Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients—In Depth Characterization with Same Day MRI and CT Discography
Abstract
:1. Introduction
2. Materials and Methods
2.1. Reliability Measures
2.2. Statistics
3. Results
3.1. Distribution of Morphological Changes within the Cohort
3.2. Intervertebral Disc Changes Discs in Relation to Endplate Score and Modic Changes
Number of Intervertebral Discs Affected (%) | Number of Endplate Segments Affected (%) | Number of Vertebral Units Affected (%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
MRI n = 204 | CT discograms n = 194 | MRI/CT combined n = 204 | MRI n = 408 | ||||||||
Pfirrmann Grade | HIZ | Outer Annular Fissure | Delimitable Fissures | Endplate Defect Score | Modic Change MC | Sclerosis on CT Stratified by MC | |||||
MC type 1 | 10 (2.5) | 5 (50) | |||||||||
1 | 0 | yes | 95 (46.6) | yes = DDS ≥ 1 | 160 (82.5) | 91 (46.9) | 1 | 49 (24.0) | MC type 2 | 66 (16.1) | 41 (62.1) |
2 | 32 (15.7) | no | 109 (53.4) | no = DDS 0 | 34 (17.5) | 2 | 65 (31.9) | MC type 3 | 3 (0.7) | 3 (100) | |
3 | 72 (35.3) | 3 | 51 (25.0) | MC mix 1&2 | 15 (3.7) | 13 (86.7) | |||||
4 | 83 (40.7) | 4 | 31 (15.2) | MC mix 2&3 | 9 (2.2) | 8 (88.9) | |||||
5 | 17 (8.3) | 5 | 8 (3.9) | MC mix 1&3 | 8 (2.0) | 7 (87.5) | |||||
no MC | 297 (72.8) | 28 (9.4) |
3.3. Coexistence of Modic Changes and Endplate Score
3.4. Sclerosis in Relation to Modic Changes and Annular Fissures
3.5. Contrast Extending into the Vertebrae
3.6. Reliability Measures
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Endplate Score | Combined Apperance on CT/MRI | |||
---|---|---|---|---|
1 | 2 | 3 | 4 | 5 |
normal | focal disc contact/maintained contour | defects > 25% | defects up to 50% | extensive erosions/total destruction |
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Hebelka, H.; Erkmar, A.; Brisby, H.; Lagerstrand, K. Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients—In Depth Characterization with Same Day MRI and CT Discography. Diagnostics 2023, 13, 3528. https://doi.org/10.3390/diagnostics13233528
Hebelka H, Erkmar A, Brisby H, Lagerstrand K. Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients—In Depth Characterization with Same Day MRI and CT Discography. Diagnostics. 2023; 13(23):3528. https://doi.org/10.3390/diagnostics13233528
Chicago/Turabian StyleHebelka, Hanna, Alfred Erkmar, Helena Brisby, and Kerstin Lagerstrand. 2023. "Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients—In Depth Characterization with Same Day MRI and CT Discography" Diagnostics 13, no. 23: 3528. https://doi.org/10.3390/diagnostics13233528