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Int. J. Mol. Sci. 2012, 13(11), 14172-14202; doi:10.3390/ijms131114172

The Innate Immune-Related Genes in Catfish

1
Liaoning Ocean and Fisheries Science Research Institute, Dalian 116023, China
2
Key Laboratory of Marine Fishery Molecular Biology of Liaoning Province, Dalian 116023, China
3
Liaoning Fisheries Technology Extension Station, Shenyang 110031, China
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 17 September 2012 / Revised: 24 October 2012 / Accepted: 25 October 2012 / Published: 2 November 2012
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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Abstract

Catfish is one of the most important aquaculture species in America (as well as in Asia and Africa). In recent years, the production of catfish has suffered massive financial losses due to pathogen spread and breakouts. Innate immunity plays a crucial role in increasing resistance to pathogenic organisms and has generated increasing interest in the past few years. This review summarizes the current understanding of innate immune-related genes in catfish, including pattern recognition receptors, antimicrobial peptides, complements, lectins, cytokines, transferrin and gene expression profiling using microarrays and next generation sequencing technologies. This review will benefit the understanding of innate immune system in catfish and further efforts in studying the innate immune-related genes in fish. View Full-Text
Keywords: catfish; channel catfish (Ictalurus punctatus); innate immunity; antimicrobial peptide; complement; lectin; cytokine; RNA-seq; gene expression profiling catfish; channel catfish (Ictalurus punctatus); innate immunity; antimicrobial peptide; complement; lectin; cytokine; RNA-seq; gene expression profiling
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Gao, L.; He, C.; Liu, X.; Su, H.; Gao, X.; Li, Y.; Liu, W. The Innate Immune-Related Genes in Catfish. Int. J. Mol. Sci. 2012, 13, 14172-14202.

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