Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions
Abstract
:1. Introduction
2. Results and Discussion
Entry | Solvent system | [cloxiquine] gel stability |
---|---|---|
1 | 1:1 EtOH/H2O | 1.0% very stable |
2 | 1:1 EtOH/H2O | 0.75% stable |
3 | 1:1 EtOH/H2O | 0.5% stable |
4 | 1:2 EtOH/H2O | 1.0% stable |
5 | 1:2 EtOH/H2O | 0.5% stable |
6 | 1:2 EtOH/H2O | 0.2% poor |
7 | 1:4 EtOH/H2O | 1.0% stable |
8 | 2:1 MeOH/H2O | 1.0% very stable |
9 | 2:1 MeOH/H2O | 0.75% stable |
10 | 2:1 MeOH/H2O | 0.5% precipitate |
11 | 1:2 MeOH/H2O | 1.0% precipitate |
12 | 1:4 MeOH/H2O | 1.0% precipitate |
13 | 2:1 1-PrOH/H2O | 1.0% precipitate |
14 | 1:1 1-PrOH/H2O | 2.0% very stable |
15 | 1:1 1-PrOH/H2O | 1.0% stable |
16 | 1:1 1-PrOH/H2O | 0.75% poor |
17 | 1:1 1-PrOH/H2O | 0.5% precipitate |
18 | 1:2 1-PrOH/H2O | 1.0% stable |
19 | 1:4 1-PrOH/H2O | 1.0% stable |
20 | 1:4 1-PrOH/H2O | 0,5% stable |
21 | 1:4 1-PrOH/H2O | 0.2% stable |
22 | 1:4 1-PrOH/H2O | 0.1% stable |
23 | 1:8 1-PrOH/H2O | 1.0% precipitate |
24 | 1:10 1-PrOH/H2O | 1.0% precipitate |
25 | 1:1 2-PrOH/H2O | 2.0% stable |
26 | 1:1 2-PrOH/H2O | 1.0% stable |
27 | 1:1 2-PrOH/H2O | 0.5% stable |
28 | 1:1 2-PrOH/H2O | 0.2% poor |
29 | 1:2 2-PrOH/H2O | 1% (g) stable |
30 | 1:4 2-PrOH/H2O | 1% precipitate |
3. Experimental
4. Conclusions
Acknowledgments
Conflict of Interest
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Kolehmainen, E.; Salo, H.; Korpela, J. Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions. Antibiotics 2012, 1, 17-24. https://doi.org/10.3390/antibiotics1010017
Kolehmainen E, Salo H, Korpela J. Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions. Antibiotics. 2012; 1(1):17-24. https://doi.org/10.3390/antibiotics1010017
Chicago/Turabian StyleKolehmainen, Erkki, Hannu Salo, and Jukka Korpela. 2012. "Gelation Behavior of 5-Chloro-8-hydroxyquinoline, an Antituberculosis Agent in Aqueous Alcohol Solutions" Antibiotics 1, no. 1: 17-24. https://doi.org/10.3390/antibiotics1010017