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Molecules 2012, 17(11), 13368-13375; doi:10.3390/molecules171113368

One-Pot Synthesis of 2-Phenylimidazo[1,2-α]pyridines from Acetophenone, [Bmim]Br3 and 2-Aminopyridine under Solvent-Free Conditions

Department of Applied Chemistry, East China Institute of Technology, Fuzhou 344000, China
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Author to whom correspondence should be addressed.
Received: 24 September 2012 / Revised: 24 October 2012 / Accepted: 26 October 2012 / Published: 9 November 2012
(This article belongs to the Section Organic Synthesis)
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Abstract

One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br3 and 2-aminopyridine under solvent-free conditions in the presence of Na2CO3, gave the corresponding 2-phenylimidazo[1,2-α]pyridines in excellent yields ranging from 72% to 89%.
Keywords: imidazo[1,2-α]pyridine; aromatics; 2-aminopyridine; [Bmim]Br3 imidazo[1,2-α]pyridine; aromatics; 2-aminopyridine; [Bmim]Br3
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Le, Z.-G.; Xie, Z.-B.; Xu, J.-P. One-Pot Synthesis of 2-Phenylimidazo[1,2-α]pyridines from Acetophenone, [Bmim]Br3 and 2-Aminopyridine under Solvent-Free Conditions. Molecules 2012, 17, 13368-13375.

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