Protein Intake and Frailty in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies
, Riccardo Calvani 2,*, Anna Picca 2, Matteo Tosato 2, Francesco Landi 1,2 and Emanuele Marzetti 1,2
Round 1
Reviewer 1 Report
Manuscript Number: nutrients-1799711
Title: Protein intake and frailty in older adults: a systematic review and meta-analysis of observational studies
The paper titled, " Protein intake and frailty in older adults: a systematic review and meta-analysis of observational studies", is reasonably well written and well organized.
The authors have presented the study in a systematic manner.
The authors thoroughly reviewed the literature for writing up this article.
The global message of the manuscript is clear and brings solid pieces of evidence and data.
The role of statistics in the systematic review process is extremely important. The authors used the proper statistical method to determine the crucial measurements to verify the validity and applicability of their systematic review.
This article can be an important consideration for many investigators.
Congratulations on an interesting job.
Reviewer 2 Report
This is a review article to address a systematic review and meta-analysis of observational studies Protein intake and frailty in older adults. The authors’ pooled analysis indicates that protein intake, whether absolute, adjusted or relative to total energy intake, is significantly associated with frailty in older adults. However, we observed that frail older adults consumed significantly less animal protein than their robust counterparts. That is interesting and helpful.
