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Bioengineering, Volume 10, Issue 9

2023 September - 117 articles

Cover Story: Muscle tissue engineering aims to repair or regenerate defective muscle tissue lost by trauma or disease. Despite its great potential, the number of clinical trials in this field is very limited. In this context, several parameters need to be addressed towards the development of advanced regenerative therapies employing myogenic cells. Bioprocess considerations covering the cell isolation step starting from different tissue sources (i.e., stem/progenitor cells vs. more committed precursors), as well as the need for robust and cost-effective protocols featuring easy scalability envisioning clinical applications, which are approached herein. Overall, the ultimate goal would be to obtain clinically relevant cell numbers, while maintaining cell/tissue identity and functionality. View this paper
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Articles (117)

  • Article
  • Open Access
2 Citations
4,296 Views
18 Pages

Joint Image Reconstruction and Super-Resolution for Accelerated Magnetic Resonance Imaging

  • Wei Xu,
  • Sen Jia,
  • Zhuo-Xu Cui,
  • Qingyong Zhu,
  • Xin Liu,
  • Dong Liang and
  • Jing Cheng

Magnetic resonance (MR) image reconstruction and super-resolution are two prominent techniques to restore high-quality images from undersampled or low-resolution k-space data to accelerate MR imaging. Combining undersampled and low-resolution acquisi...

(This article belongs to the Special Issue Novel MRI Techniques and Biomedical Image Processing)
  • Article
  • Open Access
5 Citations
4,749 Views
11 Pages

(1) Background: The physical fitness (PF) of hearing-impaired students has always been an international research hotspot since hearing-impaired students have difficulty in social interactions such as exercise or fitness programs. Sports interventions...

(This article belongs to the Special Issue Biomechanics, Health, Disease and Rehabilitation)
  • Article
  • Open Access
3 Citations
2,727 Views
17 Pages

Directly applying brain signals to operate a mobile manned platform, such as a vehicle, may help people with neuromuscular disorders regain their driving ability. In this paper, we developed a novel electroencephalogram (EEG) signal-based driver&ndas...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
7 Citations
3,654 Views
17 Pages

Low-Data Drug Design with Few-Shot Generative Domain Adaptation

  • Ke Liu,
  • Yuqiang Han,
  • Zhichen Gong and
  • Hongxia Xu

Developing new drugs for emerging diseases, such as COVID-19, is crucial for promoting public health. In recent years, the application of artificial intelligence (AI) has significantly advanced drug discovery pipelines. Generative models, such as gen...

(This article belongs to the Special Issue Artificial Intelligence (AI) in Biomedicine)
  • Article
  • Open Access
26 Citations
3,684 Views
17 Pages

sEMG Spectral Analysis and Machine Learning Algorithms Are Able to Discriminate Biomechanical Risk Classes Associated with Manual Material Liftings

  • Leandro Donisi,
  • Deborah Jacob,
  • Lorena Guerrini,
  • Giuseppe Prisco,
  • Fabrizio Esposito,
  • Mario Cesarelli,
  • Francesco Amato and
  • Paolo Gargiulo

Manual material handling and load lifting are activities that can cause work-related musculoskeletal disorders. For this reason, the National Institute for Occupational Safety and Health proposed an equation depending on the following parameters: int...

(This article belongs to the Special Issue Machine Learning for Biomedical Applications, Volume II)
  • Article
  • Open Access
6 Citations
3,753 Views
13 Pages

Zirconia Dental Implants: A Closer Look at Surface Condition and Intrinsic Composition by SEM-EDX

  • Alex Tchinda,
  • Augustin Lerebours,
  • Richard Kouitat-Njiwa and
  • Pierre Bravetti

Modern dental implantology is based on a set of more or less related first-order parameters, such as the implant surface and the intrinsic composition of the material. For decades, implant manufacturers have focused on the research and development of...

(This article belongs to the Special Issue Materials in Dental and Maxillofacial Surgery and Regenerative Medicine)
  • Article
  • Open Access
8 Citations
3,028 Views
14 Pages

Improved Network and Training Scheme for Cross-Trial Surface Electromyography (sEMG)-Based Gesture Recognition

  • Qingfeng Dai,
  • Yongkang Wong,
  • Mohan Kankanhali,
  • Xiangdong Li and
  • Weidong Geng

To enhance the performance of surface electromyography (sEMG)-based gesture recognition, we propose a novel network-agnostic two-stage training scheme, called sEMGPoseMIM, that produces trial-invariant representations to be aligned with corresponding...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Article
  • Open Access
6 Citations
2,619 Views
12 Pages

Accurate identification of lesions and their use across different medical institutions are the foundation and key to the clinical application of automatic diabetic retinopathy (DR) detection. Existing detection or segmentation methods can achieve acc...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Review
  • Open Access
4 Citations
3,553 Views
15 Pages

Bacterial Membrane Vesicles for In Vitro Catalysis

  • Meghna Thakur,
  • Scott N. Dean,
  • Julie C. Caruana,
  • Scott A. Walper and
  • Gregory A. Ellis

The use of biological systems in manufacturing and medical applications has seen a dramatic rise in recent years as scientists and engineers have gained a greater understanding of both the strengths and limitations of biological systems. Biomanufactu...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
7 Citations
3,905 Views
38 Pages

A New Generative Model for Textual Descriptions of Medical Images Using Transformers Enhanced with Convolutional Neural Networks

  • Artur Gomes Barreto,
  • Juliana Martins de Oliveira,
  • Francisco Nauber Bernardo Gois,
  • Paulo Cesar Cortez and
  • Victor Hugo Costa de Albuquerque

The automatic generation of descriptions for medical images has sparked increasing interest in the healthcare field due to its potential to assist professionals in the interpretation and analysis of clinical exams. This study explores the development...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
6 Citations
3,172 Views
13 Pages

Elderly people usually have poorer surgical tolerance and a higher incidence of complications when undergoing revision surgery after posterior instrumented lumbar fusion (PILF). Full-endoscopic transforaminal surgery is a safe and effective option, b...

(This article belongs to the Section Regenerative Engineering)
  • Review
  • Open Access
25 Citations
11,155 Views
27 Pages

Recent Advancements in Glaucoma Surgery—A Review

  • Bryan Chin Hou Ang,
  • Sheng Yang Lim,
  • Bjorn Kaijun Betzler,
  • Hon Jen Wong,
  • Michael W. Stewart and
  • Syril Dorairaj

Surgery has long been an important treatment for limiting optic nerve damage and minimising visual loss in patients with glaucoma. Numerous improvements, modifications, and innovations in glaucoma surgery over recent decades have improved surgical sa...

(This article belongs to the Special Issue Meeting Challenges in the Diagnosis and Treatment of Glaucoma)
  • Article
  • Open Access
1 Citations
2,635 Views
13 Pages

Acetabular Revision with McMinn Cup: Development and Application of a Patient-Specific Targeting Device

  • Zoltán Csernátony,
  • Sándor Manó,
  • Dániel Szabó,
  • Hajnalka Soósné Horváth,
  • Ágnes Éva Kovács and
  • Loránd Csámer

Background: Surgeries of severe periacetabular bone defects (Paprosky ≥ 2B) are a major challenge in current practice. Although solutions are available for this serious clinical problem, they all have their disadvantages as well as their advantage...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
17 Citations
4,903 Views
11 Pages

Augmented Reality Surgical Navigation in Minimally Invasive Spine Surgery: A Preclinical Study

  • Xin Huang,
  • Xiaoguang Liu,
  • Bin Zhu,
  • Xiangyu Hou,
  • Bao Hai,
  • Dongfang Yu,
  • Wenhao Zheng,
  • Ranyang Li,
  • Junjun Pan and
  • Haijun Zeng
  • + 2 authors

Background: In minimally invasive spine surgery (MISS), where the surgeon cannot directly see the patient’s internal anatomical structure, the implementation of augmented reality (AR) technology may solve this problem. Methods: We combined AR,...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
19 Citations
5,470 Views
21 Pages

Deep Learning of Speech Data for Early Detection of Alzheimer’s Disease in the Elderly

  • Kichan Ahn,
  • Minwoo Cho,
  • Suk Wha Kim,
  • Kyu Eun Lee,
  • Yoojin Song,
  • Seok Yoo,
  • So Yeon Jeon,
  • Jeong Lan Kim,
  • Dae Hyun Yoon and
  • Hyoun-Joong Kong

Background: Alzheimer’s disease (AD) is the most common form of dementia, which makes the lives of patients and their families difficult for various reasons. Therefore, early detection of AD is crucial to alleviating the symptoms through medica...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Article
  • Open Access
5 Citations
2,277 Views
13 Pages

This study focuses on developing and characterizing a novel 3-dimensional cell-laden micro-patterned porous structure from a mechanical engineering perspective. Tissue engineering holds great promise for repairing damaged organs but faces challenges...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
14 Citations
3,529 Views
15 Pages

Deep learning technology has achieved breakthrough research results in the fields of medical computer vision and image processing. Generative adversarial networks (GANs) have demonstrated a capacity for image generation and expression ability. This p...

(This article belongs to the Special Issue Artificial Intelligence in Biomedical Imaging)
  • Article
  • Open Access
13 Citations
4,227 Views
19 Pages

Enterobacter hormaechei is part of the Enterobacter cloacae complex (ECC), which is widespread in nature. It is a facultative Gram-negative bacterium of medical and industrial importance. We assessed the metabolic and genetic repertoires of a new Ent...

(This article belongs to the Special Issue Biological Production of Value-Added Products)
  • Article
  • Open Access
13 Citations
4,003 Views
21 Pages

Self-FI: Self-Supervised Learning for Disease Diagnosis in Fundus Images

  • Toan Duc Nguyen,
  • Duc-Tai Le,
  • Junghyun Bum,
  • Seongho Kim,
  • Su Jeong Song and
  • Hyunseung Choo

Self-supervised learning has been successful in computer vision, and its application to medical imaging has shown great promise. This study proposes a novel self-supervised learning method for medical image classification, specifically targeting ultr...

(This article belongs to the Special Issue Biomedical Imaging and Analysis of the Eye)
  • Article
  • Open Access
17 Citations
4,860 Views
16 Pages

Guar-Based Injectable Hydrogel for Drug Delivery and In Vitro Bone Cell Growth

  • Humendra Poudel,
  • Ambar B. RanguMagar,
  • Pooja Singh,
  • Adeolu Oluremi,
  • Nawab Ali,
  • Fumiya Watanabe,
  • Joseph Batta-Mpouma,
  • Jin Woo Kim,
  • Ahona Ghosh and
  • Anindya Ghosh

Injectable hydrogels offer numerous advantages in various areas, which include tissue engineering and drug delivery because of their unique properties such as tunability, excellent carrier properties, and biocompatibility. These hydrogels can be admi...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
3 Citations
2,150 Views
10 Pages

Efficacy of Fractional Laser on Steroid Receptors in GSM Patients

  • Stella Catunda Pinho,
  • Thais Heinke,
  • Paula Fernanda Santos Pallone Dutra,
  • Andreia Carmo,
  • Camilla Salmeron,
  • Luciana Karoleski,
  • Gustavo Focchi,
  • Neila Maria Góis Speck,
  • Beatrice Marina Pennati and
  • Ivaldo Silva

Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy. Methods: Twenty-five menop...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
4 Citations
7,613 Views
13 Pages

Influence of Lateral Sitting Wedges on the Rasterstereographically Measured Scoliosis Angle in Patients Aged 10–18 Years with Adolescent Idiopathic Scoliosis

  • Andreas Feustel,
  • Jürgen Konradi,
  • Claudia Wolf,
  • Janine Huthwelker,
  • Ruben Westphal,
  • Daniel Chow,
  • Christian Hülstrunk,
  • Philipp Drees and
  • Ulrich Betz

Adolescent idiopathic scoliosis (AIS) is a three-dimensional axial deviation of the spine diagnosed in adolescence. Despite a long daily sitting duration, there are no studies on whether scoliosis can be positively influenced by sitting on a seat wed...

(This article belongs to the Special Issue Recent Advances of Spine Biomechanics)
  • Review
  • Open Access
36 Citations
12,841 Views
20 Pages

Resistance training is an exercise modality that involves using weights or resistance to strengthen and tone muscles. It has become popular in recent years, with numerous people including it in their fitness routines to ameliorate their strength, mus...

(This article belongs to the Section Biosignal Processing)
  • Review
  • Open Access
31 Citations
6,522 Views
21 Pages

The increasing global population and urbanization have led to a pressing need for effective solutions to manage the organic fraction of municipal solid waste (OFMSW). High-solids anaerobic digestion (HS-AD) has garnered attention as a sustainable tec...

(This article belongs to the Special Issue From Residues to Bio-Based Products through Bioprocess Engineering)
  • Review
  • Open Access
22 Citations
4,689 Views
19 Pages

Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation (HD-ACI)

  • Pedro Guillén-García,
  • Isabel Guillén-Vicente,
  • Elena Rodríguez-Iñigo,
  • Marta Guillén-Vicente,
  • Tomás Fernando Fernández-Jaén,
  • Ramón Navarro,
  • Lucía Aboli,
  • Raúl Torres,
  • Steve Abelow and
  • Juan Manuel López-Alcorocho

Hyaline cartilage’s inability to self-repair can lead to osteoarthritis and joint replacement. Various treatments, including cell therapy, have been developed for cartilage damage. Autologous chondrocyte implantation (ACI) is considered the bes...

(This article belongs to the Special Issue Biomaterials for Cartilage and Bone Tissue Engineering)
  • Article
  • Open Access
9 Citations
3,109 Views
25 Pages

This study introduces a novel convolutional neural network (CNN) architecture, encompassing both single and multi-head designs, developed to identify a user’s locomotion activity while using a wearable lower limb robot. Our research involved 50...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Article
  • Open Access
11 Citations
4,365 Views
13 Pages

Super-resolution structured illumination microscopy (SR-SIM) is an optical fluorescence microscopy method which is suitable for imaging a wide variety of cells and tissues in biological and biomedical research. Typically, SIM methods use high spatial...

(This article belongs to the Special Issue Recent Advances in Biomedical Imaging)
  • Article
  • Open Access
6 Citations
3,984 Views
15 Pages

The blood-brain barrier (BBB) is a dynamic interface that regulates the molecular exchanges between the brain and peripheral blood. The permeability of the BBB is primarily regulated by the junction proteins on the brain endothelial cells. In vitro B...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
5 Citations
3,593 Views
15 Pages

Multi-Parameter Auto-Tuning Algorithm for Mass Spectrometer Based on Improved Particle Swarm Optimization

  • Mingzheng Jia,
  • Liang Li,
  • Baolin Xiong,
  • Le Feng,
  • Wenbo Cheng and
  • Wen-Fei Dong

Quadrupole mass spectrometers (QMS) are widely used for clinical diagnosis and chemical analysis. To obtain the best experimental results, mass spectrometers must be calibrated to an ideal setting before use. However, tuning the current QMS is challe...

(This article belongs to the Special Issue New Sight of Intelligent Algorithm Model and Medical Device in Bioengineering: Updates and Direction)
  • Systematic Review
  • Open Access
25 Citations
8,781 Views
19 Pages

Machine Learning for Medical Image Translation: A Systematic Review

  • Jake McNaughton,
  • Justin Fernandez,
  • Samantha Holdsworth,
  • Benjamin Chong,
  • Vickie Shim and
  • Alan Wang

Background: CT scans are often the first and only form of brain imaging that is performed to inform treatment plans for neurological patients due to its time- and cost-effective nature. However, MR images give a more detailed picture of tissue struct...

(This article belongs to the Special Issue Machine-Learning-Driven Medical Image Analysis)
  • Article
  • Open Access
5 Citations
3,010 Views
13 Pages

The Performance of a Deep Learning-Based Automatic Measurement Model for Measuring the Cardiothoracic Ratio on Chest Radiographs

  • Donguk Kim,
  • Jong Hyuk Lee,
  • Myoung-jin Jang,
  • Jongsoo Park,
  • Wonju Hong,
  • Chan Su Lee,
  • Si Yeong Yang and
  • Chang Min Park

Objective: Prior studies on models based on deep learning (DL) and measuring the cardiothoracic ratio (CTR) on chest radiographs have lacked rigorous agreement analyses with radiologists or reader tests. We validated the performance of a commercially...

(This article belongs to the Section Biosignal Processing)
  • Review
  • Open Access
6 Citations
8,432 Views
18 Pages

The inferior vena cava (IVC) is the largest vein in the body. It returns deoxygenated blood to the heart from the tissues placed under the diaphragm. The size and dynamics of the IVC depend on the blood volume and right atrial pressure, which are imp...

  • Article
  • Open Access
5 Citations
3,129 Views
12 Pages

Isolation and Biological Evaluation of Alfa-Mangostin as Potential Therapeutic Agents against Liver Fibrosis

  • Yi-Jen Liao,
  • Chun-Ya Lee,
  • Yuh-Ching Twu,
  • Fat-Moon Suk,
  • Tzu-Chieh Lai,
  • Ya-Ching Chang,
  • Yi-Cheng Lai,
  • Jing-Wei Yuan,
  • Hong-Ming Jhuang and
  • Ming-Hua Hsu
  • + 3 authors

The increased proliferation and activation of hepatic stellate cells (HSCs) are associated with liver fibrosis development. To date, there are no FDA-approved drugs for the treatment of liver cirrhosis. Augmentation of HSCs apoptosis is one of the re...

(This article belongs to the Section Biochemical Engineering)
  • Article
  • Open Access
3 Citations
3,046 Views
20 Pages

REM Sleep Stage Identification with Raw Single-Channel EEG

  • Gabriel Toban,
  • Khem Poudel and
  • Don Hong

This paper focused on creating an interpretable model for automatic rapid eye movement (REM) and non-REM sleep stage scoring for a single-channel electroencephalogram (EEG). Many methods attempt to extract meaningful information to provide to a learn...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
4 Citations
4,507 Views
18 Pages

Production of Astaxanthin by Animal Cells via Introduction of an Entire Astaxanthin Biosynthetic Pathway

  • Yousef Mohammed,
  • Ding Ye,
  • Mudan He,
  • Houpeng Wang,
  • Zuoyan Zhu and
  • Yonghua Sun

Astaxanthin is a fascinating molecule with powerful antioxidant activity, synthesized exclusively by specific microorganisms and higher plants. To expand astaxanthin production, numerous studies have employed metabolic engineering to introduce and op...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
12 Citations
2,988 Views
11 Pages

Automated Detection and Measurement of Dural Sack Cross-Sectional Area in Lumbar Spine MRI Using Deep Learning

  • Babak Saravi,
  • Alisia Zink,
  • Sara Ülkümen,
  • Sebastien Couillard-Despres,
  • Jakob Wollborn,
  • Gernot Lang and
  • Frank Hassel

Lumbar spine magnetic resonance imaging (MRI) is a critical diagnostic tool for the assessment of various spinal pathologies, including degenerative disc disease, spinal stenosis, and spondylolisthesis. The accurate identification and quantification...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
120 Citations
11,671 Views
10 Pages

The opacity of deep learning makes its application challenging in the medical field. Therefore, there is a need to enable explainable artificial intelligence (XAI) in the medical field to ensure that models and their results can be explained in a man...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Systematic Review
  • Open Access
32 Citations
11,643 Views
13 Pages

Orthognathic Surgery and Relapse: A Systematic Review

  • Angelo Michele Inchingolo,
  • Assunta Patano,
  • Fabio Piras,
  • Elisabetta de Ruvo,
  • Laura Ferrante,
  • Angela Di Noia,
  • Leonardo Dongiovanni,
  • Andrea Palermo,
  • Francesco Inchingolo and
  • Gianna Dipalma
  • + 1 author

Background: This review aimed to analyze the relapse in orthognathic surgery. Methods: PubMed, Scopus, and Web of Science databases were used to find papers that matched our topic dating from 1 January 2012 up to November 2022. Inclusion criteria wer...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
10 Citations
3,662 Views
18 Pages

Ultra-Low Intensity Post-Pulse Affects Cellular Responses Caused by Nanosecond Pulsed Electric Fields

  • Kamal Asadipour,
  • Carol Zhou,
  • Vincent Yi,
  • Stephen J. Beebe and
  • Shu Xiao

High-intensity nanosecond pulse electric fields (nsPEF) can preferentially induce various effects, most notably regulated cell death and tumor elimination. These effects have almost exclusively been shown to be associated with nsPEF waveforms defined...

(This article belongs to the Special Issue Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 2nd Edition)
  • Review
  • Open Access
1 Citations
3,966 Views
23 Pages

Bioprocessing Considerations towards the Manufacturing of Therapeutic Skeletal and Smooth Muscle Cells

  • Teresa Franchi-Mendes,
  • Marília Silva,
  • Ana Luísa Cartaxo,
  • Ana Fernandes-Platzgummer,
  • Joaquim M. S. Cabral and
  • Cláudia L. da Silva

Tissue engineering approaches within the muscle context represent a promising emerging field to address the current therapeutic challenges related with multiple pathological conditions affecting the muscle compartments, either skeletal muscle or smoo...

(This article belongs to the Special Issue Design, Optimization and Scale-Up of Industrial Bioprocess)
  • Brief Report
  • Open Access
5 Citations
4,576 Views
9 Pages

Milk Casein Inhibits Effect of Black Tea Galloylated Theaflavins to Inactivate SARS-CoV-2 In Vitro

  • Maiko Nakashio,
  • Eriko Ohgitani,
  • Masaharu Shin-Ya,
  • Masaya Kawamoto,
  • Masaki Ichitani,
  • Makoto Kobayashi,
  • Takanobu Takihara,
  • Hitoshi Kinugasa,
  • Hiroyasu Ishikura and
  • Osam Mazda

Continuing caution is required against the potential emergence of SARS-CoV-2 novel mutants that could pose the next global health and socioeconomical threats. If virus in saliva can be inactivated by a beverage, such a beverage may be useful because...

(This article belongs to the Special Issue Bioactive Formulations in Agri-Food-Pharma: Source and Applications, Volume III)
  • Article
  • Open Access
8 Citations
3,260 Views
17 Pages

Spinal Cord Epidural Stimulation Improves Lower Spine Sitting Posture Following Severe Cervical Spinal Cord Injury

  • Kundan Joshi,
  • Enrico Rejc,
  • Beatrice Ugiliweneza,
  • Susan J. Harkema and
  • Claudia A. Angeli

Cervical spinal cord injury (SCI) leads to impaired trunk motor control, negatively impacting the performance of activities of daily living in the affected individuals. Improved trunk control with better sitting posture has been previously observed d...

(This article belongs to the Special Issue Biomechanics-Based Motion Analysis, Volume II)
  • Review
  • Open Access
11 Citations
3,736 Views
15 Pages

When combined with patient information provided by advanced imaging techniques, computational biomechanics can provide detailed patient-specific information about stresses and strains acting on tissues that can be useful in diagnosing and assessing t...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Article
  • Open Access
12 Citations
3,119 Views
13 Pages

Bio-Inspired Fiber Reinforcement for Aortic Valves: Scaffold Production Process and Characterization

  • Christian A. Boehm,
  • Christine Donay,
  • Andreas Lubig,
  • Stephan Ruetten,
  • Mahmoud Sesa,
  • Alicia Fernández-Colino,
  • Stefanie Reese and
  • Stefan Jockenhoevel

The application of tissue-engineered heart valves in the high-pressure circulatory system is still challenging. One possible solution is the development of biohybrid scaffolds with textile reinforcement to achieve improved mechanical properties. In t...

(This article belongs to the Special Issue Feature Papers in Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
1 Citations
2,108 Views
20 Pages

Direct Estimation of Equivalent Bioelectric Sources Based on Huygens’ Principle

  • Georgia Theodosiadou,
  • Dimitrios G. Arnaoutoglou,
  • Ioannis Nannis,
  • Sotirios Katsimentes,
  • Georgios Ch. Sirakoulis and
  • George A. Kyriacou

An estimation of the electric sources in the heart was conducted using a novel method, based on Huygens’ Principle, aiming at a direct estimation of equivalent bioelectric sources over the heart’s surface in real time. The main scope of this work was...

(This article belongs to the Special Issue Applications of Computational Modeling in Biomedical Image and Signal Processing)
  • Article
  • Open Access
6 Citations
3,661 Views
20 Pages

Photoacoustic (PA) imaging can be used to monitor high-intensity focused ultrasound (HIFU) therapies because ablation changes the optical absorption spectrum of the tissue, and this change can be detected with PA imaging. Multi-wavelength photoacoust...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
11 Citations
2,937 Views
15 Pages

Finite Element Evaluation of the Electric Field Distribution in a Non-Homogeneous Environment

  • Elisabetta Sieni,
  • Monica Dettin,
  • Annj Zamuner,
  • Maria Teresa Conconi,
  • Bianca Bazzolo,
  • Cristian Balducci,
  • Paolo Di Barba,
  • Michele Forzan,
  • Patrizia Lamberti and
  • Maria Evelina Mognaschi

Finite element analysis is used in this study to investigate the effect of media inhomogeneity on the electric field distribution in a sample composed of cells and their extracellular matrix. The sample is supposed to be subjected to very high pulsed...

(This article belongs to the Special Issue Advanced 3D Cell Culture Technologies and Formats)
  • Article
  • Open Access
9 Citations
7,802 Views
11 Pages

Efficient Removal of Dental Plaque Biofilm from Training Typodont Teeth via Water Flosser

  • Yue Wang,
  • Hongyu Gao,
  • Lili Chang,
  • Jingchen Xu,
  • Xueer Zhou,
  • Chaoliang Zhang and
  • Qiang Peng

Plaque biofilms play critical roles in the development of dental caries. Mechanical plaque control methods are considered to be most effective for plaque removal, such as brushing teeth or using flosser. Recently, water flosser has been paid much att...

(This article belongs to the Section Biochemical Engineering)
  • Article
  • Open Access
13 Citations
3,256 Views
11 Pages

A detailed three-dimensional (3D) head–neck (C0–C7) finite element (FE) model was developed and used to dictate the motions of each cervical spinal segment under static physiological loadings of flexion and extension with a magnitude of 1...

(This article belongs to the Special Issue Biomedical and Bioengineering Technology: Current Applications in Sports Monitoring and Health Care)
  • Article
  • Open Access
10 Citations
3,817 Views
11 Pages

Dental Auto Transplantation Success Rate Increases by Utilizing 3D Replicas

  • Peter Kizek,
  • Marcel Riznic,
  • Branislav Borza,
  • Lubos Chromy,
  • Karolina Kamila Glinska,
  • Zuzana Kotulicova,
  • Jozef Jendruch,
  • Radovan Hudak and
  • Marek Schnitzer

Dental autotransplantation is an effective alternative to conventional dental treatment, and it involves removing a tooth and repositioning it in a new position within the same patient. Although this procedure might pose more intraoperative challenge...

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Bioengineering - ISSN 2306-5354