Welfare Assessment of Laboratory Animals

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: closed (31 March 2017) | Viewed by 6757

Special Issue Editor


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Guest Editor
Laboratory Animal Resource Center, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
Interests: animal welfare; mouse; rat; psychophysiology; affective states; laboratory animal
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The study of animal welfare is an expanding field that includes researchers from many disciplines evaluating the complexity of the whole animal. In the specialty of laboratory animal medicine and science, there is a pronounced need for more evidence based knowledge to ensure that interventions that are utilized to improve animal well-being are having the desired effect. When interventions result in a negative response in the animal, this is generally easily identified, but neutral and positive responses are not well characterized. As neutral responses can result in a waste of limited resources that could be deployed for more effective interventions, this identification is critical.

Therefore, additional studies which focus on obtaining data that incorporates an evaluation of the clinical health, behavioral responses, and affective state should be emphasized as these result in mechanisms to evaluate the whole animal.

Original papers from research areas, such as ethology, animal science, veterinary medicine, psychology and psychiatry are invited to contribute to this Special Issue about laboratory animal welfare, especially controlled interdisciplinary studies about (1) quantitative measures of human-animal interactions and acute responses to the animal during interventions, (2) the relationship between acute responses and long-term effects, and (3) whole animal assessment of animal welfare (clinical health, behavioral responses, and affective state).

Dr. Debra Hickman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Article
Long Term Physiologic and Behavioural Effects of Housing Density and Environmental Resource Provision for Adult Male and Female Sprague Dawley Rats
by Christopher J. Pinelli, Francesco Leri and Patricia V. Turner
Animals 2017, 7(6), 44; https://doi.org/10.3390/ani7060044 - 01 Jun 2017
Cited by 16 | Viewed by 6163
Abstract
There is considerable interest in refining laboratory rodent environments to promote animal well-being, as well as research reproducibility. Few studies have evaluated the long term impact of enhancing rodent environments with resources and additional cagemates. To that end, male and female Sprague Dawley [...] Read more.
There is considerable interest in refining laboratory rodent environments to promote animal well-being, as well as research reproducibility. Few studies have evaluated the long term impact of enhancing rodent environments with resources and additional cagemates. To that end, male and female Sprague Dawley (SD) rats were housed singly (n = 8/sex), in pairs (n = 16/sex), or in groups of four (n = 16/sex) for five months. Single and paired rats were housed in standard cages with a nylon chew toy, while group-housed rats were kept in double-wide cages with two PVC shelters and a nylon chew toy and were provided with food enrichment three times weekly. Animal behaviour, tests of anxiety (open field, elevated plus maze, and thermal nociception), and aspects of animal physiology (fecal corticoid levels, body weight, weekly food consumption, organ weights, and cerebral stress signaling peptide and receptor mRNA levels) were measured. Significant differences were noted, primarily in behavioural data, with sustained positive social interactions and engagement with environmental resources noted throughout the study. These results suggest that modest enhancements in the environment of both male and female SD rats may be beneficial to their well-being, while introducing minimal variation in other aspects of behavioural or physiologic responses. Full article
(This article belongs to the Special Issue Welfare Assessment of Laboratory Animals)
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