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Pediatric Reports
Volume 8
Issue 1
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Pediatric Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Pediatr. Rep., Volume 8, Issue 1 (March 2016) – 4 articles

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590 KiB  
Case Report
Rarely Seen Nasal Congenital Problems Causing Neonatal Upper Respiratory Obstruction: A Case Series
by Yeşim Başal, Abdullah Bariş Akcan, Yasemin Durum Polat, Ceren Günel, Aylin Eryilmaz and Sema Başak
Pediatr. Rep. 2016, 8(1), 6456; https://doi.org/10.4081/pr.2016.6456 - 31 Mar 2016
Cited by 10 | Viewed by 473
Abstract
Since newborns are obligatory nasal breathers, upper respiratory tract problems may sometimes be life threatening. The most common pathology causing dyspnea and stridor in newborns is laryngomalacia. Nasal cavity pathologies that risk the neonatal airway are more rarely met. These anomalies may be [...] Read more.
Since newborns are obligatory nasal breathers, upper respiratory tract problems may sometimes be life threatening. The most common pathology causing dyspnea and stridor in newborns is laryngomalacia. Nasal cavity pathologies that risk the neonatal airway are more rarely met. These anomalies may be seen either as solitary anomalies or as a part of a syndrome. While choanal atresia is one of the best-known nasal cavity anomalies, choanal stenosis, congenital nasal mid-line masses, congenital nasal pyriform aperture stenosis, and nasal tip anomalies are more rarely seen structural pathologies. Choanal atresia may be present either as an isolated congenital anomaly or as a part of CHARGE syndrome. Some rare chromosome anomalies may also cause significant problems during nasal respiration in newborns. With this study, we presented a case series of newborns with pathologies that affected nasal respiration. Although the diagnosis and treatment of choanal atresia and congenital dacryocystocele are well known, the information on the diagnosis and treatment of the other two uncommon cases are limited. With this study, we aimed to contribute to the literature by presenting our approach in six cases having congenital pathologies that cause nasal respiratory obstruction. Full article
574 KiB  
Case Report
Is There Any Relationship Between Extra-Pulmonary Manifestations of Mycoplasma Pneumoniae Infection and Atopy/Respiratory Allergy in Children?
by Dimitri Poddighe and Gian Luigi Marseglia
Pediatr. Rep. 2016, 8(1), 6395; https://doi.org/10.4081/pr.2016.6395 - 31 Mar 2016
Cited by 27 | Viewed by 520
Abstract
Mycoplasma pneumoniae is a common cause of respiratory infections in children, but sometimes extra-pulmonary diseases can be observed. The immunological mechanisms involved in these extra-respiratory complications are unknown. Here, we report a small case series of Mycoplasma-related diseases including 5 children who developed: [...] Read more.
Mycoplasma pneumoniae is a common cause of respiratory infections in children, but sometimes extra-pulmonary diseases can be observed. The immunological mechanisms involved in these extra-respiratory complications are unknown. Here, we report a small case series of Mycoplasma-related diseases including 5 children who developed: i) aseptic meningitis; ii) urticarial rash and pericardial effusion; iii) pleural effusion with severe eosinophilia; iv) Stevens-Johnson syndrome; v) multiform erythema. Interestingly, all children were moderately to highly atopic, as a common immunologic feature. Full article
574 KiB  
Article
Salivary Cortisol Levels: The Importance of Clown Doctors to Reduce Stress
by Flávia G. Saliba, Natanael S. Adiwardana, Eliane U. Uehara, Renata N. Silvestre, Victor V. Leite, Francisca T.V. Faleiros, Flávia H.P. Padovani and Juliana I.F. De Gobbi
Pediatr. Rep. 2016, 8(1), 6188; https://doi.org/10.4081/pr.2016.6188 - 31 Mar 2016
Cited by 17 | Viewed by 1463
Abstract
This study was designed to correlate entertainment of clown-doctors (CD) activities on hospitalized children and aphysiological biomarker. For this purpose we collected saliva samples and verified children satisfaction with these activities by using a visual analog scale (VAS). Children from 6 to 7 [...] Read more.
This study was designed to correlate entertainment of clown-doctors (CD) activities on hospitalized children and aphysiological biomarker. For this purpose we collected saliva samples and verified children satisfaction with these activities by using a visual analog scale (VAS). Children from 6 to 7 years-old, with diagnosis of any acute pathology, interned in the Pediatric Ward of the Botucatu Medical School Hospital (São Paulo, Brazil) were interviewed. Two groups were taken into consideration: lunchCD and dinnerCD. The following protocol was applied in each group (lunch and dinner): collection of the first saliva sample and presentation of VAS prior to CD activities, followed by collection of a second saliva sample and another VAS assessment after CD activities. The salivary cortisol was reduced in both groups comparing the first saliva sample. The satisfaction of the intervention was evident for lunchCD. The CD intervention is effective in decreasing an important physiological biomarker of stress factor, cortisol, in hospitalized children, been effective for the healing process. Full article
555 KiB  
Case Report
The Use of Splenectomy to Manage Platelet Transfusion Refractoriness Due to Anti-Human Leukocyte Antibodies in Allogeneic Stem Cell Transplantation
by Margherita Mauro, Francesco Camoglio, Pierluigi Piccoli, Massimiliano De Bortoli, Rita Balter, Anna Pegoraro and Simone Cesaro
Pediatr. Rep. 2016, 8(1), 6159; https://doi.org/10.4081/pr.2016.6159 - 31 Mar 2016
Cited by 8 | Viewed by 486
Abstract
In patients undergoing hematopoietic stem cell transplantation (HSCT), refractoriness to platelet transfusion has been associated with graft failure, delayed engraftment, early mortality and decreased overall survival. Therapeutic strategies include plasma exchange, immunoglobulins, rituximab, and splenectomy. We describe here three patients with refractoriness to [...] Read more.
In patients undergoing hematopoietic stem cell transplantation (HSCT), refractoriness to platelet transfusion has been associated with graft failure, delayed engraftment, early mortality and decreased overall survival. Therapeutic strategies include plasma exchange, immunoglobulins, rituximab, and splenectomy. We describe here three patients with refractoriness to platelet transfusion due to anti-human leukocyte antibodies who were splenectomized before HSCT (two cases) and after HSCT (one case) due to the lack of efficacy of other therapies. Splenectomy was uneventful. All three patients achieved a full donor engraftment. We suggest that splenectomy is feasible and effective in HSCT patients to reduce the risk of graft failure or delayed engraftment. Full article
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