Search Results (11,564)

To promote circular economy in construction, this study evaluates the mechanical surface integrity and long-term water durability of sustainable low-density particleboards utilizing agro-forestry residues, such as corn cob, corn stalk, hemp shive and wood fibres. These are bonded using an ecological mimosa tannin adhesive in comparison to a conventional urea–formaldehyde-based adhesive. Performance was assessed through apparent density, surface cohesion, Shore A hardness and impact resistance. Furthermore, the water sensitivity was assessed through total water absorption (WA), thickness swelling (TS), and a customized cyclic immersion-drying protocol. Results showed a significant correlation between density and Shore A hardness (R² = 0.77). While hemp- and corn-based boards showed surface performance competitive with commercial standards, the wood fibre series exhibited extreme water susceptibility, with mass variations exceeding 400% during cycling. Additionally, tannin-based boards showed evidence of leaching, with an 11% mass loss after three emersion cycles. These findings conclude that while tannin adhesives are viable renewable alternatives, these bio-boards are primarily suited for interior lining in dry environments, as lightweight formulations require additional protection to ensure durability in practical building applications. Full article

This study assessed the impact of pandemic-related changes in treated wastewater on surface water quality and ecological status of the Raba River within the Natura 2000 site. Particular attention to the reliability of the Kasinka Mała wastewater treatment plant operating in this protected area during the two study periods—pre-pandemic (PP) and COVID-19 (CP)—was given. For this purpose, current standard monitoring methods (ecological status of a small flysch stream, existing and potential threats to the Natura 2000 site) and extended monitoring methods (river’s utility values, technological reliability of the treatment plant operating with SBR technology, reliability rating of the river as a sewage receiver) were used. The results indicated that biodegradable carbon compounds (as dissolved and suspended forms) and ammonium nitrogen were the dominant factors determining water quality. Their presence reduced the Raba River’s utility value—determined by what is required of surface water treatment—by at least one class. During the CP, the reliability analysis showed that the river remained in a reduced class for 145 days due to elevated BOD₅ and nearly one-third of the year due to elevated TSS levels. For approximately half of the year, ammonium nitrogen concentrations exceeded the threshold of 1.8 mg·dm⁻³, thereby further reducing the class of water quality. Technological reliability of the WWTP during PP for BOD₅, COD, TSS, NH₄⁺–N, and PO₄⁻³–P was 43%, 100%, 30%, 86%, and 100%, respectively. This means that permitted values of COD and PO₄⁻³–P were maintained. The exceedances of limits concerned BOD₅ (25 mg O₂·dm⁻³ for 208 days), TSS (35 mg O₂·dm⁻³ for 256 days), and NH₄⁺–N (15 mg O₂·dm⁻³ for 51 days). During CP, the technological reliability of the WWTP decreased rapidly for the following pollutants to 5%, 18%, 18%, 30%, and 89%, respectively. This means that permissible concentrations of BOD₅ (25 mg O₂·dm⁻³ for 347 days), COD (125 mg O₂·dm⁻³ for 241 days), TSS (35 mg O₂·dm⁻³ for 299 days), NH₄⁺–N (15 mg O₂·dm⁻³ for 256 days), and PO₄⁻³–P (2 mg O₂·dm⁻³ for 40 days) were exceeded. A two-year monitoring campaign has shown that small flysch rivers receiving treated wastewater may experience prolonged changes in water quality under conditions of increased anthropopressure. Effective ecosystem protection should, therefore, include extended monitoring and stricter management of BOD₅, TSS, and NH₄⁺–N in SBR systems in protected areas. Full article

Against the backdrop of global climate change and the “carbon neutrality” target, the ecological quality improvement of the Loess Plateau—a key region for ecological restoration in China—and its impact on vegetation carbon sources hold significant importance for regional carbon balance and ecological security. Based on MODIS and meteorological reanalysis data from 2002 to 2024, this study constructed the Remote Sensing Ecological Index (RSEI). Combined with a carbon source/sink model, it systematically assessed the spatiotemporal coupling evolution characteristics of ecological environment quality and vegetation carbon storage capacity in the Loess Plateau, and explored the synergistic driving mechanisms of major hydrothermal and surface factors. The results indicate the following: (1) From 2002 to 2024, the ecological environment of the Loess Plateau improved significantly, with the RSEI rising from moderate to good. This improvement was accompanied by a marked decrease in surface dryness, an increase in surface wetness, and notable growth in vegetation cover, revealing a positive coupling relationship characterized by “reduced surface dryness—increased surface wetness—enhanced vegetation restoration.” (2) Regional vegetation carbon storage capacity strengthened markedly. Gross Primary Productivity (GPP), Net Primary Productivity (NPP), and Net Ecosystem Productivity (NEP) all showed significant increasing trends, and the proportion of area classified as carbon sink increased substantially. (3) Spatially, carbon sink distribution exhibited a pattern of “higher in the southeast, lower in the northwest.” Sub-regions A and D were identified as core areas with higher ecological quality and carbon sink capacity, whereas sub-regions B and C were more ecologically fragile and served as primary carbon source areas. (4) The implementation of soil and water conservation measures on the Loess Plateau has effectively enhanced regional carbon storage capacity. Vegetation restoration, improved water conditions, and reduced surface dryness have jointly driven the transition of the Loess Plateau ecosystem from a “vulnerable type” to a “recovering type”, while ecological restoration projects have played a certain role in enhancing the carbon sink. This study provides a theoretical basis and scientific–technological support for ecological protection and high-quality development in the Yellow River Basin. Full article

The management of red mud (bauxite residue, RM) is critical for environmental protection due to its high alkalinity (pH 12.5–13.0). The study investigates the valorization of RM from the ALUM Tulcea unit (Romania) through accelerated wet carbonation processes (L/S ratio 4:1) and its integration into sustainable construction materials (paving stones). The results indicate a reduction the pH to a stable level of 8.6 in 240 min, a process validated by the formation of new mineral phases (calcite and dawsonite) that stabilize the residual sodium. For the optimized recipe S2 (20% RM, 12% cement, 48% fly ash), an average compressive strength of 33.8 MPa (class T5 according to SR EN 1338:2004) and a low water absorption of 4.12% (Class B) were obtained. Durability tests confirmed superior freeze–thaw resistance (mass loss 0.58 kg/m²) and sodium (Na⁺) leaching below 2.1 mg/L, well below EU limits. In the case of alkaline activated geopolymers (NaOH 8 M), the strength reached 38.5 MPa. The study demonstrates that carbonated RM can reduce the carbon footprint by 20–56% and production costs by up to 43%, providing a viable circular economy solution in line with EU 2030 targets. Full article

Soft spread cheese is highly perishable, and conventional packaging offers limited protection against surface spoilage. Here, we present a sustainable, multifunctional solution: edible films made from whey protein concentrate (WPC), a valuable by-product of the cheese industry, incorporated with the probiotic Lactobacillus acidophilus LA5 (LA5). The objective of this study was to evaluate these films as active coatings for soft cheese, specifically assessing their physicochemical properties, probiotic viability during storage and simulated gastric transit, and their impact on cheese microbial stability and sensory quality over 60 days. Applied as active coatings on soft cheese stored at 4 °C for 60 days, these films were evaluated for their physicochemical properties, probiotic viability, microbial stability, and sensory acceptance. The incorporation of LA5 did not significantly alter film thickness (control: 0.20 ± 0.03 mm; test: 0.18 ± 0.02 mm), moisture content (control: 33.42 ± 0.54%; test: 32.34 ± 1.28%), or water solubility (control: 21.44 ± 1.14%; test: 22.89 ± 0.75%) (p > 0.05). However, mechanical properties were markedly modified: tensile strength decreased from 35.42 ± 5.38 MPa (control) to 6.04 ± 0.55 MPa (test), while elongation at break increased from 4.87 ± 0.93% to 68.23 ± 3.46% (p < 0.05), indicating a transition from rigidity to flexibility upon probiotic incorporation. The probiotic strain exhibited exceptional resilience, retaining 100% viability during simulated gastric exposure at both day 0 and day 30 of storage. During cheese storage, LA5 counts in test film-coated samples remained above the recommended therapeutic threshold (10⁶ cfu/g), starting at 7.44 ± 0.15 log(cfu/g) on day 0 and maintaining 6.56 ± 0.20 log(cfu/g) after 60 days. Critically, yeast and mold spoilage were delayed in probiotic-coated cheese, with detectable growth appearing only at day 60 (1.64 ± 1.34 log(cfu/g)), whereas uncoated cheese showed spoilage as early as day 28 (1.33 ± 1.62 log(cfu/g)). Sensory evaluation revealed no significant differences (p > 0.05) between the coated and uncoated samples for color, appearance, texture, flavor, or overall acceptability. By valorizing a dairy by-product into an active, probiotic-loaded edible film, this approach offers a sustainable, waste-reducing strategy that enhances cheese preservation while delivering added functional value—bridging the gap between food packaging and nutrition. Sensory evaluation (n = 8, preliminary) indicated no significant differences between coated and uncoated samples, but these results require confirmation with a larger, validated panel. Full article

The development of highly sensitive and reliable strategies for microcystin-LR (MC-LR) monitoring remains critical for environmental safety and public health protection. Herein, we report a metallene-enabled electrochemiluminescence (ECL) biosensing platform based on ultrathin PdMoCu trimetallic metallenes for femtogram-level MC-LR detection. The two-dimensional PdMoCu metallenes provide abundant active sites and accelerated interfacial charge-transfer kinetics through synergistic electronic modulation among Pd, Mo, and Cu atoms, significantly enhancing the Ru(bpy)₃²⁺/TPrA ECL efficiency. By integrating a programmable H1–aptamer duplex interface, electrostatic enrichment of Ru(bpy)₃²⁺ was achieved, enabling target-responsive luminophore release via aptamer-triggered structural switching. This cooperative amplification mechanism, combining catalytic acceleration and DNA-mediated signal modulation, results in a sensitive signal-off detection mode. Under optimized conditions, the biosensor exhibited a wide linear response from 0.1 pg mL⁻¹ to 50 ng mL⁻¹ with a detection limit as low as 37 fg mL⁻¹. The platform demonstrated excellent selectivity against structural analogues, high reproducibility, and satisfactory recovery (99.3–102.0%) in real tap water samples. This work not only highlights the catalytic potential of trimetallic metallenes in ECL systems but also establishes a generalizable interfacial engineering strategy for ultrasensitive detection of trace environmental contaminants. Full article

The extensive use of 2,4-dichlorophenoxyacetic acid (2,4-D) in agriculture has led to water contamination and associated health risks, highlighting the need for eco-friendly detection strategies. Herein, Fe₃O₄ nanoparticles were green-synthesized for the first time using an aqueous extract of Rumex nervosus (R. nervosus) as a natural reducing and stabilizing agent and successfully employed for the electrochemical sensing of 2,4-D, representing the first reported application of R. nervosus-mediated Fe₃O₄ nanoparticles for this purpose. The phytochemical composition of the extract and synthesized R-Fe₃O₄ nanoparticles were systematically characterized. The R-Fe₃O₄-modified glassy carbon electrode (GCE) was evaluated for charge transfer properties using electrochemical impedance spectroscopy (EIS). Cyclic voltammetry (CV) showed no redox peak for 2,4-D at the bare GCE, whereas R-Fe₃O₄/GCE exhibited a distinct reduction peak at ~−1.5 V in 0.1 M phosphate buffer (pH 7), attributed to reductive dechlorination. Square-wave voltammetry (SWV) exhibited a linear response over the concentration range of 50–325 µM with a detection limit of 3.35 µM for 2,4-D. Although this performance is slightly above the guideline limits recommended by the World Health Organization (~0.14 µM) and the United States Environmental Protection Agency (~0.32 µM), it is suitable for the routine monitoring of elevated 2,4-D levels in environmental samples. The sensor demonstrated high selectivity with negligible interference and satisfactory recoveries of 96.6–98.3% in real water samples. Full article

Valorization of abundant agricultural residues, particularly lignin, provides the opportunity to divert waste streams while enabling materials to inherently exhibit durable functionalities, including UV-blocking, antioxidant properties and water repellency. This study reports the side-by-side valorization of hemp hurd (HL) and corn stover lignin (CL), extracted using the CELF process, into electrospun lignin/nylon 6 nanofiber membranes, establishing how lignin botanical origin, molecular weight (M_w), and blend ratio govern multifunctional performance relevant to protective membranes in textiles. Lignin–nylon 6 hydrogen bonding was regulated by the OH content and accessibility, M_w, and purity, and influenced the functional properties of the fibers. While stronger in low-M_w nanofibers, these interactions were weakest in low-M_w HL samples due to the lowest purity, despite the highest OH content. Fibers with low-M_w lignin yielded finer, brittle fibers with higher UV blocking, whereas high-M_w fractions showed higher antioxidant performance due to decreased interactions with nylon 6. Overall, lignin/nylon 6 nanofiber membranes delivered biobased UPF 50+ performance, 55–61% antioxidant activity at the optimal concentration, and exhibited tunable water repellency via fraction selection and the blend ratio. In combination with a nanofiber architecture, these membranes can impart durable inherent functionality onto textile substrates without affecting their existing properties, including water vapor permeability, without the use of chemical finishing, while utilizing renewable resources from agricultural residues. Full article

The skin serves as a primary defensive barrier to protect the body from environmental contaminants, infections and trauma. Unfortunately, skin barrier’s structural and functional integrity can be compromised, disrupted or impaired due to a combination of internal and external factors, making it vulnerable and often leading to a wide range of skin conditions characterized by dryness, heightened sensitivity, and increased susceptibility to damage and infections. In addition, the integrity of the skin barrier tends to deteriorate progressively with age. As people age, their skin naturally changes and can also be compromised by a plethora of factors that reduce its strength and resilience. The aging skin becomes thinner and more sensitive, coinciding with a variety of structural–functional alterations, decreased levels of natural moisturizing factor (NMF), lipid content and hydration, increased transepidermal water loss (TEWL), altered skin surface pH (pHss) and microbiome diversity. All these age-related skin integrity alterations make the skin drier, flakier, itchy, and fragile, and more susceptible to damage and breakdown, thus diminishing its ability to effectively protect, repair and heal efficiently. Identifying skin integrity issues before they progress will foster positive outcomes through effective preventive measures. Hence, it is important to understand the impact of skincare formulations on skin integrity in compromised aging skin. A well-considered, evidence-based approach to skincare can provide cleansing, moisturizing and protective benefits, while aiding the reduction in skin integrity issues like dry and itchy skin, sensitive skin, bruising, skin tears, pressure injuries (PIs), lower leg ulcers and moisture-associated skin damage (MASD). Managing skin integrity in compromised aging skin begins with gentle skin cleansing, adequate moisturization and protective barrier care to ensure the skin’s function is maximized. Full article

Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening vascular disease lacking therapies that target underlying cell death pathways. Ferroptosis, an iron-dependent form of lipid peroxidation-driven cell death, has emerged as a key mechanism in vascular remodeling. We investigated whether exogenous ketosis induced by ketone ester (KE) supplementation can suppress ferroptosis and prevent TAAD. TAAD was induced in C57BL/6 mice using β-aminopropionitrile (BAPN). A subset of these mice received KE [(R)-3-hydroxybutyl (R)-3-hydroxybutyrate, 20 g/L] in their drinking water starting on day 15 of the BAPN treatment. Human aortic smooth muscle cells (HASMCs) were treated with the GPX4 inhibitor Ras-Selective Lethal 3 (RSL3) and β-hydroxybutyrate (β-OHB) to investigate ferroptotic markers, lipid peroxidation, and labile iron levels. KE supplementation significantly reduced TAAD incidence (69% → 43%) and improved survival rate (52% → 73%), while preserving aortic structure and reducing elastic fiber fragmentation. Transcriptomic analyses of human TAAD datasets (GSE153434 and GSE52093) and single-cell RNA sequencing data (GSE155468) revealed ferroptosis signatures characterized by decreased GPX4 and increased expression of iron metabolism genes. Mechanistically, KE suppressed BAPN-induced iron accumulation and lipid peroxidation in vivo. In HASMCs, β-OHB inhibited ferroptosis induced by GPX4 inhibition, decreasing lipid peroxidation and labile iron levels. KE restored GPX4 and SLC7A11 expression while suppressing HO-1 in vivo, with effects dependent on Nrf2 signaling in vitro. In summary, ketone ester supplementation protects against TAAD by inhibiting VSMC ferroptosis via GPX4 induction and HO-1 suppression, highlighting a potential therapeutic strategy for aortic disease. Full article

Coastal aquifers are essential freshwater sources for domestic, agricultural, and industrial use, particularly in regions where surface water is limited. However, these systems face growing stress from saltwater intrusion, climate-driven reductions in recharge, sea level rise, and intensified groundwater extraction. This review synthesizes recent research on coastal aquifer responses to these pressures, highlighting the interplay between natural hydrogeologic conditions and human-induced demand. Across deltaic and sedimentary systems, studies consistently show declining groundwater levels, the landward migration of saline interfaces, and reduced aquifer buffering capacity, especially in areas with high evaporation and limited recharge. The review also evaluates emerging strategies to preserve coastal groundwater security. Integrated hydrological models, managed aquifer recharge (MAR), optimized abstraction schemes, and remote sensing-based monitoring are advancing adaptive management capabilities. In parallel, policy and nature-based interventions—such as aquifer protection zoning, wetland rehabilitation, and dune system restoration—support long-term resilience by enhancing natural recharge and reducing vulnerability. The overall findings reveal the need for climate-informed and locally tailored groundwater management. Future efforts should prioritize coupling high-resolution climate projections with aquifer system models, evaluating MAR viability in saline-prone environments, and strengthening collaborative governance frameworks to ensure sustainable and equitable use of coastal aquifers. Full article

The impact of short-distance lateral shield tunneling threatens the safety of operational high-speed railways (HSRs). To address the engineering challenge of “how to select isolation pile density under fixed cost constraints,” this study focuses on the Xi’an Metro shield tunnel section passing laterally adjacent to the Daxi and Zhengxi Passenger Dedicated Lines. Under the constraint of identical total economic costs, two isolation pile schemes—low-density and high-density—were established to investigate the control patterns of different densities on HSR bridge piles and surrounding ground surface deformation. A three-dimensional (3D) numerical model was developed for the lateral shield tunneling process. Combined with field-measured data, numerical simulations were conducted for corresponding construction stages to analyze the disturbance effects of shield tunneling on HSR piers and the surrounding ground, as well as the deformation restraint performance of isolation piles. The results indicate that the high-density isolation pile scheme (pile spacing: 2.0 m; pile length: 22 m) provides superior control compared to the low-density scheme (pile spacing: 4 m; pile length: 28 m). Following single- and double-track excavation, the vertical displacement of HSR piers was reduced by 0.6 mm and 1.1 mm, respectively—a reduction of 40–74%. Furthermore, the pier displacement along the depth direction shifted from non-uniform to relatively uniform. The difference in surface settlement between the two schemes was only 0.2 mm, suggesting that isolation pile density has a marginal impact on ground deformation. The horizontal displacement of high-density isolation piles stabilized at 1.7–1.9 mm, with vertical heave ranging from 1.2 to 1.4 mm. The lateral displacement profile exhibited a regular “double-C outward expansion” shape, which is better suited to the characteristics of water-rich sand layers. Initial excavation causes significant disturbance to the original strata, necessitating enhanced stress field protection measures. The high-density scheme is recommended for engineering applications, as it achieves optimal control of bridge pile deformation under cost constraints and meets regulatory specifications. Full article

Sustainable valorization of biomass through hydrothermal carbonization (HTC) represents an environmentally benign method for producing carbon materials for water treatment applications. This research aims to optimize the production of hydrochar from waste food by focusing on parameter optimization, physicochemical characterization, and the capacity of hydrochar to act as an adsorbent for the removal of the copper (II) ion from polluted water. A design of experiments using the RSM approach was employed to evaluate and optimize the influence of carbonization temperature, ranging from 180 to 250 °C, with a residence time of 2–5 h. The predictive ability of the MINITAB-generated model was close to accurate, as demonstrated by the design application for process simulation. The maximum % hydrochar yield was 72.65% for the experimental yield and 71.53% for the predicted yield, both obtained from a sample carbonized at 166 °C for 3.5 h. Batch adsorption experiments were conducted to assess the hydrochar’s ability to remove Cu²⁺ from aqueous solutions, and the Langmuir and the Freundlich isotherms were fitted at different pH levels. A comprehensive characterization of the produced hydrochar was conducted using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), X-ray fluorescence (XRF), and scanning electron microscopy (SEM-EDS). The results revealed significant modifications in surface morphology, pore development, and the presence of oxygen-containing functional groups. Based on the findings in this report, it is safe to conclude that hydrochar derived from food waste could serve as a potential adsorbent. Overall, the study demonstrates that sustainable hydrochar production from biomass can simultaneously address waste management challenges and provide an efficient solution for heavy metal removal, thereby advancing circular bioeconomy and environmental protection. Full article

Although microbial biopesticides are expanding rapidly, transforming nematophagous fungi into consistent and shelf-stable products remains a challenge. A key limitation is that fungal propagules must remain viable throughout production, storage, and delivery to ensure their efficacy in the field. This review examines formulation strategies that improve the stability, deployment, and performance of fungal biocontrol agents against gastrointestinal helminths in domestic animals and plant-parasitic nematodes. In veterinary systems, predatory fungi such as Duddingtonia flagrans primarily target infective larvae after surviving gastrointestinal transit and germination in feces. In contrast, ovicidal fungi, including Pochonia chlamydosporia, Purpureocillium lilacinum, Trichoderma spp., and Mucor spp., primarily act against helminth eggs and coccidian oocysts. This functional complementarity highlights the potential of combined fungal formulations to improve their control efficacy. We also discuss the currently available D. flagrans-based commercial products, BioWorma^® and Bioverm^®, and the practical challenges associated with dosing, administration, and farm adoption. In agriculture, we show that the Brazilian market is dominated by solid fungal nematicides designed to reduce water activity and prolong shelf life, although liquid- and oil-based systems remain relevant for specific applications. Across both sectors, the review identified formulation design, rather than fungal species alone, as a critical determinant of product performance. Emerging advances, such as microencapsulation, UV-protective matrices, improved seed-coating biopolymers, nanobiotechnology, and fungal-derived bioactive products, indicate that future progress will depend on target-oriented formulations capable of increasing stability, controlled release, and resilience under environmentally variable conditions, including those imposed by climate change. Full article

Background/Objectives: Camellia bee pollen refers to pollen pellets collected by bees from plant stamens and mixed with salivary secretions. Alcoholic fatty liver disease (AFLD), as the initial phase within the spectrum of alcohol-induced liver diseases, has resulted in a rising global incidence rate and treatment burden of such liver ailments. Methods: This study employs acute zebrafish juvenile and adult zebrafish chronic alcoholic liver models to explore the protective effects of camellia bee pollen as well as its ethanol and water extracts on zebrafish alcoholic fatty liver. Results: The research findings indicate that the intervention group treated with camellia bee pollen significantly mitigated the accumulation of lipid droplets in zebrafish larvae and notably improved the liver lobule structure of adult zebrafish, bringing it close to normal conditions. The camellia pollen intervention group could significantly decrease the levels of triglyceride (TG), total cholesterol (T-CHO), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and malondialdehyde (MDA), while increasing the levels of glutathione (GSH) and total superoxide dismutase (T-SOD). Conclusions: This experiment indicates that the pollen of tea flowers has a significant protective effect against alcoholic liver damage. Full article