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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neuroendocrine Tumors: Challenges and Future Perspectives (Second Edition)

edited by

Anna La Salvia

and

Giuseppe Lamberti

submission deadline 5 Jul 2025 | 4 articles | Viewed by 3932 | Submission Open

Keywords: neuroendocrine tumors; clinical challenges; innovative biomarkers; novel agents; personalized oncology

(This special issue belongs to the Section Oncology)

Selected Papers from the 2nd International Electronic Conference on Clinical Medicine

edited by

Emmanuel Andrès

and

Kent Doi

submission deadline 5 Jul 2025 | Viewed by 543 | Submission Open

Keywords: cardiology; gastroenterology & hepatopancreatobiliary medicine; epidemiology & public health; AI & telemedicine; immunology; mental health; oncology & hematology; dermatology

Skin Cancer: Prevention, Diagnosis and Treatment

edited by Athanassios A. Kyrgidis and

Aimilios Lallas

submission deadline 10 Jul 2025 | 5 articles | Viewed by 12470 | Submission Open

Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life

(This special issue belongs to the Section Dermatology)

Heart Disease and Chronic Inflammatory Conditions: New Insights

edited by Ofer Kobo and Gilad Margolis

submission deadline 10 Jul 2025 | 4 articles | Viewed by 6693 | Submission Open

Keywords: heart diseases; chronic inflammatory; rheumatoid arthritis; cardiovascular disease; inflammatory bowel disease

(This special issue belongs to the Section Cardiology)

New Insights into Abdominal Surgery

edited by Pietro Fransvea

submission deadline 10 Jul 2025 | 2 articles | Viewed by 2851 | Submission Open

Keywords: acute care surgery; trauma; minimally invasive emergency surgery; artificial intelligence; outcome prediction

(This special issue belongs to the Section General Surgery)

Current and Emerging Therapies for Rheumatoid Arthritis

edited by

Yoshiro Horai

submission deadline 10 Jul 2025 | 1 articles | Viewed by 1847 | Submission Open

Keywords: DMARDs (disease-modifying anti-rheumatic drugs); boDMARDs (biological DMARDs); bsDMARDs (biosimilar DMARDs); csDMARDs (conventional synthetic DMARDs); rheumatoid arthritis; tsDMARDs (targeted synthetic DMARDs)

(This special issue belongs to the Section Immunology)

Clinical Therapeutic Advances in Bone Fractures

edited by Simon Hackl and Eva Simone Steinhausen

submission deadline 10 Jul 2025 | 1 articles | Viewed by 1354 | Submission Open

Keywords: stem cells; biomechanics; fracture fixation; orthobiologics; rehabilitation; personalized medicine; 3D printing; im-plant coating; nonunion; fracture-related infection

(This special issue belongs to the Section Orthopedics)

Heart Failure and Coronary Artery Diseases: Cardiovascular Complications and Comorbidities

edited by

Dhrubajyoti Bandyopadhyay

Vikash Jaiswal

and

Adrija Hajra

submission deadline 10 Jul 2025 | 1 articles | Viewed by 912 | Submission Open

Keywords: heart failure; acute myocardial infarction; coronary artery diseases; cardiac imaging; biomarkers; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Recent Advances and Challenges in Cardiothoracic Surgery

edited by Marco Anile and Vannucci Jacopo

submission deadline 10 Jul 2025 | Viewed by 514 | Submission Open

Keywords: minimally invasive thoracic surgery; RATS; uniportal VATS; lung transplantation; VATS for arrhythmias; new technologies; radiomics; STAS

(This special issue belongs to the Section Cardiology)

Advances in Burn Management

edited by Juan P. Barret

submission deadline 15 Jul 2025 | 6 articles | Viewed by 8512 | Submission Open

Keywords: burns; wound healing; immune response; stem cells ; burn surgery ; rehabilitation ; PROMs; PREMs

(This special issue belongs to the Section General Surgery)

Cardiac Imaging: Current Applications and Future Perspectives

edited by Anna Baritussio and Isabella Leo

submission deadline 15 Jul 2025 | 7 articles | Viewed by 7331 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac CT; cardiac MRI; nuclear imaging; artificial intelligence

(This special issue belongs to the Section Cardiology)

Clinical Application of Biomarkers in Cancers

edited by

Monica Florescu

submission deadline 15 Jul 2025 | 3 articles | Viewed by 4996 | Submission Open

Keywords: cancer biomarkers; early detection; personalized therapy; biomarker validation; advanced technologies; clinical implementation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Rheumatology: From Bench to Bedside

edited by

Matteo Colina

submission deadline 15 Jul 2025 | 2 articles | Viewed by 2934 | Submission Open

Keywords: autoimmune disease; inflammation pathophysiology; novel therapeutic strategies; translational medicine; bench to bedside (B2B); disease biomarkers

(This special issue belongs to the Section Immunology)

Peripheral Nerves: Imaging, Electrophysiology and Surgical Techniques

edited by

Raffaele Natella

, Aniello Iovino and Vito Stifano

submission deadline 15 Jul 2025 | 2 articles | Viewed by 2193 | Submission Open

Keywords: MRI; MSK imaging; soft-tissue tumors; DTI; neuropathies; inflammatory neuropathies; nerve entrapment; motor neuron disease; neurophysiology; MSK ultrasound; peripheral nerve tumor; nerve entrapment; nerve reconstruction

(This special issue belongs to the Section Clinical Neurology)

Current Trends and Prospects of Critical Emergency Medicine

edited by Quincy K. Tran

submission deadline 15 Jul 2025 | 2 articles | Viewed by 852 | Submission Open

Keywords: critically ill patients; critical care; resuscitation; emergency medicine; trends; prospects; outcomes

(This special issue belongs to the Section Emergency Medicine)

Pulmonary Embolism—Current and Novel Approaches

edited by Roy Beigel and Shlomi Matetzky

submission deadline 15 Jul 2025 | 1 articles | Viewed by 662 | Submission Open

Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification

(This special issue belongs to the Section Respiratory Medicine)

Pediatric Urology: How to Adapt Current Knowledge to the New Era

edited by Simona Gerocarni Nappo and

Elisa Cerchia

submission deadline 15 Jul 2025 | Viewed by 262 | Submission Open

Keywords: pediatric urology; telemedicine; telesurgery; artificial intelligence; 3D-models; congenital urinary diseases; pediatric oncology

(This special issue belongs to the Section Clinical Pediatrics)

Medicine and Exercise for Wellbeing: Effective Diagnosis and Non-Pharmacological Treatment in Chronic Conditions and Pain

edited by

Pedro Miguel Forte

submission deadline 16 Jul 2025 | 3 articles | Viewed by 3456 | Submission Open

Keywords: chronic pain; physical exercise; diagnosis; chronic conditions; pain management

(This special issue belongs to the Section Sports Medicine)

Keratoconus: Current Status and Prospects

edited by

Uxía Regueiro

and Isabel Lema

submission deadline 16 Jul 2025 | 3 articles | Viewed by 1813 | Submission Open

Keywords: keratoconus; prevention; diagnostic; biomarker discovery; genetics; exposome; treatment; personalized medicine; major challenges; technological advances

(This special issue belongs to the Section Ophthalmology)

New Insights into Acute Care and Emergency Surgery

edited by Jacob Chen and Avi Benov

submission deadline 17 Jul 2025 | 6 articles | Viewed by 9728 | Submission Open

Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU

(This special issue belongs to the Section General Surgery)

Stress, Rhythms Dysregulation and Bipolar Spectrum

edited by

Mauro Giovanni Carta

and

Giulia Cossu

submission deadline 20 Jul 2025 | 15 articles | Viewed by 25373 | Submission Open

Keywords: bipolar spectrum; neo-Kraepelinian tradition; dimensional approach; social rhythms; chronobiological rhythms

(This special issue belongs to the Section Mental Health)

Clinical Updates in Physiotherapy for Musculoskeletal Disorders

edited by

Santiago Navarro Ledesma

submission deadline 20 Jul 2025 | 6 articles | Viewed by 8008 | Submission Open

Keywords: musculoskeletal disorders; physiotherapy interventions; lifestyle; psychoneuroimmunology; chronic pain; inflammation; physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6167 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting

edited by Federico Raveglia,

Carmelina C. Zirafa

and

Mohsen Ibrahim

submission deadline 20 Jul 2025 | 6 articles | Viewed by 5943 | Submission Open

Keywords: lung cancer; interventional endoscopy; upper airway reconstruction; robotic diagnosis; robotic surgery

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Surgical Management of Gynecological Malignancies

edited by Laurentiu Pirtea and Răzvan Ştefan Ilina

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5198 | Submission Open

Keywords: minimally invasive surgery; laparoscopy surgery; robotic-assisted surgery; gynecological malignancies

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Cardiac Imaging

edited by

Łukasz A. Małek

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4391 | Submission Open

Keywords: non-invasive imaging; heart; vessels; application; diagnosis; technique

(This special issue belongs to the Section Cardiology)

Clinical Diagnosis and Management of Neonatal Diseases

edited by Ayala Gover and

Arieh Riskin

submission deadline 20 Jul 2025 | 6 articles | Viewed by 2910 | Submission Open

Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring

(This special issue belongs to the Section Clinical Pediatrics)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1889 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Hypertension and Related Complications

edited by

Thenral Socrates

and

Thilo Burkard

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1798 | Submission Open

Keywords: hypertension; hypertensive disorders of pregnancy; antihypertensive therapy; resistant hypertension; dual endothelin receptor antagonist; renal denervation; cardiovascular risk; adherence; kidney disease; secondary hypertension

(This special issue belongs to the Section Cardiovascular Medicine)

Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management

edited by Mariana Tudoran and

Cristina Tudoran

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1371 | Submission Open

Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID

(This special issue belongs to the Section Cardiovascular Medicine)

Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke

edited by

Fusao Ikawa

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1061 | Submission Open

Keywords: acute ischemic stroke; endovascular treatment; imaging; management of ischemic stroke; system and strategy for acute ischemic stroke; multidisciplinary approach for acute ischemic stroke

(This special issue belongs to the Section Clinical Neurology)

Advances in Tuberculosis: Comprehensive Insights and Management Strategies

edited by Aliaksandr Skrahin

submission deadline 20 Jul 2025 | 1 articles | Viewed by 872 | Submission Open

Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations

(This special issue belongs to the Section Infectious Diseases)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jul 2025 | 1 articles | Viewed by 726 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

Clinical Comparisons of Nonpharmaceutical and Pharmaceutical Analgesia

edited by

Sang Hun Kim

and

Yoon Ji Choi

submission deadline 20 Jul 2025 | Viewed by 228 | Submission Open

Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical

(This special issue belongs to the Section Anesthesiology)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 23 Jul 2025 | Viewed by 314 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Future Trends in the Diagnosis and Management of Celiac Disease

edited by

Carolina Ciacci

and

Antonella Santonicola

submission deadline 24 Jul 2025 | 3 articles | Viewed by 4729 | Submission Open

Keywords: celiac disease; gluten; autoimmune disease; extraintestinal manifestations; serologic diagnosis; gluten-free diet

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Artificial Intelligence (AI)-Based Diagnosis in Clinical Practice

edited by

Takao Fujisawa

submission deadline 24 Jul 2025 | 3 articles | Viewed by 4268 | Submission Open

Keywords: artificial intelligence; AI; diagnosis; clinical medicine; practice

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Treatment of Refractory Full Thickness Macular Hole (FTMH)

edited by

Rino Frisina

submission deadline 24 Jul 2025 | 1 articles | Viewed by 666 | Submission Open

Keywords: refractory full thickness macular hole; pars plana vittectomy; internal limiting membrane; peeling; tamponade; flap

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Maternal Fetal Medicine

edited by

Misgav Rottenstreich

and

Roberta Granese

submission deadline 25 Jul 2025 | 8 articles | Viewed by 16421 | Submission Open

Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecological Surgery: New Clinical Insights and Challenges

edited by Francesco Plotti

submission deadline 25 Jul 2025 | 9 articles | Viewed by 11332 | Submission Open

Keywords: minimally invasive surgery; urogynecologic surgery; complications; gynecologic oncology; robotic surgery; benign gynecologic surgery; vaginal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Debates in Minimally Invasive Glaucoma Surgery (MIGS)

edited by

Etsuo Chihara

submission deadline 25 Jul 2025 | 9 articles | Viewed by 9194 | Submission Open

Keywords: MIGS (minimally invasive glaucoma surgery); schlemm’ s canal opening surgery; trabeculotomy; trabeculectomy; collector channel; histology; intraocular pressure; surgical success

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in Hemodialysis

edited by Maurizio Bossola

submission deadline 25 Jul 2025 | 7 articles | Viewed by 7075 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives in Trauma and Orthopedic Surgery

edited by

Francesca Veronesi

submission deadline 25 Jul 2025 | 4 articles | Viewed by 5085 | Submission Open

Keywords: trauma; sports; ankle; knee; hip; cartilage regeneration; bone regeneration; orthopedic surgery

(This special issue belongs to the Section Orthopedics)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 25 Jul 2025 | 5 articles | Viewed by 4651 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Thoracic Imaging in Cardiovascular and Pulmonary Disease Diagnosis

edited by Marco Sperandeo and

Carla Maria Irene Quarato

submission deadline 25 Jul 2025 | 3 articles | Viewed by 4573 | Submission Open

Keywords: thoracic imaging; cardiovascular diagnosis; pulmonary disease; clinical medicine; diagnostic accuracy; imaging techniques; thoracic ultrasound; patient care

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Foot and Ankle Surgery: State of the Art and Future Perspectives

edited by Sung Jae Kim and Jaehwang Song

submission deadline 25 Jul 2025 | 5 articles | Viewed by 3744 | Submission Open

Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 25 Jul 2025 | 1 articles | Viewed by 2990 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Multiple Myeloma: Advances in Diagnosis and Treatment

edited by

Martina Kleber

submission deadline 25 Jul 2025 | 2 articles | Viewed by 2636 | Submission Open

Keywords: multiple myeloma; early intervention; novel therapies; treatment approach; prognosis; bispecific antibodies; CAR T-cells

(This special issue belongs to the Section Oncology)

Vasculitis in Adults and Children: Symptoms, Diagnosis and Treatment—2nd Edition

edited by

Ryu Watanabe

submission deadline 25 Jul 2025 | 1 articles | Viewed by 1970 | Submission Open

Keywords: vasculitis; glucocorticoids; cyclophosphamide; molecularly targeted therapy; unmet clinical needs; potential therapeutic targets

(This special issue belongs to the Section Vascular Medicine)

Innovative Clinical Approaches in Oral Health Prevention and Management

edited by

Giulia Orilisi

Rossana Izzetti

and Flavia Vitiello

submission deadline 25 Jul 2025 | 2 articles | Viewed by 1858 | Submission Open

Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

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