Next Issue
Volume 2013, September
Previous Issue
Volume 2013, March
 
 

Molbank, Volume 2013, Issue 2 (June 2013) – 6 articles

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Section
Select all
Export citation of selected articles as:
89 KiB  
Short Note
2'-[(4-Fluorophenyl)carbonyl]-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indole-3,3'-pyrrolizin]-2(1H)-one
by Majal Sapnakumari, Badiadka Narayana, Seranthimata Samshuddin and Balladka Kunhanna Sarojini
Molbank 2013, 2013(2), M802; https://doi.org/10.3390/M802 - 23 May 2013
Cited by 2 | Viewed by 3319
Abstract
A new spiro[indole-3,3'-pyrrolizine] derivative is regioselectively synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en-1-one, isatin and L-proline without any catalyst. The structure of the newly synthesized compound is characterized by IR, NMR, UV-visible and mass spectral data. The compound is also screened for [...] Read more.
A new spiro[indole-3,3'-pyrrolizine] derivative is regioselectively synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en-1-one, isatin and L-proline without any catalyst. The structure of the newly synthesized compound is characterized by IR, NMR, UV-visible and mass spectral data. The compound is also screened for its reducing power assay. Full article
Show Figures

Graphical abstract

188 KiB  
Short Note
(R)-7-(Azepan-3-ylamino)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride
by Zhengjun Xia, Zaixin Chen and Shuitao Yu
Molbank 2013, 2013(2), M801; https://doi.org/10.3390/M801 - 22 May 2013
Viewed by 3992
Abstract
In this paper (R)-7-(azepan-3-ylamino)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 1 was isolated and identified as the N-substituted regioisomer of besifloxacin, which has been synthesized from the reaction of 8-chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 3 with (R)-tert-butyl 3-aminoazepane-1-carboxylate 2 in acetonitrile as solvent in 37% [...] Read more.
In this paper (R)-7-(azepan-3-ylamino)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 1 was isolated and identified as the N-substituted regioisomer of besifloxacin, which has been synthesized from the reaction of 8-chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 3 with (R)-tert-butyl 3-aminoazepane-1-carboxylate 2 in acetonitrile as solvent in 37% yield. The chemical structure of compound 1 was established on the basis of 1H-NMR, 13C-NMR, mass spectrometry data and elemental analysis. Full article
Show Figures

Graphical abstract

68 KiB  
Short Note
2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide
by Prakash S. Nayak, Badiadka Narayana, Seranthimata Samshuddin and Balladka Kunhanna Sarojini
Molbank 2013, 2013(2), M800; https://doi.org/10.3390/M800 - 03 May 2013
Cited by 1 | Viewed by 4459
Abstract
S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) [...] Read more.
S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data. Full article
Show Figures

Graphical abstract

137 KiB  
Short Note
3,3'-(1,4-Phenylenebis(phenylazanediyl))bis(7-ethoxy-4-methyl-2H-chromen-2-one)
by Divia Narayanan and Karickal Raman Haridas
Molbank 2013, 2013(2), M799; https://doi.org/10.3390/M799 - 02 May 2013
Cited by 1 | Viewed by 3419
Abstract
3,3'-(1,4-Phenylenebis(phenylazanediyl))bis(7-ethoxy-4-methyl-2H-chromen-2-one) was synthesized from N,N'-diphenylbenzene-1,4-diamine and bromo-7-ethoxy-4-methylcoumarin based on Ullmann coupling reaction. The synthesized compound was characterized by UV-Visible, NMR, FT-IR, MS, elemental analysis and Fluorescence Spectrum. Full article
Show Figures

Graphical abstract

132 KiB  
Short Note
N"-[(3Z)-1-Acetyl-5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene]thiocarbonohydrazide
by Nataša Ristovska, Frosa Anastasova and Marina Stefova
Molbank 2013, 2013(2), M798; https://doi.org/10.3390/M798 - 16 Apr 2013
Cited by 3 | Viewed by 4662
Abstract
A novel synthetic methodology for preparation of thiocarbohydrazone by reacting thiocarbohydrazide with 1-acetyl-5-chloroisatin is described. The title compound was prepared by condensation of thiocarbohydrazide and substituted isatin in aqueous ethanol. The newly synthesized compound was characterized using 1H-NMR, 13C-NMR, FT-IR and [...] Read more.
A novel synthetic methodology for preparation of thiocarbohydrazone by reacting thiocarbohydrazide with 1-acetyl-5-chloroisatin is described. The title compound was prepared by condensation of thiocarbohydrazide and substituted isatin in aqueous ethanol. The newly synthesized compound was characterized using 1H-NMR, 13C-NMR, FT-IR and mass spectrometry. Full article
Show Figures

Graphical abstract

119 KiB  
Short Note
2-Chloro-7-methyl-3-({4-[(4-nitrophenoxy)methyl]-1H-1,2,3-triazol-1-yl}methyl)quinoline
by Koduru Sri Shanthi Praveena, Nandula Yadagiri Sreenivasa Murthy and Sarbani Pal
Molbank 2013, 2013(2), M797; https://doi.org/10.3390/M797 - 11 Apr 2013
Viewed by 3715
Abstract
The title compound, 2-chloro-7-methyl-3-({4-[(4-nitrophenoxy)methyl]-1H-1,2,3-triazol-1-yl}methyl)quinoline was synthesized in one pot. The structure of the compound was fully characterized by IR, 1H and 13C-NMR, mass spectral analysis and elemental analysis. Full article
Show Figures

Graphical abstract

Previous Issue
Back to TopTop