Next Issue
Previous Issue

Table of Contents

Diagnostics, Volume 2, Issue 2 (June 2012), Pages 2-22

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
View options order results:
result details:
Displaying articles 1-2
Export citation of selected articles as:

Research

Open AccessArticle Intra-/Interobserver Agreement of Enhancement Pattern for Pancreatic Head Lesions Using Contrast-Enhanced Ultrasound: According to EFSUMB Guidelines
Diagnostics 2012, 2(2), 2-9; doi:10.3390/diagnostics2020002
Received: 27 February 2012 / Revised: 22 March 2012 / Accepted: 29 March 2012 / Published: 20 April 2012
PDF Full-text (358 KB) | HTML Full-text | XML Full-text
Abstract
Objective: To evaluate the intra-/interobserver agreement of the visual interpretation of contrast-enhanced ultrasound (CEUS) of pancreatic head lesions and its concordance with the histological test results. Material and Methods: Two observers (A + B) evaluated by simple visual interpretation 40 consecutive
[...] Read more.
Objective: To evaluate the intra-/interobserver agreement of the visual interpretation of contrast-enhanced ultrasound (CEUS) of pancreatic head lesions and its concordance with the histological test results. Material and Methods: Two observers (A + B) evaluated by simple visual interpretation 40 consecutive CEUS examinations of pancreatic head lesions and one of the observers evaluated the examinations twice (A1 + A2). The examinations were evaluated according to the criteria outlined in EFSUMB guidelines. The two experienced observers were blinded to histological evidence and clinical information of tumor type and to each other’s results. Results: The kappa value for the intraobserver evaluation between observer A1 and A2 was 0.89, equating to almost perfect agreement. The kappa value for the interobserver evaluation between observer A1 and B was 0.76 and between observer A2 and B it was 0.75, both equating to substantial agreement. Evaluation of the visual interpretation compared to the histological test result showed a positive predictive value for A1, A2 and B versus biopsy of 97%, 94% and 90% respectively and an accuracy of 83%, 88% and 73% respectively. Conclusions: Visual interpretation for assessment of contrast enhancement of pancreatic head lesions seemed to be an accurate method with reproducible results and good concordance with the histological test results. Full article
Open AccessArticle The Combination of In vivo 124I-PET and CT Small Animal Imaging for Evaluation of Thyroid Physiology and Dosimetry
Diagnostics 2012, 2(2), 10-22; doi:10.3390/diagnostics2020010
Received: 27 April 2012 / Revised: 24 May 2012 / Accepted: 29 May 2012 / Published: 5 June 2012
PDF Full-text (507 KB) | HTML Full-text | XML Full-text
Abstract
Objective: A thyroid rat model combining functional and anatomical information would be of great benefit for better modeling of thyroid physiology and for absorbed dose calculations. Our aim was to show that 124I-PET and CTsmall animal imaging are useful as
[...] Read more.
Objective: A thyroid rat model combining functional and anatomical information would be of great benefit for better modeling of thyroid physiology and for absorbed dose calculations. Our aim was to show that 124I-PET and CT small animal imaging are useful as a combined model for studying thyroid physiology and dose calculation. Methods: Seven rats were subjects for multiple thyroid 124I-imaging and CT-scans. S-values [mGy/MBqs] for different thyroid sizes were simulated. A phantom with spheres was designed for validation of performances of the small animal PET and CT imaging systems. Results: Small animal image-based measurements of the activity amount and the volumes of the spheres with a priori known volumes showed a good agreement with their corresponding actual volumes. The CT scans of the rats showed thyroid volumes from 34–70 mL. Conclusions: The wide span in volumes of thyroid glands indicates the importance of using an accurate volume-measuring technique such as the small animal CT. The small animal PET system was on the other hand able to accurately estimate the activity concentration in the thyroid volumes. We conclude that the combination of the PET and CT image information is essential for quantitative thyroid imaging and accurate thyroid absorbed dose calculation. Full article

Journal Contact

MDPI AG
Diagnostics Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
diagnostics@mdpi.com
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
Contact Details Submit to Diagnostics
Back to Top