Treatment of Rifampicin-Resistant Tuberculosis Disease and Infection in Children: Key Updates, Challenges and Opportunities
Round 1
Reviewer 1 Report
This review has focused on the covering different aspects of rifampicin-resistant (RR) tuberculosis in children. Authors have done an excellent job in updating about current challenges in detection and treatment of RR-TB in children. Since the review is focused on the RR-TB in children, authors should accordingly change the title to reflect that. The current title “Treatment of rifampicin-resistant tuberculosis disease and infection: key updates, challenges and opportunities” suggests that the review is about the RR-TB in general which is not the case.
Author Response
Thank you for your time in reviewing this paper and for your suggested correction - thank you! We have amended the title to read: "Treatment of rifampicin-resistant tuberculosis disease and infection in children: key updates, challenges and opportunities"
Reviewer 2 Report
This manuscript provides clinicians and pediatricians involved in the treatment of very difficult patient with an important work tool.
The issue of MDR-TB is addressed with an extensive literature.
The most recent guidelines for the treatment of MDR are reported.
Author Response
Thank you for your time in reviewing our paper and for the kind words.