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Journal of Clinical Medicine, Volume 12, Issue 15

2023 August-1 - 287 articles

Cover Story: The diagnosis and treatment of myocarditis is still a major clinical challenge. Despite the development of new imaging techniques, endomyocardial biopsy remains the gold standard for the accurate diagnosis of inflammatory heart disease. With the introduction and continued development of inflammatory diagnostics in combination with viral nucleic acid testing, myocarditis diagnostics have improved significantly since its introduction. Together with new technologies such as miRNA and gene expression profiling, quantification of specific immune cell markers, and determination of viral activity, diagnostic accuracy and patient prognosis will continue to improve in the future. Here, we highlight the current state of knowledge on the pathogenesis and diagnosis of inflammatory myocardial diseases, and present future perspectives for more in-depth biopsy diagnostics and personalized therapy. View this paper
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Articles (287)

  • Article
  • Open Access
6 Citations
3,872 Views
9 Pages

Association between Serum Varicella-Zoster Virus IgM and IgG and Prognosis of Ramsay Hunt Syndrome

  • Seok Hwan Chung,
  • Jung Min Kim,
  • Hwa Sung Rim,
  • Seung Geun Yeo and
  • Sang Hoon Kim

7 August 2023

Ramsay Hunt syndrome (RHS) has a poor prognosis because of varicella-zoster virus (VZV) infection. This is most closely related to severe inflammation in the geniculate ganglion of the facial nerve due to VZV infection or reactivation. This study inv...

(This article belongs to the Section Otolaryngology)
  • Systematic Review
  • Open Access
13 Citations
4,568 Views
13 Pages

Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review

  • Jack Charles Barton,
  • Anna Wozniak,
  • Chloe Scott,
  • Abhisekh Chatterjee,
  • Greg Nathan Titterton,
  • Amber Elyse Corrigan,
  • Ashvin Kuri,
  • Viraj Shah,
  • Ian Soh and
  • Juan Carlos Kaski

7 August 2023

Between-sex differences in the presentation, risk factors, management, and outcomes of acute myocardial infarction (MI) are well documented. However, as such differences are highly sensitive to cultural and social changes, there is a need to continuo...

(This article belongs to the Special Issue New Perspectives on Cardiovascular Disease: Women's Treatment and Management)
  • Review
  • Open Access
16 Citations
4,650 Views
16 Pages

Endocrine Side Effects in Patients Treated with Immune Checkpoint Inhibitors: A Narrative Review

  • Nicia I. Profili,
  • Roberto Castelli,
  • Antonio Gidaro,
  • Alessandro Merella,
  • Roberto Manetti,
  • Giuseppe Palmieri,
  • Margherita Maioli and
  • Alessandro P. Delitala

7 August 2023

Checkpoint inhibitors are monoclonal antibodies that elicit an anti-tumor response by stimulating immune system. Their use has improved the treatment of different types of cancer such as melanoma, breast carcinoma, lung, stomach, colon, liver, renal...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
37 Citations
3,038 Views
12 Pages

Does Screening for Bipolar Disorders Identify a “Dysregulation of Mood, Energy, and Social Rhythms Syndrome” (DYMERS)? A Heuristic Working Hypothesis

  • Mauro Giovanni Carta,
  • Goce Kalcev,
  • Michele Fornaro,
  • Samantha Pinna,
  • Cesar Ivan Aviles Gonzalez,
  • Antonio Egidio Nardi and
  • Diego Primavera

7 August 2023

The aim of this paper is to verify if people with a positive score on the Mood Disorder Questionnaire (MDQ) without comorbidity of mood disorders showed a worse level of Health-related Quality of life (HRQol) compared to a control-matched sample of M...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
5 Citations
2,534 Views
14 Pages

Genetic Characteristics of Latvian Patients with Familial Hypercholesterolemia: The First Analysis from Genome-Wide Sequencing

  • Gustavs Latkovskis,
  • Raimonds Rescenko-Krums,
  • Georgijs Nesterovics,
  • Monta Briviba,
  • Vita Saripo,
  • Dainus Gilis,
  • Elizabete Terauda,
  • Ruta Meiere,
  • Gunda Skudrina and
  • Janis Klovins
  • + 3 authors

7 August 2023

Background: There is limited data on the genetic characteristics of patients with familial hypercholesterolemia (FH) in Latvia. We aim to describe monogenic variants in patients from the Latvian Registry of FH (LRFH). Methods: Whole genome sequencing...

(This article belongs to the Section Cardiovascular Medicine)
  • Correction
  • Open Access
1 Citations
1,592 Views
2 Pages
  • Review
  • Open Access
4 Citations
4,059 Views
18 Pages

7 August 2023

Atrial fibrillation (AF) is the most common atrial tachyarrhythmia. One of the methods of AF treatment is direct current cardioversion (DCCV), but in the long-term follow-up we observe quite a high percentage of AF recurrences after this procedure. I...

(This article belongs to the Special Issue New Frontiers in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders)
  • Article
  • Open Access
19 Citations
4,111 Views
17 Pages

7 August 2023

This article discusses the development and preliminary validation of a self-report inventory of the patient’s perception of, and affective reaction to, their therapist during a psychotherapy session. First, we wrote a pool of 131 items, reviewe...

(This article belongs to the Section Mental Health)
  • Systematic Review
  • Open Access
4 Citations
3,628 Views
15 Pages

Patient-Reported Outcome Measures in Patients with Thrombotic Thrombocytopenic Purpura: A Systematic Review of the Literature

  • Alexandre Soares Ferreira Junior,
  • Morgana Pinheiro Maux Lessa,
  • Samantha Kaplan,
  • Theresa M. Coles,
  • Deirdra R. Terrell and
  • Oluwatoyosi A. Onwuemene

7 August 2023

Health-related quality of life (HRQoL) impacts of thrombotic thrombocytopenic purpura (TTP) have been captured in clinical studies using patient-reported outcome (PRO) measures (PROMs) that are validated for other diseases. However, the validity evid...

(This article belongs to the Special Issue New Diagnostic and Therapeutic Aspects of Thrombotic Thrombocytopenic Purpura)
  • Article
  • Open Access
4 Citations
3,892 Views
17 Pages

Massive Transfusion Increases Serum Magnesium Concentration

  • Justyna Malinowska,
  • Milena Małecka-Giełdowska,
  • Katarzyna Pietrucha,
  • Gabriela Górska,
  • Dagmara Kogut and
  • Olga Ciepiela

7 August 2023

(1) Background: The massive transfusion of packed red blood cells (RBCs) is a lifesaving procedure, but it is associated with complications, e.g., dysmagnesemia. Since magnesium is an intracellular ion, the transfused RBCs can significantly influence...

(This article belongs to the Section Hematology)
  • Feature Paper
  • Article
  • Open Access
4 Citations
5,006 Views
9 Pages

Three-Loop Technique for Pulley Reconstruction—A Retrospective Cohort Analysis of 23 Patients

  • Simon Oeckenpöhler,
  • Martin Franz Langer,
  • Matthias Michael Aitzetmüller-Klietz,
  • Marie-Luise Aitzetmüller-Klietz,
  • Valerie Nottberg and
  • Oliver Riesenbeck

7 August 2023

Twenty-three patients with a mean age of 52.7 years underwent pulley reconstruction using the Okutsu double- or triple-loop technique after iatrogenic or traumatic rupture of at least two adjacent flexor tendon pulleys in the finger and distal palm;...

(This article belongs to the Section Clinical Rehabilitation)
  • Article
  • Open Access
2 Citations
2,970 Views
12 Pages

Cyanoacrylate in Colorectal Surgery: Is It Safe?

  • Anna D’Amore,
  • Pietro Anoldo,
  • Michele Manigrasso,
  • Giovanni Aprea,
  • Giovanni Domenico De Palma and
  • Marco Milone

7 August 2023

Anastomotic leakage (AL) of a gastrointestinal (GI) anastomosis continues to be an important complication in GI surgery. Since its introduction more than 60 years ago, Cyanoacrylate (CA) has gained popularity in colorectal surgery to provide “p...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
3 Citations
3,413 Views
10 Pages

The Risk and Predictors of Malignancies in Ankylosing Spondylitis Patients in Israel—A Retrospective Electronic Data-Based Study

  • Polina Kagan,
  • Noy Horesh,
  • Howard Amital,
  • Avishai M. Tsur,
  • Abdulla Watad,
  • Arnon D. Cohen and
  • Niv Ben-Shabat

7 August 2023

Background: Previous studies demonstrated unclear and vast variability in the association between Ankylosing Spondylitis (AS) and the risk of cancer. Objectives: To assess the risk of overall and site-specific malignancies for AS patients in Israel,...

(This article belongs to the Section Immunology & Rheumatology)
  • Article
  • Open Access
10 Citations
3,328 Views
12 Pages

Implementation and Assessment of a Laparotomy-Assisted Three-Port Fetoscopic Spina Bifida Repair Program

  • Corinna Keil,
  • Siegmund Köhler,
  • Benjamin Sass,
  • Maximilian Schulze,
  • Gerald Kalmus,
  • Michael Belfort,
  • Nicolas Schmitt,
  • Daniele Diehl,
  • Alice King and
  • Ivonne Bedei
  • + 12 authors

7 August 2023

Open spina bifida (OSB) is a congenital, non-lethal malformation with multifactorial etiology. Fetal therapy can be offered under certain conditions to parents after accurate prenatal diagnostic and interdisciplinary counseling. Since the advent of p...

(This article belongs to the Special Issue Update on Prenatal Diagnosis and Maternal Fetal Medicine)
  • Article
  • Open Access
10 Citations
7,071 Views
10 Pages

Association of Helicobacter pylori Infection with Autoimmune Thyroid Disease in the Female Sex

  • Maria Pina Dore,
  • Giuseppe Fanciulli,
  • Alessandra Manca and
  • Giovanni Mario Pes

6 August 2023

Background. Helicobacter pylori infection has been associated with an increased risk of thyroid diseases (TDs), although scientific evidence is conflicting. In the present study the relationship between TDs, including both autoimmune (AI) and non-aut...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
13 Citations
3,789 Views
14 Pages

Relationship between Urinary Parameters and Double-J Stent Encrustation

  • Jose Luis Bauzá,
  • Paula Calvó,
  • Francesca Julià,
  • Jorge Guimerà,
  • Ana Isabel Martínez,
  • Antonio Tienza,
  • Antonia Costa-Bauzá,
  • Pilar Sanchís,
  • Félix Grases and
  • Enrique Pieras

6 August 2023

(1) Background: This study aimed to determine the relationship between metabolic urine conditions and the formation, severity, and composition of encrustations in ureteral stents. (2) Methods: Ninety stone-former patients requiring a double-J stent w...

(This article belongs to the Section Nephrology & Urology)
  • Perspective
  • Open Access
43 Citations
15,143 Views
23 Pages

6 August 2023

Depending on how severe it is, malocclusion, which may involve misaligned teeth, jaws, or a combination of the two, can hurt a person’s overall facial aesthetics. The maxillary molar develops before the mandibular molar in class II malocclusion...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
43 Citations
4,637 Views
12 Pages

Correlation between Inflammatory Systemic Biomarkers and Surgical Trauma in Elderly Patients with Hip Fractures

  • Flaviu Moldovan,
  • Adrian Dumitru Ivanescu,
  • Pal Fodor,
  • Liviu Moldovan and
  • Tiberiu Bataga

6 August 2023

The treatment for hip fractures consists of a wide variety of orthopedic implants ranging from prosthesis to intramedullary nails. The purpose of this study is to determine the correlation between blood-count-derived biomarkers such as the neutrophil...

(This article belongs to the Special Issue Risk Factors, Prevention and Management of Frailty in Elderly)
  • Feature Paper
  • Article
  • Open Access
3 Citations
2,207 Views
16 Pages

6 August 2023

Within this single-center cohort study, we investigated the impact of optimal medical therapy on all-cause mortality, major amputation-free survival and clinically driven target lesion revascularization (CD TLR) in 552 patients with peripheral arteri...

(This article belongs to the Section Vascular Medicine)
  • Article
  • Open Access
14 Citations
3,627 Views
12 Pages

Burnout and Professional Engagement during the COVID-19 Pandemic among Nursing Students without Clinical Experience: A Cross-Sectional Study

  • Gustavo R. Cañadas,
  • María José Membrive-Jiménez,
  • María Begoña Martos-Cabrera,
  • Luis Albendín-García,
  • Almudena Velando-Soriano,
  • Guillermo A. Cañadas-De la Fuente and
  • Emilia Inmaculada De la Fuente-Solana

6 August 2023

Burnout affects many healthcare professionals, especially nurses, causing serious health problems and disrupting the work environment. Academic burnout may also be experienced, leading students to feel unable to cope with their education. As a result...

(This article belongs to the Special Issue Psychotherapy and Clinical Psychology during COVID-19)
  • Article
  • Open Access
46 Citations
3,850 Views
8 Pages

Short-Term Outcomes of Faricimab Treatment in Aflibercept-Refractory Eyes with Neovascular Age-Related Macular Degeneration

  • Maya Kishi,
  • Akiko Miki,
  • Aya Kamimura,
  • Mina Okuda,
  • Wataru Matsumiya,
  • Hisanori Imai,
  • Sentaro Kusuhara and
  • Makoto Nakamura

6 August 2023

To evaluate the functional and anatomical effects of switching to faricimab for patients with neovascular age-related macular degeneration (nAMD) refractory to intravitreal aflibercept, this retrospective study evaluated patients with nAMD who receiv...

(This article belongs to the Special Issue Latest Advances in the Diagnosis and Management of Vitreo-Retinal Disorders)
  • Review
  • Open Access
34 Citations
4,581 Views
9 Pages

Use of Artificial Intelligence in the Advancement of Breast Surgery and Implications for Breast Reconstruction: A Narrative Review

  • Ishith Seth,
  • Gabriella Bulloch,
  • Konrad Joseph,
  • David J. Hunter-Smith and
  • Warren Matthew Rozen

6 August 2023

Background: Breast reconstruction is a pivotal part of the recuperation process following a mastectomy and aims to restore both the physical aesthetic and emotional well-being of breast cancer survivors. In recent years, artificial intelligence (AI)...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
30 Citations
5,326 Views
11 Pages

Global Epidemiology and Burden of Elderly-Onset Inflammatory Bowel Disease: A Decade in Review

  • Pojsakorn Danpanichkul,
  • Kanokphong Suparan,
  • Suchapa Arayakarnkul,
  • Aunchalee Jaroenlapnopparat,
  • Natchaya Polpichai,
  • Panisara Fangsaard,
  • Siwanart Kongarin,
  • Karan Srisurapanont,
  • Banthoon Sukphutanan and
  • Karn Wijarnpreecha
  • + 5 authors

6 August 2023

Inflammatory bowel disease (IBD), once thought to impact younger individuals, now manifests in approximately 10% of patients over 65, characterized by a heightened vulnerability to complications and greater diagnostic intricacies than conventional ca...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Review
  • Open Access
11 Citations
6,455 Views
14 Pages

Renal Perfusion, Oxygenation and Metabolism: The Role of Imaging

  • Johanna Päivärinta,
  • Ioanna A. Anastasiou,
  • Niina Koivuviita,
  • Kanishka Sharma,
  • Pirjo Nuutila,
  • Ele Ferrannini,
  • Anna Solini and
  • Eleni Rebelos

6 August 2023

Thanks to technical advances in the field of medical imaging, it is now possible to study key features of renal anatomy and physiology, but so far poorly explored due to the inherent difficulties in studying both the metabolism and vasculature of the...

(This article belongs to the Special Issue Recent Advances in Kidney Disease Imaging)
  • Article
  • Open Access
23 Citations
7,676 Views
13 Pages

The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study

  • Rossana Abud Cabrera Rosa,
  • João Victor Soares Rodrigues,
  • Marina Module Cláudio,
  • João Paulo Soares Franciscon,
  • Gabriel Mulinari-Santos,
  • Thamiris Cirelli,
  • Rafael Scaf de Molon,
  • Valdir Gouveia Garcia and
  • Leticia Helena Theodoro

5 August 2023

Recent evidence suggests an association between hypertension and periodontitis, although the pathways and implications underlying both chronic conditions are still poorly understood. Therefore, the aim of this study was to evaluate the relationship b...

(This article belongs to the Special Issue Innovative Research in Periodontology and Implantology)
  • Systematic Review
  • Open Access
11 Citations
9,362 Views
21 Pages

Influence of Physical Activity during Pregnancy on Type and Duration of Delivery, and Epidural Use: Systematic Review and Meta-Analysis

  • Dingfeng Zhang,
  • Stephanie-May Ruchat,
  • Cristina Silva-Jose,
  • Javier Gil-Ares,
  • Rubén Barakat and
  • Miguel Sánchez-Polán

5 August 2023

Cesarean delivery may increase the need for anesthesia administration, thereby causing potential risks to both maternal and fetal health. This article aimed to investigate the effect of physical activity during pregnancy on the type of delivery, the...

(This article belongs to the Section Obstetrics & Gynecology)
  • Feature Paper
  • Review
  • Open Access
115 Citations
31,020 Views
34 Pages

A Comprehensive Review on Neuroendocrine Neoplasms: Presentation, Pathophysiology and Management

  • Qamar Sultana,
  • Jill Kar,
  • Amogh Verma,
  • Shreya Sanghvi,
  • Nirja Kaka,
  • Neil Patel,
  • Yashendra Sethi,
  • Hitesh Chopra,
  • Mohammad Amjad Kamal and
  • Nigel H. Greig

5 August 2023

Neuroendocrine neoplasms (NENs) are a group of heterogeneous tumors with neuroendocrine differentiation that can arise from any organ. They account for 2% of all malignancies in the United States. A significant proportion of NEN patients experience e...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
4 Citations
2,767 Views
10 Pages

Predictive Factors for Decreasing Left Ventricular Ejection Fraction and Progression to the Dilated Phase of Hypertrophic Cardiomyopathy

  • Kakeru Ishihara,
  • Yoshiaki Kubota,
  • Junya Matsuda,
  • Yoichi Imori,
  • Yukichi Tokita,
  • Kuniya Asai and
  • Hitoshi Takano

5 August 2023

Patients with hypertrophic cardiomyopathy (HCM) may progress to the dilated phase (DHCM). This study aimed to identify the predictive factors for DHCM progression, including left ventricular (LV) ejection fraction (LVEF < 50%) or decreased LV cont...

(This article belongs to the Special Issue Cardiomyopathy: Clinical Diagnosis and Treatment)
  • Article
  • Open Access
7 Citations
2,269 Views
14 Pages

MRI and Pulmonary Function Tests’ Results as Ventilation Inhomogeneity Markers in Children and Adolescents with Cystic Fibrosis

  • Irena Wojsyk-Banaszak,
  • Barbara Więckowska,
  • Aleksandra Szczepankiewicz,
  • Zuzanna Stachowiak,
  • Marta Andrzejewska,
  • Jerzy Juchnowicz,
  • Maciej Kycler,
  • Paulina Famulska,
  • Marta Osińska and
  • Katarzyna Jończyk-Potoczna

5 August 2023

Magnetic resonance imaging (MRI) of the chest is becoming more available in the detection and monitoring of early changes in lung function and structure in patients with cystic fibrosis (CF). The aim of this study was to assess the relationship betwe...

(This article belongs to the Section Respiratory Medicine)
  • Feature Paper
  • Article
  • Open Access
2 Citations
2,764 Views
9 Pages

Prevalence of Accommodative Microfluctuations in Eyes after Cataract Surgery

  • Tomoko Kaida,
  • Takashi Ono,
  • Tadatoshi Tokunaga,
  • Keita Takada,
  • Shota Tokuda,
  • Naoto Kuwabara,
  • Takushi Kawamorita,
  • Kazutaka Kamiya,
  • Nobuyuki Shoji and
  • Kazunori Miyata

5 August 2023

Background: We aimed to evaluate the existence of accommodative microfluctuations in eyes after cataract surgery. Methods: This retrospective observational cohort study included 1160 eyes of 713 patients (mean age: 72.5 ± 8.3 years) who underw...

(This article belongs to the Section Ophthalmology)
  • Feature Paper
  • Article
  • Open Access
9 Citations
3,679 Views
13 Pages

A Japanese Prospective, Multicenter Study of Colonic Stenting for Palliation Using a High Axial Force Self-Expandable Metal Stent for Malignant Large Bowel Obstruction in 200 Patients

  • Rei Ishibashi,
  • Takashi Sasaki,
  • Hiroyuki Isayama,
  • Takeaki Matsuzawa,
  • Toshio Kuwai,
  • Tomonori Yamada,
  • Shuji Saito,
  • Masafumi Tomita,
  • Toshiyasu Shiratori and
  • Yoshihisa Saida
  • + 4 authors

5 August 2023

Evidence of the efficacy and safety of colorectal stent placement for palliation remains insufficient. This single-arm, prospective, multicenter study with a WallFlex enteral colonic stent included 200 consecutive patients with malignant large bowl o...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Feature Paper
  • Review
  • Open Access
23 Citations
12,166 Views
26 Pages

5 August 2023

In the context of autosomal dominant polycystic kidney disease (ADPKD), measurement of the total kidney volume (TKV) is crucial. It acts as a marker for tracking disease progression, and evaluating the effectiveness of treatment strategies. The TKV h...

(This article belongs to the Special Issue Recent Advances in Kidney Disease Imaging)
  • Review
  • Open Access
12 Citations
4,887 Views
25 Pages

5 August 2023

Advances in imaging techniques have led to a rise in the diagnosis of spontaneous cervicocranial arterial dissection (SCCAD), which is now considered a common cause of stroke in young adults. However, our understanding of the pathophysiological mecha...

(This article belongs to the Section Clinical Neurology)
  • Review
  • Open Access
27 Citations
6,281 Views
11 Pages

4 August 2023

Geographic atrophy (GA) affects around 5 million individuals worldwide. Genome-wide, histopathologic, in vitro and animal studies have implicated the activation of the complement system and chronic local inflammation in the pathogenesis of GA. Recent...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
6 Citations
3,221 Views
16 Pages

It Sounds like It Feels: Preliminary Exploration of an Aeroacoustic Diagnostic Protocol for Singers

  • Calvin Peter Baker,
  • Suzanne C. Purdy,
  • Te Oti Rakena and
  • Stefano Bonnini

4 August 2023

To date, no established protocol exists for measuring functional voice changes in singers with subclinical singing-voice complaints. Hence, these may go undiagnosed until they progress into greater severity. This exploratory study sought to (1) deter...

(This article belongs to the Special Issue New Advances in the Management of Voice Disorders)
  • Systematic Review
  • Open Access
19 Citations
4,035 Views
20 Pages

Telemedicine in Patients Affected by Chronic Liver Disease: A Scoping Review of Clinical Outcomes and the Devices Evaluated

  • Paolo Capuano,
  • Bethany Hileman,
  • Stefano Tigano,
  • Bianca Magro,
  • Vincenzina Lo Re,
  • Rosa Liotta,
  • Marco Sciveres,
  • Giusy Ranucci,
  • Alessio Provenzani and
  • Gennaro Martucci
  • + 3 authors

4 August 2023

For patients with chronic liver disease (CLD), telemedicine is emerging as a useful tool to prevent liver decompensation or hospitalization, allowing access to and the decentralization of care, even for patients with limited resources. However, resea...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
6 Citations
3,009 Views
14 Pages

Impact of the COVID-19 Pandemic on Productivity of Workers in the Health Sector between Working in a Hospital and from Home

  • Robert M. Trojak,
  • Melanie Lenger,
  • Armin Birner,
  • Alexander Maget,
  • Nina Dalkner,
  • Jorgos N. Lang,
  • Frederike T. Fellendorf,
  • Michaela Ratzenhofer,
  • Elena M. D. Schönthaler and
  • Eva Z. Reininghaus
  • + 5 authors

4 August 2023

Background: Due to the COVID-19 pandemic, workplaces in the medical field experienced changes. Non-frontline workers in the health sector (WHS) were in many cases allowed to work from home (WFH). Changes in work locations have affected the perception...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
14 Citations
3,811 Views
10 Pages

4 August 2023

Photobiomodulation is an effective treatment for pain. We previously reported that the direct laser irradiation of the exposed sciatic nerve inhibited firing in the rat spinal dorsal horn evoked by mechanical stimulation, corresponding to the noxious...

(This article belongs to the Topic Medical and Dental Care, Photobiomodulation and Photomedicine)
  • Article
  • Open Access
3 Citations
3,762 Views
13 Pages

Clinical Features and Outcomes of Acute Kidney Injury in Critically Ill COVID-19 Patients: A Retrospective Observational Study

  • Nabil Bouguezzi,
  • Imen Ben Saida,
  • Radhouane Toumi,
  • Khaoula Meddeb,
  • Emna Ennouri,
  • Amir Bedhiafi,
  • Dhouha Hamdi and
  • Mohamed Boussarsar

4 August 2023

Background: An alarming number of COVID-19 patients, especially in severe cases, have developed acute kidney injury (AKI). Aim: The study aimed to assess the frequency, risk factors, and impact of AKI on mortality in critically ill COVID-19 patients....

(This article belongs to the Section Intensive Care)
  • Article
  • Open Access
3 Citations
2,708 Views
15 Pages

Free-Hand MIS TLIF without 3D Navigation—How to Achieve Low Radiation Exposure for Both Surgeon and Patient

  • Roberto Doria-Medina,
  • Ulrich Hubbe,
  • Christoph Scholz,
  • Ronen Sircar,
  • Johannes Brönner,
  • Herbert Hoedlmoser and
  • Jan-Helge Klingler

4 August 2023

Background: Transforaminal lumbar interbody fusion (TLIF) is one of the most frequently performed spinal fusion techniques, and this minimally invasive (MIS) approach has advantages over the traditional open approach. A drawback is the higher radiati...

(This article belongs to the Special Issue Advances in Minimally Invasive Spine Surgery)
  • Article
  • Open Access
7 Citations
2,580 Views
14 Pages

Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass

  • Gisele Florêncio,
  • Aglécio Souza,
  • Elinton Chaim,
  • Allan Santos,
  • Louise Duran,
  • Camila Carvalho and
  • Sarah Monte Alegre

4 August 2023

Sarcopenic obesity is characterized by a disproportion between the amount of muscle to fat. Contrary to most studies evaluating parameters related to sarcopenic obesity in the elderly, this study aims to evaluate the phase angle (PhA) and sarcopenia...

(This article belongs to the Collection Obesity: From Diagnosis to Treatment)
  • Feature Paper
  • Article
  • Open Access
59 Citations
14,725 Views
17 Pages

4 August 2023

Chronic wounds (CWs) pose a significant health challenge in clinical practice. Standard wound therapy (SWT) is currently considered the gold standard. However, recent evidence suggests that cold plasma therapy (CPT) holds promise for improving CWs. I...

(This article belongs to the Special Issue Wound Healing and Plastic Surgery: Challenges and Innovations)
  • Article
  • Open Access
2 Citations
2,210 Views
16 Pages

Paraoxonase 1 Activity and Renal Replacement Therapy for Chronic Renal Failure: A Meta-Analysis

  • Jun Watanabe,
  • Kazuhiko Kotani,
  • Yoshitaka Iwazu and
  • Alejandro Gugliucci

4 August 2023

Chronic renal failure (CRF) is associated with the development of cardiovascular disease (CVD). Paraoxonase 1 (PON1), an antioxidant enzyme, shows cardioprotective properties and has been proposed as a therapeutic marker for CRF. A systematic analysi...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
3 Citations
1,843 Views
9 Pages

Medicare Advantage in Soft Tissue Sarcoma May Be Associated with Worse Patient Outcomes

  • Jennifer C. Wang,
  • Kevin C. Liu,
  • Brandon S. Gettleman,
  • Amit S. Piple,
  • Matthew S. Chen,
  • Lawrence R. Menendez,
  • Nathanael D. Heckmann and
  • Alexander B. Christ

4 August 2023

Medicare Advantage healthcare plans may present undue impediments that result in disparities in patient outcomes. This study aims to compare the outcomes of patients who underwent STS resection based on enrollment in either traditional Medicare (TM)...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
5 Citations
3,472 Views
13 Pages

4 August 2023

Training the respiratory muscles is a crucial aspect of pulmonary rehabilitation. The purpose of this study was to assess the function of respiratory muscles in older adults both before and after a period of pulmonary rehabilitation and treatment sta...

(This article belongs to the Section Respiratory Medicine)
  • Article
  • Open Access
12 Citations
6,945 Views
20 Pages

4 August 2023

Hemorrhoidal disease (HD) is a chronic multifactorial disease. Increased abdominal pressure, along with hyperperfusion, neovascularization, overexpression of inflammatory mediators, and dysbiosis, contributes to the development of HD. The deteriorati...

(This article belongs to the Special Issue Advances in Proctology and Colorectal Surgery)
  • Reply
  • Open Access
2 Citations
1,250 Views
3 Pages
  • Article
  • Open Access
5 Citations
2,389 Views
10 Pages

4 August 2023

The aim of this retrospective cross-sectional study was to comprehensively assess masticatory function in maxillectomy patients with functioning removable prostheses. Their general and oral profiles, the measurement values of their oral functions, in...

(This article belongs to the Special Issue State of the Art of Oral Health in Japan and Other Aging Countries)
  • Editorial
  • Open Access
2 Citations
1,762 Views
2 Pages

4 August 2023

Among patients admitted to medical wards, a growing number have various degrees of cardiac and renal dysfunction [...]

(This article belongs to the Special Issue New Insights into Cardio-Renal Interactions: Novel Definitions, Pathophysiology and Management)
  • Article
  • Open Access
4 Citations
4,375 Views
11 Pages

Development of a Cardiovascular Disease Risk Prediction Model: A Preliminary Retrospective Cohort Study of a Patient Sample in Saudi Arabia

  • Khaled Alabduljabbar,
  • Mohammed Alkhalifah,
  • Abdulaziz Aldheshe,
  • Abdulelah Bin Shihah,
  • Ahmed Abu-Zaid,
  • Edward B. DeVol,
  • Norah Albedah,
  • Haifa Aldakhil,
  • Balqees Alzayed and
  • Abdullah Alkhenizan
  • + 1 author

4 August 2023

Saudi Arabia has an alarmingly high incidence of cardiovascular disease (CVD) and its associated risk factors. To effectively assess CVD risk, it is essential to develop tailored models for diverse regions and ethnicities using local population varia...

(This article belongs to the Section Cardiovascular Medicine)

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J. Clin. Med. - ISSN 2077-0383