Advances in Tissue Engineering Approaches for Bone Repair and Regeneration
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 10 July 2026 | Viewed by 1280
Special Issue Editor
Interests: osteogenic differentiation; dental pulp; dental cells; drug delivery and tissue engineering; organoid; scaffold-free stem cells
Special Issue Information
Dear Colleagues,
Bone tissue engineering has emerged as a promising strategy for the repair and regeneration of critical-size bone defects caused by trauma, degenerative diseases, congenital abnormalities, and tumor resection. In parallel, cancer-related bone diseases—such as primary bone tumors and bone metastases—pose significant clinical challenges due to complex tumor–bone interactions, impaired healing, and high recurrence rates.
Recent advances in tissue engineering have expanded beyond conventional regenerative approaches to include cancer-related applications, such as engineered bone tumor models, biomimetic platforms for studying tumor microenvironments, and multifunctional scaffolds capable of promoting bone regeneration while delivering anti-cancer therapies. The integration of biomaterials, stem cells, growth factors, and advanced fabrication technologies (e.g., 3D printing and bioprinting) has opened new avenues for both bone repair and cancer research.
This Special Issue, “Advances in Tissue Engineering Approaches for Bone Repair and Regeneration,” aims to gather high-quality contributions addressing fundamental, translational, and clinical aspects of bone tissue engineering in both regenerative and oncological contexts.
We invite original research articles, reviews, and short communications focusing on, but not limited to, the following topics:
- Biomaterials and scaffolds for bone repair after tumor resection;
- Tissue-engineered models of bone cancer and bone metastasis;
- Tumor microenvironment and cancer–bone interactions;
- Multifunctional scaffolds for combined bone regeneration and anti-cancer therapy;
- Stem cell-based strategies in bone regeneration and cancer research;
- Three-dimensional printing and bioprinting for bone repair and tumor modeling;
- Drug delivery systems targeting bone tumors;
- In vitro and in vivo models for bone regeneration and cancer;
- Clinical translation in orthopedic oncology and regenerative medicine.
We believe that this Special Issue will serve as a valuable platform for researchers working at the interface of tissue engineering, bone biology, and cancer research.
Dr. Elaheh Dalir Abdolahinia
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bone tissue engineering
- bone regeneration
- biomaterials and scaffolds
- bone cancer
- 3D printing
- bioprinting
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