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Biomedicines
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The Interplay between Immunity and Microbiota in Human Health and...
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The Interplay between Immunity and Microbiota in Human Health and Diseases (2nd Edition)

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1408

Special Issue Editor

Dr. Laura Franza

E-Mail
Guest Editor
Department of Emergency Medicine, Fondazione Policlinico Universitario, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Interests: inflammation; microbiota; immunology; sepsis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The importance of microbiota in determining health and disease is a topic that has gained more and more visibility over the last few years. Microbiota has been implied in many gastrointestinal conditions, but also in other disorders—for instance, autoimmune diseases and even cancer in some cases. In particular, microbiota appears to play an important role in modulating immune response.

The full extent of the importance of microbiota, though, is still not completely understood, and many areas are still grey in this field. In this Special Issue, we hope to collect relevant papers focusing on the role of microbiota in different conditions. Authors are welcome to send different types of articles, focusing on microbiota and its role in different conditions. We encourage authors to focus on the role of the immune system in these interactions.

Dr. Laura Franza
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunity
  • microbiota
  • inflammation
  • infection
  • cancer
  • autoimmune disorders
  • disease

Published Papers (1 paper)

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Review

19 pages, 699 KiB  
Review
Maternal-Foetal/Infant Interactions—Gut Microbiota and Immune Health
by Ada Maria Adamczak, Alicja Werblińska, Małgorzata Jamka and Jarosław Walkowiak
Biomedicines 2024, 12(3), 490; https://doi.org/10.3390/biomedicines12030490 - 22 Feb 2024
Viewed by 1149
Abstract
In recent years, the number of scientific publications on the role of intestinal microbiota in shaping human health, as well as the occurrence of intestinal dysbiosis in various disease entities, has increased dynamically. However, there is a gap in comprehensively understanding the factors [...] Read more.
In recent years, the number of scientific publications on the role of intestinal microbiota in shaping human health, as well as the occurrence of intestinal dysbiosis in various disease entities, has increased dynamically. However, there is a gap in comprehensively understanding the factors influencing a child’s gut microbiota. This review discusses the establishment of gut microbiota and the immunological mechanisms regulating children’s microbiota, emphasising the importance of prioritising the development of appropriate gut microbiota in a child from the planning stages of pregnancy. The databases PubMed, Web of Sciences, Cochrane, Scopus and Google Scholar were searched to identify relevant articles. A child’s gut microbiota composition is influenced by numerous factors, such as diet during pregnancy, antibiotic therapy, the mother’s vaginal microbiota, delivery method, and, later, feeding method and environmental factors. During pregnancy, the foetus naturally acquires bacterial strains from the mother through the placenta, thereby shaping the newborn’s immune system. Inappropriate maternal vaginal microbiota may increase the risk of preterm birth. Formula-fed infants typically exhibit a more diverse microbiota than their breastfed counterparts. These factors, among others, shape the maturation of the child’s immune system, impacting the production of IgA antibodies that are central to cellular humoral immune defence. Further research should focus on identifying specific microbiota–immune system interactions influencing a child’s immune health and developing personalised treatment strategies for immune-related disorders. Full article
(This article belongs to the Special Issue The Interplay between Immunity and Microbiota in Human Health and Diseases (2nd Edition))
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