5th Anniversary of 'Applied Biosciences and Bioengineering' Section—Recent Advances in Extracellular Vesicles and Innate Immune System-Engineered Extracellular Vesicles as a Potential Immuno-Therapeutic Tool

Dear Colleagues,

Recently, great interest has been expressed in extracellular vesicles (EVs), heterogeneous structures enclosed by phospholipid membranes. Exosomes constitute a subset of extracellular vesicles (EVs) and can be released from almost all cell types. Exosomes efficiently transport functional components to recipient cells. The innate immune system plays a crucial role in host defense against viral and microbial infections. Evidence has shown that exosomes derived from tumor cells, host cells and bacteria mediate communication between the invader and innate immune cells and play an important role in the spread of pathogens by modulating the innate response. The Special Issue aims to compile current knowledge on EVs (especially exosomes) and their role in determining innate immune responses.

Cells can be genetically engineered to produce EVs that carry specific target and/or therapeutic molecules, offering important opportunities for biomedical applications of EVs.

Dr. Giovanna Traina
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• extracellular vesicles
• exosomes
• innate immune system
• mast cells
• macrophages
• autoimmunity
• therapeutic potential