Relation of Plasma Catecholamine Concentrations and Myocardial Mitochondrial Respiratory Activity in Anesthetized and Mechanically Ventilated, Cardiovascular Healthy Swine
Abstract
:1. Introduction
2. Results
3. Discussion
Limitations of the Study
4. Materials and Methods
4.1. Anesthesia and Surgery
4.2. Experimental Protocol
4.3. Measurements and Calculations
4.4. Data Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Adrenaline [pg/mL] | Noradrenaline [pg/mL] | Isoprostane [pg/mL] | O2•− [μmol/L] | Tail Moment |
---|---|---|---|---|
75 (28; 143) | 127 (92; 228) | 43 (39; 47) | 3.8 (3.5; 4.6) | 0.16 (0.15; 0.18) |
JO2 -OxPhos [pmol/s/mgtissue] | JO2-ETC [pmol/s/mgtissue] | Complex I [%] | Complex II [%] | β2-Adrenoreceptor [%] |
---|---|---|---|---|
194 (110; 223) | 222 (158; 261) | 86 (78; 89) | 71 (60; 82) | 83 (70; 89) |
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Abele, N.; Münz, F.; Zink, F.; Gröger, M.; Hoffmann, A.; Wolfschmitt, E.-M.; Hogg, M.; Calzia, E.; Waller, C.; Radermacher, P.; et al. Relation of Plasma Catecholamine Concentrations and Myocardial Mitochondrial Respiratory Activity in Anesthetized and Mechanically Ventilated, Cardiovascular Healthy Swine. Int. J. Mol. Sci. 2023, 24, 17293. https://doi.org/10.3390/ijms242417293
Abele N, Münz F, Zink F, Gröger M, Hoffmann A, Wolfschmitt E-M, Hogg M, Calzia E, Waller C, Radermacher P, et al. Relation of Plasma Catecholamine Concentrations and Myocardial Mitochondrial Respiratory Activity in Anesthetized and Mechanically Ventilated, Cardiovascular Healthy Swine. International Journal of Molecular Sciences. 2023; 24(24):17293. https://doi.org/10.3390/ijms242417293
Chicago/Turabian StyleAbele, Nadja, Franziska Münz, Fabian Zink, Michael Gröger, Andrea Hoffmann, Eva-Maria Wolfschmitt, Melanie Hogg, Enrico Calzia, Christiane Waller, Peter Radermacher, and et al. 2023. "Relation of Plasma Catecholamine Concentrations and Myocardial Mitochondrial Respiratory Activity in Anesthetized and Mechanically Ventilated, Cardiovascular Healthy Swine" International Journal of Molecular Sciences 24, no. 24: 17293. https://doi.org/10.3390/ijms242417293