article

Background: The COVID-19 pandemic highlighted the vulnerability of immunocompromised individuals, including liver transplant recipients (LTRs), who often exhibit reduced vaccine immunogenicity. While initial vaccine doses and subsequent boosters improved immune response, LTRs were prioritized for vaccination. Studies have shown increased antibody response after each booster dose. Vaccine hesitancy, defined as delayed or refused vaccination despite availability, poses a public health challenge, often fueled by misinformation. This study aimed to evaluate anti-spike antibody responses in vaccinated LTRs after two initial doses and at least one booster, also assessing adherence to subsequent doses. Methods: We conducted a retrospective observational study at a transplant center in Milan, Italy, between January 2021 and December 2023. LTRs who had received four or more doses of mRNA vaccines (Pfizer or Moderna) were included. Anti-spike antibody levels were measured 60–80 days after each dose. Data on vaccination status were collected in January 2024. Statistical analysis was performed to compare antibody responses and identify predictive factors. Results: LTRs showed a significant increase in anti-spike antibody responses after the first booster compared to the second dose with a trend versus a further increase following the fourth dose in a subgroup of the patients receiving two booster doses. However, adherence to booster doses decreased over time. In LTRs, predictors of a weaker response after the second dose were chronic kidney disease and metabolic etiology at transplant. Conclusions: The study highlighted that in LTRs, multiple doses of the COVID-19 vaccine led to a continuous increase in anti-spike antibody responses. The progressive decline in adherence of LTRs “to further booster doses” should be related to the fact that after the spread of vaccination programs worldwide, COVID-19 is still a current infection, but it is much less severe than before. Full article

The rapid emergence of infectious disease outbreaks has underscored the urgent need for effective communication tools to manage public health crises. Artificial Intelligence (AI)-based chatbots have become increasingly important in these situations, serving as critical resources to provide immediate and reliable information. This review examines the role of AI-based chatbots in public health emergencies, particularly during infectious disease outbreaks. By providing real-time responses to public inquiries, these chatbots help disseminate accurate information, correct misinformation, and reduce public anxiety. Furthermore, AI chatbots play a vital role in supporting healthcare systems by triaging inquiries, offering guidance on symptoms and preventive measures, and directing users to appropriate health services. This not only enhances public access to critical information but also helps alleviate the workload of healthcare professionals, allowing them to focus on more complex tasks. However, the implementation of AI-based chatbots is not without challenges. Issues such as the accuracy of information, user trust, and ethical considerations regarding data privacy are critical factors that need to be addressed to optimize their effectiveness. Additionally, the adaptability of these chatbots to rapidly evolving health scenarios is essential for their sustained relevance. Despite these challenges, the potential of AI-driven chatbots to transform public health communication during emergencies is significant. This review highlights the importance of continuous development and the integration of AI chatbots into public health strategies to enhance preparedness and response efforts during infectious disease outbreaks. Their role in providing accessible, accurate, and timely information makes them indispensable tools in modern public health emergency management. Full article

Vaccinations are among the most effective means of preventing hospitalizations related to infections. Despite this, high hospitalization rates for vaccine-preventable diseases strain available healthcare resources and imply deficiencies in primary care. Barriers to vaccinations exist, such as the recent pandemic, vaccine hesitancy, misinformation, and access to care. This study analyzes hospitalization rates due to vaccine-preventable conditions and identifies factors contributing to an increase in these rates in the southeast United States. This study used data from four different data sources. The data covers four pre-pandemic years (2016 to 2019) and the pandemic period (2020 to 2022). The analysis categorized the numbers and rates of hospitalizations for conditions with an available preventative vaccine across three age groups: pre-school aged children, school-aged children, and adults. Comparisons between school- versus non-school-mandated vaccines and a focus on differences between rural versus urban communities, as well as demographic characteristics (i.e., gender, race, and ethnicity), are included. Chi-squared tests were used to assess differences in this descriptive part of the analysis. Linear multiple regression was used to examine the independent influence of geographic location while accounting for potential longitudinal trends and the dimensions of the SVI, including socioeconomic status, household composition, disability, minority status and language, and household type and transportation. The dataset included data from 22,797,826 inpatient episodes, including 32,358 for which the principal reason for hospitalization was a vaccine-preventable condition, not including COVID-19. The analysis shows a consistent pattern characterized by higher rates of hospitalization for counties classified as rural. The pattern holds for preschool age (p < 0.001), school age (p = 0.004), and adults (p = 0.009). The differences are statistically significant in the white population (p = 0.008); in pre-school children, school-age children, and adults (p < 0.001); in females (p = 0.08 in pre-school, and p = 0.013 in adults); and black adults (p = 0.02). The regression results confirmed the findings of the descriptive analysis, indicating significantly higher rates in rural communities. Finally, the regression analysis also showed significantly higher rates associated with greater social vulnerability. This study highlights gaps in vaccination opportunities. These gaps can be seen geographically and in terms of social vulnerability, affected by factors such as poverty, language barriers, household composition, and access to care. Hospitalizations due to immunizable diseases were found to be higher in rural areas, particularly among adults. Communities with a high SVI show a significant increase in hospitalization rates. Community-engaged vaccination outreach programs and state policies could improve vaccination rates, and therefore, public health in rural areas, reducing hospitalizations, and lowering infectious disease risks in these areas. Full article

(1) Introduction: Human papillomavirus (HPV) is a significant public health concern associated with various cancers, including a rising incidence of oropharyngeal cancer (OPC). Despite the availability of effective vaccines targeting high-risk HPV types, vaccination rates remain suboptimal. Dental professionals are uniquely positioned to contribute to HPV prevention through education, vaccination advocacy, and early detection. (2) Methods: This narrative review synthesized the literature from 2006 to 2024 on HPV epidemiology, pathophysiology, vaccine efficacy, and the role of dental providers in HPV prevention. Sources included peer-reviewed articles listed in Pubmed and Google Scholar, including observational studies and review articles, guidelines, clinical trials, and governmental data. Key barriers to HPV-related care in dental practice and strategies for overcoming them were analyzed. (3) Results: The review underscores the critical role of dentists in HPV-related disease prevention, highlighting their ability to detect HPV-related lesions, promote vaccine uptake, and address patient concerns. Barriers such as limited knowledge, discomfort discussing HPV, and misinformation were identified. Strategies like incorporating HPV education into dental training, utilizing emerging diagnostic tools, and adopting effective communication approaches can enhance the role of dental professionals in reducing HPV-associated cancer risks. (4) Conclusion: By integrating HPV education, vaccination advocacy, and early detection into routine dental care, dental professionals can play a transformative role in public health. A dental provider’s endorsement can increase HPV vaccine uptake and help prevent oral cancer. These efforts align with broader health promotion goals, offering a significant opportunity to reduce the burden of HPV-associated cancers and improve long-term patient outcomes. Full article

Prolonged exposure to public health crises in the post-pandemic era poses significant threats to global mental health. To address this, we developed a conceptual model to analyse the spatiotemporal distribution of public emotions, using Weibo data from the 2022 Beijing bar outbreak (9 June–18 August). The model integrates lexicon-based emotion analysis, spatial autocorrelation tests, and content analysis to provide a comprehensive understanding of emotional responses across stages and regions. The findings reveal a multi-peak emotional cycle spanning emergency, contagion, and resolution stages, with significant emotional clustering in emergency zones, surrounding areas, and regions visited by infected individuals. Through coding, we identified 24 main-categories and 90 sub-categories, distilled into nine core themes that illustrate the interplay between influencing factors, public emotions, and online behaviours. Positive public emotions (e.g., hopefulness, gratitude, optimism) were linked to pandemic improvements and policy implementation, driving behaviours such as supporting prevention measures and resisting misinformation. Negative emotions (e.g., anger, anxiety, sadness) stemmed from severe outbreaks, insufficient controls, and restrictions on freedoms, leading to criticism and calls for accountability. This study bridges big data analytics with behavioural science, offering critical insights into evolving public emotions and behaviours. By highlighting spatiotemporal patterns and emotional dynamics, it provides actionable guidance for governments and health organizations to design targeted interventions, foster resilience, and better manage future social crises with precision and empathy. Full article

On 11 March 2020, the World Health Organization (WHO) declared a pandemic caused by SARS-CoV-2, raising global health concerns. Reports of persistent and new symptoms following the acute phase of infection highlighted the complexities of recovery and prompted the investigation of what is now termed long COVID. Officially recognized by the WHO in October 2021, long COVID presents various health implications, though the terminology—such as post-COVID syndrome and post-acute sequelae of COVID-19 (PASC)—remains inconsistent, complicating diagnostic standardization. Long COVID affects an estimated 10% to 30% of SARS-CoV-2-infected individuals, with common symptoms including fatigue, dyspnea, cognitive dysfunction, and joint pain, all of which significantly impair quality of life. Public perception is influenced by factors like education and health history, while misinformation and stigma hinder accurate diagnosis and treatment. The absence of biomarkers and overlap with other post-viral syndromes further complicate clinical recognition. Experts emphasize the need for refined diagnostic criteria and integrated strategies combining biomedical research, public policy, and educational initiatives to improve clinical management, address healthcare inequalities, and mitigate the impacts of long COVID. This review unveils the state of the art and knowledge gaps to encourage discussion, with the aim of achieving better clinical decision-making and public awareness related to long COVID. Full article

Background and Objectives: Schizophrenia is a significant public health issue, and YouTube has become an increasingly popular source of health information. This study aims to assess the quality and validity of YouTube videos about schizophrenia, focusing on the presence of scientific evidence and the role of healthcare professionals in content quality. Methods: A retrospective, cross-sectional observational study was conducted. One hundred videos in Spanish were selected using NodeXL Pro software, based on specific keywords and hashtags. The videos were categorized by content type and assessed using the DISCERN and Global Quality Scale [GQS] tools to evaluate quality and reliability. Results: Only 39% of the videos referenced scientific articles or technical documents. The videos created by healthcare professionals exhibited a higher quality and reliability. Significant differences were found in the DISCERN and GQS scores between the videos presenting personal opinions and those providing scientific information, favoring the latter. Conclusion: There is a prevalence of misinformation about schizophrenia on YouTube. To enhance the educational value of the platform and reduce misinformation risks, involving healthcare professionals in content creation and implementing control mechanisms is essential. Full article

Background/Objectives: The influence of media on the public opinion, especially regarding health topics, is profound. This study investigates how Spanish media may reinforce a positive image of dietary supplements for children, potentially leading to harmful health attitudes and behaviors. Methods: The researchers conducted a quantitative content analysis of 912 news articles from Spanish media outlets discussing dietary supplements for children between 2015 and 2021. They used a frequency analysis and a proportion comparison to analyze variables such as the reach of news, tone of news, mentions of health professional consultation, association with natural products, media specialization, intertextuality, and headline mentions. Results: The study found a 60% increase in publications discussing dietary supplements for children during the study period. The content analysis indicates that these articles predominantly present dietary supplements in a positive light, often without robust scientific evidence. Furthermore, many do not emphasize the need for medical consultation, which may contribute to unsupervised consumption, particularly among minors. This highlights the critical importance of professional guidance when considering dietary supplements for children. Additionally, the frequent emphasis on the “natural” attributes of these products raises concerns regarding consumer perceptions and potential safety risks. Conclusions: The study reveals a problem regarding the portrayal of dietary supplements for children in Spanish media. The overly optimistic image, lack of scientific basis, and failure to recommend medical supervision may contribute to unsupervised consumption among minors, risking their health due to misinformed decisions influenced by media portrayal. Full article