Previous Issue

E-Mail Alert

Add your e-mail address to receive forthcoming issues of this journal:

Journal Browser

Journal Browser

Table of Contents

Molecules, Volume 7, Issue 12 (December 2002), Pages 854-921

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
View options order results:
result details:
Displaying articles 1-11
Export citation of selected articles as:

Editorial

Jump to: Research, Other

Open AccessEditorial A New Editorial Office in Qingdao, a New E-Publishing System for MDPI Journals and Beilstein Starts Coverage of Molecules
Molecules 2002, 7(12), 855-857; doi:10.3390/71200855
Published: 31 December 2002
Cited by 2 | PDF Full-text (16 KB) | HTML Full-text | XML Full-text
Open AccessEditorial New Development: A Printed Edition
Molecules 2002, 7(12), 858-860; doi:10.3390/71200858
Published: 31 December 2002
Cited by 3 | PDF Full-text (245 KB) | HTML Full-text | XML Full-text

Research

Jump to: Editorial, Other

Open AccessArticle Electrochemical Anion Recognition By Novel Ferrocenyl Imidazole Systems
Molecules 2002, 7(12), 861-866; doi:10.3390/71200861
Received: 22 November 2002 / Revised: 3 December 2002 / Accepted: 4 December 2002 / Published: 31 December 2002
Cited by 22 | PDF Full-text (39 KB) | HTML Full-text | XML Full-text
Abstract
A novel class of anion receptors with with C-H···X- hydrogen bonding is introduced and demonstrated for Cl-, Br-, NO3- and HSO4- recognition. Cyclic voltammetry revealed that novel ferrocenylimidazolium salts, syntheses of which are briefly
[...] Read more.
A novel class of anion receptors with with C-H···X- hydrogen bonding is introduced and demonstrated for Cl-, Br-, NO3- and HSO4- recognition. Cyclic voltammetry revealed that novel ferrocenylimidazolium salts, syntheses of which are briefly described, selectively complex and electrochemically recognise guest anions. Futhermore, proton NMR spectroscopy indicated the formation of 1:2 stoichiometric complexes with Cl-, Br and I- and 1:1 stoichiometric complexes with NO3- and HSO4-. Full article
Open AccessArticle Microwave-Accelerated Iodination of Some Aromatic Amines, Using Urea-Hydrogen Peroxide Addition Compound (UHP) as the Oxidant
Molecules 2002, 7(12), 867-870; doi:10.3390/71200867
Received: 15 October 2002 / Revised: 11 December 2002 / Accepted: 12 December 2002 / Published: 31 December 2002
Cited by 10 | PDF Full-text (22 KB) | HTML Full-text | XML Full-text
Abstract
A fast and simple method for the oxidative iodination of some aromatic amines, under microwave irradiation, is reported, using diiodine and the the strongly Hbonded urea-hydrogen peroxide addition compound (H2NCONH2···H2O2, UHP) as the oxidant.
[...] Read more.
A fast and simple method for the oxidative iodination of some aromatic amines, under microwave irradiation, is reported, using diiodine and the the strongly Hbonded urea-hydrogen peroxide addition compound (H2NCONH2···H2O2, UHP) as the oxidant. The reactions were carried out in boiling CHCl3 under a reflux condenser to afford, within 10 minutes, the purified monoiodinated products in 40-80% yields. Full article
Open AccessArticle Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series
Molecules 2002, 7(12), 871-884; doi:10.3390/71200871
Received: 13 August 2002 / Revised: 28 November 2002 / Accepted: 4 December 2002 / Published: 31 December 2002
Cited by 3 | PDF Full-text (143 KB) | HTML Full-text | XML Full-text
Abstract Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(pfluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoroanilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b]furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders. Full article
Open AccessArticle Synthesis and Characterization of New 3,5-Dinaphthyl Substituted 2-Pyrazolines and Study of Their Antimicrobial Activity
Molecules 2002, 7(12), 885-895; doi:10.3390/71200885
Received: 12 March 2002 / Revised: 15 November 2002 / Accepted: 17 November 2002 / Published: 31 December 2002
Cited by 71 | PDF Full-text (397 KB) | HTML Full-text | XML Full-text | Correction | Supplementary Files
Abstract
A number of chalcones were prepared by condensing either 1-acetylnaphthalene or substituted 1-acetylnaphthalenes with 1-naphthaldehyde or 4-dimethylamino-1-naphthaldehyde in ethanolic NaOH solutions. These chalcones were immediately reacted with hydrazine hydrochloride, phenyl hydrazine and semicarbazide hydrochloride in the presence of dry acetic acid to obtain
[...] Read more.
A number of chalcones were prepared by condensing either 1-acetylnaphthalene or substituted 1-acetylnaphthalenes with 1-naphthaldehyde or 4-dimethylamino-1-naphthaldehyde in ethanolic NaOH solutions. These chalcones were immediately reacted with hydrazine hydrochloride, phenyl hydrazine and semicarbazide hydrochloride in the presence of dry acetic acid to obtain the corresponding 2-pyrazolines. The synthesised heterocycles were characterized on the basis of their chemical properties and spectroscopic data. These compounds were tested for antimicrobial activity against a variety of test organisms: Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Proteus mirabillis, Shigella dysentry and Salmonella typhii. The compounds containing chloro, hydroxo and dimethylamino - N(CH3)2 group as substituents on the naphthalene rings have been found to be very effective antimicrobial agents. In addition, the presence of a carboxamido -CONH2 substituent group at the N-1 position of the 2-pyrazoline rings is shown to contribute substantially to the antimicrobial activity. Full article
Open AccessArticle Determination of Aldehyde Dehydrogenase (ALDH) Isozymes in Human Cancer Samples - Comparison of Kinetic and Immunochemical Assays
Molecules 2002, 7(12), 896-901; doi:10.3390/71200896
Received: 25 October 2002 / Accepted: 4 December 2002 / Published: 31 December 2002
PDF Full-text (96 KB) | HTML Full-text | XML Full-text
Abstract
A fluorimetric assay of aldehyde dehydrogenase isozymes, based on naphthaldehyde oxidation, is compared with Western Blotting analysis on several clinical samples obtained from surgery. The comparison reveals qualitatively good correlation of ALDH1A1 isozyme detection with two methods and somewhat worse on ALDH3A1 assay.
[...] Read more.
A fluorimetric assay of aldehyde dehydrogenase isozymes, based on naphthaldehyde oxidation, is compared with Western Blotting analysis on several clinical samples obtained from surgery. The comparison reveals qualitatively good correlation of ALDH1A1 isozyme detection with two methods and somewhat worse on ALDH3A1 assay. Full article
Open AccessArticle Short and Efficient Synthesis of Optically Active N-Tosyl Aziridines from 2-Amino Alcohols
Molecules 2002, 7(12), 902-906; doi:10.3390/71200902
Received: 3 November 2002 / Revised: 2 December 2002 / Accepted: 2 December 2002 / Published: 31 December 2002
Cited by 17 | PDF Full-text (20 KB) | HTML Full-text | XML Full-text
Abstract
Two alternative and complementary one-pot procedures for the direct transformation of 2-amino alcohols to N-tosyl aziridines are presented. The unsubstituted parent compound and its less hindered homologues can be obtained in high yields by tosylation and in situ cyclisation effected by potassium hydroxide
[...] Read more.
Two alternative and complementary one-pot procedures for the direct transformation of 2-amino alcohols to N-tosyl aziridines are presented. The unsubstituted parent compound and its less hindered homologues can be obtained in high yields by tosylation and in situ cyclisation effected by potassium hydroxide in water/dichloromethane. Higher substituted amino alcohols give better yields using potassium carbonate in acetonitrile. Both procedures use simple inorganic bases and produce only inorganic salts as byproducts. Full article
Open AccessArticle Synthesis of 2-(5-Nitropyrid-2-yl)-3-(4-substitutedphenyl)aminoisoxazol-5(2H)-ones and Their Rearrangements to Imidazo[1,2-a]- pyridines and Indoles with Triethylamine
Molecules 2002, 7(12), 907-916; doi:10.3390/71200907
Received: 2 September 2002 / Revised: 30 November 2002 / Accepted: 12 December 2002 / Published: 31 December 2002
Cited by 4 | PDF Full-text (51 KB) | HTML Full-text | XML Full-text
Abstract 3-(4-Substitutedphenyl)aminoisoxazol-5(2H)-ones, substituted on nitrogen with a nitropyridine group, react with triethylamine to give imidazo[1,2-a]pyridines and indoles. With 4-bromophenyl and 4-methylphenyl group substituents only imidazopyridines are formed, but the 4-methoxyphenyl derivative gave a 3:1 mixture of the corresponding imidazo[1,2-a]pyridine and 2-pyridylaminoindole, respectively. Full article
Open AccessArticle Synthesis of 3-Alkenyl-1-azaanthraquinones via Diels-Alder and Electron Transfer Reactions
Molecules 2002, 7(12), 917-921; doi:10.3390/71200917
Received: 8 January 2002 / Revised: 16 December 2002 / Accepted: 17 December 2002 / Published: 31 December 2002
Cited by 2 | PDF Full-text (30 KB) | HTML Full-text | XML Full-text
Abstract A convenient route to 3-alkenyl-1-azaanthraquinones via a hetero Diels-Alder reaction between an azadiene and naphthoquinone, a free radical chlorination and an electron transfer reaction is reported. Full article

Other

Jump to: Editorial, Research

Open AccessCommentary The International Symposium on Frontiers in Molecular Science 2002 (ISFMS 2002), Qingdao, China, July 15-18, 2002
Molecules 2002, 7(12), 854; doi:10.3390/71200854
Published: 31 December 2002
Cited by 1 | PDF Full-text (10 KB) | HTML Full-text | XML Full-text

Journal Contact

MDPI AG
Molecules Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
molecules@mdpi.com
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
Contact Details Submit to Molecules
Back to Top