Cyclic Voltammetric Behaviour and High-Performance Liquid Chromatography Amperometric Determination of Levamisole
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Reagents
2.2. Artificial Urine
2.3. Cyclic Voltammetry
2.4. High-Performance Liquid Chromatography
2.5. Electrochemical Detection
2.6. Hydrodynamic Voltammetry
2.7. Analytical Application
2.8. Limit of Detection and Limit of Quantification
3. Results
3.1. Cyclic Voltammetric Behaviour of Levamisole
3.2. Effect of pH on the Liquid Chromatographic Separation of Levamisole
3.3. Hydrodynamic Voltammetry
3.4. Calibration Plot, Limit of Detection, and Precision
3.5. Studies of Possible Interferences
4. Analytical Application
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Sample | Native, mg/L | Added mg/L | %Rec |
---|---|---|---|
1 | ND | 1.25 | 100.3 |
2 | ND | 1.25 | 100.3 |
3 | ND | 1.25 | 87.5 |
4 | ND | 1.25 | 97.1 |
5 | ND | 1.25 | 113 |
Mean | 99.6 | ||
SD | 8.14 | ||
%CV | 8.2 | ||
HorRat | 0.53 | ||
6 | ND | 2.33 | 93.0 |
7 | ND | 2.13 | 85.1 |
8 | ND | 2.17 | 86.7 |
9 | ND | 2.84 | 113.7 |
10 | ND | 2.37 | 94.6 |
Mean | 94.6 | ||
SD | 10.2 | ||
%CV | 10.8 | ||
HorRat | 0.78 |
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Chan, T.Y.J.; Honeychurch, K.C. Cyclic Voltammetric Behaviour and High-Performance Liquid Chromatography Amperometric Determination of Levamisole. Sci 2024, 6, 15. https://doi.org/10.3390/sci6010015
Chan TYJ, Honeychurch KC. Cyclic Voltammetric Behaviour and High-Performance Liquid Chromatography Amperometric Determination of Levamisole. Sci. 2024; 6(1):15. https://doi.org/10.3390/sci6010015
Chicago/Turabian StyleChan, Tsz Yan Joyce, and Kevin C. Honeychurch. 2024. "Cyclic Voltammetric Behaviour and High-Performance Liquid Chromatography Amperometric Determination of Levamisole" Sci 6, no. 1: 15. https://doi.org/10.3390/sci6010015