Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 15 July 2024 | Viewed by 738
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diseases of the gastrointestinal tract encompass a wide range of disorders that affect the digestive system, and they have attracted the attention of researchers and health professionals around the world. The cellular and molecular mechanisms underlying these diseases, such as inflammatory bowel diseases, irritable bowel syndrome, gastroesophageal reflux, peptic ulcer, celiac disease, gastrointestinal motility disorders, liver diseases, and others, are diverse and involve various components of the gastrointestinal tract. Papers addressing gastrointestinal comorbidities are also welcome in this Special Issue. Cell targets are present in the epithelial barriers, mucosal tissues, accessory glands, immune system, enteric nervous system, neuromuscular junctions, and others. Molecular signaling includes mechanisms that regulate inflammation (cytokines and chemokines), fibrosis, aberrant immune responses, genetic susceptibility, abnormalities in the gut–brain axis, visceral hypersensitivity, pathogens, disruption of mucosa, cancer, smooth muscle abnormalities, and others. Understanding these cellular and molecular mechanisms is crucial for developing targeted therapies, diagnostic tools, and interventions for the diverse array of gastrointestinal diseases resulting in precision medicine and personalized treatment approaches. Studies in this area involve the oral cavity, esophagus, stomach, small and large intestines, salivary glands, liver, pancreas, and gallbladder. This Special Issue aims to improve both preventive and therapeutic protocols and methodologies for precision diagnosis. Advances in molecular and cell biology in gastrointestinal diseases continue to enhance our understanding of these mechanisms and drive innovation in medical research and healthcare. Papers on other topics linked to gastrointestinal tract diseases not included here, however, will also be considered by the editorial team.
Dr. Felipe Leite De Oliveira
Guest Editor
Manuscript Submission Information
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Keywords
- cellular mechanisms
- molecular mechanisms
- diagnosis
- treatment
- experimental models
- signaling pathways
- comorbidities
