“Symmetry and Minimum Principle at the Basis of the Genetic Code” Paul SORBA (LAPTH, CNRS, France) †
LAPTH (Laboratory of Annecy of Theoretical Physics), 74941 CNRS, France
†
Presented at Symmetry 2017—The First International Conference on Symmetry, Barcelona, Spain, 16–18 October 2017.
Proceedings 2018, 2(1), 58; https://doi.org/10.3390/proceedings2010058
Published: 12 January 2018
(This article belongs to the Proceedings of The First International Conference on Symmetry)
The importance of the notion of symmetry in physics is well established: could it also be the case for the genetic code? In this spirit, a model for the Genetic Code based on continuous symmetries and entitled the “Crystal Basis Model” was proposed a few years ago and applied to different problems, such as the elaboration and verification of sum rules for codon usage probabilities, relations between physico-chemical properties of amino-acids and some predictions [1]. Defining in this context a “bio-spin” structure for the nucleotids and codons, the interaction between a couple of codon-anticodon can simply be represented by a (bio) spin–spin potential. Then, imposing the minimum energy principle, an analysis of the evolution of the genetic code can be performed with good agreement with the generally accepted scheme. A more precise study of this interaction model provides information on codon bias, consistent with data [2].
Conflicts of Interest
The authors declare no conflict of interest.
References
- Frappat, L.; Sciarrino, A.; Sorba, P. Crystalizing the Genetic Code. J. Biol. Phys. 2001, 27, 1–34. [Google Scholar] [CrossRef] [PubMed]
- Sciarrino, A.; Sorba, P. A minimum principle in codon-anticodon interaction. BioSystems 2012, 107, 113–119. [Google Scholar] [CrossRef] [PubMed]
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Sorba, P. “Symmetry and Minimum Principle at the Basis of the Genetic Code” Paul SORBA (LAPTH, CNRS, France). Proceedings 2018, 2, 58. https://doi.org/10.3390/proceedings2010058
AMA Style
Sorba P. “Symmetry and Minimum Principle at the Basis of the Genetic Code” Paul SORBA (LAPTH, CNRS, France). Proceedings. 2018; 2(1):58. https://doi.org/10.3390/proceedings2010058
Chicago/Turabian StyleSorba, Paul. 2018. "“Symmetry and Minimum Principle at the Basis of the Genetic Code” Paul SORBA (LAPTH, CNRS, France)" Proceedings 2, no. 1: 58. https://doi.org/10.3390/proceedings2010058
