Mitochondria and Immunometabolism in Cancer

Dear Colleagues,

This Special Issue, titled “Mitochondria and Immunometabolism in Cancer”, will focus on the role of mitochondria and their metabolic function in the crosstalk between cancer and immune cells.

A new perspective on the survival of cancer cells and the mechanisms underlying tumor progression has recently involved tumor microenvironmental cells. The hallmark of both cancer and activated immune cells is metabolic reprogramming, which depends on gene expression regulation in response to the rise in energetic demands and the need for specific metabolites. A focal point of these metabolic changes is the mitochondrial metabolism supplying energy and metabolites necessary for cell growth.

In this context, it is crucial to comprehend the relationship between cancer and microenvironmental cells, providing a new possible strategy for immunotreatments of cancer. We invite researchers to contribute to this Special Issue with original research or review articles focusing on mitochondrial metabolism, bioenergetics, mitochondrial signaling and immunometabolism in cancer.

This Special Issue includes, but is not limited to, the following topics:

1. Immunometabolism;
2. Bioenergetics;
3. Mitochondrial metabolism;
4. Cell signaling;
5. Mitochondrial signaling;
6. Cancer cell metabolism;
7. Cancer cells- immune cells crosstalk;
8. Gene expression regulation;
9. Tumor microenvironment.

Dr. Simona Todisco
Dr. Santarsiero Anna
Dr. Paolo Convertini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• immunometabolism
• bioenergetics
• mitochondrial metabolism
• cell signaling
• mitochondrial signaling
• cancer cell metabolism
• cancer cells–immune cells crosstalk
• gene expression regulation
• tumor microenvironment