Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice
Abstract
:1. Introduction
2. Materials and Methods
2.1. Strain
2.2. Animals
2.3. Isolated and Identified
2.4. Survival Rate in Simulated Gastric Juice
2.5. Bile Salt Tolerance
2.6. Induction of Colitis in Mice
2.7. Collection of Samples
2.8. Histological Observations
2.9. Measurement of Cytokine in the Serum
2.10. Western Blot Analysis
2.11. Statistical Analysis
3. Results
3.1. Strain
3.2. In Vitro Characteristics of Strain
3.3. Colon Weight and Length
3.4. Histological Analyses
3.5. IL-6, IL-12, INF-γ, and TNF-α Concentrations in Serum
3.6. Western Blot
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Strain | Survival in PH 3.0 Simulated Gastric Juice (%) | Growth Efficiency in Bile Salt (%) | |||
---|---|---|---|---|---|
0.05 | 0.1 | 0.2 | 0.3 | ||
LF-HY01 | 103.73 ± 8.60 | 98.30 + 0.09 | 61.50 ± 0.45 | 29.40 ± 0.80 | 21.62 ± 0.86 |
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Chen, X.; Zhao, X.; Wang, H.; Yang, Z.; Li, J.; Suo, H. Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice. Nutrients 2017, 9, 545. https://doi.org/10.3390/nu9060545
Chen X, Zhao X, Wang H, Yang Z, Li J, Suo H. Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice. Nutrients. 2017; 9(6):545. https://doi.org/10.3390/nu9060545
Chicago/Turabian StyleChen, Xiaoyong, Xin Zhao, Hongwei Wang, Zelin Yang, Jian Li, and Huayi Suo. 2017. "Prevent Effects of Lactobacillus Fermentum HY01 on Dextran Sulfate Sodium-Induced Colitis in Mice" Nutrients 9, no. 6: 545. https://doi.org/10.3390/nu9060545