Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line †
1
Department of Pharmacognosy, Faculty of Pharmacy, Erciyes University, Melikgazi 38030, Turkey
2
Department of Biology Program of Botany, Faculty of Sciences, Selcuk University, Selçuklu 42250, Turkey
*
Author to whom correspondence should be addressed.
†
Presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8–11 November 2017.
Proceedings 2017, 1(10), 1055; https://doi.org/10.3390/proceedings1101055
Published: 14 November 2017
(This article belongs to the Proceedings of Proceedings of the 2nd International Conference on Natural Products for Cancer Prevention and Therapy)
Abstract
:The Apiaceae (previously known as the Umbelliferae) is one of the largest plant families in the world. This family comprises approximately 450 genera and 3700 species worldwide. The members of this family are well known as vegetables, culinary and medicinal plants. Members of Apiaceae possess various compounds with many biological activities. Some of the main properties are ability to induce apoptosis, antibacterial, hepatoprotective, vaso-relaxant, cyclooxygenase inhibitory and antitumor activities. In this study, 70% methanol extract prepared from the aerial parts of Eryngium billardieri, which belongs to Apiaceae family, and ethyl acetate, n-butanol fractions obtained from this extract were investigated by MTT method for cytotoxic effect on MCF7 (human breast cancer cell line) cell line. In result, the methanol extract was found more cytotoxic than fractions with 99.50 µg/mL IC50 value on MCF7 cell line.
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MDPI and ACS Style
Paşayeva, L.; Köngül, E.; Geylan, R.; Karatoprak, G.Ş.; Tugay, O. Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line. Proceedings 2017, 1, 1055. https://doi.org/10.3390/proceedings1101055
AMA Style
Paşayeva L, Köngül E, Geylan R, Karatoprak GŞ, Tugay O. Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line. Proceedings. 2017; 1(10):1055. https://doi.org/10.3390/proceedings1101055
Chicago/Turabian StylePaşayeva, Leyla, Esra Köngül, Rojen Geylan, Gökçe Şeker Karatoprak, and Osman Tugay. 2017. "Analysis of the Cytotoxic Effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line" Proceedings 1, no. 10: 1055. https://doi.org/10.3390/proceedings1101055
