Search Results (190)

Introduction: Although lipomas are common benign tumors found in adults, lipomas of the bladder are extremely rare. Bladder lipomas are infrequently reported in the urologic literature, with only 19 cases published worldwide. These can present as a mass on cystoscopy and cause irritative voiding symptoms, depending on their location. Upon transurethral resection, seeing fat can be concerning for a perforation, as lipoma can be mistaken for extravesical fat. Hence, familiarity with this rare entity is of paramount importance for urologists to prevent unnecessary investigations and interventions that are needed in case of a true bladder perforation. Case presentation: This study presents a case of bladder lipoma in a 73-year-old male with end-stage renal disease who presented for pretransplant urologic evaluation due to microscopic hematuria and irritative lower urinary tract symptoms (LUTS). During cystoscopy, a bladder mass was seen, and a transurethral resection of the bladder tumor (TURBT) revealed bright yellow adipose tissue immediately underneath the bladder mucosa. Concerns about perforation were obviated when seeing intact detrusor muscle underneath, visually confirming the integrity of the bladder wall. The resection was completed, and the CT scan was re-read with the radiologist, which confirmed the presence of a lipoma that was missed pre-operatively due to patient’s oliguria and collapsed bladder. No catheter drainage or cystogram was performed based on these findings. Outcome: The patient healed without any complications. Histopathology confirmed the diagnosis of a mature lipoma. The patient was cleared for transplant from a urologic standpoint and had a successful renal transplantation without delay. Discussion: This case documents the anomalous occurrence of a lipoma within the bladder and supports maintaining a broad differential, including liposarcoma, angiomyolipoma, and other non-malignant fatty tumors during the evaluation of a bladder mass. Full article

The present study aimed to investigate the electrophysiological correlates of face-identity recognition in newborn infants immediately after birth. Electroencephalographic acquisition was continuously recorded in 23 newborn infants (3 < age < 24 h of life) during the following visual task: presentation of a woman’s face for 60 s (“known face”); random presentation of 50 known faces, 50 novel women’s faces, and 50 chessboards (for 2 s each). The final sample included in ERP analyses was composed of 11 newborn infants (male/female: 6/5; age: 5 h 16′ ± 3 h 51′). A greater negative amplitude of the N290 and smaller P400 and LC2 were found in response to the known face compared with the novel one in the left hemisphere. A shorter N290 latency was detected during the known face presentation compared with the novel one, and a longer latency of the same component was observed during novel face presentation compared with the chessboard. These findings suggest that newborns process a face differently from an object at birth and that they can discriminate a new face from a familiar one previously viewed for one minute. Full article

Vinegar functions not only as a sensory enhancer but also as a culturally embedded culinary element across global food systems. In Taiwanese cuisine, black vinegar represents a traditional staple, particularly associated with dumpling consumption, whereas Italian balsamic vinegar is renowned for its aromatic complexity and nuanced sweetness, highly esteemed in Western gastronomy. Despite their culinary significance, limited empirical research has examined how these culturally distinct condiments are perceived when applied beyond their traditional contexts, especially in iconic national dishes. This study investigates Taiwanese consumers’ cross-cultural sensory responses to dumplings paired with either local black vinegar or imported balsamic vinegar. Through a structured sensory evaluation encompassing appearance, aroma, taste, and overall impression, this research explores how sensory cues and cultural expectations interact to shape flavor preferences. The results indicate that although visual attributes were rated similarly, balsamic vinegar’s distinctive aroma and taste elicited significantly greater sensory engagement, suggesting a latent openness to reinterpretation and hybridization within established food practices. These findings were supported by one-way ANOVA results, which revealed significant differences among the three groups for aroma (F = 6.30, p < 0.01), taste (F = 7.21, p < 0.01), and overall evaluation (F = 15.15, p < 0.001). By integrating sensory analysis with cultural food studies, this research advances the understanding of how multisensory cues influence consumer acceptance across cultural contexts. It further highlights the dynamic interplay between cultural familiarity and sensory novelty in flavor perception. These insights yield practical implications for culinary innovation, global flavor localization, and the development of culturally responsive food products. Full article

Guide dogs are essential in supporting the autonomy of blind and visually impaired individuals. Austria is the first country to implement a legally mandated, two-stage certification protocol for the official recognition of guide dogs, assessed by an independent authority. The first stage includes two evaluation phases: the dog guides its familiar trainer (Phase 1) and then an unfamiliar blind tester (Phase 2). While Phase 2 ensures an objective assessment of guiding performance, it may also introduce stress due to the unfamiliar handler and separation from the trainer that could impact welfare and behaviour. This study aimed to evaluate whether Phase 2 of the Austrian evaluation protocol elicits higher stress than Phase 1 in guide dogs and, hence, needs to be refined in this regard by comparing physiological and behavioural responses between the two test phases. Fourteen guide dogs were assessed during real evaluations. Salivary cortisol was collected before the evaluation day and at several time points on the evaluation day (before and after each phase). Behavioural responses were coded from video recordings of the first 5 and 15 min of each phase, including stress-related behaviours, task-related performance behaviours, and handler behaviours. Cortisol levels did not differ significantly between the phases. Dogs turned around significantly more often in Phase 2, potentially seeking reassurance, but showed a non-significant trend toward fewer stress-related behaviours. Verbal praise occurred more frequently with the unfamiliar tester. These findings suggest that the current evaluation protocol does not induce substantial physiological or behavioural stress when dogs are guided by an unfamiliar tester, supporting its continued use as a welfare-conscious and objective certification approach that could also potentially serve as a model for other countries. Full article

Color blindness can create challenges in recognizing visual cues, potentially affecting players’ performance, emotional involvement, and overall gaming experience. This study examines the impact of color blindness on player engagement and emotional experiences in digital games. The research aims to analyze how color-blind individuals engage with and emotionally respond to games, offering insights into more inclusive and accessible game design. An experiment-based study was conducted using a between-group design with a total of 13 participants, including 5 color-blind and 8 non-color-blind participants (aged 18–30). The sample was carefully selected to ensure participants had similar levels of digital gaming experience and familiarity with digital games, reducing potential biases related to skill or prior exposure. A custom-designed game, “Color Quest,” was developed to assess engagement and emotional responses. Emotional responses were measured through Emotion AI analysis, video recordings, and self-reported feedback forms. Participants were also asked to rate their engagement and emotional experience on a 1 to 5 scale, with additional qualitative feedback collected for deeper insights. The results indicate that color-blind players generally reported lower engagement levels compared to non-color-blind players. Although quantitative data did not reveal a direct correlation between color blindness and visual experience, self-reported feedback suggests that color-related design choices negatively impact emotional involvement and player immersion. Furthermore, in the survey responses from participants, color-blind individuals rated their experiences lower compared to individuals with normal vision. Participants emphasized that certain visual elements created difficulties in gameplay, and alternative sensory cues, such as audio feedback, helped mitigate these challenges. This study presents an experimental evaluation of color blindness in gaming, emphasizing how sensory adaptation strategies can support player engagement and emotional experience. This study contributes to game accessibility research by highlighting the importance of perceptual diversity and inclusive sensory design in enhancing player engagement for color-blind individuals. Full article

Book covers are often the first component seen before a reader engages with a book’s contents; therefore, careful consideration is given to the text and image features that constitute their design. This study investigates the effects of the presentation of verbal (text) and visual (image) features on memorability and aesthetic evaluation in the context of book covers. To this aim, 50 participants took part in a memory recognition task in which the same book cover information was encoded in a learning phase, and either text or image features from the book covers acted as an informational cue for memory recognition and aesthetic evaluations. Our results revealed that image features significantly aided memory performance more than text features. Image features that were rated more beautiful were not better recognized as a result. However, differences in memory performance were found in relation to familiarity and, in a non-linear fashion, the extent to which the book’s contents could be inferred from the image’s informational content. Additionally, reading behavior was not found to influence memory performance. These results are discussed with regard to the interplay of text and image informational cues on book cover perception and provide implications for future studies. Full article

Rural agricultural markets face unique challenges, yet neuromarketing applications in this sector are understudied. This systematic review investigates how neuroscience has been applied to shape marketing narratives for rural agricultural producers. The objectives were to catalog relevant studies, identify key themes using inductive thematic synthesis, and derive practical implications for rural marketing strategy and future research. We systematically searched English-language, peer-reviewed studies published between 2016 and 2024 across multiple academic databases, following PRISMA guidelines. Two independent reviewers screened the records, resulting in the inclusion of 20 studies. Key data from each study were extracted and synthesized using an inductive thematic analysis approach. The synthesis revealed several recurrent findings. First, in terms of social and community context, farmers showed greater trust and engagement with familiar local buyers than with distant corporations, indicating that local relationships strongly influence producer behavior. Second, regarding product and narrative attributes, marketing narratives that emphasized local provenance, organic or sustainable production, and ethical values such as animal welfare and environmental sustainability resonated strongly with rural consumers. Third, sensory and emotional cues particularly visual elements and storytelling techniques including color, imagery, and packaging design consistently enhanced consumer attention and engagement. Overall, these neuroscience-informed themes suggest that marketing narratives emphasizing authenticity, trust-building, and community values can effectively strengthen rural agricultural marketing. This review provides neuroscience-informed interpretations of key rural marketing challenges, drawing on dual-process theory and consumer decision models for applying neuromarketing insights in this context. Practically, rural producers can leverage these findings by designing marketing messages and packaging that highlight local identity and ethical values, thereby building consumer trust and loyalty. The review also highlights gaps such as the need for more field-based neuromarketing studies and suggests directions for future research, offering guidance for both scholars and practitioners working at the intersection of neuroscience and rural consumer behavior. Full article

Introduction: The COVID-19 pandemic highlighted the need for digital tools that support public health decision-making and behavior change. Dashboards became a primary method for communicating infectious disease data. However, their influence on preventive health behaviors (PHBs) is not well understood—especially among young adults. This group is less likely to adhere to PHBs, but highly familiar with online tools. Methods: Two experimental studies were conducted with young adult participants (200 in Study 1, 228 in Study 2) who viewed the same COVID-19 data in dashboards with or without actionable components. Participants were randomly assigned to different dashboard conditions to measure, on seven-point Likert scales, their PHB intentions and perceptions of behavioral control, attitudes, norms, and risk. The actionable dashboard interventions, designed using the theory of planned behavior, included dynamic behavioral guidance and risk level visualizations. Results: Actionable dashboards versus basic dashboards significantly increased PHB intentions (B = 0.84, p < 0.001, Study 1). Dynamic behavioral guidance was the key dashboard component influencing PHB intentions (B = 0.61, p = 0.005, Study 2). Parallel mediation analysis testing norms, attitudes, behavioral control, and perceived risk against one another found that only norms explained the link between the dashboard intervention and PHB intentions (B_boot = 0.18 and 0.19). Conclusions: Findings suggest that actionable dashboards can effectively promote PHB by influencing psychosocial beliefs. These dashboards provide context and guidance, making risky situations more manageable and directing individuals to appropriate preventive actions. Public health professionals should consider incorporating behavioral guidance into community health dashboards to improve their effectiveness. Full article

Music has been shown to increase arousal and attention and even facilitate processing during non-musical tasks, including those related to speech and language functions. Mind wandering has been studied in many sustained attention tasks. Here, we investigated the intersection of these two phenomena: the role of mind wandering while listening to familiar/unfamiliar musical excerpts, and its effects on concurrent linguistic processing. We hypothesized that familiar music would be less distracting than unfamiliar music, causing less mind wandering, and consequently benefit concurrent speech perception. Participants (N = 96 young adults) performed a lexical-semantic congruity task where they judged the relatedness of visually presented word pairs while listening to non-vocal classical music (familiar or unfamiliar orchestral pieces), or a non-music environmental sound clip (control) played in the background. Mind wandering episodes were probed intermittently during the task by explicitly asking listeners if their mind was wandering in that moment. The primary outcome was accuracy and reactions times measured during the lexical-semantic judgment task across the three background music conditions (familiar, unfamiliar, and control). We found that listening to familiar music, relative to unfamiliar music or environmental noise, was associated with faster lexical-semantic decisions and a lower incidence of mind wandering. Mind wandering frequency was similar when performing the task when listening to familiar music and control environmental sounds. We infer that familiar music increases task enjoyment, reduces mind wandering, and promotes more rapid lexical access during concurrent lexical processing, by modulating task-related attentional resources. The implications of using music as an aid during academic study and cognitive tasks are discussed. Full article

Background: One-step cranioplasty combined with tumor removal is a recognized approach in neuro-oncology for patients with neoplastic skull invasion. The use of advanced technologies, including Mixed Reality (MR), has introduced new possibilities in surgical workflows. MR technology may provide additional benefits in preoperative planning, patient engagement, and intraoperative guidance. Can the proposed treatment algorithm, which includes Mixed Reality (MR) for preoperative planning and intraoperative navigation, demonstrate tangible utility and improve outcomes in the surgical management of skull-invasive tumors? Methods: A retrospective study was conducted on 14 patients treated at Cannizzaro Hospital, Catania, Italy, for skull-invasive tumors. The treatment algorithm incorporated tumor removal and one-step cranioplasty using custom-made titanium alloy meshes. Standard intraoperative navigation was compared with MR-based navigation. MR headsets and the Virtual Surgery Intelligence (VSI) platform were employed for preoperative planning, surgical guidance, and patient/family communication. Tumor types included nine meningiomas and five other tumor variants. Results: The integration of MR proved beneficial for preoperative planning, facilitating enhanced visualization of patient anatomy and aiding communication with patients and families. MR-assisted intraoperative navigation offered improved anatomical familiarity but demonstrated slightly lower accuracy compared with standard navigation. Postoperative outcomes were satisfactory across the cohort, with no significant complications reported. Conclusions: The study highlights the potential utility of the proposed treatment algorithm including MR technology in the surgical management of skull-invasive tumors. While MR provides enhanced visualization and preoperative engagement, standard navigation remains more precise during surgery. Nevertheless, MR serves as a valuable complementary tool, and its role in neuro-oncological workflows is expected to grow with technological advancements. Full article

This study focuses on the visual attention of residents and tourists to elements of urban landscapes from above. It screens out elements that attract viewers’ attention, assesses their aesthetics, and explores how these aesthetic evaluations affect the psychology of place identity. We tracked data from 30 participants, collected responses from 237 participants, and observed differences in visual behaviors and emotional connections to place identity. The results show that while residents and tourists exhibit similar visual behaviors when viewing the same landscape, they have large differences in their perceptual behaviors for different visual elements and have very different familiarity levels in the place identity dimension. Landmark buildings attract strong visual attention despite their low proportion in the overall landscape. Aesthetic factors such as the color vividness of elements like water, mountains, and landmark buildings significantly affect place identity. This study shows that combining eye-tracking and psychometric analysis can effectively evaluate urban landscape perception and provide valuable insights for visual planning and preservation efforts in historic neighborhoods. Full article

Prompt tuning visual-language models (VLMs) for specialized tasks often involves leveraging task-specific textual tokens, which can tailor the pre-existing, broad capabilities of a VLM to more narrowly focused applications. This approach, exemplified by CoOp-based methods, integrates mutable textual tokens with categorical tokens to foster nuanced textual comprehension. Nonetheless, such specialized textual insights often fail to generalize beyond the scope of familiar categories, as they tend to overshadow the versatile, general textual knowledge intrinsic to the model’s wide-ranging applicability. Addressing this base-novel dilemma, we propose the innovative concept of SparseKnowledge-guided Context Optimization (Sparse-KgCoOp). This technique aims to fortify the adaptable prompts’ capacity to generalize to categories yet unencountered. The cornerstone of Sparse-KgCoOp is based on the premise that reducing the differences between adaptive prompt and their hand-crafted counterparts through sparsification operations can mitigate the erosion of fundamental knowledge. Specifically, Sparse-KgCoOp seeks to narrow the gap between the textual embeddings produced by both the dynamic prompts and the manually devised ones, thus preserving the foundational knowledge while maintaining adaptability. Extensive experiments of several benchmarks demonstrate that the proposed Sparse-KgCoOp is an efficient method for prompt tuning. Full article

Lexical retrieval difficulty is a common daily complaint among older adults. Recent evidence suggests that older adults name motor-related nouns (e.g., knife) more accurately than non-motor nouns (e.g., steak). However, it remains unclear whether this motor-relatedness effect can reduce older adults’ object naming latency (a potentially more sensitive measure of word retrieval than accuracy) and how it may be modulated by individual differences (e.g., age and global cognition). Therefore, we recruited a large number of older adults to complete a Chinese version of the Montreal Cognitive Assessment (MoCA) and a timed picture-naming task, and we explored the two remaining issues with data from 76 community-dwelling older adults (65–81 years old), excluding participants with possible AD. Linear mixed-effects analysis revealed a main effect of motor-relatedness on naming latency in older adults and a significant interaction with the MoCA score after controlling for a number of stimulus-related factors (i.e., age of acquisition, familiarity, name agreement, and visual complexity) and participant-related factors (i.e., gender and education) as covariates, but age showed neither a main effect nor a significant interaction with motor-relatedness. Further simple slope analysis showed that older adults were faster at naming objects with high motor-relatedness and that older adults with low MoCA scores benefited more from the motor-relatedness effect. These findings suggest that motor-relatedness may compensate for the normal course of cognitive ageing in older adults. Implications for the motor-relatedness effect were discussed. Full article

The present study seeks to improve the accuracy and reliability of disease identification in apple fruits and leaves through the use of state-of-the-art deep learning techniques. The research investigates several state-of-the-art architectures, such as Xception, InceptionV3, InceptionResNetV2, EfficientNetV2M, MobileNetV3Large, ResNet152V2, DenseNet201, and NASNetLarge. Among the models evaluated, ResNet152V2 performed best in the classification of apple fruit diseases, with a rate of 92%, whereas Xception proved most effective in the classification of apple leaf diseases, with 99% accuracy. The models were able to correctly recognize familiar apple diseases like blotch, scab, rot, and other leaf infections, showing their applicability in agriculture diagnosis. An important by-product of this research is the creation of a web application, easily accessible using Gradio, to conduct real-time disease detection through the upload of apple fruit and leaf images by users. The app gives predicted disease labels along with confidence values and elaborate information on symptoms and management. The system also includes a visualization tool for the inner workings of the neural network, thereby enabling higher transparency and trust in the diagnostic process. Future research will aim to widen the scope of the system to other crop species, with larger disease databases, and to improve explainability further to facilitate real-world agricultural application. Full article

Thyroid-associated ophthalmopathy (TAO) is a vision-threatening autoimmune disease that involves the extraocular muscles (EOMs) and periorbital fat. Typical signs of TAO include eyelid recession, proptosis, diplopia, and decreased visual acuity. As a self-limited disease, there is major bipolarity in clinical outcomes in TAO population. The early diagnosis and prediction of these refractory and relapsed patients is essential. Unfortunately, commonly used tools such as CAS/NOSPECTS, are based on clinical symptoms and signs alone, have significant limitations. Some imaging techniques or examinations, such as magnetic resonance imaging (MRI), can be very effective in assisting TAO assessment, from exhaustive whiteboard notes to optimized patient outcomes. Being one of the most commonly used and accurate objective examinations for TAO assessment, MRI boosts no ionizing radiation, high soft tissue contrast, better reflection of tissue water content, and the ability to quantify multiple parameters. In addition, novel MR sequences are becoming increasingly more familiar in TAO and other areas of clinical and scientific research. Moreover, radiomics, a method involving the extraction of a large number of features from medical images through algorithms, is a more recent approach used in the analysis and characterization of TAO data. Thus, this review aims to summarize and compare the value of routine and novel functional MRI sequences and radiomics prediction models in the diagnosis and evaluation of TAO. Full article