Crosstalk between Long Noncoding RNAs and MicroRNAs in Health and Disease
Abstract
:1. Introduction
2. Interaction between Long Non-Coding RNAs and MicroRNAs in Cancers
2.1. Bladder Cancer
2.2. Breast Cancer
2.3. Gastric Cancer
2.4. Hepatocellular Carcinoma
2.5. Prostate Cancer
2.6. Colon Cancer
2.7. Renal Cell Carcinoma
2.8. Lung Cancer
3. Interaction between Long Noncoding RNAs and MicroRNAs in Cardiovascular Diseases
3.1. Atherosclerosis
3.2. Mitochondrial Homeostasis-Related Cardiac Apoptosis
3.3. Cardiac Hypertrophy
3.4. Myocardial Infarction
4. Interaction between Long Noncoding RNAs and MicroRNAs in Other Diseases
4.1. Idiopathic Pulmonary Fibrosis
4.2. Inflammation
4.3. Neurodegeneration
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Disease | LncRNA | MiRs | Target Genes | Reference |
---|---|---|---|---|
Bladder Cancer | MALAT1 | MiR-125b | SIRT7 | [17] |
Breast Cancer | HOTAIR | MiR-7 | SETDB1 | [18] |
HOTAIR | MiR-568 | NFAT5 | [19] | |
Gastric Cancer | HOTAIR | MiR-331-3p | HER2 | [20] |
FER1L4 | MiR-106a-5p | PTEN | [21] | |
MEG3 | MiR-181a | MEG3 | [22] | |
H19 | MiR-141 | ZEB1 | [23] | |
ANRIL | MiR-99a/449a | MTOR/CDK6/E2F1 | [24] | |
H19 | MiR-675 | RUNX1 | [25] | |
Glioma | HOTAIR | MiR-326 | FGF1 | [26] |
GAS5 | MiR-222 | GAS5 | [27] | |
Hepatocellular Carcinoma | HOTTIP | MiR-125b | HOXA | [28] |
HULC | MiR-372 | PRKACB | [29] | |
Prostate Cancer | PCAT-1 | MiR-3667-3p | cMYC | [30] |
Renal Cell Carcinoma | MALAT1 | MiR-205 | EZH2 | [31] |
Neurodegeneration | SCA7 | MiR-124 | ATXN7 | [32] |
Disease | LncRNA | MiRs | Target Genes | References |
---|---|---|---|---|
Atherosclerosis | RP5-833A20.1 | MiR-382-5p | NFIA | [62] |
Cardiac Apoptosis | CARL | MiR-539 | PHB2 | [4] |
Cardiac Hypertrophy | CHRF | MiR-489 | MYD88 | [63] |
Endothelial Dysfunction | MALAT1 | MiR-22-3p | CXCR2/AKT | [64] |
Myocardial Infarction | APF H19 | MiR-188-3p MiR-103/107 | ATG7 FADD | [65] [66] |
Ventricular Septal Defect | MALAT 1 | MiR-133 | SRF | [67,68] |
© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
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Bayoumi, A.S.; Sayed, A.; Broskova, Z.; Teoh, J.-P.; Wilson, J.; Su, H.; Tang, Y.-L.; Kim, I.-m. Crosstalk between Long Noncoding RNAs and MicroRNAs in Health and Disease. Int. J. Mol. Sci. 2016, 17, 356. https://doi.org/10.3390/ijms17030356
Bayoumi AS, Sayed A, Broskova Z, Teoh J-P, Wilson J, Su H, Tang Y-L, Kim I-m. Crosstalk between Long Noncoding RNAs and MicroRNAs in Health and Disease. International Journal of Molecular Sciences. 2016; 17(3):356. https://doi.org/10.3390/ijms17030356
Chicago/Turabian StyleBayoumi, Ahmed S., Amer Sayed, Zuzana Broskova, Jian-Peng Teoh, James Wilson, Huabo Su, Yao-Liang Tang, and Il-man Kim. 2016. "Crosstalk between Long Noncoding RNAs and MicroRNAs in Health and Disease" International Journal of Molecular Sciences 17, no. 3: 356. https://doi.org/10.3390/ijms17030356