Perspective: Stabilizing the Microbiome Skin-Gut-Brain Axis with Natural Plant Botanical Ingredients in Cosmetics
Abstract
:1. Introduction
2. Microbiome–Host Interaction through Immune System
3. Elaborating the Skin-Gut-Brain Axis and Various Host Neuroendocrine Pathways
4. Plant Botanicals that Affect Gut and Skin
5. Conclusions: Future Considerations for Correlating Plant Botanicals to Surface Microbiome and Their Role in the Concept of “Vibrational Cosmetics” Innovation
Conflicts of Interest
References
- Beri, K. Skin microbiome and host immunity applications in regenerative cosmetics and transdermal drug delivery. Future Sci. OA 2018. [Google Scholar] [CrossRef]
- Belkaid, Y.; Tamoutounour, S. The influence of skin microorganisms on cutaneous immunity. Nat. Rev. Immunol. 2016, 16, 353–366. [Google Scholar] [CrossRef] [PubMed]
- Sender, R.; Fuchs, S.; Milo, R. Revised estimates for the number of human and bacteria cells in the body. PLoS Biol. 2016, 14, e1002533. [Google Scholar] [CrossRef] [PubMed]
- Belkaid, Y.; Segre, J.A. Dialogue between skin microbiota and immunity. Science 2014, 346, 954–959. [Google Scholar] [CrossRef] [PubMed]
- Zeeuwen, P.L.; Boekhorst, J.; Van den Bogaard, E.H.; de Koning, H.D.; van de Kerkhof, P.M.; Saulnier, D.M.; van Swam, I.I.; van Hijum, S.A.; Kleerebezem, M.; Schalkwijk, J.; et al. Microbiome dynamics of human epidermis following skin barrier disruption. Genome Biol. 2012, 13, R101. [Google Scholar] [CrossRef] [PubMed]
- Craig, J.M. Atopic dermatitis and the intestinal microbiota in humans and dogs. Vet. Med. Sci. 2016, 2, 95–105. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Gupta, M.A.; Jarosz, P.; Gupta, A.K. Posttraumatic stress disorder (PTSD) and the dermatology patient. Clin. Dermatol. 2017, 35, 260–266. [Google Scholar] [CrossRef] [PubMed]
- Codoñer, F.M.; Ramírez-Bosca, A.; Climent, E.; Carrión-Gutierrez, M.; Guerrero, M.; Pérez-Orquín, J.M.; Horga de la Parte, J.; Genovés, S.; Ramón, D.; Navarro-López, V.; et al. Gut microbial composition in patients with psoriasis. Sci. Rep. 2018, 8, 3812. [Google Scholar] [CrossRef] [PubMed]
- Clapp, M.; Aurora, N.; Herrera, L.; Bhatia, M.; Wilen, E.; Wakefield, S. Gut microbiota’s effect on mental health: The gut-brain axis. Clin. Pract. 2017, 7, 987. [Google Scholar] [CrossRef] [PubMed]
- Clark, A.K.; Haas, K.N.; Sivamani, R.K. Edible plants and their influence on the gut microbiome and acne. Int. J. Mol. Sci. 2017, 18, 1070. [Google Scholar] [CrossRef] [PubMed]
- Glick-Bauer, M.; Yeh, M.-C. The health advantage of a vegan diet: Exploring the gut microbiota connection. Nutrients 2014, 6, 4822–4838. [Google Scholar] [CrossRef] [PubMed]
- Singh, R.K.; Chang, H.-W.; Yan, D.; Lee, K.M.; Ucmak, D.; Wong, K.; Abrouk, M.; Farahnik, B.; Nakamura, M.; Zhu, T.H.; et al. Influence of diet on the gut microbiome and implications for human health. J. Transl. Med. 2017, 15, 73. [Google Scholar] [CrossRef] [PubMed]
- Kelly, J.R.; Minuto, C.; Cryan, J.F.; Clarke, G.; Dinan, T.G. Cross talk: The microbiota and neurodevelopmental disorders. Front. Neurosci. 2017, 11, 490. [Google Scholar] [CrossRef] [PubMed]
- Trehan, S.; Michniak-Kohn, B.; Beri, K. Plant stem cells in cosmetics: Current trends and future directions. Future Sci. OA 2017, 3, FSO226. [Google Scholar] [CrossRef] [PubMed]
- Morus, M.; Baran, M.; Rost-Roszkowska, M.; Skotnicka-Graca, U. Plant stem cells as innovation in cosmetics. Acta Pol. Pharm. 2014, 71, 701–707. [Google Scholar] [PubMed]
- Korkina, L.G.; Mayer, W.; de Luca, C. Meristem plant cells as a sustainable source of redox actives for skin rejuvenation. Biomolecules 2017, 7, 40. [Google Scholar] [CrossRef] [PubMed]
- Lin, T.K.; Zhong, L.; Santiago, J.L. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int. J. Mol. Sci. 2017, 19, 70. [Google Scholar] [CrossRef] [PubMed]
- Beri, K. A future perspective for regenerative medicine, understanding the concept of vibrational medicine. Future Sci. OA 2018, 4. [Google Scholar] [CrossRef] [PubMed]
- Gunasekara, T.; Radhika, N.; Ragunathan, K.K.; Gunathilaka, D.; Weerasekera, M.M.; Hewageegana, H.; Arawwawala, L.A.D.M.; Fernando, S. Determination of antimicrobial potential of five herbs used in Ayurveda Practices against Candida albicans, Candida parapsilosis and methicillin resistant Staphylococcus aureus. Anc. Sci. Life 2017, 36, 187–190. [Google Scholar] [CrossRef] [PubMed]
- Mukherjee, P.K.; Harwansh, R.K.; Bahadur, S.; Banerjee, S.; Kar, A.; Chanda, J.; Biswas, S.; Ahmmed, S.M.; Katiyar, C.K. Development of Ayurveda—Tradition to trend. J. Ethnopharmacol. 2017, 197, 10–24. [Google Scholar] [CrossRef] [PubMed]
- Sarkar, C.; Webster, C.; Gallacher, J. Residential greenness and prevalence of major depressive disorders: A cross-sectional, observational, associational study of 94 879 adult UK Biobank participants. Lancet Planet. Health 2018, 2, e162–e173. [Google Scholar] [CrossRef]
- PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Aromatherapy and Essential Oils (PDQ®): Health Professional Version. Available online: http://www.ncbi.nlm.nih.gov/books/NBK65874/ (accessed on 24 March 2018).
- Orchard, A.; van Vuuren, S.F.; Viljoen, A.; Kamatou, G. The in vitro antimicrobial evaluation of commercially essential oils and their combinations against acne. Int. J. Cosmet. Sci. 2018. [Google Scholar] [CrossRef] [PubMed]
- Han, X.; Beaumont, C.; Stevens, N. Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells. Biochem. Open 2017, 5, 1–7. [Google Scholar] [CrossRef] [PubMed]
- Concha, J.; Soto, C.; Chamy, R.; Zúñiga, M.E. Effect of rosehip extraction process on oil and defatted meal physicochemical properties. J. Am. Oil Chem. Soc. 2006, 83, 771–775. [Google Scholar] [CrossRef]
- Memariani, Z.; Moeini, R.; Hamedi, S.S.; Gorji, N.; Mozaffarpur, S.A. Medicinal plants with antithrombotic property in Persian medicine: A mechanistic review. J. Thromb. Thrombolysis 2018, 45, 158–179. [Google Scholar] [CrossRef] [PubMed]
- Reis, D.; Jones, T.T. Frankincense essential oil as a supportive therapy for cancer-related fatigue: A case study. Holist. Nurs. Pract. 2018, 32, 140–142. [Google Scholar] [CrossRef] [PubMed]
- Han, X.; Rodriguez, D.; Parker, T.L. Biological activities of frankincense essential oil in human dermal fibroblasts. Biochim. Open 2017, 4, 31–35. [Google Scholar] [CrossRef] [PubMed]
- Haroyan, A.; Mukuchyan, V.; Mkrtchyan, N.; Minasyan, N.; Gasparyan, S.; Sargsyan, A.; Narimanyan, M.; Hovhannisyan, A. Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: A comparative, randomized, double-blind, placebo-controlled study. BMC Complement. Altern. Med. 2018, 18, 7. [Google Scholar] [CrossRef] [PubMed]
- Burusapat, C.; Supawan, M.; Pruksapong, C.; Pitiseree, A.; Suwantemee, C. Topical aloe vera gel for accelerated wound healing of split-thickness skin graft donor sites: A double-blind, randomized, controlled trial and systematic review. Plast. Reconstr. Surg. 2018. [Google Scholar] [CrossRef] [PubMed]
- Arora, M.K.; Sarup, Y.; Tomar, R.; Singh, M.; Kumar, P. Amelioration of diabetes-induced diabetic nephropathy by aloe vera: Implication of oxidative stress and hyperlipidemia. J. Diet. Suppl. 2018, 1–18. [Google Scholar] [CrossRef] [PubMed]
- Sundaram, D.; Narayanan, R.K.; Vadakkepurayil, K. A comparative evaluation on antimicrobial effect of honey, neem leaf extract and sodium hypochlorite as intracanal irrigant: An ex-vivo study. J. Clin. Diagn. Res. 2016, 10, ZC88–ZC91. [Google Scholar] [CrossRef] [PubMed]
- Hao, F.; Kumar, S.; Yadav, N.; Chandra, D. Neem components as potential agents for cancer prevention and treatment. Biochim. Biophys. Acta 2014, 1846, 247–257. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- McCann, M.J.; Johnston, S.; Reilly, K.; Men, X.; Burgess, E.J.; Perry, N.B.; Roy, N.C. The effect of turmeric (Curcuma longa) extract on the functionality of the solute carrier protein 22 A4 (SLC22A4) and interleukin-10 (IL-10) variants associated with inflammatory bowel disease. Nutrients 2014, 6, 4178–4190. [Google Scholar] [CrossRef] [PubMed]
- Bagchi, D.; Swaroop, A.; Preuss, H.G.; Bagchi, M. Free radical scavenging, antioxidant and cancer chemoprevention by grape seed proanthocyanidin: An overview. Mutat. Res. 2014, 768, 69–73. [Google Scholar] [CrossRef] [PubMed]
- Moy, R.L.; Levenson, C. Sandalwood album oil as a botanical therapeutic in dermatology. J. Clin. Aesthet. Dermatol. 2017, 10, 34–39. [Google Scholar] [PubMed]
- Muthu, P.R.; Bobby, Z.; Sankar, P.; Vickneshwaran, V.; Jacob, S.E. Amla (Emblica officinalis) improves hepatic and renal oxidative stress and the inflammatory response in hypothyroid female wistar rats fed with a high-fat diet. J. Basic Clin. Physiol. Pharmacol. 2018, 29, 175–184. [Google Scholar] [CrossRef] [PubMed]
- Yadav, S.S.; Singh, M.K.; Singh, P.K.; Kumar, V. Traditional knowledge to clinical trials: A review on therapeutic actions of Emblica officinalis. Biomed. Pharmacother. 2017, 93, 1292–1302. [Google Scholar] [CrossRef] [PubMed]
- Beri, K. The impact of the “yogic lifestyle” on cancer prognosis and survival: Can we target cancer stem cells with yoga? Int. J. Yoga 2017, 10, 95–98. [Google Scholar] [CrossRef] [PubMed]
- Beri, K. Breathing to younger skin: “reversing the molecular mechanism of skin aging with yoga.”. Future Sci. OA 2016, 2, FSO122. [Google Scholar] [CrossRef] [PubMed]
- Cosmetics Industry—Statistics & Facts. Available online: https://www.statista.com/topics/3137/cosmetics-industry/ (accessed on 12 October 2017).
- Peterson, C.T.; Sharma, V.; Uchitel, S.; Denniston, K.; Chopra, D.; Mills, P.J.; Peterson, S.N. Prebiotic Potential of Herbal Medicines Used in Digestive Health and Disease. J. Altern. Complement. Med. 2018. [Google Scholar] [CrossRef] [PubMed]
- Peterson, C.T.; Denniston, K.; Chopra, D. Therapeutic uses of Triphala in Ayurvedic medicine. J. Altern. Complement. Med. 2017, 23, 607–614. [Google Scholar] [CrossRef] [PubMed]
- Varma, S.R.; Sivaprakasam, T.O.; Mishra, A.; Kumar, L.S.; Prakash, N.S.; Prabhu, S.; Ramakrishnan, S. Protective effects of Triphala on dermal fibroblasts and human keratinocytes. PLoS ONE 2016, 11, e0145921. [Google Scholar] [CrossRef] [PubMed]
- Vadde, R.; Radhakrishnan, S.; Reddivari, L.; Vanamala, J.K.P. Triphala Extract Suppresses Proliferation and Induces Apoptosis in Human Colon Cancer Stem Cells via Suppressing c-Myc/Cyclin D1 and Elevation of Bax/Bcl-2 Ratio. BioMed Res. Int. 2015, 2015, 649263. [Google Scholar] [CrossRef] [PubMed]
- Belapurkar, P.; Goyal, P.; Tiwari-Barua, P. Immunomodulatory Effects of Triphala and its Individual Constituents: A Review. Indian J. Pharm. Sci. 2014, 76, 467–475. [Google Scholar] [PubMed]
- O’Neill, C.A.; Monteleone, G.; McLaughlin, J.T.; Paus, R. The gut-skin axis in health and disease: A paradigm with therapeutic implications. BioEssays 2016, 38, 1167–1176. [Google Scholar] [CrossRef] [PubMed]
- Denda, M.; Tekai, K.; Denda, S. How does epidermal pathology interact with mental state? Med. Hypotheses 2013, 80, 194–196. [Google Scholar] [CrossRef] [PubMed]
- Prescott, S.L.; Larcombe, D.L.; Logan, A.C.; West, C.; Burks, W.; Caraballo, L.; Levin, M.; Van Etten, E.; Horwitz, P.; Kozyrskyj, A.; et al. The skin microbiome: Impact of modern environments on skin ecology, barrier integrity, and systemic immune programming. World Allergy Organ. J. 2017, 10, 29. [Google Scholar] [CrossRef] [PubMed]
- Beri, K.; Milgraum, S.S. Neocollagenesis in deep and superficial dermis by combining fractionated Q-switched ND: YAG 1064-nm with topical plant stem cell extract and N-acetyl glucosamine: Open case series. J. Drugs Dermatol. 2015, 14, 1342–1346. [Google Scholar] [PubMed]
- Denda, M. Epidermis as the third brain. Dermatol. Sin. 2015, 33, 70–73. [Google Scholar] [CrossRef]
Plant Herb/Extract | Skin Effect | Gut Effect/Systemic Effect. Mechanism of Action |
---|---|---|
Amla (Indian Goose Berry) Phyllanthus emblica All parts of the plant and fruit are used for various symptoms in Ayurvedic medicine | Cooling effect, antioxidant As has high concentrations of Ascorbic acid | Aids in digestion when ingested orally, often used as a post meal digestive drink in Ayurveda to balance the Dosha imbalance Maintenance of telomere length is facilitated by an increase in telomerase activity * |
Frankincense Often used as tincture or essential oil Genus Boswellia in the family Burseraceae | Stimulates dermal fibroblast Improving tone texture and clarity | Inflammation, immune response, and tissue remodeling. Aromatic effects. |
Rosehip seed Rosehip, also called rose haw and rose hep, is the accessory fruit of the rose plant. Used as oil/herbal Tea/tincture. | Antioxidant, carrier oil for other essential oils, stimulate collagen | Anti-inflammatory, high in vitamin A, oleic, linoleic essential amino acids. |
Aloe vera gel/juice Genus: Aloe. | Wound healing and regeneration | Reduces diabetic neuropathy * |
Rose, genus Rosa Rosewater/rose extract/rose essential oil/tincture | Aromatic, soothing and cooling effect | Immunomodulation, anti-inflammatory actions but needs more detailed testing to confirm. |
Neem Azadirachta indica Tree in the mahogany family Meliaceae. | Antibacterial, anti-inflammatory, antioxidant, anti-diabetic, antihelminthic | Anticancer. Anti-inflammatory |
Turmeric (Curcuma longa) | Anti-inflammatory, antimicrobial Wound healing | Inflammatory bowel disease Action via various pathways Anticancer? |
Grapeseed | Antioxidant, anti-pigment, anti-inflammatory | Ingested reduced blood pressure and cardiovascular risk Anticancer, anti-inflammatory effects on cells. |
Sandalwood genus Santalam Oil/powder | Anti-inflammatory, anti-pigment | Known to act through multiple immune pathways. |
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Beri, K. Perspective: Stabilizing the Microbiome Skin-Gut-Brain Axis with Natural Plant Botanical Ingredients in Cosmetics. Cosmetics 2018, 5, 37. https://doi.org/10.3390/cosmetics5020037
Beri K. Perspective: Stabilizing the Microbiome Skin-Gut-Brain Axis with Natural Plant Botanical Ingredients in Cosmetics. Cosmetics. 2018; 5(2):37. https://doi.org/10.3390/cosmetics5020037
Chicago/Turabian StyleBeri, Kavita. 2018. "Perspective: Stabilizing the Microbiome Skin-Gut-Brain Axis with Natural Plant Botanical Ingredients in Cosmetics" Cosmetics 5, no. 2: 37. https://doi.org/10.3390/cosmetics5020037