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19 pages, 17439 KB  
Article
Dual-Polarization Radar Deception Jamming Method Based on Joint Fast-Slow-Time Polarization Modulation
by Yongfei Zhang, Yong Yang, Chao Hu, Jingwen Han and Boyu Yang
Remote Sens. 2025, 17(17), 2952; https://doi.org/10.3390/rs17172952 (registering DOI) - 25 Aug 2025
Abstract
To address the vulnerability of single-polarization deception jamming and simply modulated dual-polarization jamming to discrimination by dual-polarization radars, this paper proposes a deception jamming method based on joint fast–slow-time polarization modulation (FSPMJ). First, in the slow-time domain (across multiple pulses), the polarization azimuth [...] Read more.
To address the vulnerability of single-polarization deception jamming and simply modulated dual-polarization jamming to discrimination by dual-polarization radars, this paper proposes a deception jamming method based on joint fast–slow-time polarization modulation (FSPMJ). First, in the slow-time domain (across multiple pulses), the polarization azimuth of the jamming signal is designed according to the target’s polarization ratio distribution. Subsequently, with the target polarization degree as the optimization objective, the polarization phase difference of the jamming signal is solved using an interior-point optimization algorithm, establishing the initial polarization state for each pulse. This process is iterated to design the polarization state for the first half of each pulse. Then, in the fast-time domain (within a single pulse), a polarization state orthogonal to the pre-generated first-half state, is constructed to serve as the polarization state for the latter half of each pulse. Finally, the effectiveness of the proposed method is validated through combined simulation and measured data using a Support Vector Machine (SVM) algorithm. Results demonstrate that compared to single-polarization deception jamming and existing polarization-modulated jamming, this method reduces the false target discrimination rate of dual-polarization radars by 35.4% without requiring complex target scattering matrices. Full article
(This article belongs to the Special Issue Radar Data Processing and Analysis)
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20 pages, 3408 KB  
Article
Spectral-Spatial Fusion for Soybean Quality Evaluation Using Hyperspectral Imaging
by Md Bayazid Rahman, Ahmad Tulsi and Abdul Momin
AgriEngineering 2025, 7(9), 274; https://doi.org/10.3390/agriengineering7090274 (registering DOI) - 25 Aug 2025
Abstract
Accurate postharvest quality evaluation of soybeans is essential for preserving product value and meeting industry standards. Traditional inspection methods are often inconsistent, labor-intensive, and unsuitable for high-throughput operations. This study presents a non-destructive soybean classification approach using a simplified reflectance-mode hyperspectral imaging system [...] Read more.
Accurate postharvest quality evaluation of soybeans is essential for preserving product value and meeting industry standards. Traditional inspection methods are often inconsistent, labor-intensive, and unsuitable for high-throughput operations. This study presents a non-destructive soybean classification approach using a simplified reflectance-mode hyperspectral imaging system equipped with a single light source, eliminating the complexity and maintenance demands of dual-light configurations used in prior studies. A spectral–spatial data fusion strategy was developed to classify harvested soybeans into four categories: normal, split, diseased, and foreign materials such as stems and pods. The dataset consisted of 1140 soybean samples distributed across these four categories, with spectral reflectance features and spatial texture attributes extracted from each sample. These features were combined to form a unified feature representation for use in classification. Among multiple machine learning classifiers evaluated, Linear Discriminant Analysis (LDA) achieved the highest performance, with approximately 99% accuracy, 99.05% precision, 99.03% recall and 99.03% F1-score. When evaluated independently, spectral features alone resulted in 98.93% accuracy, while spatial features achieved 78.81%, highlighting the benefit of the fusion strategy. Overall, this study demonstrates that a single-illumination HSI system, combined with spectral–spatial fusion and machine learning, offers a practical and potentially scalable approach for non-destructive soybean quality evaluation, with applicability in automated industrial processing environments. Full article
(This article belongs to the Special Issue Latest Research on Post-Harvest Technology to Reduce Food Loss)
11 pages, 8530 KB  
Article
Towards Manufacturing High-Quality Film-Cooling Holes Using Femtosecond Laser Combined with Abrasive Flow
by Lifei Wang, Zhen Wang, Junjie Xu, Wanrong Zhao and Zhen Zhang
Micromachines 2025, 16(9), 973; https://doi.org/10.3390/mi16090973 (registering DOI) - 25 Aug 2025
Abstract
Film-cooling holes are the key cooling structures of turbine blades, and there are still great challenges in manufacturing high-quality film-cooling holes. Although abrasive flow machining can be used as a post-processing technique to optimize the quality of film-cooling holes, its action process and [...] Read more.
Film-cooling holes are the key cooling structures of turbine blades, and there are still great challenges in manufacturing high-quality film-cooling holes. Although abrasive flow machining can be used as a post-processing technique to optimize the quality of film-cooling holes, its action process and influence mechanism have not been systematically studied. Herein, the drilling method of femtosecond laser combined with abrasive flow is studied in detail. Moreover, for comparison, the drilling methods of single femtosecond laser, single electrical discharge machining, and electrical discharge machining combined with abrasive flow are also discussed. The microstructure and composition distribution of the hole walls before and after abrasive flow machining were systematically characterized, indicating that abrasive flow can effectively remove the recast layer and cause local plastic deformation. Due to the surface hardening and non-uniform residual stress caused by abrasive impact, abrasive flow machining can increase the high-temperature endurance time of film-cooling holes while reducing the elongation. The combination of femtosecond laser and abrasive flow machining demonstrates the best high-temperature mechanical properties, with the endurance time and elongation reaching 136.15 h and 12.1%, respectively. The fracture mechanisms of different drilling methods are further discussed in detail. The research results provide theoretical guidance for the manufacturing of high-quality film-cooling holes through the composite processing of femtosecond laser and abrasive flow. Full article
(This article belongs to the Special Issue Recent Advances in Micro/Nanofabrication, 2nd Edition)
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10 pages, 1390 KB  
Proceeding Paper
Students’ Success Rate Enhancement in an Electrical Machines Subject Through a Hybrid Flipped Classroom–Socratic Method
by Mbika Muteba
Eng. Proc. 2025, 104(1), 12; https://doi.org/10.3390/engproc2025104012 (registering DOI) - 25 Aug 2025
Abstract
In this paper, a hybrid flipped classroom–Socratic method (HFC-SBM) is proposed as an active and effective method of teaching and learning to enhance the success rate in the subject of electrical machines. The proposed method was applied in the third year of a [...] Read more.
In this paper, a hybrid flipped classroom–Socratic method (HFC-SBM) is proposed as an active and effective method of teaching and learning to enhance the success rate in the subject of electrical machines. The proposed method was applied in the third year of a Bachelor of Engineering Technology program. Most students were new to the subject of electrical machines and did not have any prior knowledge of the principle of energy conversion in electrical machines. The traditional method (TRM), the flipped classroom method (FCM), and the Socratic-based method (SBM) were applied and then compared with the proposed HFC-SBM. The students were assessed each time they completed a specific teaching and learning method. The assessment results revealed that the proposed HFC-SBM improved the students’ success rate tremendously by 300%, 160%, and 80% when compared to the TRM, FCM, and SBM, respectively. A single-factor Analysis of Variance (ANOVA) test has been carried out on the statistical data to assess the significance of the different teaching and learning methods on the students’ success rate. Full article
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20 pages, 21382 KB  
Article
Comparative Performance Analysis of Heterogeneous Ensemble Learning Models for Multi-Satellite Fusion GNSS-IR Soil Moisture Retrieval
by Yao Jiang, Rui Zhang, Hang Jiang, Bo Zhang, Kangyi Chen, Jichao Lv, Jie Chen and Yunfan Song
Land 2025, 14(9), 1716; https://doi.org/10.3390/land14091716 (registering DOI) - 25 Aug 2025
Abstract
Given the complexity of near-surface soil moisture retrieval, a single machine learning algorithm often struggles to capture the intricate relationships among multiple features, resulting in limited generalization and robustness. To address this issue, this study proposes a multi-satellite fusion GNSS-IR soil moisture retrieval [...] Read more.
Given the complexity of near-surface soil moisture retrieval, a single machine learning algorithm often struggles to capture the intricate relationships among multiple features, resulting in limited generalization and robustness. To address this issue, this study proposes a multi-satellite fusion GNSS-IR soil moisture retrieval method based on heterogeneous ensemble machine learning models. Specifically, two heterogeneous ensemble learning strategies (Bagging and Stacking) are combined with three base learners, Back Propagation Neural Network (BPNN), Random Forest (RF), and Support Vector Machine (SVM), to construct eight ensemble GNSS-IR soil moisture retrieval models. The models are validated using data from GNSS stations P039, P041, and P043 within the Plate Boundary Observatory (PBO) network. Their retrieval performance is compared against that of individual machine learning models and a deep learning model (Multilayer Perceptron, MLP), enabling an optimized selection of algorithms and model architectures. Results show that the Stacking-based models significantly outperform those based on Bagging in terms of retrieval accuracy. Among them, the Stacking (BPNN-RF-SVM) model achieves the highest performance across all three stations, with R of 0.903, 0.904, and 0.917, respectively. These represent improvements of at least 2.2%, 2.8%, and 2.1% over the best-performing base models. Therefore, the Stacking (BPNN-RF-SVM) model is identified as the optimal retrieval model. This work aims to contribute to the development of high-accuracy, real-time monitoring methods for near-surface soil moisture. Full article
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21 pages, 2893 KB  
Article
Intelligent Fault Diagnosis System for Running Gear of High-Speed Trains
by Shuai Yang, Guoliang Gao, Ziyang Wang, Shengfeng Zeng, Yikai Ouyang and Guanglei Zhang
Sensors 2025, 25(17), 5269; https://doi.org/10.3390/s25175269 - 24 Aug 2025
Abstract
Conventional rail transit train running gear fault diagnosis mainly depends on routine maintenance inspections and manual judgment. However, these approaches lack robustness under complex operational environments and elevated noise levels, rendering them inadequate for real-time performance and the rigorous accuracy standards demanded by [...] Read more.
Conventional rail transit train running gear fault diagnosis mainly depends on routine maintenance inspections and manual judgment. However, these approaches lack robustness under complex operational environments and elevated noise levels, rendering them inadequate for real-time performance and the rigorous accuracy standards demanded by modern rail transit systems. Furthermore, many existing deep learning–based methods suffer from inherent limitations in feature extraction or incur prohibitive computational costs when processing multivariate time series data. This study represents one of the early efforts to introduce the TimesNet time series modeling framework into the domain of fault diagnosis for rail transit train running gear. By utilizing an innovative multi-period decomposition strategy and a mechanism for reshaping one-dimensional data into two-dimensional tensors, the framework enables advanced temporal-spatial representation of time series data. Algorithm validation is performed on both the high-speed train running gear bearing fault dataset and the multi-mode fault diagnosis datasets of gearbox under variable working conditions. The TimesNet model exhibits outstanding diagnostic performance on both datasets, achieving a diagnostic accuracy of 91.7% on the high-speed train bearing fault dataset. Embedded deployment experiments demonstrate that single-sample inference is completed within 70.3 ± 5.8 ms, thereby satisfying the real-time monitoring requirement (<100 ms) with a 100% success rate over 50 consecutive tests. The two-dimensional reshaping approach inherent to TimesNet markedly enhances the capacity of the model to capture intrinsic periodic structures within multivariate time series data, presenting a novel paradigm for the intelligent fault diagnosis of complex mechanical systems in train running gears. The integrated human–machine interaction system includes a comprehensive closed-loop process encompassing detection, diagnosis, and decision-making, thereby laying a robust foundation for the continued development of train running gear predictive maintenance technologies. Full article
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20 pages, 3413 KB  
Review
Design, Deposition, Performance Evaluation, and Modulation Analysis of Nanocoatings for Cutting Tools: A Review
by Qi Xi, Siqi Huang, Jiang Chang, Dong Wang, Xiangdong Liu, Nuan Wen, Xi Cao and Yuguang Lv
Inorganics 2025, 13(9), 281; https://doi.org/10.3390/inorganics13090281 - 24 Aug 2025
Abstract
With the rapid development of advanced machining technologies such as high-speed cutting, dry cutting, and ultra-precision cutting, as well as the widespread application of various difficult-to-machine materials, the surface degradation problems such as wear, oxidation, and delamination faced by tools in the service [...] Read more.
With the rapid development of advanced machining technologies such as high-speed cutting, dry cutting, and ultra-precision cutting, as well as the widespread application of various difficult-to-machine materials, the surface degradation problems such as wear, oxidation, and delamination faced by tools in the service process have become increasingly prominent, seriously restricting the performance and service life of tools. Nanocoatings, with their distinct nano-effects, provide superior hardness, thermal stability, and tribological properties, making them an effective solution for cutting tools in increasingly demanding working environments. For example, the hardness of the CrAlN/TiSiN nano-multilayer coating can reach 41.59 GPa, which is much higher than that of a single CrAlN coating (34.5–35.8 GPa). This paper summarizes the most common nanocoating material design, coating deposition technologies, performance evaluation indicators, and characterization methods currently used in cutting tools. It also discusses how to improve nanocoating performance using modulation analysis of element content, coating composition, geometric structure, and coating thickness. Finally, this paper considers the future development of nanocoatings for cutting tools in light of recent research hotspots. Full article
(This article belongs to the Special Issue Novel Inorganic Coatings and Thin Films)
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16 pages, 1085 KB  
Article
Predicting Regional Cerebral Blood Flow Using Voxel-Wise Resting-State Functional MRI
by Hongjie Ke, Bhim M. Adhikari, Yezhi Pan, David B. Keator, Daniel Amen, Si Gao, Yizhou Ma, Paul M. Thompson, Neda Jahanshad, Jessica A. Turner, Theo G. M. van Erp, Mohammed R. Milad, Jair C. Soares, Vince D. Calhoun, Juergen Dukart, L. Elliot Hong, Tianzhou Ma and Peter Kochunov
Brain Sci. 2025, 15(9), 908; https://doi.org/10.3390/brainsci15090908 - 23 Aug 2025
Viewed by 102
Abstract
Background: Regional cerebral blood flow (rCBF) is a putative biomarker for neuropsychiatric disorders, including major depressive disorder (MDD). Methods: Here, we show that rCBF can be predicted from resting-state functional MRI (rsfMRI) at the voxel level while correcting for partial volume averaging (PVA) [...] Read more.
Background: Regional cerebral blood flow (rCBF) is a putative biomarker for neuropsychiatric disorders, including major depressive disorder (MDD). Methods: Here, we show that rCBF can be predicted from resting-state functional MRI (rsfMRI) at the voxel level while correcting for partial volume averaging (PVA) artifacts. Cortical patterns of MDD-related CBF differences decoded from rsfMRI using a PVA-corrected approach showed excellent agreement with CBF measured using single-photon emission computed tomography (SPECT) and arterial spin labeling (ASL). A support vector machine algorithm was trained to decode cortical voxel-wise CBF from temporal and power-spectral features of voxel-level rsfMRI time series while accounting for PVA. Three datasets, Amish Connectome Project (N = 300; 179 M/121 F, both rsfMRI and ASL data), UK Biobank (N = 8396; 3097 M/5319 F, rsfMRI data), and Amen Clinics Inc. datasets (N = 372: N = 183 M/189 F, SPECT data), were used. Results: PVA-corrected CBF values predicted from rsfMRI showed significant correlation with the whole-brain (r = 0.54, p = 2 × 10−5) and 31 out of 34 regional (r = 0.33 to 0.59, p < 1.1 × 10−3) rCBF measures from 3D ASL. PVA-corrected rCBF values showed significant regional deficits in the UKBB MDD group (Cohen’s d = −0.30 to −0.56, p < 10−28), with the strongest effect sizes observed in the frontal and cingulate areas. The regional deficit pattern of MDD-related hypoperfusion showed excellent agreement with CBF deficits observed in the SPECT data (r = 0.74, p = 4.9 × 10−7). Consistent with previous findings, this new method suggests that perfusion signals can be predicted using voxel-wise rsfMRI signals. Conclusions: CBF values computed from widely available rsfMRI can be used to study the impact of neuropsychiatric disorders such as MDD on cerebral neurophysiology. Full article
(This article belongs to the Section Neurotechnology and Neuroimaging)
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19 pages, 2459 KB  
Article
Temporal-Alignment Cluster Identification and Relevance-Driven Feature Refinement for Ultra-Short-Term Wind Power Forecasting
by Yan Yan and Yan Zhou
Energies 2025, 18(17), 4477; https://doi.org/10.3390/en18174477 - 22 Aug 2025
Viewed by 136
Abstract
Ultra-short-term wind power forecasting is challenged by high volatility and complex temporal patterns, with traditional single-model approaches often failing to provide stable and accurate predictions under diverse operational scenarios. To address this issue, a framework based on the TCN-ELM hybrid model with temporal [...] Read more.
Ultra-short-term wind power forecasting is challenged by high volatility and complex temporal patterns, with traditional single-model approaches often failing to provide stable and accurate predictions under diverse operational scenarios. To address this issue, a framework based on the TCN-ELM hybrid model with temporal alignment clustering and feature refinement is proposed for ultra-short-term wind power forecasting. First, dynamic time warping (DTW)–K-means is applied to cluster historical power curves in the temporal alignment space, identifying consistent operational patterns and providing prior information for subsequent predictions. Then, a correlation-driven feature refinement method is introduced to weight and select the most representative meteorological and power sequence features within each cluster, optimizing the feature set for improved prediction accuracy. Next, a TCN-ELM hybrid model is constructed, combining the advantages of temporal convolutional networks (TCNs) in capturing sequential features and an extreme learning machine (ELM) in efficient nonlinear modelling. This hybrid approach enhances forecasting performance through their synergistic capabilities. Traditional ultra-short-term forecasting often focuses solely on historical power as input, especially with a 15 min resolution, but this study emphasizes reducing the time scale of meteorological forecasts and power samples to within one hour, aiming to improve the reliability of the forecasting model in handling sudden meteorological changes within the ultra-short-term time horizon. To validate the proposed framework, comparisons are made with several benchmark models, including traditional TCN, ELM, and long short-term memory (LSTM) networks. Experimental results demonstrate that the proposed framework achieves higher prediction accuracy and better robustness across various operational modes, particularly under high-variability scenarios, out-performing conventional models like TCN and ELM. The method provides a reliable technical solution for ultra-short-term wind power forecasting, grid scheduling, and power system stability. Full article
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24 pages, 5784 KB  
Article
Analysis and Optimization of Seeding Depth Control Parameters for Wide-Row Uniform Seeding Machines for Wheat
by Longfei Yang, Zenglu Shi, Yingxue Xue, Xuejun Zhang, Shenghe Bai, Jinshan Zhang and Yufei Jin
Agriculture 2025, 15(17), 1800; https://doi.org/10.3390/agriculture15171800 - 22 Aug 2025
Viewed by 183
Abstract
Seeding depth is a critical factor influencing the uniformity and vigor of wheat seedlings. To address inconsistent seeding depth in wide-row uniform seeding agricultural practices, we performed parameter analysis and optimization experiments on the seeding depth device of a wheat wide-row uniform seeding [...] Read more.
Seeding depth is a critical factor influencing the uniformity and vigor of wheat seedlings. To address inconsistent seeding depth in wide-row uniform seeding agricultural practices, we performed parameter analysis and optimization experiments on the seeding depth device of a wheat wide-row uniform seeding machine. The structure and working principle of the device were described, soil movement during operation was analyzed, and the models of rotary tiller blades and soil retention plates were investigated, identifying three key factors affecting seeding quality. Using the discrete element method, a model of the seeding depth device was established, and experiments were conducted, yielding the following conclusions: 1. Single-factor experiments were conducted under different seeding rate conditions, and it was found that the effects of various factors on the two indicators, namely the seeding depth qualification rate and the coefficient of variation for seeding uniformity, were regular. 2. A quadratic orthogonal rotated combination experiment with three factors determined the optimal structural parameters: tillage device penetration depth of 120 mm, rotational speed of 310 rpm, and soil retention plate inclination angle of 27°. Under these parameters, the seed depth qualification rate exceeded 90%, and the coefficient of variation for seed distribution uniformity was below 25%. 3. Field validation tests under optimal parameters confirmed a seed depth qualification rate ≥90% and variation for seed distribution uniformity was below ≤20.69%. 4. The error between simulation and field tests was ≤5%, validating the reliability of the discrete element method-based optimization for the seeding depth device. Full article
(This article belongs to the Section Agricultural Technology)
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21 pages, 7455 KB  
Article
A Method for Predicting Gas Well Productivity in Non-Dominant Multi-Layer Tight Sandstone Reservoirs of the Sulige Gas Field Based on Multi-Task Learning
by Dawei Liu, Shiqing Cheng, Han Wang and Yang Wang
Processes 2025, 13(8), 2666; https://doi.org/10.3390/pr13082666 - 21 Aug 2025
Viewed by 178
Abstract
This study proposes a multi-task learning-based production capacity prediction model aimed at improving the prediction accuracy for gas wells in multi-layer tight sandstone reservoirs of the Sulige gas field under small-sample conditions. The model integrates mutation theory and progressive hierarchical feature extraction to [...] Read more.
This study proposes a multi-task learning-based production capacity prediction model aimed at improving the prediction accuracy for gas wells in multi-layer tight sandstone reservoirs of the Sulige gas field under small-sample conditions. The model integrates mutation theory and progressive hierarchical feature extraction to achieve adaptive nonlinear feature extraction and autonomous feature selection tailored to different prediction tasks. Using the daily average production of each gas-bearing layer during the first month after well commencement and the cumulative production of each gas-bearing layer over the first year as targets, the model was applied to predict the production capacity of 66 gas wells. Compared with single-task models and classical machine learning methods, the proposed multi-task model significantly improves prediction accuracy, reducing the root mean squared error (RMSE) by over 40% and increasing the coefficient of determination (R2) to 0.82. Experimental results demonstrate the model’s effectiveness in environments with limited training data, offering a reliable approach for productivity prediction in complex multi-layer tight sandstone reservoirs. Full article
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12 pages, 1033 KB  
Article
A Time-Series Approach for Machine Learning-Based Patient-Specific Quality Assurance of Radiosurgery Plans
by Simone Buzzi, Pietro Mancosu, Andrea Bresolin, Pasqualina Gallo, Francesco La Fauci, Francesca Lobefalo, Lucia Paganini, Marco Pelizzoli, Giacomo Reggiori, Ciro Franzese, Stefano Tomatis, Marta Scorsetti, Cristina Lenardi and Nicola Lambri
Bioengineering 2025, 12(8), 897; https://doi.org/10.3390/bioengineering12080897 - 21 Aug 2025
Viewed by 158
Abstract
Stereotactic radiosurgery (SRS) for multiple brain metastases can be delivered with a single isocenter and non-coplanar arcs, achieving highly conformal dose distributions at the cost of extreme modulation of treatment machine parameters. As a result, SRS plans are at a higher risk of [...] Read more.
Stereotactic radiosurgery (SRS) for multiple brain metastases can be delivered with a single isocenter and non-coplanar arcs, achieving highly conformal dose distributions at the cost of extreme modulation of treatment machine parameters. As a result, SRS plans are at a higher risk of patient-specific quality assurance (PSQA) failure compared to standard treatments. This study aimed to develop a machine-learning (ML) model to predict the PSQA outcome (gamma passing rate, GPR) of SRS plans. Five hundred and ninety-two consecutive patients treated between 2020 and 2024 were selected. GPR analyses were performed using a 3%/1 mm criterion and a 95% action limit for each arc. Fifteen plan complexity metrics were used as input features to predict the GPR of an arc. A stratified and a time-series approach were employed to split the data into training (1555 arcs), validation (389 arcs), and test (486 arcs) sets. The ML model achieved a mean absolute error of 2.6% on the test set, with a 0.83% median residual value (measured/predicted). Lower values of the measured GPR tended to be overestimated. Sensitivity and specificity were 93% and 56%, respectively. ML models for virtual QA of SRS can be integrated into clinical practice, facilitating more efficient PSQA approaches. Full article
(This article belongs to the Special Issue Radiation Imaging and Therapy for Biomedical Engineering)
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30 pages, 3696 KB  
Article
Smart Formulation: AI-Driven Web Platform for Optimization and Stability Prediction of Compounded Pharmaceuticals Using KNIME
by Artur Grigoryan, Stefan Helfrich, Valentin Lequeux, Benjamine Lapras, Chloé Marchand, Camille Merienne, Fabien Bruno, Roseline Mazet and Fabrice Pirot
Pharmaceuticals 2025, 18(8), 1240; https://doi.org/10.3390/ph18081240 - 21 Aug 2025
Viewed by 134
Abstract
Background/Objectives: Smart Formulation is an artificial intelligence-based platform designed to predict the Beyond Use Dates (BUDs) of compounded oral solid dosage forms. The study aims to develop a decision-support tool for pharmacists by integrating molecular, formulation, and environmental parameters to assist in [...] Read more.
Background/Objectives: Smart Formulation is an artificial intelligence-based platform designed to predict the Beyond Use Dates (BUDs) of compounded oral solid dosage forms. The study aims to develop a decision-support tool for pharmacists by integrating molecular, formulation, and environmental parameters to assist in optimizing the stability of extemporaneous preparations. Methods: A tree ensemble regression model was trained using a curated dataset of 55 experimental BUD values collected from the Stabilis database. Each formulation was encoded with molecular descriptors, excipient composition, packaging type, and storage conditions. The model was implemented using the KNIME platform, allowing the integration of cheminformatics and machine learning workflows. After training, the model was used to predict BUDs for 3166 APIs under various formulation and storage scenarios. Results: The analysis revealed a significant impact of excipient type, number, and environmental conditions on API stability. APIs with lower LogP values generally exhibited greater stability, particularly when formulated with a single excipient. Excipients such as cellulose, silica, sucrose, and mannitol were associated with improved stability, whereas HPMC and lactose contributed to faster degradation. The use of two excipients instead of one frequently resulted in reduced BUDs, possibly due to moisture redistribution or phase separation effects. Conclusions: Smart Formulation represents a valuable contribution to computational pharmaceutics, bridging theoretical formulation design with practical compounding needs. The platform offers a scalable, cost-effective alternative to traditional stability testing and is already available for use by healthcare professionals. Its implementation in hospital and community pharmacies may help mitigate drug shortages, support formulation standardization, and improve patient care. Future developments will focus on real-time stability monitoring and adaptive learning for enhanced precision. Full article
(This article belongs to the Section Pharmaceutical Technology)
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22 pages, 9182 KB  
Article
Sensor Synergy in Bathymetric Mapping: Integrating Optical, LiDAR, and Echosounder Data Using Machine Learning
by Emre Gülher and Ugur Alganci
Remote Sens. 2025, 17(16), 2912; https://doi.org/10.3390/rs17162912 - 21 Aug 2025
Viewed by 278
Abstract
Bathymetry, the measurement of water depth and underwater terrain, is vital for scientific, commercial, and environmental applications. Traditional methods like shipborne echosounders are costly and inefficient in shallow waters due to limited spatial coverage and accessibility. Emerging technologies such as satellite imagery, drones, [...] Read more.
Bathymetry, the measurement of water depth and underwater terrain, is vital for scientific, commercial, and environmental applications. Traditional methods like shipborne echosounders are costly and inefficient in shallow waters due to limited spatial coverage and accessibility. Emerging technologies such as satellite imagery, drones, and spaceborne LiDAR offer cost-effective and efficient alternatives. This research explores integrating multi-sensor datasets to enhance bathymetric mapping in coastal and inland waters by leveraging each sensor’s strengths. The goal is to improve spatial coverage, resolution, and accuracy over traditional methods using data fusion and machine learning. Gülbahçe Bay in İzmir, Turkey, serves as the study area. Bathymetric modeling uses Sentinel-2, Göktürk-1, and aerial imagery with varying resolutions and sensor characteristics. Model calibration evaluates independent and integrated use of single-beam echosounder (SBE) and satellite-based LiDAR (ICESat-2) during training. After preprocessing, Random Forest and Extreme Gradient Boosting algorithms are applied for bathymetric inference. Results are assessed using accuracy metrics and IHO CATZOC standards, achieving A1 level for 0–10 m, A2/B for 0–15 m, and C level for 0–20 m depth intervals. Full article
(This article belongs to the Section Environmental Remote Sensing)
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27 pages, 1502 KB  
Review
Monitoring of Air Pollution from the Iron and Steel Industry: A Global Bibliometric Review
by Ekaterina Zolotova, Natalya Ivanova and Sezgin Ayan
Atmosphere 2025, 16(8), 992; https://doi.org/10.3390/atmos16080992 - 21 Aug 2025
Viewed by 207
Abstract
The iron and steel industry is one of the main industrial contributors to air pollution. The aim of our study is to analyze modern studies on air pollution by the iron and steel industry, as a result of which the geography and research [...] Read more.
The iron and steel industry is one of the main industrial contributors to air pollution. The aim of our study is to analyze modern studies on air pollution by the iron and steel industry, as a result of which the geography and research directions and the degree of development of current issues will be assessed, and the most cited articles and journals will be identified. A review of contemporary research (2018–2024) was conducted on the basis of articles with a digital object identifier (DOI) using machine learning methodologies (VOSviewer software version 1.6.20). The number of articles selected was 80. The heat map of study density clearly showed that the geographic distribution of studies was extremely uneven. A total of 65% of the studies were conducted in China, 9% in Nigeria, 6% in Russia, 3% in Poland, and 3% in Turkey. The remaining 14% of articles represent a series of single studies conducted in 11 countries. The revealed geographical imbalance between countries with developed production and the number of studies conducted in them shows a significant shortcoming in monitoring research. Most of the studies (20%) were devoted to the assessment of multicomponent emissions. A special place among them was occupied by the inventory of emissions using various methods. The next main directions in terms of the number of articles were aimed at studying the toxic metal emissions (19%), at the analysis of organic emissions (19%), at the modeling and forecasting of emissions (18%), and at particulate matter studies (15%). The main features of the articles for each direction are briefly noted. Citation analysis made it possible to compile a rating of articles of greatest scientific interest and the most authoritative journals. Citation network analysis revealed important insights into the structure of scientific communication in the monitoring of atmospheric pollution from the iron and steel industry. The results of our review will contribute to the consolidation of scientists, the identification of gaps in scientific knowledge, and the improvement of environmental policy and technological solutions. Full article
(This article belongs to the Section Air Pollution Control)
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