Periodontal Microbiological Status Influences the Occurrence of Cyclosporine-A and Tacrolimus-Induced Gingival Overgrowth
Abstract
:1. Background
2. Materials and Methods
3. Statistical Analysis
4. Results
5. Discussion
6. Conclusions
Author Contributions
Finding
Conflicts of Interest
References
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Statistic Tests a | ||||
---|---|---|---|---|
Periodontal Indices | U of Mann-Whitney | W of Wilcoxon | Z | Asymptotic Sign. (with Two Tails) |
PI T0 | 269,500 | 675,500 | −994 | 0.320 |
PI T1 | 269,500 | 675,500 | −996 | 0.319 |
PI T2 | 165,500 | 571,500 | −2974 | 0.003 |
PI T3 | 189,000 | 595,000 | −2528 | 0.011 |
GI T0 | 230,000 | 636,000 | −1742 | 0.081 |
GI T1 | 235,000 | 641,000 | −1649 | 0.099 |
GIT2 | 184,500 | 590,500 | −2616 | 0.009 |
GI T3 | 133,000 | 539,000 | −3597 | 0.000 |
GO T0 | 250,000 | 656,000 | −1744 | 0.081 |
GO T1 | 308,000 | 714,000 | −1103 | 0.270 |
GO T2 | 308,000 | 714,000 | −1103 | 0.270 |
GO T3 | 308,000 | 714,000 | −1103 | 0.270 |
PD T0 | 279,500 | 685,500 | −805 | 0.421 |
PD T1 | 278,500 | 684,500 | −824 | 0.410 |
PD T2 | 283,000 | 689,000 | −739 | 0.460 |
PD T3 | 299,500 | 705,500 | −428 | 0.669 |
CAL T0 | 278,500 | 684,500 | −824 | 0.410 |
CAL T1 | 272,000 | 678,000 | −947 | 0.343 |
CAL T2 | 253,000 | 659,000 | −1307 | 0.191 |
CAL T3 | 259,000 | 665,000 | −1194 | 0.232 |
Statistic Tests a,b | ||||
---|---|---|---|---|
Test | GO T0 | GO T1 | GO T2 | GO T3 |
H of Kruskal-Wallis | 6434 | 2923 | 2923 | 2923 |
gl | 5 | 5 | 5 | 5 |
Asymptotic sign. | 0.266 | 0.712 | 0.712 | 0.712 |
Statistics Tests a,b | |||
---|---|---|---|
Periodontal Indices | H of Kruskal-Wallis | Gl | Asymptotic Sign. |
PI T0 | 7880 | 5 | 0.163 |
PI T1 | 5710 | 5 | 0.335 |
PI T2 | 11,280 | 5 | 0.046 |
PI T3 | 6776 | 5 | 0.238 |
GI T0 | 7979 | 5 | 0.157 |
GI T1 | 6311 | 5 | 0.277 |
GI T2 | 9126 | 5 | 0.104 |
GI T3 | 13,809 | 5 | 0.017 |
PD T0 | 7601 | 5 | 0.180 |
PD T1 | 6852 | 5 | 0.232 |
PD T2 | 7661 | 5 | 0.176 |
PD T3 | 7136 | 5 | 0.211 |
CAL T0 | 6757 | 5 | 0.239 |
CAL T1 | 3897 | 5 | 0.564 |
CAL T2 | 5310 | 5 | 0.379 |
CAL T3 | 6844 | 5 | 0.232 |
Correlations | ||
---|---|---|
IG T0 | ||
GO T0 | Pearson’s correlation | 1 |
N | 51 | |
PI T0 | Pearson’s correlation | 0.512 |
Sign. (with two tails) | 0.000 | |
N | 51 | |
GI T0 | Pearson’s correlation | 0.621 |
Sign. (with two tails) | 0.000 | |
N | 51 | |
PD T0 | Pearson’s correlation | 0.351 |
Sign. (with two tails) | 0.012 | |
N | 51 | |
CAL T0 | Pearson’s correlation | 0.358 |
Sign. (with two tails) | 0.010 | |
N | 51 |
Correlations | ||
---|---|---|
IG T1 | ||
GO T1 | Pearson’s correlation | 1 |
N | 51 | |
PI T1 | Pearson’s correlation | 0.625 |
Sign. (with two tails) | 0.000 | |
N | 51 | |
GI T1 | Pearson’s correlation | 0.455 |
Sign. (with two tails) | 0.001 | |
N | 51 | |
PD T1 | Pearson’s correlation | 0.243 |
Sign. (with two tails) | 0.085 | |
N | 51 | |
CAL T1 | Pearson’s correlation | 0.333 |
Sign. (with two tails) | 0.017 | |
N | 51 |
Correlations | ||
---|---|---|
IG T2 | ||
GO T2 | Pearson’s correlation | 1 |
N | 51 | |
PI T2 | Pearson’s correlation | 0.183 |
Sign. (with two tails) | 0.200 | |
N | 51 | |
GI T2 | Pearson’s correlation | 0.163 |
Sign. (with two tails) | 0.253 | |
N | 51 | |
PD T2 | Pearson’s correlation | 0.303 |
Sign. (with two tails) | 0.031 | |
N | 51 | |
CAL T2 | Pearson’s correlation | 0.383 |
Sign. (with two tails) | 0.006 | |
N | 51 |
Correlations | ||
---|---|---|
IG T3 | ||
GO T3 | Pearson’s correlation | 1 |
N | 51 | |
PI T3 | Pearson’s correlation | 0.183 |
Sign. (with two tails) | 0.200 | |
N | 51 | |
GI T3 | Pearson’s correlation | 0.163 |
Sign. (with two tails) | 0.253 | |
N | 51 | |
PD T3 | Pearson’s correlation | 0.303 |
Sign. (with two tails) | 0.031 | |
N | 51 | |
CAL T3 | Pearson’s correlation | 0.383 |
Sign. (with two tails) | 0.006 | |
N | 51 |
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Rapone, B.; Ferrara, E.; Santacroce, L.; Cesarano, F.; Arazzi, M.; Di Liberato, L.; Scacco, S.; Grassi, R.; Grassi, F.R.; Gnoni, A.; et al. Periodontal Microbiological Status Influences the Occurrence of Cyclosporine-A and Tacrolimus-Induced Gingival Overgrowth. Antibiotics 2019, 8, 124. https://doi.org/10.3390/antibiotics8030124
Rapone B, Ferrara E, Santacroce L, Cesarano F, Arazzi M, Di Liberato L, Scacco S, Grassi R, Grassi FR, Gnoni A, et al. Periodontal Microbiological Status Influences the Occurrence of Cyclosporine-A and Tacrolimus-Induced Gingival Overgrowth. Antibiotics. 2019; 8(3):124. https://doi.org/10.3390/antibiotics8030124
Chicago/Turabian StyleRapone, Biagio, Elisabetta Ferrara, Luigi Santacroce, Francesca Cesarano, Marta Arazzi, Lorenzo Di Liberato, Salvatore Scacco, Roberta Grassi, Felice Roberto Grassi, Antonio Gnoni, and et al. 2019. "Periodontal Microbiological Status Influences the Occurrence of Cyclosporine-A and Tacrolimus-Induced Gingival Overgrowth" Antibiotics 8, no. 3: 124. https://doi.org/10.3390/antibiotics8030124