Nano-Bio Interface Toxicity and Applications 2.0

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Nanomedicine and Nanobiology".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 3848

Special Issue Editors


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Guest Editor
Biophysics Group, Department of Physics and Astronomy, University College London, London, UK
Interests: nanomaterials; biomolecular sciences; biomedical sciences; nanotechnology
Centre for Materials Science, University of Central Lancashire, Lancashire, UK
Interests: functional nanomaterials; nano-biomaterials; nanomedicine; nano-catalysis and green technology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The fate of nanomaterials in a biological environment for their applications in medicine is currently a hot topic due to the formation of protein corona, which limits their use in biomedicine. Therefore, functionalisation of inorganic/organic nanoparticles with biomolecules such as oligonucleotides, antibodies, protein and disease specific biomarkers is a topical area of research receiving a huge amount of interest from experts in biomedicine. In this Special Issue, we welcome research articles, communications and reviews on application of functional nanomaterials in biomedicine by exploring the formation of protein corona, in the nano–bio interface, a range of biomolecules conjugated nanoparticles and their toxicity.

Prof. Dr. Nguyen T.K. Thanh
Dr. Tapas Sen
Guest Editors

Manuscript Submission Information

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Keywords

  • nano–bio interface
  • protein corona
  • toxicity
  • biomarkers
  • nanomedicine
  • theranostic

Published Papers (1 paper)

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Review

26 pages, 4402 KiB  
Review
Advancement in Nanostructure-Based Tissue-Engineered Biomaterials for Retinal Degenerative Diseases
by Sonali Suresh Rohiwal, Zdenka Ellederová, Taras Ardan and Jiri Klima
Biomedicines 2021, 9(8), 1005; https://doi.org/10.3390/biomedicines9081005 - 13 Aug 2021
Cited by 8 | Viewed by 3187
Abstract
The review intends to overview a wide range of nanostructured natural, synthetic and biological membrane implants for tissue engineering to help in retinal degenerative diseases. Herein, we discuss the transplantation strategies and the new development of material in combination with cells such as [...] Read more.
The review intends to overview a wide range of nanostructured natural, synthetic and biological membrane implants for tissue engineering to help in retinal degenerative diseases. Herein, we discuss the transplantation strategies and the new development of material in combination with cells such as induced pluripotent stem cells (iPSC), mature retinal cells, adult stem cells, retinal progenitors, fetal retinal cells, or retinal pigment epithelial (RPE) sheets, etc. to be delivered into the subretinal space. Retinitis pigmentosa and age-related macular degeneration (AMD) are the most common retinal diseases resulting in vision impairment or blindness by permanent loss in photoreceptor cells. Currently, there are no therapies that can repair permanent vision loss, and the available treatments can only delay the advancement of retinal degeneration. The delivery of cell-based nanostructure scaffolds has been presented to enrich cell survival and direct cell differentiation in a range of retinal degenerative models. In this review, we sum up the research findings on different types of nanostructure scaffolds/substrate or material-based implants, with or without cells, used to deliver into the subretinal space for retinal diseases. Though, clinical and pre-clinical trials are still needed for these transplants to be used as a clinical treatment method for retinal degeneration. Full article
(This article belongs to the Special Issue Nano-Bio Interface Toxicity and Applications 2.0)
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