Epicardial Lineages
Abstract
:1. The Epicardium—A Cardiac Tissue of Extracardiac Origin
2. Proepicardial Lineage Tracing in Chick Development—Fibroblasts, Coronary Smooth Muscle Cells and Possibly Endothelial Cells
3. Epicardial Lineage Tracing in Mouse Development—An Epicardial Origin of Myocardial Cells?
4. Epicardial Fates in Zebrafish Development—Fibroblasts and Smooth Muscle Cells and Nothing Else
5. In Vitro Studies Reveal Proepicardial and Epicardial Potentials
Method | Reference | SE | cSMC | pCF | iCF | AVV | Endo | cEC | CM |
---|---|---|---|---|---|---|---|---|---|
Chick | |||||||||
Dye labeling | [17] | X | |||||||
[19] | X | X | |||||||
Retroviral labeling | [16] | X | X | X (PE) | |||||
[17] | X | X | X | X | X | ||||
[19] | X | X | |||||||
Quail-chick chimeras | [12] | - | |||||||
[15] | X | X | X | X | X | ||||
[18] | X | X | X | X | X | X | - | ||
[19] | X | X | X | X | X | X | |||
PE explant | [41] | X | |||||||
[19] | X | ||||||||
[40] | X | X | |||||||
[42] | X | ||||||||
[20] | X | ||||||||
Epicardial explant | [43] | X | |||||||
Mouse | |||||||||
Dye labeling | [26] | X | |||||||
[44] | X | X | |||||||
Lineage-tracing | |||||||||
MslnCln | [35] | X | X | - | - | ||||
Sema3dtm1.1(GFP/cre)Cjt | [37] | X | X | X | X | X | X | ||
Tbx18tm2(cre)Sev | [26] | X | X | - | X | ||||
Tbx18tm4(cre)Akis | [28] | - | |||||||
[29] | X | X | X | - | |||||
Tcf21MerCreMer | [34] | X | X | X | X | - | - | ||
Tg(Scx-GFP/cre)1Stzr | [36] | X | X | X | X | ||||
Wt1tm1(EGFP/cre)Wtp | [27] | X | X | X | |||||
[32] | X | ||||||||
Wt1tm2(cre/ERT2)Wtp | [26] | X | X | X | |||||
[30] | X | X* | - | ||||||
[31] | X* | ||||||||
PE explant | [45] | X | |||||||
[36] | X | ||||||||
[39] | X | X | X | X | X | ||||
Epicardial explant | [46] | X | |||||||
[47] | X | ||||||||
[39] | X | X | X | - | - | ||||
Zebrafish | |||||||||
Tg(tcf21:DsRed2)pd3 | [38] | X | X | X | - | - |
6. Mobilization and Differentiation of Epicardial Cells in The Injured Heart—Studies in Zebrafish and Mice
Injury | Method | iC | CF | pSC | CM | EC |
---|---|---|---|---|---|---|
Zebrafish | ||||||
Cryoinjury | Transplantation [51] | X | X | X | - | - |
(infarct model) | Lineage-tracing | X | X | X | - | - |
Ventricular resection | Lineage-tracing | X | - | - | ||
Mouse | ||||||
Myocardial infarction | Lineage-tracing | X | X | X | X | X /- |
Lineage-tracing | X | X | X | - | - | |
Lineage-tracing | X | X | - | |||
7. Summary and Perspectives
Acknowledgments
References and Notes
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Greulich, F.; Kispert, A. Epicardial Lineages. J. Dev. Biol. 2013, 1, 32-46. https://doi.org/10.3390/jdb1010032
Greulich F, Kispert A. Epicardial Lineages. Journal of Developmental Biology. 2013; 1(1):32-46. https://doi.org/10.3390/jdb1010032
Chicago/Turabian StyleGreulich, Franziska, and Andreas Kispert. 2013. "Epicardial Lineages" Journal of Developmental Biology 1, no. 1: 32-46. https://doi.org/10.3390/jdb1010032