Advances in Counter-Current Chromatography

Dear Colleagues,

Counter-current chromatography (CCC) is a unique type of liquid–liquid partition chromatography. As it does not utilize solids as a support matrix, CCC is not beset by the many complications that arise from using solid-supporting materials, such as irreversible absorption, constituent losses and deactivation, the tailing of solute peaks and contamination. Compared to other forms of chromatography that feature solid-supporting materials, including silica column chromatography and reversed-phase liquid chromatography, CCC offers more advantages such as a high retention of the stationary phase, better selection, and more solvent-saving abilities. Therefore, CCC have been widely employed for the separation and preparation of natural and synthetic compounds from complex mixtures in many fields.

In this Topic, we will focus on the separation and purification of bioactive natural products via CCC or CCC-related separation techniques. Discussions pertaining to the development of novel CCC instruments and separation methods are encouraged and general reviews and experimental reports are welcome.

Dr. Shihua Wu
Dr. Xinyi Huang
Dr. Zhi Yang
Topic Editors