Stem Bark-Mediated Green Synthesis of Silver Nanoparticles from Pyrus pashia: Characterization, Antioxidant, and Antibacterial Properties
, Debendra Acharya 4, Ek Raj Baral 5, Kisan Chhetri 4,* and Surya Kant Kalauni 2,*
Shyh-Jiun Liu
Round 1
Reviewer 1 Report
1. The main question addressed by the research is demonstration of the possibility and probably further practical use of
stem-bark-mediated green synthesis of silver nanoparticles (SNP) from Pyrus
pashia: characterization (size, form, shape), antioxidant (scavenging of DPPH radical), and antibacterial properties of obtained SNP .
2. I consider that the topic is original and/or relevant in the field. It does
address a specific gap in the field.
3. Regarding the subject area compared with other published material it is in consensus with other data using different species of oriental vegetables for preparation of silver nanoparticles.
4. The methodology is appropriate and could be used without further controls.
5. The conclusions are consistent with the evidence and arguments presented
and they address to the main question posed.
6. The references are appropriate. Ref.54 should be verified and improved.
7. Aricle MS could be published. Reference no.54 should be precised.
Author Response
The response to the reviewer's comments is attached in a Word file.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Title: Stem Bark-Mediated Green Synthesis of Silver Nanoparticles from Pyrus pashia: Characterization, Antioxidant, and Antibacterial Properties
Article Type: full article
Manuscript Number: inorganics-2430761-v1
In this article, the AgNPs are synthesized from the stem barks of the Pyrus pashia medicinal plant using a biosynthetic strategy. The synthesized AgNPs demonstrated enhanced DPPH free radical scavenging capacity compared to the aqueous extract, with IC50 values of 10.67 ± 0.05 μg/mL and 13.66 ± 0.35 μg/mL respectively.
My recommendation is that the authors carefully consider the below points, revise appropriately.
1. The authors may consider some representative word in the keywords. Some less prominent key words could be replaced by significant word.
2. My suggestion is that the authors may emphasize the contribution of this method which superiority than the others that has published before.
3. The authors should carefully check not only the name but also symbol and font style in full article as well as carefully check the English sentence and symbol in full article. Ex. Page 8 line284~285Table 3; The distance of the table needs to be adjusted moderately so that the data is on the same line as well as the “PC”.
4. My suggestion is that the authors may consider showing the applications for each case that were published in previous literature to enhance the cognition for reader.
Please check the rhetoric and some word spellings throughout the article.
Author Response
The response to the reviewer's comments is attached in a Word file.
Author Response File: Author Response.pdf
Reviewer 3 Report
In this article, authors demonstrated their results on synthesis of At nanoparticles using stem barks of the Pyrus pashia. Particle size, phase, morphology and distribution are properly characterized by various methods, and antibacterial properties are confirmed.
I do have a question for the authors: for bio synthesis of Ag nanoparticles, there has been plenty of reports on different biomass, like geranium leaf, citrus sinensis peel etc. Will you be able to compare the choice current plant with any existing bio/chemical/commercial source and comment on the anti-bacterial property?
Good
Author Response
The response to the reviewer's comments is attached in a Word file.
Author Response File: Author Response.pdf
