Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis
Abstract
:1. Introduction
2. Results and Discussion
Position | δΗ (J in Hz) | δC, Mult. | 1H–1H COSY | HMBC (H→C) |
---|---|---|---|---|
1 | 177.2, C | |||
2 | 2.48 m | 39.4, CH | H2-3, H3-9 | C-1, -3, -4, -9 |
3 | 1.67 m; 1.40 m | 34.2, CH2 | H-2, H2-4 | C-1, -2, -4, -5, -9 |
4 | 1.45 m; 1.38 m | 21.6, CH2 | H2-3, H2-5 | C-2, -3, -5, -6 |
5 | 1.74–1.39 m | 41.7, CH2 | H2-4 | C-3, -4, -6, -7, -10 |
6 | 72.5, C | |||
7 | 1.74–1.39 m | 40.2, CH2 | H2-8 | C-5, -6, -8, -10, -1' |
8 | 2.53 m | 21.3, CH2 | H2-7 | C-6, -7, -1', -2', -6' |
9 | 1.17 d (7.2) | 17.1, CH3 | H-2 | C-1, -2, -3 |
10 | 1.22 s | 26.6, CH3 | C-5, -6, -7 | |
1' | 144.3, C | |||
2' | 140.2, C | |||
3' | 187.6, C | |||
4' | 140.4, C a | |||
5' | 140.6, C a | |||
6' | 187.2, C | |||
7' | 2.03 s | 12.0, CH3 | C-1', -2', -3' | |
8' | 2.01 s | 12.3, CH3b | C-3', -4', -5' | |
9' | 2.01 s | 12.4, CH3b | C-4', -5', -6' | |
1-OCH3 | 3.68 s | 51.5, CH3 | C-1 |
3. Experimental
3.1. General
3.2. Animal Material
3.3. Extraction and Isolation
3.4. In Vitro Anti-Inflammatory Assay
4. Conclusions
Acknowledgments
Conflicts of Interest
References and Notes
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- Sample Availability: Not available.
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Lin, Y.-F.; Kuo, C.-Y.; Wen, Z.-H.; Lin, Y.-Y.; Wang, W.-H.; Su, J.-H.; Sheu, J.-H.; Sung, P.-J. Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis. Molecules 2013, 18, 8160-8167. https://doi.org/10.3390/molecules18078160
Lin Y-F, Kuo C-Y, Wen Z-H, Lin Y-Y, Wang W-H, Su J-H, Sheu J-H, Sung P-J. Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis. Molecules. 2013; 18(7):8160-8167. https://doi.org/10.3390/molecules18078160
Chicago/Turabian StyleLin, Yu-Fang, Chao-Ying Kuo, Zhi-Hong Wen, Yen-You Lin, Wei-Hsien Wang, Jui-Hsin Su, Jyh-Horng Sheu, and Ping-Jyun Sung. 2013. "Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis" Molecules 18, no. 7: 8160-8167. https://doi.org/10.3390/molecules18078160