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Biosensors, Volume 11, Issue 1

2021 January - 26 articles

Cover Story: Dithiocarbamate fungicides (DTFs) are widely used to control various fungal diseases in crops and ornamental plants. Maximum residue limits in the order of ppb–ppm are imposed by the current legislation. The specific analytical determination of DTFs is complicated by their low solubility in water and organic solvents. This review summarizes the current analytical procedures used for the analysis of DTF, including chromatography, spectroscopy, and sensor-based methods, and discusses the challenges related to selectivity, sensitivity, and sample preparation. Biosensors based on enzymatic inhibition demonstrated potential as analytical tools for DTFs. Meanwhile, recent studies highlight Raman spectroscopy and various sensors as very promising, provided their selectivity issues are solved. View this paper.
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Articles (26)

  • Article
  • Open Access
27 Citations
6,875 Views
17 Pages

Quantitative E. coli Enzyme Detection in Reporter Hydrogel-Coated Paper Using a Smartphone Camera

  • Kawaljit Kaur,
  • Winny Chelangat,
  • Sergey I. Druzhinin,
  • Nancy Wangechi Karuri,
  • Mareike Müller and
  • Holger Schönherr

19 January 2021

There is a growing demand for rapid and sensitive detection approaches for pathogenic bacteria that can be applied by non-specialists in non-laboratory field settings. Here, the detection of the typical E. coli enzyme β-glucuronidase using a chi...

(This article belongs to the Section Biosensor Materials)
  • Review
  • Open Access
33 Citations
10,855 Views
16 Pages

19 January 2021

The ketogenic diet, while originally thought to treat epilepsy in children, is now used for weight loss due to increasing evidence indicating that fat is burned more rapidly when there is a low carbohydrate intake. This low carbohydrate intake can le...

(This article belongs to the Special Issue Non-invasive Medical Devices for Detection and Monitoring within Healthcare)
  • Article
  • Open Access
35 Citations
10,035 Views
15 Pages

Influence of the Electrolyte Salt Concentration on DNA Detection with Graphene Transistors

  • Agnes Purwidyantri,
  • Telma Domingues,
  • Jérôme Borme,
  • Joana Rafaela Guerreiro,
  • Andrey Ipatov,
  • Catarina M. Abreu,
  • Marco Martins,
  • Pedro Alpuim and
  • Marta Prado

17 January 2021

Liquid-gated Graphene Field-Effect Transistors (GFET) are ultrasensitive bio-detection platforms carrying out the graphene’s exceptional intrinsic functionalities. Buffer and dilution factor are prevalent strategies towards the optimum performa...

(This article belongs to the Special Issue Field-Effect Transistors for Biosensing Applications)
  • Letter
  • Open Access
13 Citations
4,318 Views
11 Pages

16 January 2021

In this paper, we developed an isolation system for A549 human lung carcinoma cells as an effective factor for the early diagnosis of lung cancer. A microfluidic immunomagnetic method was used, in which the combination of immunomagnetic separation an...

(This article belongs to the Section Biosensors and Healthcare)
  • Article
  • Open Access
37 Citations
5,095 Views
14 Pages

15 January 2021

In this study, we designed a simple, rapid, sensitive and selective surface plasmon resonance (SPR) sensor for detection of L-phenylalaine by utilizing molecular imprinting technology. l-phenylalanine imprinted and non-imprinted poly(2-hydroxyethyl m...

  • Brief Report
  • Open Access
6 Citations
4,170 Views
7 Pages

Performance of the Intermittently Scanned Continuous Glucose Monitoring (isCGM) System during a High Oral Glucose Challenge in Adults with Type 1 Diabetes—A Prospective Secondary Outcome Analysis

  • Othmar Moser,
  • Norbert Tripolt,
  • Peter Pferschy,
  • Anna Obermayer,
  • Harald Kojzar,
  • Alexander Mueller,
  • Hakan Yildirim,
  • Caren Sourij,
  • Max Eckstein and
  • Harald Sourij

15 January 2021

To assess intermittently scanned continuous glucose monitoring (isCGM) performance for different rates of change in plasma glucose (RCPG) during glycemic challenges in type 1 diabetes (T1D). Nineteen people with T1D (7 females; age 35 ± 11 yea...

(This article belongs to the Section Biosensors and Healthcare)
  • Article
  • Open Access
24 Citations
6,411 Views
15 Pages

Kynurenic Acid Electrochemical Immunosensor: Blood-Based Diagnosis of Alzheimer’s Disease

  • Jose Marrugo-Ramírez,
  • Montserrat Rodríguez-Núñez,
  • M.-Pilar Marco,
  • Mónica Mir and
  • Josep Samitier

12 January 2021

Alzheimer’s disease (AD) is a neurodegenerative disorder, characterized by a functional deterioration of the brain. Currently, there are selected biomarkers for its diagnosis in cerebrospinal fluid. However, its extraction has several disadvantages f...

(This article belongs to the Section Biosensors and Healthcare)
  • Article
  • Open Access
10 Citations
5,118 Views
10 Pages

11 January 2021

Hypoxanthine (hpx) is an important molecule for both biochemistry research and biomedical applications. It is involved in several biological processes associated to energy and purine metabolism and has been proposed as a biomarker for a variety of di...

(This article belongs to the Section Biosensor and Bioelectronic Devices)
  • Communication
  • Open Access
15 Citations
8,990 Views
12 Pages

Detection of CRISPR-Cas9-Mediated Mutations Using a Carbon Nanotube-Modified Electrochemical Genosensor

  • Ezgi Kivrak,
  • Tekle Pauzaite,
  • Nikki A. Copeland,
  • John G. Hardy,
  • Pinar Kara,
  • Melike Firlak,
  • Atike I. Yardimci,
  • Selahattin Yilmaz,
  • Fahreddin Palaz and
  • Mehmet Ozsoz

8 January 2021

The CRISPR-Cas9 system has facilitated the genetic modification of various model organisms and cell lines. The outcomes of any CRISPR-Cas9 assay should be investigated to ensure/improve the precision of genome engineering. In this study, carbon nanot...

(This article belongs to the Special Issue Application of CRISPR Cas Systems for Biosensing)
  • Article
  • Open Access
28 Citations
7,283 Views
18 Pages

Aptamer–Target–Gold Nanoparticle Conjugates for the Quantification of Fumonisin B1

  • Vicente Antonio Mirón-Mérida,
  • Yadira González-Espinosa,
  • Mar Collado-González,
  • Yun Yun Gong,
  • Yuan Guo and
  • Francisco M. Goycoolea

8 January 2021

Fumonisin B1 (FB1), a mycotoxin classified as group 2B hazard, is of high importance due to its abundance and occurrence in varied crops. Conventional methods for detection are sensitive and selective; however, they also convey disadvantages such as...

(This article belongs to the Special Issue Selected Papers from the 1st International Electronic Conference on Biosensors (IECB 2020))
  • Article
  • Open Access
68 Citations
13,480 Views
12 Pages

Development of a Sensitive Self-Powered Glucose Biosensor Based on an Enzymatic Biofuel Cell

  • Kantapat Chansaenpak,
  • Anyanee Kamkaew,
  • Sireerat Lisnund,
  • Pannaporn Prachai,
  • Patipat Ratwirunkit,
  • Thitichaya Jingpho,
  • Vincent Blay and
  • Piyanut Pinyou

7 January 2021

Biofuel cells allow for constructing sensors that leverage the specificity of enzymes without the need for an external power source. In this work, we design a self-powered glucose sensor based on a biofuel cell. The redox enzymes glucose dehydrogenas...

(This article belongs to the Special Issue Electrochemical Biosensors)
  • Article
  • Open Access
27 Citations
4,387 Views
15 Pages

An Electrochemical Strategy for the Simultaneous Detection of Doxorubicin and Simvastatin for Their Potential Use in the Treatment of Cancer

  • Iulia Rus,
  • Mihaela Tertiș,
  • Cristina Barbălată,
  • Alina Porfire,
  • Ioan Tomuță,
  • Robert Săndulescu and
  • Cecilia Cristea

3 January 2021

The aim of this study was to develop a disposable, simple, fast, and sensitive sensor for the simultaneous electrochemical detection of doxorubicin (DOX) and simvastatin (SMV), which could be used in preclinical studies for the development of new pha...

(This article belongs to the Special Issue Electrochemical Biosensors)
  • Review
  • Open Access
32 Citations
16,646 Views
32 Pages

Survey of Saliva Components and Virus Sensors for Prevention of COVID-19 and Infectious Diseases

  • Priya Kishor Dave,
  • Roberto Rojas-Cessa,
  • Ziqian Dong and
  • Vatcharapan Umpaichitra

31 December 2020

The United States Centers for Disease Control and Prevention considers saliva contact the lead transmission mean of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19). Saliva droplets or...

(This article belongs to the Section Biosensor and Bioelectronic Devices)
  • Review
  • Open Access
50 Citations
9,090 Views
26 Pages

Advances in the Detection of Dithiocarbamate Fungicides: Opportunities for Biosensors

  • Pablo Fanjul-Bolado,
  • Ronen Fogel,
  • Janice Limson,
  • Cristina Purcarea and
  • Alina Vasilescu

30 December 2020

Dithiocarbamate fungicides (DTFs) are widely used to control various fungal diseases in crops and ornamental plants. Maximum residual limits in the order of ppb-ppm are currently imposed by legislation to prevent toxicity problems associated with exc...

(This article belongs to the Special Issue Biosensors: 10th Anniversary Feature Papers)
  • Article
  • Open Access
24 Citations
5,527 Views
12 Pages

30 December 2020

High levels of blood glucose are always associated with numerous complications including cholesterol abnormalities. Therefore, it is important to simultaneously monitor blood glucose and cholesterol levels in patients with diabetes during the managem...

(This article belongs to the Special Issue Biosensors for Diagnosis and Monitoring)
  • Article
  • Open Access
23 Citations
6,515 Views
14 Pages

28 December 2020

Potentiometric redox sensing is a relatively inexpensive and passive approach to evaluate the overall redox state of complex biological and environmental solutions. The ability to make such measurements in ultra-small volumes using high surface area,...

(This article belongs to the Section Biosensor and Bioelectronic Devices)
  • Review
  • Open Access
61 Citations
11,065 Views
31 Pages

Solid State Sensors for Hydrogen Peroxide Detection

  • Vinay Patel,
  • Peter Kruse and
  • Ponnambalam Ravi Selvaganapathy

25 December 2020

Hydrogen peroxide (H2O2) is a key molecule in numerous physiological, industrial, and environmental processes. H2O2 is monitored using various methods like colorimetry, luminescence, fluorescence, and electrochemical methods. Here, we aim to provide...

(This article belongs to the Section Nano- and Micro-Technologies in Biosensors)
  • Article
  • Open Access
32 Citations
4,974 Views
13 Pages

24 December 2020

Facile detection methods for mycotoxins with high sensitivity are of great significance to prevent potential harm to humans. Herein, a label-free amperometric immunosensor based on a 3-D interconnected carbon nanofibers (CNFs) network coupled with we...

(This article belongs to the Section Biosensor Materials)
  • Article
  • Open Access
21 Citations
8,045 Views
9 Pages

24 December 2020

Leptin is a peptide hormone produced primarily in adipose tissues. Leptin is considered a biomarker associated with obesity and obesity-mediated diseases. Biosensor detection of leptin in the blood may play a critical role as an indicator of dynamic...

(This article belongs to the Section Biosensors and Healthcare)
  • Article
  • Open Access
15 Citations
4,353 Views
13 Pages

Fluorescent Probe for Ag+ Detection Using SYBR GREEN I and C-C Mismatch

  • Xiaohong Zhou,
  • Abdul Ghaffar Memon,
  • Weiming Sun,
  • Fang Fang and
  • Jinsong Guo

24 December 2020

Among heavy metals silver ions (Ag+) severely impact water, the environment and have serious side effects on human health. This article proposes a facile and ultrasensitive fluorescent probe for the detection of Ag+ ions using SYBR Green I (SGI) and...

(This article belongs to the Special Issue Last Advances in Optical Biosensors)
  • Article
  • Open Access
24 Citations
6,879 Views
13 Pages

Development of Fluorescence In Situ Hybridization as a Rapid, Accurate Method for Detecting Coliforms in Water Samples

  • Jong-Tar Kuo,
  • Li-Li Chang,
  • Chia-Yuan Yen,
  • Teh-Hua Tsai,
  • Yu-Chi Chang,
  • Yu-Tang Huang and
  • Ying-Chien Chung

24 December 2020

Coliform bacteria are indicators of water quality; however, most detection methods for coliform bacteria are time-consuming and nonspecific. Here, we developed a fluorescence in situ hybridization (FISH) approach to detect four types of coliform bact...

(This article belongs to the Section Biosensor and Bioelectronic Devices)
  • Article
  • Open Access
15 Citations
4,884 Views
13 Pages

24 December 2020

An optical cavity-based biosensor (OCB) has been developed for point-of-care (POC) applications. This label-free biosensor employs low-cost components and simple fabrication processes to lower the overall cost while achieving high sensitivity using a...

(This article belongs to the Special Issue Photonic Biosensors: Detection, Analysis and Medical Diagnostics)
  • Article
  • Open Access
7 Citations
3,969 Views
18 Pages

A Label-Free Optical Detection of Pathogens in Isopropanol as a First Step towards Real-Time Infection Prevention

  • Julie Claudinon,
  • Siegfried Steltenkamp,
  • Manuel Fink,
  • Taras Sych,
  • Benoît Verreman,
  • Winfried Römer and
  • Morgan Madec

23 December 2020

The detection of pathogens is a major public health issue. Every year, thousands of people die because of nosocomial infections. It is therefore important to be able to detect possible outbreaks as early as possible, especially in the hospital enviro...

(This article belongs to the Section Intelligent Biosensors and Bio-Signal Processing)
  • Article
  • Open Access
59 Citations
7,605 Views
18 Pages

23 December 2020

Herein we report the electropolymerization of a scopoletin based molecularly imprinted polymer (MIP) for the detection of lysozyme (Lyz), an enzymatic marker of several diseases in mammalian species. Two different approaches have been used for the im...

(This article belongs to the Section Biosensor Materials)
  • Article
  • Open Access
35 Citations
5,624 Views
10 Pages

An Electrochemical Aptasensor for Pb2+ Detection Based on Metal–Organic-Framework-Derived Hybrid Carbon

  • Jina Ding,
  • Dongwei Zhang,
  • Yang Liu,
  • Xuejia Zhan,
  • Yitong Lu,
  • Pei Zhou and
  • Dan Zhang

22 December 2020

A new double-shelled carbon nanocages material was synthesized and developed an aptasensor for determining Pb2+ in aqueous solution. Herein, nanoporous carbon materials derived from core–shell zeolitic imidazolate frameworks (ZIFs) demonstrated excel...

(This article belongs to the Special Issue New Developments for Efficient Rapid Bioassays)
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Biosensors - ISSN 2079-6374