The Relationship of Latent Toxoplasmosis and Cigarette Smoking: Seroprevalence, Risk Factor, and Case-Control Study in Fars Province, Southern Iran
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethics Approval
2.2. Sampling
2.3. ELISA for Detection of IgG Antibodies to Toxoplasma Gondii
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Test Result | Median Age | Frequency to Toxoplasma Infection (%) | ||||
---|---|---|---|---|---|---|
Case | Control | Total | Case | Control | Total | |
Positive | 63.27 | 53.64 | 56.81 | 44 (20.37%) | 135 (41.67%) | 179 (33.14%) |
Negative | 47.9 | 49.16 | 48.44 | 172 (79.63%) | 189 (58.33%) | 361 (66.86%) |
Total | 51.04 | 51.03 | 51.03 | 216 (100%) | 324 (100%) | 540 (100%) |
Characteristics | Frequency (No.) | Per Cent (%) | Toxoplasma Seroprevalence No. (%) | Univariate Analysis | Multivariate Analysis | |||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | Case | Control | OR (95% CI) | p Value | OR (95% CI) | p Value | |
Residence area | ||||||||||
Urban | 200 | 303 | 92.6 | 93.5 | 36 (81.8) | 126 (93.3%) | 2.056 (0.71–5.92) | 0.18 | 1.9 (0.62–5.8) | 0.26 |
Rural | 16 | 21 | 7.4 | 6.5 | 8 (18.2) | 9 (6.7%) | 1 | - | 1 | - |
Presence of a cat in the household | ||||||||||
Yes | 16 | 18 | 7.4 | 5.6 | 4 (9.1) | 12 (8.9) | 0.57 (0.19–1.73) | 0.32 | 0.59 (0.12–1.3) | 0.14 |
No | 200 | 306 | 92.6 | 94.4 | 40 (90.9) | 123 (90.1) | 1 | - | 1 | - |
Age (Years) | ||||||||||
<30 | 40 | 36 | 18.5 | 11.1 | 0 (0%) | 12 (8.9%) | 1 | - | 1 | - |
31–45 | 40 | 93 | 18.5 | 28.7 | 0 (0%) | 36 (26.7%) | 0.46 (0.13–1.6) | 0.22 | 0.41 (0.11–1.53) | 0.18 |
46–60 | 64 | 87 | 29.6 | 26.9 | 24 (54.5%) | 33 (24.4%) | 0.23 (0.073–0.76) | 0.015 | 0.16 (0.04–0.63 | 0.008 |
>60 | 72 | 108 | 33.3 | 33.3 | 20 (45.5) | 54 (40%) | 0.22 (0.071–0.7) | 0.011 | 0.16 (0.042–0.69) | 0.01 |
Duration of addiction | ||||||||||
<5 | 40 | - | 18.5 | - | 0 (0%) | - | - | 0.99 | 1 | - |
6–10 | 32 | - | 14.8 | - | 0 (0%) | - | 0.94 (1.6–5.6) | 0.95 | 0.53 (0.04–7.04) | 0.63 |
11–15 | 28 | 13 | 4 (9.1%) | - | 0.99 | 1 | - | |||
16–20 | 12 | - | 5.6 | - | 4 (9.1%) | - | 3 (0.31–28.8) | 0.34 | 1.73 (0.11–25.5) | 0.68 |
>20 | 104 | - | 48.1 | - | 36 (81.8%) | - | 1 | - | 1 | - |
Age at onset of smoking | ||||||||||
<30 | 140 | - | 64.8 | - | 20 (45.4%) | - | 1 | - | 1 | - |
31–40 | 48 | - | 22.2 | - | 16 (36.3%) | - | 0.33 (0.11–0.98) | 0.046 | 0.55 (0.12–2.6) | 0.45 |
>40 | 28 | - | 13 | - | 8 (18.3) | - | 0.41 (0.1–1.6) | 0.2 | 1 (0.11–8.7) | 0.99 |
Educational level | ||||||||||
Below high school | 68 | 111 | 31.5 | 34.3 | 20 (29.4%) | 51 (37.8%) | 0. 27 (0.085–0.86) | 0.028 | 0.63 (0.17–2.3) | 0.48 |
High school | 84 | 117 | 38.9 | 36.1 | 16 (19%) | 45 (33.3%) | 0.42 (0.13–1.34) | 0.144 | 0.7 (0.2–2.4) | 0.57 |
Bachelor graduates | 32 | 60 | 14.8 | 18.5 | 8 (12.5) | 27 (20%) | 0.295 (0.084–1.03) | 0.057 | 0.24 (0.06–0.91) | 0.03 |
Higher bachelor’s degree | 32 | 36 | 14.8 | 11.1 | 0 (0%) | 12 (8.9%) | 1 | - | 1 | - |
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Bahreini, M.S.; Sami Jahromi, S.; Radfar, A.H.; Salemi, A.M.; Dastan, N.; Asgari, Q. The Relationship of Latent Toxoplasmosis and Cigarette Smoking: Seroprevalence, Risk Factor, and Case-Control Study in Fars Province, Southern Iran. Pathogens 2022, 11, 1274. https://doi.org/10.3390/pathogens11111274
Bahreini MS, Sami Jahromi S, Radfar AH, Salemi AM, Dastan N, Asgari Q. The Relationship of Latent Toxoplasmosis and Cigarette Smoking: Seroprevalence, Risk Factor, and Case-Control Study in Fars Province, Southern Iran. Pathogens. 2022; 11(11):1274. https://doi.org/10.3390/pathogens11111274
Chicago/Turabian StyleBahreini, Mohammad Saleh, Sareh Sami Jahromi, Amir Hossein Radfar, Amir Masoud Salemi, Naghmeh Dastan, and Qasem Asgari. 2022. "The Relationship of Latent Toxoplasmosis and Cigarette Smoking: Seroprevalence, Risk Factor, and Case-Control Study in Fars Province, Southern Iran" Pathogens 11, no. 11: 1274. https://doi.org/10.3390/pathogens11111274