RNA Biology: From Genome to Therapeutic Targets

Dear Colleagues,

Biological data analysis of RNA (ribonucleic acid) is a crucial aspect of modern molecular biology research, as RNA plays key roles in gene expression and regulation. The analysis of RNA data aims to understand gene expression patterns, detect changes in gene expression levels, and identify novel RNA species and post-transcriptional modifications.

Advances in high-throughput sequencing technologies have greatly expanded the body of RNA data available for analysis, providing a wealth of information about the transcriptomes. However, analysing this large body of data can be challenging, as it requires the development of sophisticated computational tools and algorithms. The current frontiers of RNA data analysis include the development of methods for the detection of differential gene expressions and the identification and characterization of novel RNA species, including non-coding RNAs, long non-coding RNAs, and circular RNA, additionally enabling the detection of new microbiome species using 16sRNA. New techniques, such as single-cell RNA sequencing, have enabled the analysis of gene expression on the single-cell level, providing a more detailed and accurate picture of gene expression patterns, with single-cell RNA sequencing being most recent technology to be widely used in cancer studies (not limited) to explore the microenvironments of tumour cells.

Overall, the analysis of RNA data is a rapidly evolving field, with new techniques and methods being developed in order to better understand gene expression and regulation. The results of these studies have important implications for our understanding of biological processes, the development of new therapies, and the diagnosis and treatment of diseases.

For this Special Issue, we invite authors to submit original research and review manuscripts aiming to present the most recent advances in RNA biological data analysis.

Dr. Yogesh Kumar
Dr. Sugandh Kumar
Dr. Bharati Mehani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• RNA
• decoding
• single-cell RNA
• non-coding RNA
• SiRNA
• 16sRNA
• RNA data analysis
• microbiome