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Keywords = scaphoid fractures

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12 pages, 1399 KB  
Article
Surgical Treatment of Scaphoid Non-Union in Adolescents: A Modified Vascularized Bone Graft Technique
by Diletta Bandinelli, Alessia Pagnotta, Alessandro Piperno, Martina Marsiolo, Angelo Gabriele Aulisa and Francesco Falciglia
Children 2025, 12(9), 1135; https://doi.org/10.3390/children12091135 - 27 Aug 2025
Viewed by 856
Abstract
Background: Although adolescents are at a lower risk of developing scaphoid non-union than adults, this complication is not uncommon in younger patients. The current gold standard for surgical treatment is non-vascularized bone grafting from the iliac crest or distal radius, and it [...] Read more.
Background: Although adolescents are at a lower risk of developing scaphoid non-union than adults, this complication is not uncommon in younger patients. The current gold standard for surgical treatment is non-vascularized bone grafting from the iliac crest or distal radius, and it is often considered the first-line option. However, non-union can persist in 10–20% of cases, and failure rates can reach up to 50% when the proximal pole is necrotic. Methods: We evaluated a modified vascularized bone graft surgical technique in selected adolescent patients, with the goal of avoiding growth-related complications. Our experience is based on three cases of scaphoid non-union treated surgically between June 2019 and June 2022. Results and Conclusions: The modified surgical technique has shown promising results in the selected cases and carries no risk of donor site morbidity. It enables preservation of severely compromised scaphoid bones, prevents early-onset wrist osteoarthritis, and facilitates the return to sports activities for young patients. Full article
(This article belongs to the Special Issue Pediatric Upper Extremity Pathology)
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13 pages, 1490 KB  
Systematic Review
Prevalence of the Os Supranaviculare: A Systematic Review with Meta-Analysis
by Maksymilian Osiowski, Aleksander Osiowski, Maciej Preinl, Grzegorz Fibiger, Katarzyna Majka, Barbara Jasiewicz and Dominik Taterra
J. Clin. Med. 2025, 14(17), 5934; https://doi.org/10.3390/jcm14175934 - 22 Aug 2025
Viewed by 558
Abstract
Background/Objectives: The os supranaviculare (OSSN), also known as os talonaviculare dorsale, astragalo-scaphoid ossicle, or Pirie’s bone, is a small extra bone that was first described in 1921 by A.H. Pirie and is located at the top front part of the navicular bone [...] Read more.
Background/Objectives: The os supranaviculare (OSSN), also known as os talonaviculare dorsale, astragalo-scaphoid ossicle, or Pirie’s bone, is a small extra bone that was first described in 1921 by A.H. Pirie and is located at the top front part of the navicular bone or talonavicular joint. The knowledge regarding the epidemiology of the OSSN is scarcely established, as its prevalence remains unknown and varies significantly among multiple studies. This meta-analysis aims to clarify and systematically summarize all available data on the characteristics and prevalence of the OSSN. Methods: Four major databases (PubMed/Medline, Embase, ScienceDirect, Scopus) were thoroughly searched for studies reporting original data regarding the OSSN up until May 2025. The protocol of this study was pre-registered on PROSPERO (ID: CRD42025638111) and adhered to PRISMA guidelines. To evaluate the between-study heterogeneity, the 95% prediction intervals (95%PI) were calculated; I2 statistic and Chi2 test were also used. The AQUA-tool was used to assess the quality of included studies. Results: In total, 13 studies (18,745 feet) qualified for inclusion in the quantitative analysis. The pooled prevalence estimate (PPE) of the OSSN in the general population was found to be 0.88% (95%CI: 0.62–1.24%). The PPE of the OSSN was higher in males (0.87%, 95%CI: 0.58–1.32%) than in females (0.48%, 95%CI: 0.14–1.64%). The os supranaviculare was similarly prevalent in both European (1.04%, 95%CI: 0.55–1.96%) and Asian (0.87%, 95%CI: 0.66–1.13%) populations. Conclusions: the os supranaviculare is a very rare anatomical variation that is present in less than one in a hundred feet. Moreover, although usually asymptomatic, it can occasionally be associated with dorsal foot pain or navicular stress fractures. Accurate differentiation from avulsion fractures is essential to avoid unnecessary invasive treatment. Full article
(This article belongs to the Special Issue Foot and Ankle Surgery: Current Advances and Prospects)
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15 pages, 2537 KB  
Article
Comparative Assessment of the Mechanical Response to Different Screw Dimensions in Scaphoid Fracture Fixation
by Esin Rothenfluh, Sambhav Jain, William R. Taylor and Seyyed Hamed Hosseini Nasab
Bioengineering 2025, 12(8), 790; https://doi.org/10.3390/bioengineering12080790 - 22 Jul 2025
Viewed by 610
Abstract
The scaphoid is the most commonly fractured carpal bone. Headless compression screws became the gold standard for fixation, but the ideal screw diameter remains debated. This study investigates the relative benefit of using a larger screw diameter to improve stability in typical scaphoid [...] Read more.
The scaphoid is the most commonly fractured carpal bone. Headless compression screws became the gold standard for fixation, but the ideal screw diameter remains debated. This study investigates the relative benefit of using a larger screw diameter to improve stability in typical scaphoid fractures. It also examines the effects of preload and screw length on mechanical behaviour. A finite element (FE) model of a mid-waist scaphoid fracture was created. Screws from Medartis (1.7 mm, 2.2 mm, and 3.0 mm diameter; 23 mm length) were placed along the longitudinal axis. Boundary and loading conditions matched prior studies. Interfragmentary displacement (IFD) and von Mises stress were compared across screw sizes. The effects of screw length and preload were also evaluated. Maximum in-plane IFD was 2.08 mm (1.7 mm screw), 0.53 mm (2.2 mm), and 0.27 mm (3.0 mm). The 1.7 mm screw exceeded the scaphoid’s average ultimate stress (60.51 MPa). Increasing preload reduced IFD, especially above 60 N. Screws longer than 1.5 times the mid-waist diameter offered no added benefit. Larger screws provide better biomechanical fracture stability. However, the gain from 2.2 mm to 3.0 mm is minor, while 1.7 mm screws lack sufficient strength. The 2.2 mm screw offers a good balance of stability and bone preservation, making it the preferred choice. Full article
(This article belongs to the Special Issue Advanced Engineering Technologies in Orthopaedic Research)
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10 pages, 984 KB  
Article
Three-Dimensional-Planned Patient-Specific Guides for Scaphoid Reconstruction: A Comparative Study of Primary and Revision Nonunion Cases
by Michael A. Wirth, Mauro Maniglio, Benedikt C. Jochum, Sylvano Mania, Ladislav Nagy, Andreas Schweizer and Lisa Reissner
J. Clin. Med. 2025, 14(6), 2082; https://doi.org/10.3390/jcm14062082 - 19 Mar 2025
Viewed by 679
Abstract
Background: Scaphoid reconstruction after an established non- or malunion is challenging and recent developments have shown the feasibility to reconstruct it with 3D-planned and -printed patient-specific instrumentation. Methods: Our study compared the clinical outcome of computer assisted 3D-reconstructions of the scaphoid using patient-specific [...] Read more.
Background: Scaphoid reconstruction after an established non- or malunion is challenging and recent developments have shown the feasibility to reconstruct it with 3D-planned and -printed patient-specific instrumentation. Methods: Our study compared the clinical outcome of computer assisted 3D-reconstructions of the scaphoid using patient-specific guides for primary and revision reconstructions of scaphoid nonunion regarding clinical outcome. Therefore, 39 patients with primary scaphoid nonunion or malunion and 15 patients with nonunion or malunion after a previous operative treatment were treated with patient-specific guides and followed up for a mean of 10.5 months. The consolidation was assessed with a CT-scan, and the time to consolidation was recorded. Pain level, satisfaction, wrist range of motion, and grip strength were measured and compared. Results: The wrist range of motion and grip strength of the two groups were similar, except for the wrist extension, which was significantly reduced in the revision group. Consolidation was observed in 36/39 patients (92%) in the primary group and in 13/15 patients (87%) in the revision group. Our results showed similar clinical results postoperatively between primary reconstructions and revision surgery. Conclusions: The use of 3D-planned and -printed patient-specific instrumentation proves to be similarly effective in revision surgeries for the reconstruction of the scaphoid as it is in primary surgeries. Full article
(This article belongs to the Special Issue State of the Art in Hand Surgery)
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11 pages, 2567 KB  
Article
Deep Learning in Scaphoid Nonunion Treatment
by Leyla Tümen, Fabian Medved, Katarzyna Rachunek-Medved, Yeaeun Han and Dominik Saul
J. Clin. Med. 2025, 14(6), 1850; https://doi.org/10.3390/jcm14061850 - 9 Mar 2025
Viewed by 2543
Abstract
Background/Objectives: Scaphoid fractures are notorious for a high rate of nonunion, resulting in chronic pain and impaired wrist function. The decision for surgical intervention often involves extensive imaging and prolonged conservative management, leading to delays in definitive treatment. The effectiveness of such [...] Read more.
Background/Objectives: Scaphoid fractures are notorious for a high rate of nonunion, resulting in chronic pain and impaired wrist function. The decision for surgical intervention often involves extensive imaging and prolonged conservative management, leading to delays in definitive treatment. The effectiveness of such treatment remains a subject of ongoing clinical debate, with no universally accepted predictive tool for surgical success. The objective of this study was to train a deep learning algorithm to reliably identify cases of nonunion with a high probability of subsequent union following operative revision. Methods: This study utilized a comprehensive database of 346 patients diagnosed with scaphoid nonunions, with preoperative and postoperative X-rays available for analysis. A classical logistic regression for clinical parameters was used, as well as a TensorFlow deep learning algorithm on X-rays. The latter was developed and applied to these imaging datasets to predict the likelihood of surgical success based solely on the preoperative anteroposterior (AP) X-ray view. The model was trained and validated over six epochs to optimize its predictive accuracy. Results: The logistic regression yielded an accuracy of 66.3% in predicting the surgical outcome based on patient parameters. The deep learning model demonstrated remarkable predictive accuracy, achieving a success rate of 93.6%, suggesting its potential as a reliable tool for guiding clinical decision-making in scaphoid nonunion management. Conclusions: The findings of this study indicate that the preoperative AP X-ray of a scaphoid nonunion provides sufficient information to predict the likelihood of surgical success when analyzed using our deep learning model. This approach has the potential to streamline decision-making and reduce reliance on extensive imaging and prolonged conservative treatment. Full article
(This article belongs to the Special Issue Advances and Updates in Hand Surgery)
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6 pages, 846 KB  
Brief Report
Scaphoid Fat Stripe Sign: Is It a Reliable Radiological Sign of Scaphoid Fracture in Children?
by Pavle Manic, Stéphanie Schizas, Pierre-Yves Zambelli and Eleftheria Samara
Children 2025, 12(1), 86; https://doi.org/10.3390/children12010086 - 13 Jan 2025
Viewed by 1825
Abstract
Objectives: The scaphoid fat pad stripe (SFS) is a radiological sign first described in 1975 as a line of relative lucency lying parallel to the lateral border of the scaphoid, with slight convexity toward it, and it is optimally demonstrated on postero-anterior and [...] Read more.
Objectives: The scaphoid fat pad stripe (SFS) is a radiological sign first described in 1975 as a line of relative lucency lying parallel to the lateral border of the scaphoid, with slight convexity toward it, and it is optimally demonstrated on postero-anterior and oblique views with ulnar deviation of the carpus. The obliteration or displacement of this line is commonly present in acute fractures of the scaphoid, radial styloid process, and proximal first metacarpus. The aim of this observational study is to investigate the supportive value of the fat stripe sign (SFS) in the diagnosis of scaphoid fractures in the pediatric population. Methods: This is a monocentric, retrospective study of all patients referred to the Pediatric Traumatology Unit of a tertiary hospital from the Emergency Department with clinical suspicion of scaphoid fracture without visible fracture in the initial X-ray. Radiological reports for CT and MRIs were recorded, and the initial X-rays were blindly reviewed by a pediatric orthopedic fellowship-accredited surgeon for the presence of an abnormal scaphoid fat pad stripe sign and the presence of a fracture line in the initial X-rays. Results: The results of the blind interpretation of the initial X-rays for the fat stripe sign showed 86% sensitivity and 58% specificity, with the negative predictive value reaching 92%. Conclusions: The scaphoid fat stripe sign can be used as an adjacent in the diagnosis of an occult scaphoid fracture in children or adolescents. Its high negative predictive value, if confirmed in larger studies, can be an element used to exclude scaphoid fracture and consequently avoid unnecessary immobilizations and health costs. Full article
(This article belongs to the Section Pediatric Radiology)
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20 pages, 6558 KB  
Article
The Detection and Classification of Scaphoid Fractures in Radiograph by Using a Convolutional Neural Network
by Tai-Hua Yang, Yung-Nien Sun, Rong-Shiang Li and Ming-Huwi Horng
Diagnostics 2024, 14(21), 2425; https://doi.org/10.3390/diagnostics14212425 - 30 Oct 2024
Viewed by 4479
Abstract
Objective: Scaphoid fractures, particularly occult and non-displaced fractures, are difficult to detect using traditional X-ray methods because of their subtle appearance and variability in bone density. This study proposes a two-stage CNN approach to detect and classify scaphoid fractures using anterior–posterior (AP) and [...] Read more.
Objective: Scaphoid fractures, particularly occult and non-displaced fractures, are difficult to detect using traditional X-ray methods because of their subtle appearance and variability in bone density. This study proposes a two-stage CNN approach to detect and classify scaphoid fractures using anterior–posterior (AP) and lateral (LA) X-ray views for more accurate diagnosis. Methods: This study emphasizes the use of multi-view X-ray images (AP and LA views) to improve fracture detection and classification. The multi-view fusion module helps integrate information from both views to enhance detection accuracy, particularly for occult fractures that may not be visible in a single view. The proposed method includes two stages, which are stage 1: detect the scaphoid bone using Faster RCNN and a Feature Pyramid Network (FPN) for region proposal and small object detection. The detection accuracy for scaphoid localization is 100%, with Intersection over Union (IoU) scores of 0.8662 for AP views and 0.8478 for LA views. And stage 2: perform fracture classification using a ResNet backbone and FPN combined with a multi-view fusion module to combine features from both AP and LA views. This stage achieves a classification accuracy of 89.94%, recall of 87.33%, and precision of 90.36%. Results: The proposed model performs well in both scaphoid bone detection and fracture classification. The multi-view fusion approach significantly improves recall and accuracy in detecting fractures compared to single-view approaches. In scaphoid detection, both AP and LA views achieved 100% detection accuracy. In fracture detection, using multi-view fusion, the accuracy for AP views reached 87.16%, and for LA views, it reached 83.83%. Conclusions: The multi-view fusion model effectively improves the detection of scaphoid fractures, particularly in cases of occult and non-displaced fractures. The model provides a reliable, automated approach to assist clinicians in detecting and diagnosing scaphoid fractures more efficiently. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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21 pages, 1133 KB  
Review
An Umbrella Review and Updated Meta-Analysis of Imaging Modalities in Occult Scaphoid and Hip and Femoral Fractures
by Patricia Jorisal, Callistus Bruce Henfry Sulay and Gilbert Sterling Octavius
J. Clin. Med. 2024, 13(13), 3769; https://doi.org/10.3390/jcm13133769 - 27 Jun 2024
Cited by 1 | Viewed by 2695
Abstract
Background: Occult fractures may cause multiple morbidities. If occult fractures were detected earlier, complications may be preventable. This umbrella review and updated meta-analysis will aim to evaluate the use of imaging modalities in detecting occult scaphoid and hip fractures. Methods: The protocol for [...] Read more.
Background: Occult fractures may cause multiple morbidities. If occult fractures were detected earlier, complications may be preventable. This umbrella review and updated meta-analysis will aim to evaluate the use of imaging modalities in detecting occult scaphoid and hip fractures. Methods: The protocol for this study is available in the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42024525388). The literature search started and ended on 17 March 2024. We searched seven academic databases: MEDLINE, Cochrane Library, Pubmed, Science Direct, Google Scholar, WHO International Clinical Trials Registry Platform, and The Joanna Briggs Institute (JBI) database. The meta-analysis was conducted with the STATA program using the “midas” command. Results: There are four systematic reviews evaluating occult hip and femoral fractures with 6174 patients and two reviews evaluating occult scaphoid fractures with 1355 patients. The prevalence of occult scaphoid fracture and occult hip and femoral fractures is 23.87% (95% CI 18.25–29.49) and 44.8% (95% CI 39.38–51.4), respectively. Magnetic resonance imaging (MRI) had the best posterior probability of positive likelihood ratio (LR+) with 95% and 96% and negative likelihood ratio (LR-) with 0.15% and 1% for both occult scaphoid and hip fractures, respectively, assuming a 25% baseline. MRI could both confirm and exclude occult hip fractures while it can only confirm occult scaphoid fractures. Bone scans are inappropriate for either type of occult fractures The level of evidence for occult scaphoid fracture is weak while it is suggestive for occult hip fractures. Conclusion: The findings strengthen the use of MRI after an initially negative radiograph fracture for occult hip and femoral fractures, with a CT scan as a viable second option. Full article
(This article belongs to the Special Issue Acute Trauma and Trauma Care in Orthopedics)
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18 pages, 2469 KB  
Article
Deep Learning-Based Surgical Treatment Recommendation and Nonsurgical Prognosis Status Classification for Scaphoid Fractures by Automated X-ray Image Recognition
by Ja-Hwung Su, Yu-Cheng Tung, Yi-Wen Liao, Hung-Yu Wang, Bo-Hong Chen, Ching-Di Chang, Yu-Fan Cheng, Wan-Ching Chang and Chu-Yu Chin
Biomedicines 2024, 12(6), 1198; https://doi.org/10.3390/biomedicines12061198 - 28 May 2024
Cited by 1 | Viewed by 1760
Abstract
Biomedical information retrieval for diagnosis, treatment and prognosis has been studied for a long time. In particular, image recognition using deep learning has been shown to be very effective for cancers and diseases. In these fields, scaphoid fracture recognition is a hot topic [...] Read more.
Biomedical information retrieval for diagnosis, treatment and prognosis has been studied for a long time. In particular, image recognition using deep learning has been shown to be very effective for cancers and diseases. In these fields, scaphoid fracture recognition is a hot topic because the appearance of scaphoid fractures is not easy to detect. Although there have been a number of recent studies on this topic, no studies focused their attention on surgical treatment recommendations and nonsurgical prognosis status classification. Indeed, a successful treatment recommendation will assist the doctor in selecting an effective treatment, and the prognosis status classification will help a radiologist recognize the image more efficiently. For these purposes, in this paper, we propose potential solutions through a comprehensive empirical study assessing the effectiveness of recent deep learning techniques on surgical treatment recommendation and nonsurgical prognosis status classification. In the proposed system, the scaphoid is firstly segmented from an unknown X-ray image. Next, for surgical treatment recommendation, the fractures are further filtered and recognized. According to the recognition result, the surgical treatment recommendation is generated. Finally, even without sufficient fracture information, the doctor can still make an effective decision to opt for surgery or not. Moreover, for nonsurgical patients, the current prognosis status of avascular necrosis, non-union and union can be classified. The related experimental results made using a real dataset reveal that the surgical treatment recommendation reached 80% and 86% in accuracy and AUC (Area Under the Curve), respectively, while the nonsurgical prognosis status classification reached 91% and 96%, respectively. Further, the methods using transfer learning and data augmentation can bring out obvious improvements, which, on average, reached 21.9%, 28.9% and 5.6%, 7.8% for surgical treatment recommendations and nonsurgical prognosis image classification, respectively. Based on the experimental results, the recommended methods in this paper are DenseNet169 and ResNet50 for surgical treatment recommendation and nonsurgical prognosis status classification, respectively. We believe that this paper can provide an important reference for future research on surgical treatment recommendation and nonsurgical prognosis classification for scaphoid fractures. Full article
(This article belongs to the Special Issue Artificial Intelligence Applications in Cancer and Other Diseases)
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12 pages, 665 KB  
Systematic Review
Bilateral Scaphoid Fractures: A Systematic Literature Review
by Lorenzo D’Itri, Maria Serena Gattuso, Claudio Domenico Cobisi, Massimo Ferruzza, Ludovico Lucenti and Lawrence Camarda
J. Pers. Med. 2024, 14(4), 424; https://doi.org/10.3390/jpm14040424 - 16 Apr 2024
Cited by 1 | Viewed by 2879
Abstract
Bilateral scaphoid fractures are rare lesions, warranting a review to synthesize current knowledge, identify gaps, and suggest research directions. Two authors, adhering to PRISMA guidelines, in January 2024 identified 16 case reports (1976–2023). Data extraction included demographics, injury mechanisms, associated injuries, fracture sites, [...] Read more.
Bilateral scaphoid fractures are rare lesions, warranting a review to synthesize current knowledge, identify gaps, and suggest research directions. Two authors, adhering to PRISMA guidelines, in January 2024 identified 16 case reports (1976–2023). Data extraction included demographics, injury mechanisms, associated injuries, fracture sites, treatments, and outcomes. Among 121 initial outcomes, 16 articles met the criteria, predominantly affecting young people (93.75% males, mean age 22 years). High-energy traumas (75%) often caused associated wrist injuries (68.75%). Most fractures required surgical intervention (68.75%), primarily headless compression screws. Bilateral scaphoid fractures, which are rare but associated with high-energy traumas, commonly involve wrist injuries. Surgical management is often necessary, yielding better outcomes with fewer complications. Further research is essential to understand the epidemiology, optimal management, and long-term results. Early diagnosis and appropriate treatment are crucial for preventing complications and ensuring favorable patient outcomes. Full article
(This article belongs to the Special Issue Personalized Management in Orthopedics and Traumatology)
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8 pages, 8173 KB  
Case Report
Fracture Dislocation of the Pisiform Bone in 14-Year-Old Boy—A Case Report
by Ondřej Procházka, Tomás Sánchez and Karolína Kašpárková
Medicina 2024, 60(4), 532; https://doi.org/10.3390/medicina60040532 - 25 Mar 2024
Cited by 1 | Viewed by 6842
Abstract
We present the case of a 14-year-old patient who suffered fracture dislocation of the pisiform bone (PB) along with fractures of the scaphoid, proximal radius, and proximal phalanx of the thumb due to high-energy trauma directly to the extended wrist. This combination of [...] Read more.
We present the case of a 14-year-old patient who suffered fracture dislocation of the pisiform bone (PB) along with fractures of the scaphoid, proximal radius, and proximal phalanx of the thumb due to high-energy trauma directly to the extended wrist. This combination of fractures has not been previously reported in the literature. Currently, there is no consensus in the literature regarding the optimal treatment approach for such cases. In our management, initial attempts at closed and open reduction were unsuccessful, leading to the decision for primary pisiformectomy. Our report includes a follow-up of 3.5 years, demonstrating a very good outcome. Based on this case and a few similar published cases, primary pisiformectomy appears to be a viable and well-accepted option, particularly among young patients. Additionally, we conducted a review of radiographic criteria and management strategies for this specific injury and related conditions. Full article
(This article belongs to the Special Issue Clinical Anatomy Implications and Musculoskeletal Disorders)
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11 pages, 3545 KB  
Article
Deep Convolutional Neural Networks Provide Motion Grading for High-Resolution Peripheral Quantitative Computed Tomography of the Scaphoid
by Stefan Benedikt, Philipp Zelger, Lukas Horling, Kerstin Stock, Johannes Pallua, Michael Schirmer, Gerald Degenhart, Alexander Ruzicka and Rohit Arora
Diagnostics 2024, 14(5), 568; https://doi.org/10.3390/diagnostics14050568 - 6 Mar 2024
Cited by 1 | Viewed by 1656
Abstract
In vivo high-resolution peripheral quantitative computed tomography (HR-pQCT) studies on bone characteristics are limited, partly due to the lack of standardized and objective techniques to describe motion artifacts responsible for lower-quality images. This study investigates the ability of such deep-learning techniques to assess [...] Read more.
In vivo high-resolution peripheral quantitative computed tomography (HR-pQCT) studies on bone characteristics are limited, partly due to the lack of standardized and objective techniques to describe motion artifacts responsible for lower-quality images. This study investigates the ability of such deep-learning techniques to assess image quality in HR-pQCT datasets of human scaphoids. In total, 1451 stacks of 482 scaphoid images from 53 patients, each with up to six follow-ups within one year, and each with one non-displaced fractured and one contralateral intact scaphoid, were independently graded by three observers using a visual grading scale for motion artifacts. A 3D-CNN was used to assess image quality. The accuracy of the 3D-CNN to assess the image quality compared to the mean results of three skilled operators was between 92% and 96%. The 3D-CNN classifier reached an ROC-AUC score of 0.94. The average assessment time for one scaphoid was 2.5 s. This study demonstrates that a deep-learning approach for rating radiological image quality provides objective assessments of motion grading for the scaphoid with a high accuracy and a short assessment time. In the future, such a 3D-CNN approach can be used as a resource-saving and cost-effective tool to classify the image quality of HR-pQCT datasets in a reliable, reproducible and objective way. Full article
(This article belongs to the Special Issue Artificial Intelligence in Biomedical Diagnostics and Analysis)
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27 pages, 11756 KB  
Article
Porous Mg–Hydroxyapatite Composite Incorporated with Aloe barbadensis Miller for Scaphoid Fracture Fixation: A Natural Drug Loaded Orthopedic Implant
by Divyanshu Aggarwal, Siddharth Sharma and Manoj Gupta
Appl. Sci. 2024, 14(4), 1512; https://doi.org/10.3390/app14041512 - 13 Feb 2024
Cited by 1 | Viewed by 1837
Abstract
The current study focused on developing a biodegradable implant composite material that could work in a multitude of applications. The fabricated composite showcases a porous matrix of Mg–hydroxyapatite developed through the spacer-holder technique. The composite was incorporated with a natural medicinal plant, i.e., [...] Read more.
The current study focused on developing a biodegradable implant composite material that could work in a multitude of applications. The fabricated composite showcases a porous matrix of Mg–hydroxyapatite developed through the spacer-holder technique. The composite was incorporated with a natural medicinal plant, i.e., Aloe barbadensis miller, commonly known as the Aloe vera plant. The final composite was enveloped under a thin layer of PLA to work as an encapsulated drug as well as a composite material for implant applications. Further, the mechanical and microstructural properties were analyzed along with corrosion analysis through the weight loss method and pH change. The experiments showed an improvement in the corrosion rate when tested under cell culture medium. The antibacterial rates were experimented with under different aloe vera concentrations against Gram-positive B. subtilis and Gram-negative E. coli, and finally, a minimum inhibitory value was formulated for further experimentations. Hemocompatibility and surface wettability tests were also performed, which revealed improved surface hydrophilicity with a reduced hemolysis rate. An in vitro cell viability analysis was performed against the MG63 osteoblast cell line to indicate the cytotoxicity and cytocompatibility of the samples. This research proposed a novel composite material that provides antibacterial and non-toxic properties and retains its strength under a physiological environment. Full article
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13 pages, 2139 KB  
Article
Treatment of Scaphoid Non-Unions with Custom-Made 3D-Printed Titanium Partial and Total Scaphoid Prostheses and Scaphoid Interosseous Ligament Reconstruction
by Alessio Cioffi, Giuseppe Rovere, Francesco Bosco, Ennio Sinno, Leonardo Stramazzo, Francesco Liuzza, Antonio Ziranu, Michele Romeo, Giulio Edoardo Vigni, Nicolò Galvano, Giulio Maccauro, Pasquale Farsetti, Mario Igor Rossello and Lawrence Camarda
Healthcare 2023, 11(24), 3123; https://doi.org/10.3390/healthcare11243123 - 8 Dec 2023
Cited by 5 | Viewed by 2520
Abstract
Purpose: Treatment of scaphoid fracture sequelae is still an unsolved problem in hand surgery. Custom-made 3D-printed titanium partial and total scaphoid prosthesis and scaphoid interosseous ligament reconstruction (SLIL) are performed in cases of non-union and isolated aseptic necrosis of the proximal scaphoid pole [...] Read more.
Purpose: Treatment of scaphoid fracture sequelae is still an unsolved problem in hand surgery. Custom-made 3D-printed titanium partial and total scaphoid prosthesis and scaphoid interosseous ligament reconstruction (SLIL) are performed in cases of non-union and isolated aseptic necrosis of the proximal scaphoid pole and when it is impossible to save the scaphoid bone, respectively. This study aims to evaluate the clinical, functional and radiographic results after these two prosthesis implantations. Methods: Between January 2019 and July 2020, nine partial and ten total scaphoid prostheses were implanted using custom-made 3D-printed titanium implants. Evaluation criteria included carpal height ratio (CHR), radioscaphoid angle, wrist extension and flexion, radial deviation and ulnar deviation of the wrist, grip strength and pinch strength, Visual Analogue Scale (VAS), the Disabilities of Arm, Shoulder, and Hand (DASH) score, and the Patient-Rated Wrist Evaluation (PRWE). Results: Clinical, functional, and radiographic improvements were found in all outcomes analyzed for both patient groups. The VAS pain scale obtained the most remarkable improvement at the one-year follow-up. The results of the DASH scores and the PRWE were good, with a great rate of patient satisfaction at the end of the follow-up. SLIL reconstruction also provided excellent stability and prevented a mid-carpal bone collapse in the short- and medium-term follow-up. Conclusions: A custom-made 3D-printed titanium partial or total scaphoid prosthesis is a viable solution for patients with scaphoid non-union and necrosis or complete scaphoid destruction in whom previous conservative or surgical treatment has failed. Full article
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11 pages, 1569 KB  
Article
Clinical Validation of an Artificial Intelligence Model for Detecting Distal Radius, Ulnar Styloid, and Scaphoid Fractures on Conventional Wrist Radiographs
by Kyu-Chong Lee, In Cheul Choi, Chang Ho Kang, Kyung-Sik Ahn, Heewon Yoon, Jae-Joon Lee, Baek Hyun Kim and Euddeum Shim
Diagnostics 2023, 13(9), 1657; https://doi.org/10.3390/diagnostics13091657 - 8 May 2023
Cited by 18 | Viewed by 3707
Abstract
This study aimed to assess the feasibility and performance of an artificial intelligence (AI) model for detecting three common wrist fractures: distal radius, ulnar styloid process, and scaphoid. The AI model was trained with a dataset of 4432 images containing both fractured and [...] Read more.
This study aimed to assess the feasibility and performance of an artificial intelligence (AI) model for detecting three common wrist fractures: distal radius, ulnar styloid process, and scaphoid. The AI model was trained with a dataset of 4432 images containing both fractured and non-fractured wrist images. In total, 593 subjects were included in the clinical test. Two human experts independently diagnosed and labeled the fracture sites using bounding boxes to build the ground truth. Two novice radiologists also performed the same task, both with and without model assistance. The sensitivity, specificity, accuracy, and area under the curve (AUC) were calculated for each wrist location. The AUC for detecting distal radius, ulnar styloid, and scaphoid fractures per wrist were 0.903 (95% C.I. 0.887–0.918), 0.925 (95% C.I. 0.911–0.939), and 0.808 (95% C.I. 0.748–0.967), respectively. When assisted by the AI model, the scaphoid fracture AUC of the two novice radiologists significantly increased from 0.75 (95% C.I. 0.66–0.83) to 0.85 (95% C.I. 0.77–0.93) and from 0.71 (95% C.I. 0.62–0.80) to 0.80 (95% C.I. 0.71–0.88), respectively. Overall, the developed AI model was found to be reliable for detecting wrist fractures, particularly for scaphoid fractures, which are commonly missed. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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